scholarly journals Rare case reports of ruptured ectopic pregnancy

2018 ◽  
Vol 7 (12) ◽  
pp. 5201
Author(s):  
Dhrubal Prasad Paul ◽  
Dibakar Debbarma ◽  
Ashis Kumar Rakshit
Keyword(s):  
Ectopic Pregnancy ◽  
Histopathological Examination ◽  
Case Reports ◽  
Emergency Laparotomy ◽  
Blood Products ◽  
Unstable Condition ◽  
Medical College ◽  
Base Level ◽  
Partial Mole

Two patients of 30-35 years of age presented in Gynecological emergency of Agartala Government Medical College at unstable condition with the diagnosis of ruptured ectopic pregnancy. Both the cases were taken for emergency laparotomy after initial resuscitation, investigations & arrangement of blood products. In both the cases rupture were found in right side and hence right sided salpingectomy done in both the cases. Both the tubes (affected) after laparotomy were sent for histopathological examination where both the reports came to be partial mole. Ectopic hydatiform mole (either complete or partial) are rare events, among these Ectopic partial moles are rarer. Both the cases were in regular follow up & ß-HCG levels came to the base level within 6-7 wks. The 1st case became pregnant after 9 months of laparotomy.

scholarly journals Histopathological Analysis of Endometrial Biopsy in Gandaki Medical College Teaching Hospital, Pokhara, Nepal

2019 ◽  
Vol 12 (1) ◽  
pp. 25-30
Author(s):  
B Parajuli ◽  
G Pun ◽  
S Ranabhat ◽  
S Poudel
Keyword(s):  
Histopathological Examination ◽  
Hydatidiform Mole ◽  
College Teaching ◽  
Histopathological Diagnosis ◽  
Age Group ◽  
Medical College ◽  
Dilatation And Curettage ◽  
Partial Mole ◽  
Proliferative Endometrium ◽  
The Common

Objective: To study the spectrum of histopathological diagnosis of endometrial lesions and their distribution according to age. Methods: All the endometrium samples obtained by the procedure of dilatation and curettage and hysterectomy sent for histopathological examination at Pathology Department of Gandaki Medical College Teaching Hospital, Pokhara, Nepal. The study duration was total 12 months ranging from July 2016 to June 2017. All the endometrial samples were processed, sectioned at 4 - 6 μm and stained with routine H & E stain. Patient’s data including age, sex, procedure of the biopsy taken and histopathological diagnosis were noted. A pathologist, using Olympus microscope, reported the slides. Cases were reviewed by a second pathologist whenever necessary. Results: A total of 128 cases were studied. The most common histopathological diagnosis was proliferative endometrium (28.9%) followed by disorder proliferative endometrium (15.65%). Most of the patients were in age group 36 - 45 years comprising 32.03%. Hydatidiform mole comprised of 7.03% and among Hydatidiform mole, partial mole was more common. Dilatation and curettage (82.8%) was the common procedure in compare to hysterectomy for the evaluation of endometrial lesions. Conclusions: In this study, we observed a variety of endometrial lesions. Most of them are benign; among benign, proliferative endometrium was the common histopathological diagnosis followed by disorder proliferative endometrium. Most common presenting age group was found to be at 36 - 45 years. In evaluation of hydatidiform mole, partial mole was more frequent in compare to complete mole. Conventional dilatation and curettage is the preferred method in developing countries with limited resource to screen endometrial lesion and therefore biopsy should be sent for histopathological examination. Thus histopathological examination of routinely stained hematoxylin and eosin is readily available and widely accepted standard technique for evaluation of the endometrial lesions.

scholarly journals SCROTAL CALCINOSIS - RARE CASE REPORTS OF TWO CASES

2012 ◽  
Vol 02 (02) ◽  
pp. 57-59
Author(s):  
Harish S. Permi ◽  
Rohan Shetty ◽  
Shalmali Alva ◽  
Balakrishna Shetty ◽  
Rajesh Ballal ◽  
...  
Keyword(s):  
Giant Cell ◽  
Rare Case ◽  
Histopathological Examination ◽  
Case Reports ◽  
Amorphous Material ◽  
Benign Disease ◽  
Cell Reaction ◽  
Granulomatous Reaction ◽  
Large Size

AbstractScrotal calcinosis is a benign disease characterized by multiple calcified scrotal nodules. The nodules develop slowly over many years and patients usually do not seek for treatment, until they grow to large size. Histopathological examination shows deposition of basophilic amorphous material surrounded by giant cell granulomatous reaction. We report two cases of scrotal calcinosis occurring in 27 year and 45 year old males who presented with multiple scrotal swellings. Clinical diagnosis was multiple sebaceous cysts. On histopathology, excised swellings showed deposition of calcium with giant cell reaction. On regular follow up both are doing fine without any recurrence.

scholarly journals The Challenge of the Non-Compliant Patient: A Case of Caesarean Section Scar Ectopic Pregnancy

2021 ◽  
pp. 1-3
Author(s):  
Jessica Audet ◽  
Brittany Noel Robles ◽  
Nicolle M Arroyo Lluberas ◽  
Jessica Audet ◽  
Daniel Faustin ◽  
...  
Keyword(s):  
Ectopic Pregnancy ◽  
Emergency Laparotomy ◽  
Pharmacological Management ◽  
Compliant Patient ◽  
Life Saving ◽  
Close Observation ◽  
Life Threatening ◽  
History Of ◽  
Ruptured Uterus

Ectopic pregnancy is a quite common and life-threatening pregnancy. The most common site of ectopic implantation of a fertilized embryo is the fallopian tube. In extremely rare situations, the embryo can implant in other locations, which makes the diagnosis and management even more complex. Although close observation of a new pregnancy is key in the diagnosis and treatment of an ectopic pregnancy, there is still a major risk of life-threatening outcomes. This is a case report of a 31-year-old patient with a history of multiple pregnancies who presented to a community hospital in the spring of 2021 with an ectopic caesarean scar pregnancy. A diagnosis of ectopic pregnancy was on a timely basis, and surgical management was advised. Upon refusal of treatment and admission, pharmacological management was initiated, but patient compliance challenged the success of the therapy. Patient non-compliance to close follow-up resulted in a ruptured uterus. Emergency laparotomy with supracervical hysterectomy was performed as a life-saving procedure.

scholarly journals Histopathological examination of tissues following a surgical uterine evacuation in the first trimester bleeding: clinical relevance

2020 ◽  
Vol 10 (3) ◽  
pp. 91-94
Author(s):  
Bandana Khanal ◽  
Basant Sharma ◽  
Renuka Tamrakar ◽  
Prekshya Singh
Keyword(s):  
Clinical Relevance ◽  
Histopathological Examination ◽  
First Trimester ◽  
Gestational Trophoblastic Disease ◽  
Complete Mole ◽  
Products Of Conception ◽  
Partial Mole ◽  
History Of

Background: There is no general consensus about the role of routine HPE of the obtained tissue at the time of uterine evacuation. However, it is understood clinically that it is of utmost importance to prove the presence of intrauterine gestation and to exclude gestational trophoblastic disease in the form of partial or complete mole. This study aimed to assess the role of histopathology in cases of first trimester miscarriages and to determine clinical relevance of histopathological examination following surgical evacuation. Methods: This was a retrospective study of collected data over 12 months (January 2018- De­cember 2018) in an agency for reproductive health setup with predefined inclusion criteria. We included 60 consecutive patients attended with history of first trimester bleeding. Patient’s record and the histopathological examination report of products of conception following uterine evacu­ation were observed. The data was analyzed descriptive statistics including percentage, stander deviation, mean, and range in Microsoft Excel software. Results: Missed abortion was the most common type and constituted 55% of the studied group. The histopathological reports confirmed the pregnancy in all patients and revealed partial mole in 6(10%) patients and complete mole in 2(3.33%) patients. Conclusions: Histopathological examination of products of conception detects under diagnosed molar pregnancies that necessitates special follow up and is a key step to do further management.

A positive urine pregnancy test (UPT) with adnexal mass; ectopic pregnancy is not the ultimate diagnosis

2018 ◽  
Vol 0 (0) ◽  
Author(s):  
Mohd Faizal Ahmad ◽  
Muhammad Azrai Abu ◽  
Kah Teik Chew ◽  
Kun Leng Sheng ◽  
Mohd Asyraf Zakaria
Keyword(s):  
Ectopic Pregnancy ◽  
Adnexal Mass ◽  
Case Reports ◽  
First Trimester ◽  
Pregnancy Test ◽  
First Case ◽  
Positive Urine ◽  
Disease Free ◽  
Urine Pregnancy Test

Abstract A positive urine pregnancy test (UPT) with adnexal mass in ectopic pregnancy is not the ultimate diagnosis. The incidence of ectopic pregnancy is about 27 per 1000 pregnancies [1]. On average, about 6–16% will present to an emergency department with first-trimester bleeding and abdominal pain [2]. On presenting with these symptoms with the simultaneous presence of an adnexal mass and an empty uterus, a UPT is of paramount importance to determine whether the symptoms are pregnancy related or not. When the UPT is positive, an ectopic pregnancy is not the only diagnosis as the rare entity of non-gestational ovarian choriocarcinoma (NGOC) should be considered. Here we present two case reports of NGOC, which were initially diagnosed as ectopic pregnancy. The first case is a 16-year-old girl, with vaginal bleeding and an adnexal mass due to an ovarian choriocarcinoma, She underwent unilateral oophorectomy and received multiple courses of chemotherapy. She is disease free without evidence of recurrence or metastasis after 12 months of follow-up. The second patient is also 16 years old and presented with an acute abdomen. She was diagnosed as a ruptured luteal cyst and underwent partial oophorectomy. When the pathologist diagnosed a choriocarcinoma she received multiple courses of chemotherapy, but thereafter an advanced disease was diagnosed with evidence of distant metastasis.

scholarly journals Tubal Ectopic Pregnancy after 11 Years of Bilateral Tubal Ligation

2015 ◽  
Vol 7 (1) ◽  
pp. 119-120
Author(s):  
Mosammat Bilkis Parvin ◽  
Kazi Sahnaz Begum ◽  
Naseem Jahan ◽  
Hasina Sultana
Keyword(s):  
United States ◽  
Ectopic Pregnancy ◽  
Caesarean Delivery ◽  
Tubal Ligation ◽  
First Year ◽  
Contraceptive Methods ◽  
Tubal Ectopic Pregnancy ◽  
Medical College ◽  
Permanent Contraception

Tubal ligation is a well excepted method of contraception. Permanent contraception by tubal ligation is one of the most commonly used contraceptive methods in United States, also most popular form of contraception worldwide. Although pregnancy after ligation is uncommon, it can occur and may be ectopic. Surprisingly, failures are not limited to the first year or two but continued to appear even after many years during follow up. In this paper we report a case of ectopic pregnancy in a patient who underwent bilateral tubal ligation11years ago during caesarean delivery for contraception.Northern International Medical College Journal Vol.7(1) Jul 2015: 119-120

scholarly journals Ovarian Pregnancy- A Rare Case Report

2019 ◽  
Vol 10 (2) ◽  
pp. 183-185
Author(s):  
Sehereen Farhad Siddiqua ◽  
Sharmin Abbasi ◽  
Shifin Rijvi ◽  
Abrar Saqif Hasan
Keyword(s):  
Ectopic Pregnancy ◽  
Histopathological Examination ◽  
Wedge Resection ◽  
First Trimester ◽  
Medical College ◽  
Ovarian Pregnancy ◽  
Rare Case Report ◽  
Intraperitoneal Bleeding ◽  
Uncommon Case ◽  
Ectopic Pregnancies

Ovarian pregnancy is a rare form of the non-tubal ectopic pregnancy. Primary ovarian ectopic pregnancy means  implantation of the gestational sac in the ovary. Its incidence after natural conception ranges from 1 in 2000 to 1  in 60 000 deliveries and accounts for 3% of all ectopic pregnancies. It ends with rupture before the end of the  first trimester. The preoperative diagnosis of this type of pregnancy is not easy. It is characterized by a poor  clinical symptomatology and a difficult ultrasound diagnosis but confirmed by histological findings. For the  management, Conservative laparoscopic surgery involves ovarian resection or aspiration of the pregnancy with  coagulation of the implantation site. However, in case with profuse intraperitoneal bleeding an oophorectomy or  salpingo-oophorectomy may be necessary to achieve hemostasis. We report here one such uncommon case of  ovarian ectopic pregnancy. Our patient is a 27 years old nulliparous woman came with severe hypogastric pain.  During laparoscopy, ruptured ovarian ectopic pregnancy was diagnosed, and wedge resection of the ovary was only done. Histopathological examination confirmed it to be an ovarian ectopic pregnancy. Anwer Khan Modern Medical College Journal Vol. 10, No. 2: July 2019, P 183-185

scholarly journals Comparative study of rapid urease test and histopathological examination for detection of H. pylori infection

2017 ◽  
Vol 4 (12) ◽  
pp. 4071
Author(s):  
Virendra S. Athavale ◽  
Vinit Singh ◽  
Shivmurti N. Khandalkar ◽  
Dakshayani S. Nirhale ◽  
Aditya Lad ◽  
...  
Keyword(s):  
Histopathological Examination ◽  
Good Alternative ◽  
Gastric Biopsy ◽  
Rapid Urease Test ◽  
Study Group ◽  
Medical College ◽  
Urease Test ◽  
Resource Poor ◽  
H Pylori

Background: Aims and objectives of the study was to study the incidence of H. pylori infection in our Hospital. To find out the sensitivity and specificity of rapid urease test (RUT) and histopathological examination for the detection of H. pylori on gastric biopsy. To study the effect of anti H. pylori drugs by performing follow-up endoscopy in terms of positive or negative Rapid Urease Test and Histopathological Examination report.Methods: The study was conducted at Dr. D. Y. Patil Medical College and Hospital, DPU University, for a period of 2 years (from July 2012-September 2014) and is a prospective and comparative randomized type of study using 100 patients. The study was approved by the Institute’s Ethics Committee.Results: Data analysis showed that: In our study 84 patients (84%) were detected positive by RUT method. In our study 83 patients (83 %) were detected positive by HPE method. There was an association between RUT and HPE finding in study group with the sensitivity being 96.38 % and specificity being 74.47 %, PPV was 95.24% and NPV was 81.25%. At the time of follow up after taking anti H pylori treatment, 79 patients were RUT negative and 8 were RUT positive who were defaulters (not taken complete dose) and again started on treatment with the accuracy of the drug being 98.85 %. At the time of follow up after taking anti H pylori treatment 78 patients were HPE negative and 9 were HPE positive who were defaulters (not taken complete dose) and again started on treatment. There was an association between RUT and HPE finding at follow up with the sensitivity being 88.89 % and specificity being 100%, PPV was 100% and NPV was 98.73%.Conclusions: Our study reveals that RUT is accurate for the diagnosis of H. pylori infection and its use will serve as a good alternative to histology in management of patients with dyspepsia in resource poor environments, except in patients who need histology for reasons other than H. pylori diagnosis.

A positive urine pregnancy test with haemoperitoneum: misdiagnosed postpartum choriocarcinoma with uterine rupture mimicking ruptured ectopic pregnancy

2021 ◽  
Vol 0 (0) ◽  
Author(s):  
Shakti Yeoh ◽  
Soon-Leong Yong ◽  
Pak-Inn Teoh ◽  
Marcus Kang
Keyword(s):  
Ectopic Pregnancy ◽  
Uterine Rupture ◽  
Histopathological Examination ◽  
Wedge Resection ◽  
Total Abdominal Hysterectomy ◽  
Abdominal Hysterectomy ◽  
Emergency Laparotomy ◽  
Blood Product Transfusion ◽  
Pregnancy Test ◽  
Urine Pregnancy Test

Abstract Objectives Choriocarcinoma after a term pregnancy is rare and can be life-threatening, especially when it perforates the uterus, resulting in massive haemoperitoneum. As uterine rupture due to choriocarcinoma is uncommonly encountered in the clinical practice, its diagnosis is often missed or delayed. Case presentation We present a case of a 41-year-old para 4 + 1 who had acute abdomen and hypovolaemic shock secondary to haemoperitoneum at three months postpartum period. The urine pregnancy test was positive, and, therefore, a provisional diagnosis of a ruptured ectopic pregnancy was made. She was managed aggressively with fluids and blood product transfusion at the emergency department to achieve haemodynamic stability. Subsequently, she underwent an emergency laparotomy where intraoperatively noted a perforation at the left posterior uterine cornu with purplish tissue spillage. A wedge resection was performed, and the histopathological examination (HPE) was reported as atypical trophoblastic cells, in which choriocarcinoma could not be ruled out. The patient then underwent a total abdominal hysterectomy three weeks later. The final HPE confirmed the diagnosis of choriocarcinoma. Conclusions The clinical presentation of postpartum choriocarcinoma can be indistinguishable from a ruptured ectopic pregnancy. A high index of suspicion is crucial to allow early diagnosis.

Aggressive Cushing disease five years after the treatment of a nonfunctional pituitary adenoma

2016 ◽  
Vol 62 (5) ◽  
pp. 77-78
Author(s):  
Minodora Betivoiu ◽  
Sorina Martin ◽  
Iulia Soare ◽  
Alexandra Nila ◽  
Simona Fica
Keyword(s):  
Pituitary Adenoma ◽  
Gamma Knife ◽  
Pituitary Adenomas ◽  
Histopathological Examination ◽  
Case Reports ◽  
Dependent Diabetes Mellitus ◽  
Ki 67 ◽  
The Right ◽  
Gamma Knife Therapy

Introduction. Cushing's disease (CD) represents 10%–12% of all pituitary adenomas and is seen predominantly in women, with a female-to-male ratio of 8:1. Although most patients with ACTH-secreting adenomas present with benign, small tumors, some have invasive macroadenomas. Rarely, nonfunctional pituitary adenomas (NFPAs) may gain secretory function, but there have been a few case reports of metamorphosis to CD.Case report. We report the case of a 59-year-old female diagnosed in 2007 with a NFPA and panhypopituitarism. She had two transsphenoidal surgeries and Gamma Knife therapy and started replacement treatment with levothyroxine 75mcg/day and prednisone 5mg/day. The postoperative course was favorable and imagistic follow-up between 2007-2014 showed progressive reduction of the residual tumor and empty sella. From personal history we note noninsulin-dependent diabetes mellitus, postmenopausal osteoporosis treated with bisphosphonates. In January 2015 she suffered visual loss on the right eye. Pituitary MRI showed supra and parasellar tumor recurrence of 27/24/17mm, infiltrating the right side of the cavernous sinus, extending around the right internal carotid artery and optic nerve, compressing the optic chiasm. In March 2015 a third transsphenoidal partial excision of the tumor was performed and in August Gamma Knife therapy was repeated. The histopathological examination was consistent with a pituitary adenoma but immunohistochemical staining for ACTH was positive, with Ki-67=25%. She had no non-specific cushingoid features. Laboratory test: glucose=116mg/dl, HbA1c=7.5%, FSH=3.34mIU/ml, LH=0.585mIU/ml TSH=0.044mcIU/ml, FT4=1.13ng/dl. Prednisone replacement therapy was stopped and CD was confirmed: 8AMcortisol=13.3mcg/dl, 23PMcortisol=11.3mcg/dl, ACTH=70.2pg/ml, 8AMcortisol after 1mg dexamethasone overnight=13.8mcg/dl. Ophthalmic exam: blindness in the right eye, slightly decreased visual field in the left eye. Pituitary MRI 8-month postsurgery revealed a 28/31/28mm invasive tumor. We started treatment with Cabergoline 3mg/week and recommended closely biological and imagistic follow-up, hoping for a good response to radiotherapy.Conclusions: Our case stresses the importance of regular, lifelong follow-up of patients with NFPAs. Chiloiro et al have reported that pituitary adenomas with Ki-67≥1.5% have a higher risk of recurrence. Although the characteristics of patients with CD have been well known for decades, the diagnosis and management of this disease are often challenging.

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