scholarly journals Effectiveness of misoprostol for induction of first and early second trimester spontaneous miscarriages in parous women

2018 ◽  
Vol 7 (11) ◽  
pp. 4512
Author(s):  
Tamima Al-Dughaishi ◽  
Amjad Hamed Al-Haddabi ◽  
Mussab Mussab Mubarak Hamed Al-Jabri ◽  
Vaidyanathan Gowri
Keyword(s):  
Success Rate ◽  
First Trimester ◽  
University Hospital ◽  
Second Trimester ◽  
Sultan Qaboos University ◽  
Dilatation And Curettage ◽  
Dilation And Curettage ◽  
Medical Termination ◽  
Surgical Evacuation ◽  
Incomplete Miscarriage

Background: Medical termination of missed miscarriage and incomplete miscarriage with misoprostol, are an alternative to surgical evacuation (dilatation and curettage). This study aimed to evaluate the effectiveness of misoprostol in highly parous woman for incomplete and missed miscarriage.Methods: This was a retrospective study was conducted in two different time lines (2010 and 2014). All patients admitted to the Sultan Qaboos University hospital, Muscat, Oman, for the management of first-trimester miscarriages (missed and incomplete types) during the study period were included. Some women were moved to dilation and curettage even after misoprostol. The effect of gravidity and parity on those women in whom misoprostol was not effective was studied.Results: The overall success rate of misoprostol for the management was 62.14% in 2010 and 53.8% 2014. In nulliparous woman the success rate of misoprostol was slightly higher than parous women. There was no apparent effect of gravidity and parity of ≥ 5 or ≥ 5 on the success of misoprostol.Conclusions: Misoprostol reduced the rate of surgical evacuation among the study subjects. In highly parous and multigravid women (≥ para 5 and gravida ≥5) the success was not significantly different compared to less parous women.

scholarly journals Low dose Mifepristone (100 mg) for medical termination of pregnancy

2011 ◽  
Vol 3 (1) ◽  
Author(s):  
Shikha Seth ◽  
Arun Nagrath ◽  
Neeru Goel
Keyword(s):  
Side Effects ◽  
Success Rate ◽  
Low Dose ◽  
Medical Abortion ◽  
First Trimester ◽  
Effective Regimen ◽  
Minimal Dose ◽  
Medical Termination ◽  
Gestation Age ◽  
Post Abortion

Background: Abortion is the most common entity in the practice of obstetrics and gynaecology. Different methods and modes have been opted for until now to find an effective regimen with the least complications. We have tried the minimal dose (100 mg) of Mifepristone (PO) instead of the presently recommended 200 mg for medical abortion in early first trimester cases. Objectives: The objective of the study was to determine the efficacy of low dose (100 mg) Mifepristone for medical termination of early pregnancy with oral Misoprostol 800 μg, 24 hours later.Design: A prospective analytical study was conducted on a population of 82 early-pregnant patients who have requested medical abortions.Method: Pregnant women of less than 56 days gestation age from their last menstrual period, requesting medical abortion were selected over a period of 14 months from January 2007 to March 2008. They were given 100 mg Mifepristone orally on Day-1, followed by 800 μg Misoprostol orally 24 hours later on Day-2, keeping the patient in the ward for at least 6 hours. Abortion interval, success rate, post-abortion bleeding and side-effects were noted. Success was defined as complete uterine evacuation without the need for surgical intervention.Results: The total success rate of this minimal dose Mifepristone regimen was 96.25%. Pain and nausea were the predominant side-effects noted. In total 72 (90%) women had completely aborted within 5 hours of taking Misoprostol. Three (3.75%) women only required suction aspiration, hence termed as failed medical abortion. The abortion interval increased with the gestation age. All three failures were of the more-than-42-day gestational age group. The overall mean abortion interval was 4.68 ± 5.32 hours.Conclusion: Mifepristone 100 mg, followed 24 hours later by Misoprostol 800 μg orally, is a safe and effective regimen for medical abortion.

scholarly journals Extracorporeal Shock-wave Lithotripsy Success Rate and Complications: Initial Experience at Sultan Qaboos University Hospital

2013 ◽  
Vol 28 (4) ◽  
pp. 255-259 ◽  
Author(s):  
Mohammed S. Al-Marhoon ◽  
Omar Shareef ◽  
Ismail S. Al-Habsi ◽  
Ataalrahman S. Al Balushi ◽  
Josephkunju Mathew ◽  
...  
Keyword(s):  
Shock Wave ◽  
Success Rate ◽  
Extracorporeal Shock Wave Lithotripsy ◽  
Shock Wave Lithotripsy ◽  
University Hospital ◽  
Initial Experience ◽  
Sultan Qaboos University ◽  
Extracorporeal Shock Wave

scholarly journals A retrospective study of efficacy and cost efficiency of medical vs. surgical management of abortions in first trimester

2021 ◽  
Vol 10 (9) ◽  
pp. 3429
Author(s):  
Meetangi Agarwal ◽  
Sailatha Ramanujam ◽  
Anuradha C. Ramachandran
Keyword(s):  
Success Rate ◽  
Pregnancy Termination ◽  
Transvaginal Ultrasound ◽  
Cost Effective ◽  
Medical Abortion ◽  
First Trimester ◽  
Observational Research ◽  
Medical Termination ◽  
Significant Difference

Background: The aim of the study was to assess and comparatively evaluate the efficacy of different methods of first trimester abortions (medical, surgical) in terms of its safety, cost and effectiveness.Methods: We present a retrospective observational research study done at Chettinad hospital and research institute, Kelambakkam Chennai which included a total of 70 patients of first trimester abortions, in the period from June 2019 to June 2020. 55 patients were offered medical treatment (MTOP) and were followed up with a repeat scan after 2 weeks. In cases of failed medical abortion patient underwent curettage. Though, in some cases after an attempt at medical abortion, if the products didn’t expel at all within 48 hours, dilatation and evacuation was offered. Transvaginal ultrasound was performed to confirm the success of the treatment. In 15 cases who presented with incomplete abortion, surgical treatment (STOP) was offered. The outcomes considered were successful complete abortions, failed medical abortions, side effects and complications including blood transfusion.Results: The baseline characteristics of women were similar in both the groups like mean age, parity, history of previous termination of pregnancy (TOP). The success rate in MTOP was 67.2% and in STOP 100%.The amount of bleeding experienced was moderate to heavy in MTOP and minimal to moderate in STOP.37 women who underwent only medical termination who returned for the 2-week follow-up, the rate of complete pregnancy termination was 94% and for the remaining 2 women surgical intervention was required. In the surgical group, at the 2-week follow up, no woman underwent a repeat vacuum aspiration with an efficacy of 100%. No significant difference was found in the mean total cost for the medical and surgical groups after adding the subsequent costs (including additional manual vacuum evacuation).Conclusions: Medical termination of abortion should be preferred over surgical termination as it is safer, cost effective, with fewer complications and high success rate. 

scholarly journals PREDICTORS OF POOR PROGNOSIS IN PREGNANT WOMEN WITH COVID-19: A PROSPECTIVE COHORT STUDY IN THE MATERNITY MOTHER AND CHILD UNIVERSITY HOSPITAL OF CASABLANCA MOROCCO

2021 ◽  
Vol 9 (10) ◽  
pp. 735-741
Author(s):  
Lamrissi A. ◽  
◽  
Midyani H. ◽  
Khalloufi C. ◽  
Jalal M. ◽  
...  
Keyword(s):  
Pregnant Women ◽  
Death Rate ◽  
Poor Prognosis ◽  
First Trimester ◽  
University Hospital ◽  
Maternity Unit ◽  
Second Trimester ◽  
Third Trimester ◽  
High Prevalence ◽  
Mother And Child

Objective: We aim to study the clinicalcharacteristics, the evolution of COVID-19 on pregnant women and survival factors. Study design: Its a prospective cohortstudy in a large tertiary maternity unit within the Mother and Child University Hospital Ibn Rochd of Casablanca with an average annual birth of over 6950 births. We prospectively collected and analyzed data for a cohort of 40 pregnant patients tested positive for COVID-19 between January 2020 and December 2020 inclusive to assess the effect of COVID-19 on pregnancy. Results: Forty pregnant patients testedpositive for COVID-19, 36 patients gave birth and 4 patients died pregnant. The severity of the symptoms ranged from mild in 20/40 (50%) of the patients, moderate in 7/40 (17,5%), and severe in 13/40 (32,5%). Thirteen of our patients were admitted to invasive care units, six were in their third trimester, and seven in their second trimester nine were intubated and ventilated prior to delivery and three of them required Extracorporeal membrane oxygenation. Among these patients intubated only two survived. Most common comorbidities were gestational diabetes 4/40 (10 %), asthma 4/40 (10 %), preeclampsia 7/40 (17,5%). Of the 40 pregnant patients 31 (77,5%) were in their third trimester, 8 (20%) women in their second trimester, and one in her first trimester. Of the 36 patients who delivered, 12/36 (33,3 %) were preterm delivered by elective C-sections. The death rate was 17,5% (7/40). Conclusion: COVID-19 is associated with high prevalence of preterm birth, caesarean section, and a high mortality rate.

Factors Influencing the Success Rate of Intrauterine Insemination: ARetrospective Study in Sultan Qaboos University Hospital

2017 ◽  
Vol 06 (05) ◽  
Author(s):  
Bushra Ahmed ◽  
Gowri Vaidyanathan ◽  
Silja Arumughan Pillai ◽  
Jokha AlSabti ◽  
Maha Al Khaduri ◽  
...  
Keyword(s):  
Success Rate ◽  
Intrauterine Insemination ◽  
University Hospital ◽  
Sultan Qaboos University ◽  
Factors Influencing

Gemeprost for second-trimester termination of pregnancy

1989 ◽  
Vol 27 (26) ◽  
pp. 103-103
Keyword(s):  
First Trimester ◽  
Termination Of Pregnancy ◽  
Prostaglandin E ◽  
Second Trimester ◽  
Vacuum Aspiration ◽  
First Trimester Pregnancy ◽  
Trimester Pregnancy ◽  
Vaginal Pessary ◽  
Medical Termination ◽  
Endogenous Prostaglandins

During labour endogenous prostaglandins are involved in the process of softening the cervix. Gemeprost, an analogue of prostaglandin E1, is used as a vaginal pessary (Cervagem - May & Baker) to soften and dilate the cervix before vacuum aspiration of first-trimester pregnancy.1 It can now also be used for medical termination of pregnancy in the mid-trimester.

Abortion

2019 ◽  
Author(s):  
Nisha Verma ◽  
Siripanth Nippita
Keyword(s):  
Pregnancy Termination ◽  
Healthcare Providers ◽  
Medical Abortion ◽  
First Trimester ◽  
The United States ◽  
Decision Making Process ◽  
Basic Information ◽  
Second Trimester ◽  
Dilation And Curettage ◽  
Cervical Preparation

Individuals may have a variety of reasons to end a pregnancy. Healthcare providers should provide support during the decision-making process and should be able to give patients basic information about their options depending on gestational age. In the United States, clinicians can offer first-trimester medical abortion with mifepristone and misoprostol up to 10 weeks’ gestation. Uterine aspiration or dilation and curettage are options throughout the first trimester. Options in the second trimester include induction abortion with medications, or a surgical procedure (dilation and evacuation) which may require cervical preparation at later gestational ages. Clinicians should assess the patient’s desire for fertility following an abortion and may offer contraception or preconception advice, as appropriate. This review contains 13 figures, 6 tables, and 61 references. Key Words: abortion, dilation and curettage, dilation and evacuation, mifepristone, misoprostol, pregnancy termination

Standardizing Second-Trimester Medical Termination: Effects on Clinical Outcomes

2018 ◽  
Vol 35 (08) ◽  
pp. 791-795
Author(s):  
Michelle Wyatt ◽  
Mary Tolcher
Keyword(s):  
Primary Outcome ◽  
Termination Of Pregnancy ◽  
Second Trimester ◽  
Medical Termination Of Pregnancy ◽  
Dilation And Curettage ◽  
Medical Termination ◽  
Significant Difference ◽  
Before And After ◽  
Baseline Characteristics ◽  
Secondary Outcomes

Objective The objective of this study was to evaluate length of induction and postdelivery complications before and after implementation of a standardized approach to second-trimester medical termination of pregnancy. Study Design This was a retrospective cohort study of all women undergoing medical termination of pregnancy between 130/7 and 266/7 weeks of gestation at a single, academic institution from July 1, 2012, through June 30, 2015. The primary outcome was the time from the start of induction of labor to delivery of the fetus. Postdelivery complications including the need for dilation and curettage (D&C), blood transfusion, and readmission to the hospital were secondary outcomes of interest. Results A total of 62 women met inclusion criteria; 38 before and 24 after the intervention. There were no differences in measured baseline characteristics (p > 0.05). There was a significant decrease in induction time after the intervention (12.3 compared with 8.6 hours, p = 0.031). There was no significant difference in rates of D&C or other measured complications (p > 0.05). Conclusion Implementation of a standardized clinical guideline for second-trimester medical termination was associated with a decrease in length of induction. There was no significant difference in need for D&C or postdelivery complications; however, we were underpowered for these secondary outcomes.

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