scholarly journals Comparative study between bone ages: Carpal, Metacarpophalangic, Carpometacarpophalangic Ebrí, Greulich and Pyle and Tanner Whitehouse2

2021 ◽  
Vol 9 (12) ◽  
Author(s):  
Bernardo Torné

We have carried out a review study in order to remind the pediatrician of the differences in bone age (EO) between the existing Greulich-Pyle (GP) or Tanner-Whitehouse 2 (TW2) methods compared to Ebrí ages: EO Ebrí-carpal (EOIC) metacarpophalangic (EOIMF) and Carpometacarpophalangic (EOICMF). The study was carried out in Spanish longitudinal casuistry “Andrea Prader”. It comprises 160 healthy children: 73 males and 87 females, distributed by sex and age from 0.5 to 20 years. By obtaining the EO for each method, a comprehensive study can be carried out between them, and thus, observing if there are differences, being able to offer a quantification to the pediatrician for him to take them into account. In previous studies, the equations for obtaining the EO were expressed by the Ebrí methods. These quantifications are presented throughout this review.

1993 ◽  
Vol 14 (4) ◽  
pp. 133-158

Skeletal maturation is expressed as bone age or skeletal age. Bone age is based on the orderly appearance of the ossification centers and, therefore, on the successive stages of the development (or maturity) of the skeleton as seen on radiographs. This is not a measure of size, but rather of shape and position. There are many methods of estimating bone age, and almost any part of the body can be used. The hand and wrist are the most practical and the most often used. The Greulich and Pyle method employs an atlas of examples of radiographs of the entire left hand and wrist of healthy children at various ages.


2018 ◽  
Vol 100-B (8) ◽  
pp. 1106-1111 ◽  
Author(s):  
D. M. Knapik ◽  
J. O. Sanders ◽  
A. Gilmore ◽  
D. R. Weber ◽  
D. R. Cooperman ◽  
...  

Aims Using 90% of final height as a benchmark, we sought to develop a quick, quantitative and reproducible method of estimating skeletal maturity based on topographical changes in the distal femoral physis. Patients and Methods Serial radiographs of the distal femoral physis three years prior to, during, and two years following the chronological age associated with 90% of final height were analyzed in 81 healthy children. The distance from the tip of the central peak of the distal femoral physis to a line drawn across the physis was normalized to the physeal width. Results A total of 389 radiographs of the distal femur with corresponding Greulich and Pyle bone ages and known chronological ages were measured. Children reached 90% of final height at a mean age of 11.3 years (sd 0.8) for girls and 13.2 years (sd 0.6) for boys. Linear regression analysis showed higher correlation coefficent in predicting the true age at 90% of final height using chronological age + gender + central peak value (R2 = 0.900) than chronological age + gender (R2 = 0.879) and Greulich and Pyle bone age + gender (R2 = 0.878). Conclusion Chronological age + gender + central peak value provides more accurate prediction of 90% of final height compared with chronological age + gender and Greulich and Pyle bone age + gender. Cite this article: Bone Joint J 2018;100-B:1106–11.


2020 ◽  
Vol 23 (2) ◽  
pp. 222-234
Author(s):  
Shaafan Taher ◽  
◽  
SHEYAN ALYOUSIFY ◽  
Hussein Hassan ◽  
◽  
...  

2020 ◽  
Vol 26 (3) ◽  
pp. 328-331 ◽  
Author(s):  
Kelsey B. Eitel ◽  
Erica A. Eugster

Objective: Pediatric endocrinologists (PEs) have historically read their own bone age (BA) X-rays based on the belief that radiologists do not accurately interpret these tests. Whether there are significant differences in BA interpretations between these two groups has not been systematically explored. The objectives of the study were to compare BA readings performed by PEs and radiologists and determine whether clinical variables were associated with discrepancies in readings. Methods: A retrospective chart review of children presenting for initial evaluation of short stature (SS) or precocious puberty (PP) who had a BA X-ray completed was performed. Clinical variables analyzed included age, gender, ethnicity, Tanner stage, body mass index, reason for referral, radiologist location (Children's vs. outside hospital), and PE and radiologist BA readings using the Greulich and Pyle method. Results: Of 103 patients aged 9 ± 3.66 years, there was a discrepancy between the PE and radiologist readings on 70 images (68%). Discrepancy ranged from −1.5 to 3.5 years, with a mean of 4 ± 12 months. Patients referred for PP were more likely to have discrepant interpretations than those referred for SS (8.4 months vs. 0.8 months; P = .007). No differences were seen in interpretations between in-house radiologists and those at outside hospitals. Conclusion: Radiologists interpreted BAs differently than PEs in the majority of images. In patients referred for PP, BAs were interpreted as being older by radiologists than by PEs, perhaps due to bias from the reason for referral. Our results provide support for continued independent BA interpretations by PEs. Abbreviations: BA = bone age; GP = Greulich and Pyle; PE = pediatric endocrinologist; PP = precocious puberty; SS = short stature


2017 ◽  
Vol 35 (15_suppl) ◽  
pp. 10554-10554
Author(s):  
Hermann L. Müller ◽  
Johannes H.M. Merks ◽  
Birgit Geoerger ◽  
Jacques Grill ◽  
Darren Hargrave ◽  
...  

10554 Background: BEV has an established safety profile in adults, but long-term data in children are limited. This analysis examined the effects of BEV on growth/development in pediatric/adolescent pts. Methods: Data (height, weight, body mass index [BMI], bone age data) were pooled (5 trials): NCT00643565 (Ph2/soft tissue sarcoma); NCT01390948 (Ph2/high-grade glioma); NCT00085111 (Ph1/refractory solid tumors); NCT00667342 (Ph2/osteosarcoma); NCT00381797 (Ph2/glioma, medulloblastoma, ependymoma). Pts (<18 yrs old) received ≥1 dose of BEV + chemotherapy (CT) (n=268) or CT alone (n=135). Analyses were exploratory/descriptive. Reference growth data: WHO (<2 yrs); Centres for Disease Control (≥2 yrs). Results: Across the trials, mean number of BEV administrations per pt ranged 5.6–19.9 (dose 5–15mg/kg every 2/3 weeks). Median follow-up time, months (range): BEV+CT, 37.9 (2.4–64.2); CT, 22.9 (2.8–69.2). At baseline, median height, weight, and BMI were close to that of the reference population (mean standard deviation scores [SDS] close to 0). Over 60 months, a slight decline was observed in the mean SDS for height and weight in both arms in this cohort with different tumors/treatments (Table), but remained within normal range of healthy children. Trends were similar for BMI. No delay in growth velocity or bone age in BEV-treated pts vs CT only was observed up to 3 yrs, regardless of age/gender. A subgroup analysis of pts in the growth hormone-dependent development phase was consistent with the overall results. Conclusions: In this analysis, BEV inclusion in the treatment regimen did not have a negative impact on pediatric growth/development beyond that of CT alone. [Table: see text]


1986 ◽  
Vol 37 (2) ◽  
pp. 119-121 ◽  
Author(s):  
G.R. Milner ◽  
R.K. Levick ◽  
R. Kay
Keyword(s):  
Bone Age ◽  

2015 ◽  
Vol 44 (9) ◽  
pp. 1351-1356 ◽  
Author(s):  
Parisa Hajalioghli ◽  
Mohammad Kazem Tarzamni ◽  
Sara Arami ◽  
Daniel Fadaei Fouladi ◽  
Morteza Ghojazadeh

1996 ◽  
Vol 76 (2) ◽  
pp. 183-197 ◽  
Author(s):  
M. B. Duggan ◽  
L. Harbottle

Detailed anthropometric measurements were made on 169 healthy children aged between 4 and 40 months during a comprehensive study of the diet and nutritional status of Asian children (of Pakistani and Bangladeshi origin) living in Sheffield. These measurements were used to describe the growth profile of these apparently healthy children and to compare this with both international and UK reference data. The distribution of values for most anthropometric measurements was close to the UK reference data although both boys and girls tended to be slight of build, and girls tended to have relatively smaller head circumferences. Nevertheless, it was concluded that their growth and nutritional status over this age range can be evaluated using standard (UK) growth charts


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