Fetal and Maternal Outcome Asymptomatic vs. Symptomatic Covid Positive Pregnant Women

2021 ◽  
Vol 15 (10) ◽  
pp. 3423-3425
Author(s):  
Amna Najam ◽  
Samreen Fakeer Muhammad ◽  
Samia Saifullah ◽  
Maryam Shoaib ◽  
Maria Anwar
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
Cesarean Section ◽  
Pregnant Women ◽  
Apgar Score ◽  
Adverse Outcomes ◽  
Maternal Outcomes ◽  
Group A ◽  
Nicu Admission ◽  
Group B

Objective: The aim of this study is to compare the fetal and maternal outcomes in between asymptomatic and symptomatic COVID positive pregnant women. Study Design: Retrospective cohort study Place and Duration: The study was conducted at Gynae and Obs department of Sandeman Provincial Hospital, Quetta for duration of six months from November 2020 to April 2021. Methods: One hundred and ten pregnant women with ages 18-45 years had corona virus disease were presented. Informed written consent was taken from all patients for detailed demographics. COVID -19 was diagnosed by PCR. 55 patients had symptoms of coronavirus were included in group A and 55 patients did not show symptoms were included in group B. Frequency of pre-eclampsia, gestational diabetes mellitus and post-partum haemorrhage were calculated. Maternal adverse outcomes (cesarean section, instrumental delivery, induction of labor and prolong labor, hypertensive disorder) were calculated among both groups. Fetal outcomes perinatal mortality, Low birth weight, Low Apgar score and NICU admission were observed. SPSS 20.0 version was used to analyze all data. Results: Mean age of the patients in group A was 28.47±3.18 years with mean BMI 24.03±5.24 Kg/m2 and in group B mean age was 27.99±4.17 years with mean BMI 24.44±6.41 Kg/m2. Maternal outcomes (cesarean section, instrumental delivery, induction of labor and prolong labor,) in symptomatic group were significantly higher than that of asymptomatic group. Fetal outcomes, perinatal mortality in group A 9 (16.4%) and in group B was 5 (9.1%), low birth weight in group A was among 21 (38.2%) and in group B was 10 (18.2%), low apgar score in group A was 11 (20%) and in group B was 8 (14.4%), 15 (27.3%) in group A went to NICU admission and 3 (5.5%) patient in group II admitted to NICU. Conclusion: In this study we concluded that adverse outcomes among symptomatic COVID pregnant women were higher than that of asymptomatic coronavirus pregnant women in terms maternal and perinatal outcomes. Keywords: Pregnant women, Coronavirus, Symptomatic, Asymptomatic, Adverse Outcomes

scholarly journals Comparison of Maternal and Fetal Outcomes in Pregnancies with Preterm Premature Rupture of Membrane (PPROM) Terminating in 34th or 36th Gestational Weeks: A Clinical Trial

2017 ◽  
Vol 5 (2) ◽  
pp. 3
Author(s):  
Shamsi Abbasalizadeh ◽  
Rana Bagherifard ◽  
Farshad Mahdavi ◽  
Fatemeh Abbasaizadeh ◽  
Shiva Raouf
Keyword(s):  
Birth Weight ◽  
Pregnant Women ◽  
Pregnancy Termination ◽  
Neonatal Outcomes ◽  
Birth Complications ◽  
Significant Difference ◽  
Group A ◽  
Maternal And Neonatal Outcomes ◽  
Nicu Admission ◽  
Group B

present  study,  we aimed at studying maternal  and  neonatal  outcomes  in  patients with terminated pregnancy in 34th  and  36th  gestational  weeks. Materials and methods: 40 pregnant women, with PPROM who underwent pregnancy termination at 34 group (A) or 36 group (B) gestational weeks, were included to be evaluated and compared for maternal and neonatal outcomes. Type of delivery, birth complications, chorioamnoionitis, endometritis, sepsis, maternal mortality, infant gender, birth weight, Apgar scores, respiratory distress syndrome, Meconium-stained amniotic fluid, NICU admission, abruption, umbilical cord prolapse, maternal and neonatal outcomes were compared between the two groups.  Results: There was no statistically significant difference between the two groups regarding maternal age, level of education, or gravity. The percentage of cases with birth weight between 1500 and 2500 g was significantly higher in group A P<0.001). Frequency of NICU admission in group A was significantly more than group B (P<0.001). In conclusion: Termination of pregnancy at 36 weeks compared to 34 weeks in pregnant women with PPROM is preferred in terms of neonatal outcomes and it is recommended; also, there might be no preference in terms of  maternal outcomes. 

Advanced Maternal Age and Adverse Maternal and Neonatal Outcomes in Pregnant Women

2020 ◽  
Vol 16 ◽  
Author(s):  
Reza Omani-Samani ◽  
Saman Maroufizadeh ◽  
Nafise Saedi ◽  
Nasim Shokouhi ◽  
Arezoo Esmailzadeh ◽  
...  
Keyword(s):  
Birth Weight ◽  
Preterm Birth ◽  
Low Birth Weight ◽  
Cesarean Section ◽  
Pregnant Women ◽  
Maternal Age ◽  
Unwanted Pregnancy ◽  
Advanced Maternal Age ◽  
Neonatal Outcomes ◽  
Maternal And Neonatal Outcomes

Background: Advanced maternal age is an important predictor for maternal and neonatal outcomes such as maternal mortality, low birth weight, stillbirth, preterm birth, cesarean section and preeclampsia. Objective: To determine the association of advanced maternal age and adverse maternal and neonatal outcomes in Iranian pregnant women. Methods: In this hospital-based cross-sectional study, 5117 pregnant women from 103 hospitals in Tehran, Iran, were participated in the study in 2015. The required data were gathered from hospitals which equipped to the department of obstetrics and gynecology. Advanced maternal age was considered as an independent variable and unwanted pregnancy, preeclampsia, preterm birth, cesarean section and low birth weight were considered as interested outcomes. Results: In our study, the prevalence of advanced maternal age was 12.08%. Advanced maternal age was significantly associated with higher risk of unwanted pregnancy (OR: 1.39, 95% CI: 1.12-1.73), preterm birth (OR: 1.75, 95% CI: 1.28- 2.39) and cesarean section (OR: 1.34, 95% CI: 1.03-1.74). In our study, there was no significant relationship between advanced maternal age and preeclampsia but this relationship could be clinically important (OR: 1.48, 95% CI: 0.99-2.20, P=0.052), and there is no significant relationship between advanced maternal age and low birth weight (OR: 1.08, 95% CI: 0.67-1.74, P=0.736). Conclusion: Advanced maternal age is associated with higher risk of unintended pregnancy, preterm birth and cesarean section but our findings did not support advanced maternal age as a risk factor associated with low birth weight.

HPV Prevalence and its Association with Perinatal Outcomes among Singleton Mothers: Analysis of Pregnancy Risk Assessment and Monitoring System (PRAMS) Data, 2004-2011

2019 ◽  
Vol 15 (2) ◽  
pp. 143-149 ◽  
Author(s):  
Harpriya Kaur ◽  
Delf Schmidt-Grimminger ◽  
Baojiang Chen ◽  
K.M. Monirul Islam ◽  
Steven W. Remmenga ◽  
...  
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
Pregnant Women ◽  
Monitoring System ◽  
Large Population ◽  
Perinatal Outcomes ◽  
Hpv Infection ◽  
Adverse Outcomes ◽  
P Value ◽  
Pregnancy Risk

Background: Pregnancy may increase the risk of Human Papillomavirus (HPV) infection because of pregnancy induced immune suppression. The objective of this study was to use a large population-based dataset to estimate the prevalence of HPV infection and its association with adverse outcomes among pregnant women. Methods: We analyzed Pregnancy Risk Monitoring System data from 2004-2011 (N=26,085) to estimate the self-reported HPV infection. Survey logistic procedures were used to examine the relationship between HPV infection and adverse perinatal outcomes. Results: Approximately 1.4% of women were estimated to have HPV infection during their pregnancy. The prevalence of adverse outcomes in this sample was preterm birth (8.4%), preeclampsia (7.5%), low birth weight (6.3%) and premature rupture of membranes (2.8%). Compared to women without HPV infection, HPV infection positive women were much more likely to have had other infections such as chlamydia (9.23% vs. 2.12%, p-value <.0001), Group B Strep (21.7% vs. 10.04%, p-value <.0001), and herpes (7.17% vs. 1.07%, p-value <.0001). After adjusting for other risk factors including other infections, HPV infection was significantly associated with low birth weight (OR: 1.94, 95% CI: 1.14-3.30). Conclusion: The study indicated a potential association between HPV infection and low birth weight. Because pregnant women with HPV infection are at higher risk of other infections, future research may focus on the roles of co-infection in the development of adverse perinatal effects.

scholarly journals Comparison of Maternal and Perinatal Outcome in Pregnant Women with Hypothyroidism Diagnosed before Conception with Hypothyroidism Diagnosed during Pregnancy

2014 ◽  
Vol 2 (2) ◽  
pp. 21-27
Author(s):  
P Basnet ◽  
N Aggrawal ◽  
V Suri ◽  
P Dutta ◽  
K Mukhopadhyay
Keyword(s):  
Birth Weight ◽  
Pregnant Women ◽  
Thyroid Function ◽  
Early Pregnancy ◽  
Perinatal Outcome ◽  
Fetal Outcome ◽  
Endocrine Disorder ◽  
Fetal Birth Weight ◽  
Group A ◽  
Group B

BACKGROUND: Thyroid disorder is one of commonest endocrine disorder in women and hence constitutes a common endocrine disorder complicating pregnancy. Diagnosing and treating hypothyroidism preconceptionally and during early pregnancy appears to be a useful strategy to improve maternal and fetal outcome. OBJECTIVE: To compare the maternal and perinatal outcome in pregnant women with hypothyroidism diagnosed preconceptionally with hypothyroidism diagnosed during pregnancy. METHODS: A prospective study. One hundred pregnant women with hypothyroidism at less than 20 weeks Period of Gestation (POG) were recruited for the study and grouped into two groups: Group A-hypothyroidism diagnosed and on treatment before conception, Group B-hypothyroidism diagnosed and started on treatment during pregnancy. Both groups were intensively monitored during pregnancy with serial Thyroid Function Test (TFT) and thyroxine replacement doses were adjusted accordingly. Various maternal, perinatal and fetal outcome measures were studied in both groups prospectively till delivery. RESULTS: The maternal and fetal complications were comparable in the two groups, however the fetal birth weight was significantly higher in Group A versus Group B (2.89±0.485kg vs. 2.70±0.453kg; p=0.039). All the new born babies had normal thyroid function. CONCLUSION: Hypothyroidism diagnosed preconceptionally or during early pregnancy and treated appropriately has beneficial effect on fetal birth weight, and hence the total pregnancy outcome. Screening for thyroid dysfunction should be judiciously performed in all high risk women prior to a planned conception or during their first antenatal visit. DOI: http://dx.doi.org/10.3126/jucms.v2i2.11170   Journal of Universal College of Medical Sciences (2014) Vol.2(2): 21-27

scholarly journals LABOR AT TERM

2016 ◽  
Vol 23 (11) ◽  
pp. 1354-1357
Author(s):  
Quddsia Tanveer ◽  
Anees Fatima ◽  
Ummara Maqsood Sana
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
Cesarean Section ◽  
Apgar Score ◽  
Postpartum Hemorrhage ◽  
Neonatal Morbidity ◽  
Medical Illness ◽  
Maternal Complications ◽  
Cross Sectional ◽  
Nulliparous Women

Objectives: To compare the obstetric outcome between primigravida andmultigravida presenting in labor at term. Study Design: Cross sectional study. Period: Sixmonths from Jan 2013 to Jun 2013. Setting: Obs/Gynae unit III, Jinnah hospital, Lahore.Patients and methods: 800 patients were included in the study which comprised 400of primigravida and 400 of multigravida. Patients having single, alive fetus with cephalicpresentation at 37-41 weeks were included in the study. Those having recurrent miscarriages,parity >5, antepartum hemorrhage, previous uterine scars and significant medical illness wereexcluded from the study. The data was collected on specially designed proforma. Observationsmode of delivery including the indication of cesarean section or instrumental vaginal deliveryif applicable. Maternal complications such as postpartum hemorrhage along with its cause,retained placenta and uterine inversion were also recorded. Fetal and neonatal observationsincluded CTG abnormalities, oligohydramnios, low birth weight, macrosomia, Apgar score < 7at 5minutes, NICU admission, fresh still birth and early neonatal death. Results: Mean age was25.57+ 3.46 years in primigravida women while it was 25.75 + 3.44 years in multigravida group.CTG abnormalities (15.5% VS 4.25%), instrumental deliveries (9.75% VS 1%), cesarean section(15.25% VS 1%) and postpartum hemorrhage (5.7% VS 1.75%) were commoner in primigravidawomen. In addition, NICU admissions, low birth weight babies and a low Apgar score at5-minute were also commoner in primigravida women. Conclusion: Nulliparous women areat greater risk of labor abnormalities, fetal distress, instrumental deliveries, cesarean section,postpartum hemorrhage and neonatal morbidity. These adverse factors should therefore belooked for and treated well in time.

scholarly journals Clinical evaluation of anesthesia for high-risk cesarean section at a tertiary medical center: retrospective study for 8 years (2009–2016)

2019 ◽  
Vol 47 (9) ◽  
pp. 4365-4373
Author(s):  
HW Kang ◽  
WY Kim ◽  
SJ Jin ◽  
YH Kim ◽  
TJ Min ◽  
...  
Keyword(s):  
Risk Factors ◽  
Birth Weight ◽  
High Risk ◽  
Gestational Age ◽  
Perioperative Outcomes ◽  
Apgar Scores ◽  
Maternal Risk ◽  
Group A ◽  
Nicu Admission ◽  
Group B

Objective The number of high-risk pregnancies is increasing in tertiary medical centers. Therefore, we investigated perioperative outcomes based on risk factors to ascertain proper maternal and neonatal management. Methods We reviewed the medical records of patients receiving cesarean sections over an 8-year period. Clinical parameters for anesthesia and the neonatal outcome were compared among high-risk groups after subdivision by the number of clinical risk factors. The groups were as follows: group A (one risk factor), group B (two risk factors), and group C (three or more risk factors). Results Patient age, estimated blood loss (EBL), and volume of transfused red blood cell (RBC) were higher in group B than group A. Birth weight, 1- and 5-minute Apgar scores, and gestational age were lower while the frequency of neonatal intensive care unit (NICU) admission was higher in group B than group A. Group C patients were significantly older than group A or B patients. Birth weight, 1- and 5-minute Apgar scores and gestational age were significantly lower while frequency of NICU admission was higher in group C than group A and B. Conclusion The number of maternal risk factors was positively associated with adverse outcomes in the neonates.

THE STUDY OF MATERNAL AND FETAL OUTCOME IN PREGNANT WOMEN WITH THYROID DISORDER: A PROSPECTIVE STUDY IN INDORE REGION

2021 ◽  
pp. 69-71
Author(s):  
Preeti Gupta ◽  
Manila Jain ◽  
Nand K Gupta ◽  
Umesh K Gupta
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
Adverse Effects ◽  
Pregnant Women ◽  
Thyroid Dysfunction ◽  
Thyroid Stimulating Hormone ◽  
Thyroid Disorder ◽  
Cross Sectional ◽  
Foetal Outcome ◽  
Nicu Admission

BACKGROUND: Thyroid disorder is very common disorders in pregnancy. It is well established that overt and subclinical thyroid dysfunction has adverse effects on mother and the foetus like miscarriages, preterm delivery, preeclampsia, eclampsia, polyhydramnios, placental abruption, postpartum haemorrhage, low birth weight, fetal distress, NICU admission. With this background, we are conducting a study to know the effect of thyroid disorder on pregnancy and its maternal and foetal outcome. METHODS: The present study was carried out in Index Medical College, Indore, MP, India in Department of physiology in collaboration with Department of Obstetrics & Gynecology. It is a prospective random cross-sectional study done over 180 pregnant women (90 pregnant women with thyroid disorder and 90 with normal thyroid) which includes known cases of thyroid disorder. Serum thyroid stimulating hormone (TSH), fT3, and fT4 tests were apart from the routine blood sample investigations as per FOGSI-ICOG good clinical practice recommendation. Patients are followed up till delivery, and their obstetrics and perinatal outcomes are noted. RESULTS: In our study prevalence of thyroid dysfunction was 10.4%. Out of these 90 patients with thyroid dysfunction, complications associated were pre-eclampsia (14.4%), abortions (13.3%), maternal anaemia (11.1%), preterm labour (7.8%), still birth (5.6%), abruption placenta (4.4%). Out of 90 patients with thyroid dysfunction, foetal complications seen were low birth weight (22.2%), NICU admission (15.6%), hyperbilirubinemia (14.4%) and foetal distress (5.6%). CONCLUSIONS: Our result demonstrated that the thyroid disorders during pregnancy have adverse effects on maternal and foetal outcome emphasizing the importance of routine antenatal thyroid screening.

Efficacy of probiotics to prevent necrotizing enterocolitis in low birth weight preterm neonates.

2021 ◽  
Vol 28 (03) ◽  
pp. 328-332
Author(s):  
Shagufta Niazi ◽  
Farrukh Saeed ◽  
Shahla Tariq ◽  
Muhammad Azhar Farooq ◽  
Sanaullah Khan ◽  
...  
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
Necrotizing Enterocolitis ◽  
Controlled Trial ◽  
Study Groups ◽  
Preterm Neonates ◽  
Randomized Controlled ◽  
Group A ◽  
Group B ◽  
Trial Setting

Objective: To compare the efficacy of probiotics in prevention of necrotizing enterocolitis (NEC) among low birth weight (LBW) preterm neonates. Study Design: Randomized controlled trial. Setting: Department of Pediatric Medicine, Unit-II, Services Hospital, Lahore. Period: September 2019 to February 2020. Material and Methods: A total of 260 LBW preterm neonates were enrolled. All the neonates were allocated to 2 groups with equal number of cases (130 in each group). Group-A was given probiotics whereas placebo was administered in Group-B. All the cases were admitted and follow ups were made up until 7th day. Occurrence of NEC was recorded among both groups. Results: Out of a total of 260 LBW preterm neonates, 142 (54.6%) were male and118 (45.4%) female. Overall, mean age was noted to be 1.48+0.50 days. Table-I shows that there was no statistical difference among neonates of both study groups in terms of age, gestational age and birth weight (p>0.05). Five (3.8%) neonates in Group-A and 14 (10.8%) in Group-B were found to have NEC. Efficacy of treatment in Group-A was significantly higher in comparison to Group-B. Conclusion: Probiotics are effective in the prevention of NEC in preterm LBW neonates. Prophylactic usage of probiotics among preterm neonates is noted to be helpful in avoiding development of NEC.

scholarly journals Transient Hypothyroxinaemia in Full Term Low Birth Weight Neonates

1970 ◽  
Vol 6 (1) ◽  
pp. 8-11
Author(s):  
Z Parveen ◽  
N Begum ◽  
MM Hossain
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
Low Birthweight ◽  
Full Term ◽  
Military Hospital ◽  
Control Group ◽  
Base Line ◽  
Group A ◽  
The Mean ◽  
Group B

This prospective study was done in Combined Military Hospital, Dhaka from July 2002 to June 2003 todocument the postnatal changes of thyroid hormones in full term low birth weight (LBW) neonates. Theparameters were- serum TT4 (total thyroxin), TT3 (total triiodothyronine), FT4 (free thyroxin) and TSH(thyroid stimulating hormone). Twenty seven healthy full term neonates formed the control group (group A)who were studied on day 5 to observe the base line data. Study group (group B) consisted of 27 low birthweight (LBW) neonates. They were studied twice on day 5 (B1) and day 45 (B2). The mean ± SD gestational agewas 38.41±0.93 and 38.63±1.08 weeks in group A and B respectively. The mean ± SD birth weight were3.41±0.55 and 2.11±0.33 kg in group A and B respectively and the difference was statistically significant (p<0.0001). All neonates of group A had normal serum levels of TT4, TT3, FT4 and TSH on day 5 but in LBW fullterm neonates though FT4 level remained within normal range, 48% neonates of group B had significantlydecreased levels of TT4, TT3 and TSH (p<0.001) but on day 45 all of these hormone levels were significantlyincreased (p<0.001) and attained normal values. This study showed that 48% LBW neonates had transienthypothyroxinaemia on day 5 which was corrected spontaneously by day 45.Key words: Hypothyroxinaemia; Low birth weight (LBW).DOI: 10.3329/jafmc.v6i1.5984Journal of Armed Forces Medical College, Bangladesh Vol.6(1) 2010 p.8-11

scholarly journals EFFECTIVENESS OF POLYETHYLENE SKIN WRAP IN PREVENTION OF HYPOTHERMIA IN PRETERM AND LOW BIRTH WEIGHT NEONATES

2021 ◽  
Vol 71 (3) ◽  
pp. 810-13
Author(s):  
Goher Ali Khan ◽  
Usman Riaz ◽  
Sara Iqbal ◽  
Tariq Aziz Qureshi ◽  
Hina Kanwal Shafaat
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
Neonatal Intensive Care ◽  
Intervention Group ◽  
Military Hospital ◽  
Control Group ◽  
Quasi Experimental ◽  
Group A ◽  
Group B ◽  
Neonatal Hypothermia

Objective: To establish the effectiveness of polyethylene skin wrap in prevention of neonatal hypothermia in preterm and low birth weight neonates. Study Design: Quasi-experimental study. Place and Duration of Study: Department of Pediatrics, Combined Military Hospital Quetta, from May 2015 to Apr 2017. Methodology: A total of 176 neonates were enrolled according to the inclusion and exclusion criteria, through non-probability consecutive sampling. Eighty eight newborns were randomly distributed to each of group “A” and “B” by lottery method. The intervention group “A” infants were wrapped in a polyethylene skin wrap from shoulders down while the control group “B” newborns were wrapped with conventional blankets. After shifting to neonatal intensive care unit, axillary temperatures were recorded with similar pediatric digital thermometers upon admission and after one hour and two hours following admission in the two groups. Results: The mean temperatures measured at one hour and two hours after admission showed significant statistical improvements in the intervention group as compared to the control group (<0.05). Conclusion: The use of polyethylene skin wrap in preterm and low birth weight neonates potentially offers a useful intervenetion in prevention of neonatal hypothermia.

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