scholarly journals Correlation between obstetric outcome and amniotic fluid index (AFI) in preterm prelabour rupture of membranes (PPROM)

Author(s):  
Anusree Saraswathy ◽  
Jayshree V. Vaman ◽  
Mayadevi Brahmanandan ◽  
Nirmala C.

Background: The purpose was to determine whether AFI<5 cm after preterm premature rupture of the membranes (PPROM) is associated with an increased risk of maternal and perinatal morbidity.Methods: We performed a prospective case control study of 161 singleton pregnancies complicated by preterm prelabour rupture of the membranes (PPROM) in whom AFI was assessed. Patients were categorized in two groups on the basis of amniotic fluid index- AFI<5 cm or AFI ≥ 5 cm. Categorical data were tested for significance with the χ2 and Fisher exact tests. All 2-sided p values < 0.05 were considered significant.Results: Both groups were similar with respect to selected demographics, gestational age atrupture of the membranes, gestational age at the delivery, birth weight. Both groups were similar with respect to maternal chorio-amnionitis, abruption, mode of delivery, early onset neonatal sepsis and NICU stay. Patients with AFI<5 cm demonstrated greater frequency of C/S delivery for non-reassuring fetal tests.Conclusions: There is no significant difference between obstetric outcome in AFI<5 and AFI> 5 after PPROM between 24- and 37-weeks’ gestation.

2017 ◽  
Vol 23 (2) ◽  
Author(s):  
Natasha Bushra ◽  
Khaula Zeeshan ◽  
Sara Ejaz ◽  
Javeria Mushtaq ◽  
Khadija Waheed ◽  
...  

AbstractThe increased risk of caesarean section after induced labour is well documented. Rate of induction of labour has doubled in the past decade from 10 to 20%. Low Amniotic Fluid Index (AFI) as an isolated finding leads to increased obstetrical interventions but without any improvement in outcome.Objectives:  To determine the frequency of caesarean section due to failed induction in pregnancies at term with borderline AFI.Patients and Methods:  This cross-sectional study was conducted at Department of Obstetrics and Gynaecology, Unit-III, SIMS/Services Hospital, Lahore. The duration of study was one year from January, 2015 to December, 2015. A total of 150 patients were included in this study. AFI was measured by recent obstetric ultrasound. All patients with borderline AFI (5 – 8 cm) were included in the study. They were induced by glandin E2 gel. If induction of patients failed with two doses of glandin E2 gel, given vaginally 6 hours apart, patients were considered for cesarean section. The outcome measure was rate of caesarean section due to failed induction. All data were analyzed by SPSS version 20.Results:  Mean age of the patients was 30.34 ± 6.68 years. Mean gestational age was noted 38.34 ± 1.05 weeks. Out of 150 patients, 103 (68.7%) were para 1 – 3 and 47 patients (31.3%) were para 4 – 6. Caesarean section due to failed induction with borderline AFI was performed in 27 patients (18.0%). Stratification with regard to age, gestational age and parity was carried out and was found significant only for gestational age being > 39 weeks.Conclusion:  It is concluded that failed induction of labour at term in women with borderline AFI is not associated with increased risk of caesarean delivery.


2017 ◽  
Vol 13 (4) ◽  
pp. 401-405
Author(s):  
Rajiv Shah ◽  
Paban Sharma

Background & Objectives: The measurement of amniotic fluid volume (AFV) has been an important component of antenatal evaluation of fetal well being. The most commonly used methods are by amniotic fluid index technique (AFI) and single deepest pool method (SDVP). Both the methods employ ultrasound for AFV measurement. The objective of this study is to compare the usefulness of AFI and SDVP method in assessing amniotic fluid volume for predicting adverse perinatal outcome.Materials & Methods: This is a hospital based prospective comparative study. The patient whose amniotic fluid was measured by SDVP technique was study group and that by AFI was comparison group. Any case with high risk factor was excluded from the study. First case was decided by lottery and then alternately one case was kept in study group and the other in comparative group. If the women did not deliver within 1 week the measurements was retaken and the final values was used for analysis.AFI was estimated as described by Phelan and colleagues and SDVP as described by Manning. Data collection was started after the approval of Institution review board. This study was conducted at Patan Academy of Health Sciences. Duration of data collection was 3 months, Asadh –Bhadra, 2071.Results: A total of one hundred and fifty four cases which met the inclusion criteria were taken. Incidence of oligohydramnios by SDVP method was 10.4 % by SDVP technique and by AFI method it was 18.2 %. There was no statistical significant difference between the two groups in terms of rate of induction, mode of delivery, meconium staining of liquor, fetal heart rate tracings, APGAR score at 5 mins and admission to special care baby unit.Conclusion: In non-high risk pregnancy AFI technique detects slightly more number of oligohydramnios as compared to SDVP technique without apparently any difference in perinatal outcome.


Author(s):  
Dr. Girdhar Gopal Nagar ◽  
Dr. Sanjana Jourwal ◽  
Dr. Nishu Goyal

Polyhydramnios is defined as excessive accumulation of amniotic fluid in relation to gestational age usually more than 2000 ml. More recently when Amniotic Fluid Index is more than 95th and 97th percentile for the gestational age condition is called as polyhydramnios. It is frequently associated with congenital anomalies of the fetus. The aim of our study was to observe prevalence of congenital anomalies in polyhydramnios. The present study was carried out in the department of Obstetrics and Gynaecology Umaid Hospital attached to Dr. S. N. Medical College, Jodhpur. In this study patients of polyhydramnios with gestational age between 20 to 42 weeks with amniotic fluid index more than 24 were enrolled after taking informed written consent. Degree of polyhydramnios was graded as mild, moderate and severe. Detail study of fetus was done for possible congenital anomalies. Congenital anomalies were confirmed with post-natal findings. There were 196 pregnant women with amniotic fluid index (AFI) > 24 cm. Prevalence of polyhydramnios was 1.66%. Congenital anomalies were present in 16.84% out of total 196 cases of polyhydroamnios. In pregnant women with severe polyhydramnios 51.51 % and in moderate 45.45% had congenital anomalies. Most common congenital anomaly was anencephaly (3.57%) followed by Hydrops (3.57%), Central nervous system, gastrointestinal and skeletal anomalies. Polyhydramnios is associated with increased risk of congenital anomalies hence Intrauterine condition of fetus should be monitored by using various diagnostic facilities like USG, Doppler, Echo-cardiography, amniocentesis and cordocentesis for possible congenital anomalies.


2018 ◽  
Vol 8 (1) ◽  
pp. 25-29
Author(s):  
Subita Lalchan ◽  
Prakash Sharma ◽  
Sangeeta Devi Gurung

Introduction: Polyhydramnios is excessive amount of amniotic fluid in relation to gestational age. It is frequently associated with congenital anomalies of the fetus. The aim of this study was to see the prevalence of congenital anomalies in polyhydramnios.Methods: Singleton pregnant irrespective of gestational age with amniotic fluid index more than 25 were included in the study. Degree of polyhydramnios was graded as mild, moderate and severe. Detail study of fetus was done for possible congenital anomalies. Congenital anomalies were confirmed with post-natal findings.Results: There were 39 pregnant women with amniotic fluid index (AFI) > 25 cm. Prevalence of polyhydramnios was 0.3%. Congenital anomalies were present in 31.6 % of pregnant women with polyhydramnios. In pregnant women with severe polyhydramnios; 66.6 % had congenital anomalies. Central nervous system, gastrointestinal and skeletal anomalies were the frequent anomalies associated with polyhydramnios.Conclusion: Polyhydramnios is associated with increased risk of congenital anomalies hence a detail survey of fetus should be done for possible congenital anomalies.


Author(s):  
Prashant Patil ◽  
Archana Kumari ◽  
H. P. Anand

Background: Preterm premature rupture of membrane (PPROM) is among the most important cause of the perinatal morbidity and mortality. We sought to determine whether cervical length and amniotic fluid index individually or in combination can predict the pregnancy outcome in cases of PPROM.Methods: The prospective observational study was done on 170 women complicated by PPROM with gestational age between 24-36+6 weeks. They were categorized into three groups Group I.24-28 weeks, Group II.28+1 to 32 weeks and Group III. 32+1 to 36+6 weeks. Cervical length and amniotic fluid index were measured using trans abdominal ultrasound within 24 hr of admission. Maternal outcomes were recorded in terms of latency period, chorioamnionitis, and abruption , and neonatal outcomes were recorded in terms of birth weight, first minute APGAR score <7, NICU admission and early neonatal death. Qualitative variables were correlated using Chi-Square test /Fisher’s exact test. Univariate logistic regression was used to assess cervical length and AFI as a predictor of complication. A p value of <0.05 was considered statistically significant.Results: Out of 170, majority (95) belonged to 28+1 to 32 weeks group. Latency was inversely related to period of gestation (p<0.0001). A long cervical length correlated with increased latency, increased risk of chorioamnionitis and increased neonatal complications in all three groups. Also, women with PPROM having AFI >5 cm had a greater mean latency period (8.32±1.25 days) which increased their risk of developing chorioamnionitis as compared to women with PPROM having AFI ≤5 cm, who had a shorter mean latency period (7.63±1.07 days) and a lower risk of developing chorioamnionitis (p value <0.0001).Conclusions: Latency is inversely related to period of gestation. A long cervical length and increased amount of AFI correlates with increased latency, increased risk of chorioamnionitis and increased neonatal complications.


2016 ◽  
Vol 62 (3) ◽  
pp. 269-275 ◽  
Author(s):  
Alex Sandro Rolland Souza ◽  
Adriane Farias Patriota ◽  
Gláucia Virgínia de Queiroz Lins Guerra ◽  
Brena Carvalho Pinto de Melo

SUMMARY Objective: To determine the association between amniotic fluid index (AFI) and perinatal outcomes in preterm premature rupture of membranes (PPROM). Method: A retrospective cohort study was conducted between 2008 and 2012. 86 pregnant women were included, with a diagnosis of PPROM and gestational age from 24 to 35 weeks. Women who presented hypertensive disorders, diabetes, fetuses with birth defects and infection at admission were excluded. To determine the association between AFI and perinatal outcomes, chi-square and Fisher’s exact test were used if necessary, as well as risk ratio (RR) and 95% confidence intervals (95CI). Correlation between AFI and perinatal outcomes was determined by using simple linear regression, and AFI progression during pregnancy was analyzed by Z-test. Results: When comparing newborns presenting ultrasound with AFI<5cm and AFI>5cm, there was a higher frequency of perinatal mortality when the AFI was lower than 5 cm. However, when the oligohydramnios was diagnosed as severe (AFI<3cm), there was a higher frequency of Apgar scores less than seven at 1 minute, neonatal sepsis and early neonatal mortality compared to those presenting AFI>3cm. There was a positive correlation between AFI and gestational age at delivery, birth weight and Apgar scores at minutes 1 and 5. There was also a decrease in amniotic fluid volume with increased gestational age. Conclusion: The presence of severe oligohydramnios after PPROM contributed to a higher frequency of perinatal complications and death.


2019 ◽  
Vol 2 (1) ◽  
pp. 1-18
Author(s):  
Chijioke Okeudo ◽  
B.U. Ezem

Background: The amniotic fluid is fundamental for proper fetal development and growth. Ultrasound visualization of the amniotic fluid permits both subjective and objective estimates of the amniotic fluid. Objective: The objective of this study was to determine the reference values of normal single deepest pocket (SDP) – upper and lower limits, mean SDP and variation of the SDP with gestational age among Igbo women of South-Eastern Nigeria extraction carrying uncomplicated singleton pregnancy. Methodology: This was a prospective cross sectional study involving 400 women carrying uncomplicated singleton pregnancies and who were sure of the date of the first day of their last menstrual period. The single deepest pocket / maximum vertical pool were determined once at presentation at the hospital.. The study was conducted from January 1st to December 31st 2015. The second author carried out all the scanning. The SDP was obtained. Results: The womens’ mean and median ages were the same at 28 years. The gestational age range of the pregnancies was 14-41 weeks. The mean SDP was 5.8cm, while the 5th and 95th percentiles were 3.3cm and 8.5cm respectively. There was no difference in the mean SDP in both term and preterm. There was irregular but continuous rise of mean SDP to a peak of 6.8cm at gestational age of 39 weeks. In conclusion, the participants had a mean SDP of 5.8cm. There was also a positive correlation between SDP and Gestational age. We therefore recommend a longitudinal study to assess perinatal outcome and abnormal amniotic fluid volume among Igbo women of South-Eastern Nigeria. Key words: Single Deepest Pocket, Uncomplicated Singleton Pregnancy, Igbo Women.


2011 ◽  
pp. 20-24
Author(s):  
Thi My Dung Ha ◽  
Ngoc Thanh Cao ◽  
Thi Song Huong Tran

Objective: To characterize ultrasound images of placenta and amniotic fluid in cases of singleton pregnancies beyond term predictions, and also explore the relationship between placenta, amniotic fluid and labor transfer status, postpartum child status. Image properties of prenatal placenta and amniotic fluid are immediately examined with ultrasound in 267 cases of postterm pregnancy beyond prediction at Obstetric Department, Hue Central Hospital. Results: In postterm pregnancy, placenta thickness decreases gradually according to gestational age. Oligohydramnios is 30.3%. There is a correlation between amniotic fluid index and birth method with r = 0.41. Sensitivity is 89.15%. Specificity is 48.55%. There is also a correlation between amniotic fluid echogenicity and method of birth: r = 0.478. Sensitivity is 97.67%. Specificity is 42.75%. Amniotic fluid index and baby Clifford's syndrome are also relevant, with r=0.466. Sensitivity is 83.78%. Specificity is 78.26%. Conclusions: Ultrasound scanning of amniotic fluid properties should be noted in the case of postterm pregnancy.


2021 ◽  
pp. 004947552199134
Author(s):  
Avinash Lomash ◽  
Abhinaya Venkatakrishnan ◽  
Meenakshi Bothra ◽  
Bhavna Dhingra ◽  
Praveen Kumar ◽  
...  

Atypical coeliac disease in young children is frequently missed when it presents atypically as non-gastrointestinal presentations to different specialties. There was a greater delay (54 months) in establishing the diagnosis in those with atypical coeliac disease (p < 0.001). No difference was observed in the mode of delivery or duration of breast feeding, but significant difference was observed between gestational age at birth (p < 0.001). Most cases showed stunted growth and underweight. Irritability, anaemia, rickets, dermatitis herpetiformis, alopecia and intussusception were other common predictors of atypical coeliac disease. Because of a myriad spectrum of non-gastrointestinal symptoms, at any age with diverse presentation, a high index of suspicion is therefore required.


2020 ◽  
Vol 47 (12) ◽  
pp. 865-872 ◽  
Author(s):  
Natalie E. Rintoul ◽  
Roberta L. Keller ◽  
William F. Walsh ◽  
Pamela K. Burrows ◽  
Elizabeth A. Thom ◽  
...  

<b><i>Introduction:</i></b> The Management of Myelomeningocele Study was a multicenter randomized trial to compare prenatal and standard postnatal repair of myelomeningocele (MMC). Neonatal outcome data for 158 of the 183 randomized women were published in <i>The New England Journal of Medicine</i> in 2011. <b><i>Objective:</i></b> Neonatal outcomes for the complete trial cohort (<i>N</i> = 183) are presented outlining the similarities with the original report and describing the impact of gestational age as a mediator. <b><i>Methods:</i></b> Gestational age, neonatal characteristics at delivery, and outcomes including common complications of prematurity were assessed. <b><i>Results:</i></b> Analysis of the complete cohort confirmed the initial findings that prenatal surgery was associated with an increased risk for earlier gestational age at birth. Delivery occurred before 30 weeks of gestation in 11% of neonates that had fetal MMC repair. Adverse pulmonary sequelae were rare in the prenatal surgery group despite an increased rate of oligohydramnios. There was no significant difference in other complications of prematurity including patent ductus arteriosus, sepsis, necrotizing enterocolitis, periventricular leukomalacia, and intraventricular hemorrhage. <b><i>Conclusion:</i></b> The benefits of prenatal surgery outweigh the complications of prematurity.


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