scholarly journals Side effects of COVID-19 vaccines in paraguayan health personnel: exploratory study

2021 ◽  
Vol 11 (2) ◽  
pp. 24-29
Author(s):  
Carlos Miguel Rios-González ◽  
Julieta Mendez ◽  
Gladys Estigarribia ◽  
Gloria Aguilar ◽  
Pablo Martínez
Keyword(s):  
Side Effects ◽  
Exploratory Study ◽  
Health Personnel

scholarly journals Targeting Engineered Nanoparticles for Breast Cancer Therapy

Pharmaceutics ◽  
2021 ◽  
Vol 13 (11) ◽  
pp. 1829
Author(s):  
Kumar Ganesan ◽  
Yan Wang ◽  
Fei Gao ◽  
Qingqing Liu ◽  
Chen Zhang ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Side Effects ◽  
Exploratory Study ◽  
Engineered Nanoparticles ◽  
Therapeutic Effects ◽  
Breast Cancer Therapy ◽  
Normal Tissues ◽  
Therapeutic Drugs ◽  
Common Cancer ◽  
Important Approach

Breast cancer (BC) is the second most common cancer in women globally after lung cancer. Presently, the most important approach for BC treatment consists of surgery, followed by radiotherapy and chemotherapy. The latter therapeutic methods are often unsuccessful in the treatment of BC because of their various side effects and the damage incurred to healthy tissues and organs. Currently, numerous nanoparticles (NPs) have been identified and synthesized to selectively target BC cells without causing any impairments to the adjacent normal tissues or organs. Based on an exploratory study, this comprehensive review aims to provide information on engineered NPs and their payloads as promising tools in the treatment of BC. Therapeutic drugs or natural bioactive compounds generally incorporate engineered NPs of ideal sizes and shapes to enhance their solubility, circulatory half-life, and biodistribution, while reducing their side effects and immunogenicity. Furthermore, ligands such as peptides, antibodies, and nucleic acids on the surface of NPs precisely target BC cells. Studies on the synthesis of engineered NPs and their impact on BC were obtained from PubMed, Science Direct, and Google Scholar. This review provides insights on the importance of engineered NPs and their methodology for validation as a next-generation platform with preventive and therapeutic effects against BC.

Dignity of Person in the Final Phase of Life - An Exploratory Study

1977 ◽  
Vol 8 (1) ◽  
pp. 71-80 ◽  
Author(s):  
Mary Louise Nash
Keyword(s):  
Exploratory Study ◽  
Health Personnel ◽  
Chronic Care ◽  
Terminal Phase ◽  
Final Phase ◽  
Consciousness Raising ◽  
Human Needs ◽  
Care Institution

An attempt was made to identify those factors which affect the “dignity” of a person when in the advanced or terminal phase of illness. A series of interviews (140 in all) was conducted with 24 adults in a large chronic care institution. Emphasis was on the informant's world of meaning. Only 10% of the coded responses could be classified as indicative of a sense of affirmed dignity. The most frequent non-dignity supportive responses were indicative of pain, loss, loneliness, and intrusiveness. Results of this exploratory study underline the necessity to promote consciousness-raising of health personnel about the human needs of persons who are in the final phase of their lives.

scholarly journals Assistência ao trabalho de parto, parto e pós-parto de adolescentes

2019 ◽  
Vol 13 ◽  
Author(s):  
João Victor Lira Dourado ◽  
Perpétua Alexsandra Araújo ◽  
Francisca Alanny Rocha Aguiar
Keyword(s):  
Health Care ◽  
Health Professionals ◽  
Maternity Care ◽  
Exploratory Study ◽  
Health Personnel ◽  
Structured Interview ◽  
Qualitative Descriptive ◽  
La Red ◽  
Maternity Health

Objetivo: analisar a qualidade da assistência ao trabalho de parto, parto e pós-parto de adolescentes. Método: trata-se de um estudo qualitativo, descritivo e exploratório. Constituir-se-ão, como população, adolescentes puérperas da unidade de internação obstétrica. Aplicar-se-á, para a coleta de informações, a entrevista semiestruturada em profundidade guiada por um instrumento. Utilizar-se-á, na análise das informações a Análise Temática. Resultados esperados: pretende-se compreender os cuidados de saúde dispensados pelos profissionais de saúde às adolescentes, construir indicadores da qualidade da assistência em maternidade, reorganizar a rede assistencial a partir das particularidades das adolescentes, evidenciar a necessidade da elaboração e implementação de políticas públicas que as assegurem como sujeito social em todas as dimensões e incitar outros investigadores para o desenvolvimento de novos estudos no país. Descritores: Adolescentes; Maternidades; Pessoal de Saúde; Qualidade da Assistência à Saúde; Saúde da Mulher; Parto.AbstractObjective: to analyze the quality of assistance to labor, delivery and postpartum in adolescents. Method: this is a qualitative, descriptive and exploratory study. The population will consist of postpartum adolescents from the obstetric inpatient unit. For information gathering, an in-depth semi-structured interview guided by an instrument will be applied. The analysis will use the Thematic Analysis. Expected results: it is intended to understand the health care provided by health professionals to adolescents, to build indicators of the quality of maternity care, to reorganize the care network based on the particularities of adolescents, to highlight the need for the elaboration and implementation of public policies that ensure them as a social subject in all dimensions and encourage other researchers to develop new studies in the country. Descriptors: Adolescent; Hospitals, Maternity; Health Personnel; Quality of Health Care; Women's Health; Parturition.ResumenObjetivo: analizar la calidad de la asistencia al parto, parto y posparto en adolescentes. Método: este es un estudio cualitativo, descriptivo y exploratorio. La población estará compuesta por adolescentes puérperas de la unidad de hospitalización obstétrica. Para la recopilación de información, se aplicará una entrevista semiestructurada en profundidad guiada por un instrumento. Para el análisis de las informaciones se utilizará el Análisis Temático. Resultados esperados: se pretende comprender la atención médica brindada por los profesionales de la salud a los adolescentes, construir indicadores de la calidad de la atención de maternidad, reorganizar la red de atención basada en las particularidades de las adolescentes, resaltar la necesidad de la elaboración e implementación de políticas públicas que las asegure como un sujeto social en todas las dimensiones y aliente a otros investigadores a desarrollar nuevos estudios en el país. Descriptores: Adolescente; Maternidades; Personal de Salud; Calidad de la Atención de Salud; Salud de la Mujer; Parto.

Gastric Ulcers Produced by Cisplatin

1981 ◽  
Vol 39 ◽  
pp. 582-583
Author(s):  
S.K. Aggarwal ◽  
J. San Antonio
Keyword(s):  
Electron Microscopy ◽  
Single Dose ◽  
Side Effects ◽  
Antitumor Agent ◽  
Gastric Ulcers ◽  
Enzyme Cytochemistry ◽  
Intestinal Toxicity ◽  
Ovarian Cancers ◽  
Inner Surface

Cisplatin (cis-dichlorodiammineplatinum(II)) a potent antitumor agent is now available for the treatment of testicular and ovarian cancers. It is however, not free from its serious side effects including nephrotoxicity, gastro intestinal toxicity, myelosuppression, and ototoxicity. Here we now report that the drug produces peculiar bloating of the stomach in rats and induces acute ulceration.Wistar-derived rats weighing 200-250 g were administered cisplatin(9 mg/kg) ip as a single dose in 0.15 M NaCl. After 3 days the animals were sacrificed by decapitation. The stomachs were removed, the contents analyzed for pepsin and acidity. The inner surface was examined with a dissecting microscope after a moderate stretching for ulcers. Affected areas were fixed and processed for routine electron microscopy and enzyme cytochemistry.The drug treated animals kept on food and water consistently showed bloating and lesions (Fig. 1) with a frequency of 6-70 ulcers in the rumen section of the stomachs.

Effects of cisplatin treatment on the rat neurohypophysis

1986 ◽  
Vol 44 ◽  
pp. 122-123
Author(s):  
J.M. Fadool ◽  
P.J. Boyer ◽  
S.K. Aggarwal
Keyword(s):  
Side Effects ◽  
Urine Output ◽  
Morphological Changes ◽  
Limiting Factor ◽  
Antineoplastic Drugs

Cisplatin (CDDP) is currently one of the most valuable antineoplastic drugs available. However, it has severe toxic side effects of which nephrotoxicity is the major dose limiting factor in its use. It induces morphological changes in the kidney with hampered urine output. The present study is an effort to determine the influence of the drug on the neurohypophysis for any antidiuretic effects on the kidney.

A hospital clerkship program for dental students: an exploratory study

1969 ◽  
Vol 33 (2) ◽  
pp. 224-229
Author(s):  
EA Stuebner ◽  
RP Johnson
Keyword(s):  
Exploratory Study ◽  
Dental Students

Errors in federal report on dental health personnel present problems

1990 ◽  
Vol 54 (12) ◽  
pp. 723-723
Author(s):  
IC Bennett ◽  
MA Boyd
Keyword(s):  
Health Personnel ◽  
Dental Health
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