scholarly journals Seroprevalence of Chlamydia trachomatis infection among pregnant women and their outcome

Author(s):  
Vibha Rani Pipal ◽  
Rajendra Pipal ◽  
Dharmendra Pipal ◽  
Seema Yadav ◽  
Manoj Kamal ◽  
...  

Background: Genitourinary infections either sexually transmitted or by other means are a major concern among women, particularly young adults and teens. The objective was to find out seroprevalence of Chlamydia trachomatis infection in pregnant women and its effect on pregnancy outcome.Methods: the present study was carried out in the department of obstetrics and gynaecology, King George Medical University of Lucknow, Uttar Pradesh, India, over a period of September 2003 to July 2004. Total 120 pregnant women were included in the study, these pregnant women were selected according to their will in taking part in the study irrespective of age and parity. 2 ml of blood sample was collected and determination of antichlamydial IgM antibody was done by VIRCELL SL IgM ELISA Kit in microbiology department. Prevalence of chlamydia trachomatis in pregnant women were assessed and correlated with age group, parity, socioeconomic status, previous obstetric outcome, anaemia, PROM, mode of termination according to gestational age, perinatal outcome regards birthweight, and adverse neonatal outcome.Results: Out of 120 cases, total 70 (58.33%) were positive while the remaining 50 cases were negative. 80 cases were followed till delivery in which 66.25% were positive for antichlamydial IgM antibody. There was significant association of previous history of 2-3 abortion and preterm delivery with IgM positive cases. Low birth weight deliveries were 78% and very low birth weight was 100% in positive cases. Caesarean section at <37 weeks of gestation, IUGR and low APGAR score were significantly high in IgM positive group. 100% PROM cases were IgM positive.Conclusions: The prevalence of chlamydia trachomatis infection among pregnant women in our population is high and is strongly associated with premature rupture of membranes, IUGR, LBW, and low APGAR score deliveries.

2021 ◽  
Vol 15 (10) ◽  
pp. 3423-3425
Author(s):  
Amna Najam ◽  
Samreen Fakeer Muhammad ◽  
Samia Saifullah ◽  
Maryam Shoaib ◽  
Maria Anwar

Objective: The aim of this study is to compare the fetal and maternal outcomes in between asymptomatic and symptomatic COVID positive pregnant women. Study Design: Retrospective cohort study Place and Duration: The study was conducted at Gynae and Obs department of Sandeman Provincial Hospital, Quetta for duration of six months from November 2020 to April 2021. Methods: One hundred and ten pregnant women with ages 18-45 years had corona virus disease were presented. Informed written consent was taken from all patients for detailed demographics. COVID -19 was diagnosed by PCR. 55 patients had symptoms of coronavirus were included in group A and 55 patients did not show symptoms were included in group B. Frequency of pre-eclampsia, gestational diabetes mellitus and post-partum haemorrhage were calculated. Maternal adverse outcomes (cesarean section, instrumental delivery, induction of labor and prolong labor, hypertensive disorder) were calculated among both groups. Fetal outcomes perinatal mortality, Low birth weight, Low Apgar score and NICU admission were observed. SPSS 20.0 version was used to analyze all data. Results: Mean age of the patients in group A was 28.47±3.18 years with mean BMI 24.03±5.24 Kg/m2 and in group B mean age was 27.99±4.17 years with mean BMI 24.44±6.41 Kg/m2. Maternal outcomes (cesarean section, instrumental delivery, induction of labor and prolong labor,) in symptomatic group were significantly higher than that of asymptomatic group. Fetal outcomes, perinatal mortality in group A 9 (16.4%) and in group B was 5 (9.1%), low birth weight in group A was among 21 (38.2%) and in group B was 10 (18.2%), low apgar score in group A was 11 (20%) and in group B was 8 (14.4%), 15 (27.3%) in group A went to NICU admission and 3 (5.5%) patient in group II admitted to NICU. Conclusion: In this study we concluded that adverse outcomes among symptomatic COVID pregnant women were higher than that of asymptomatic coronavirus pregnant women in terms maternal and perinatal outcomes. Keywords: Pregnant women, Coronavirus, Symptomatic, Asymptomatic, Adverse Outcomes


2021 ◽  
Author(s):  
Baoquan Zhang ◽  
Xiujuan Chen ◽  
Changyi Yang ◽  
Huiying Shi ◽  
Wenlong Xiu ◽  
...  

Abstract Purpose This study was designed to investigate the effects of hypertensive disorders of pregnancy (HDP) on the mortality and complications in very low birth weight neonates. Methods Premature infants at a gestational age of < 37 weeks with a birth weight of < 1,500g were included in this retrospective analysis. Gestational age-matched pregnant women with normal blood pressure giving birth to a very low birth weight neonate served as normal control. HDP neonates were divided into three subgroups based on the disease severity, including gestational hypertension, pre-eclampsia and eclampsia. Then we compared the incidence of complications among three subgroups. We also analyzed the relationship between the subgroups and the neonatal prognosis. Results The incidence of fetal distress, small for gestational age (SGA), mechanical ventilation, neonatal respiratory distress syndrome (RDS), neonatal necrotizing enterocolitis (NEC, ≥ 2 stage), and mortality in HDP group were significantly higher than those of the control. The 1 min Apgar score in HDP group was significantly lower than that of the normal control (P < 0.05). There were significant differences in fetal distress, 1 min Apgar score, mechanical ventilation, RDS and NEC (≥ 2 stage) among HDP, pre-eclampsia and eclampsia subgroups (P < 0.05). Multivariate regression analysis indicated that pre-eclampsia was an independent risk factor for SGA (OR = 4.123, 95%CI: 2.783–6.109) and NEC (OR = 2.493, 95%CI: 1.161–5.351). Eclampsia was a risk factor for SGA (OR = 3.804, 95%CI: 1.239–11.681) and NEC (OR = 7.264, 95%CI: 1.771–29.797). Conclusions HDP may affect the prognosis of very low birth weight neonates. Pre-eclampsia and eclampsia were risk factors for SGA and NEC.


Author(s):  
Helen Trotman ◽  
Maureen Samms-Vaughan ◽  
Charlene Coore-Desai ◽  
Jody-Ann Reece ◽  
Oluwayomi Olugbuyi

Objective The study aimed to determine the outcome of babies born to women ≥40 years in a Jamaican birth cohort. Patients and Methods Maternal demographic data and neonatal data for women ≥40 years who delivered live singleton babies and their younger counterparts aged 20 30 years were extracted from the JA KIDS birth cohort dataset. Outcome measures were preterm birth, low birth weight, very low birth weight, extremely low birth weight, macrosomia, a low 5-minute Apgar score <7, admission to the neonatal unit, and neonatal death. Descriptive analyses were performed; statistical significance was taken at the level p <0.05. Results A total of 5,424 women and their babies were entered into the study, 5,099 (94%) women were aged 20 to 30 years (mean age ± standard deviation [SD]: 24.5 ± 3.2 years) and 325 (6%) were aged ≥40 years (mean age ± SD: 41.5 ± 1.6 years). A greater percentage of preterm babies (18%) were born to women ≥40 years than to their younger counterparts (14%; p = 0.04). There was no difference in the proportion of low birth weight infants, very low birth weight infants, or extremely low birth weight infants born between the two groups (p > 0.05). There was also no significant difference in the proportion of babies who were macrosomic and in those who had a low 5-minute Apgar score <7. There were 866 (16%) neonatal admissions, 67/325 (21%) of these babies were born to women aged ≥40 years and 799/5,099 (16%) were born to their younger counterparts (p = 0.01). The commonest reason for admission was prematurity. While 60 babies died, there was no significant difference between both groups with 56 (1%) born to women 20 to 30 years and 4 (1%) born to women ≥40 years (p = 0.48). Conclusion Adverse outcomes noted for babies born to women ≥40 years were prematurity and the need for neonatal admission. However, no excess mortality was recorded. Key Points


2022 ◽  
Vol 40 ◽  
Author(s):  
Rafaelle Cristine Oliveira Cordeiro ◽  
Daniela Marques de Lima Mota Ferreira ◽  
Heloísio dos Reis ◽  
Vivian Mara Gonçalves de Oliveira Azevedo ◽  
Airan dos Santos Protázio ◽  
...  

ABSTRACT Objective: To assess the prevalence of hypothermia in the delivery room, at admission, and 2 to 3 hours after admission in the neonatal intensive care unit (NICU), factors associated and possible relationship with morbidity and mortality in preterm infants with very low birth weight (VLBW). Methods: Cross-sectional study with data collection based on a retrospective review of medical records and including infants born in 2016 and 2017, with birth weights <1500g, and gestational ages <34 weeks. Data about VLBW preterm infants, maternal data and temperature in the delivery room were analyzed. Hypothermia was considered when axillary temperature <36°C. For statistical analysis, the chi-square test or G test, canonical and Spearman correlation, and logistic regression were used. Results: 149 newborns (NB) were included in the study. The prevalence of hypothermia in delivery room, at admission to the NICU and 2 to 3 hours after admission was 25.8%, 41.5% and 40.2%, respectively. The temperature of NBs was directly proportional to gestational age (p<0.010), birth weight (p<0.010), and Apgar score (p<0.050). There was an inverse association with hypothermia in the delivery room and cesarean delivery (OR 0.25; p=0.016). Conclusions: Hypothermia was a prevalent problem in the studied population. The neonatal temperature was directly proportional to gestational age, birth weight and Apgar score. Hypothermia was associated with maternal factors, such as cesarean delivery. It is necessary to implement and improve strategies for its prevention.


2019 ◽  
Author(s):  
Yong-hui Yu ◽  
Li Wang ◽  
Xiao-yu Dong ◽  
Wen Li ◽  
Lei Huang ◽  
...  

Abstract Background Neonatal hypothermia, defined as a temperature < 36.5°C, is a major contributor to neonatal mortality and morbidity. Hypothermia in preterm infants remains a challenge in the neonatal intensive care unit (NICU) for many reasons.Objective To investigate the incidence of admission hypothermia (AH) in very low-birth weight (VLBW) infants in multiple NICUs in Shandong Province, China, and to provide clinical evidence for the implementation of quality improvement practices to reduce the incidence of AH in NICU.Methods This retrospective, observational study was carried out over a period of 12 months, from January 1, 2018 to December 31, 2018. The correlations between hypothermia preventive measures and the incidence of AH were analysed by descriptive statistical methods and a Spearman analysis. The associations between AH and maternal and neonatal variables were tested with bivariate analyses, followed by stepwise logistic regression. P <0.05 was considered statistically significant.Results A total of 1639 in-born infants who were born at a weight less than 1500 g were enrolled in the study on their day of birth. Among them, 1295 VLBW infants fulfilled the inclusion criteria. The incidence of AH was 87.9% in VLBW infants among the 28 NICUs. We investigated whether team training and education, such as monthly chart reporting on hypothermia in preterm infants on admission to the NICU, which was associated with 10.7% of all the cases, could decrease the rate of AH. Indeed, transport with a heated transport incubator was associated with 9.3% of the cases. here was a negative correlation between the incidence of AH and the number of quality improvement measures implemented to prevent hypothermia (r= -0.242, p <0.05). A low birth weight, intubation in the delivery room , and a low 5-min Apgar score were significantly associated with AH. Conclusion: The incidence of AH was high. There was a negative correlation between the incidence of AH and the number of quality improvement measures implemented to prevent hypothermia. It is important to monitor for AH in newborns who have a low birth weight, who have a low Apgar score at 5 min and who require intubation in the delivery room.


2014 ◽  
Vol 6 (1) ◽  
pp. 67-70
Author(s):  
Krishna Kumar Sahu ◽  
MZ Idris ◽  
Monika Agarwal ◽  
SK Singh ◽  
MK Manar

Background: Nutritional deficiency during pregnancy in rural India is common. The nutritional requirements during pregnancy are increased and on the other hand the dietary intake decreases because of symptoms related to pregnancy. This adversely affects the weight of newborn. In developing countries low birth weight is major problem. So this study concern to determine the nutritional status of pregnant women and its effect on birth weight of newborn. Methods: A cross section descriptive study was conducted from Oct 2011 to May 2012 at Sarojni Nagar PHC, Lucknow, Uttar Pradesh over 323 pregnant women. They were interviewed regarding their dietary intake (on the basis of 24 hours recall method) during pregnancy. Of these 323 pregnant women, 291 could be followed up and amongst these 287 pregnant women delivered a live baby. The birth weight was measured immediate after birth. Results: In this study mean energy, protein, iron and calcium intake during pregnancy were 2013.3 ± 327.6 cal/day, 57.8 ± 11.4 gm/day, 30.15 ± 5.57 mg/day and 910.7 ± 210.4 mg/day respectively, whereas the mean intake of vitamin A, thiamine, riboflavin, niacin, vitamin C and folic acid were 608.4±161.2 μg, 1.2±0.2mg, 1.6±0.2mg, 11.9±2.1mg, 113.3 ±2.1mg and 196.2±38.4μg respectively. Nutritional deficiency during pregnancy was positively related with low birth weight. Conclusion: In the rural setup of India majority of the pregnant women were having inadequate dietary intake. Hence, policies related to maternal nutrition should be made so as to decrease the prevalence of low birth weight. DOI: http://dx.doi.org/10.3126/ajms.v6i1.9473 Asian Journal of Medical Sciences Vol.6(1) 2015 67-70


2008 ◽  
Vol 84 (8) ◽  
pp. 533-538 ◽  
Author(s):  
Pen-Hua Su ◽  
Shu-Li Wang ◽  
Jia-Yuh Chen ◽  
Jui-Ming Hu ◽  
Hua-Pin Chang ◽  
...  

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