Synthesis and Characterization of Fully Substituted Pyrimidines by Using Ketene Dithioacetal as Potent Antimicrobial Agent
2013 ◽
Vol 24
◽
pp. 134-141
Keyword(s):
Various ketene dithioacetals of acetoacetanilides were reacted with guanidine nitrate in the presence of base to produce the 2-amino-4-isopropyl-6-alkoxy-N-arylpyrimidine-5-carboxamide derivatives with good yields. All the synthesized compounds were characterized by mass, NMR and IR and also evaluated for antimicrobial activity against five different bacterial and fungal strains. The compounds 4i, 4k and 4l has found comparatively good active against all the bacterial strains.
2014 ◽
Vol 40
◽
pp. 73-80
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2015 ◽
Vol 43
◽
pp. 41-48
2018 ◽
Vol 9
◽
pp. 69-77
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2016 ◽
Vol 74
◽
pp. 81-90
◽
2020 ◽
pp. 125-134
2021 ◽
Keyword(s):