scholarly journals Evaluation of perinatal outcome in high-risk pregnancy at tertiary care centre

Author(s):  
Anupam Rani ◽  
Urmila Karya ◽  
Sweta Kumari

Background: A high risk pregnancy is one in which mother, fetus or neonate is at increased risk of morbidity or mortality before or after delivery. Hence a relatively small percentage of high risk obstetric population gives rise to a disproportionately high percentage of perinatal and maternal morbidity and mortality. The perinatal outcome can be changed significantly by early detection and special intensive care to high risk pregnancies. Hence Identification of women at risk for these complicated pregnancies with poor outcome is fundamental to antenatal check-up.Methods: 86 high risk antenatal patients attending the outpatient department and labour room were recruited after informed consent.70 normal pregnancy was taken as control group. Perinatal outcomes were compared between high risk and normal pregnancies.Results: Adverse perinatal outcomes were more in high risk pregnancies as compared to normal pregnancies.Conclusions: This study emphasizes on pregnancy related complication leading to adverse perinatal outcome so evaluating patients for high risk factors, early diagnosis, proper antenatal care, prompt treatment, regular follow up, and timely management thus can improve maternal and perinatal outcome.

Author(s):  
Narendra Vaghela

Introduction: In normal married couple or married women pregnancy is normal physiological condition and not a high-risk condition. Most of the pregnancies have happy outcome with good health of both foetus and mother whereas some pregnancies are complicated by problems with mother’s health, the health of the foetus or complications unique to pregnancy. Like these kinds of complicated pregnancies are group as “high risk” for developing problems and having a poor outcome. In comparing to the normal pregnancy High-risk pregnancy is one of greater risk to the mother or her fetus. A High risk (at risk) pregnancy cases there is increased in risk of morbidity or mortality before or after delivery where the mother, fetus, or neonate. At the time of pregnancy, a high-risk pregnancy is grouped in which past reproductive performance or maternal environment presents a significant risk to foetus such as premature birth, small for date infant, full term with low reservoir or still births and early neonatal death. For pregnant women identification of at high risk for these complicated pregnancies with poor outcome is fundamental to antenatal care. The risk factors which include high risk pregnancy are existing medical conditions such as HIV positive, Diabetes mellitus and BP as well as maternal obesity, multiple births and young or old age. A number of biological and social factors such as age, social class, parity and past obstetric history, occupation and psycho social factors and nutritional status that influence the perinatal outcome during pregnancy. Aim: The main aim of this study is to pregnancy outcome in various high-risk pregnancies. Material and Methods: This study was prospective study in which total 100 high risk and 100 low risk caesarean cases were done.  In all the cases married women were included with the age from 20 to 40 years old having gestational age of more than 28 wks and underwent Caeserian section (Emergency/elective). In this study both IPD and OPD patients were included.  In IPD cases in general had minimum of two antenatal check-ups. At the time of admission detail history of patients was taken including age, address and occupation, menstrual history, obstetrical history regarding gravity, parity abortion, number of term & preterm labours, any history of previous CS, indication for CS and intra-operative complication. For all the patients scoring was done as low risk and high risk cases by modified Coopland’s Scoring System.  In the case of cesarean section Breast feeding was stated after 4 hours. Detailed information and history of neonatal complication and perinatal outcome was also recorded using predesigned and pretested proforma. Result: In this study to total 100 high risks as a study group and 100 low risks as a control group caesarean case with perinatal outcome was recorded. 42% and 30% of the study and control group respectively had low birth weight baby. In the high risk group, 3% had neonatal death while in control group there was 0% respectively. 38% babies in this study group and 17% babies in the control group had mild to severe depression and Apgar score below 6-4. Conclusion:  This study showed pregnancy complications and related perinatal morbidity as risk factors impacting on neonatal outcome. If mother had access to appropriate and timely healthcare during pregnancy majority of maternal morbidities could be prevented.  Hence proper care and timely referral can have a positive impact in lowering the perinatal mortality and morbidity and possibly better maternal outcome. Keywords: Pregnancy outcome, High risk pregnancy, Perinatal outcome, Coopland scoring, Caesarian section


2021 ◽  
Vol 6 (2) ◽  
pp. 185-191
Author(s):  
Hiral Parekh ◽  
Sneha Chaudhari

This was a prospective study conducted in pregnant patients with high risk factors who got admitted in the Department of Obstetrics and Gynaecology at Care Hospital, Jamnagar during the period from May 2018 to September 2020. Background: High-risk pregnancies causes many adverse perinatal outcomes. Doppler ultrasound is a non-invasive technique to study the feto-maternal circulation to guide the clinical management. Objective: This study aims at evaluating the role of colour Doppler in high-risk pregnancies and their perinatal outcome. Materials and Methods: This was a prospective study carried out for 29 months in the Department of Radiology with antenatal women in the age group of 18-35 years with singleton pregnancy of gestational age of <28 weeks to >35 weeks having high-risk factors considered in study. The risk factors considered were pregnancy induced hypertension (PIH), gestational diabetes, anemia, oligohydramnios, polyhydramnios and IUGR. Doppler study of umbilical artery and fetal middle cerebral artery (MCA) arteries was done and amniotic fluid index (AFI) was measured. Parameters in the form of resistive index, pulsatility index, and systolic/diastolic ratio were taken. obstetric history was taken with regular interval follow up. Results: The study was carried out with 50 patients. High-risk pregnancy was more common in the age group of 21-25 years. The most common high-risk factor in pregnancy was oligohydramnios which accounted for 30% of cases. Out of 50 high-risk pregnancies, 5 (10 %) of cases resulted in intrauterine growth restriction (IUGR). Out of 50 high-risk cases, in 36 cases, umbilical artery findings were abnormal. 3 patients had intrauterine death (IUD) and 27 patients had poor perinatal outcome. Umbilical artery abnormality showed significant sensitivity and negative predictive value for adverse (poor + IUD) perinatal. Correlation was seen between high risk pregnancy and need of emergency caesarean section and induction and associated adverse perinatal outcome. Conclusion: Combination of different arterial waveform study enhance the diagnostic accuracy in identifying those intrauterine growth restricted foetuses that were at risk. Keywords: Colour Doppler, high risk pregnancy, perinatal outcome.


2021 ◽  
pp. 1-9
Author(s):  
Nazlı Baltacı ◽  
Mürüvvet Başer

<b><i>Background:</i></b> Women with high-risk pregnancy experience anxiety and low mother-fetal attachment when faced with signs of danger and health problems. This study aimed to investigate the effects of lullaby intervention on anxiety and prenatal attachment in women with high-risk pregnancy. <b><i>Materials and Methods:</i></b> This randomized controlled trial was conducted in the perinatology clinic of a state maternity hospital in Turkey. Seventy-six women with high-risk pregnancy were included. The intervention group listened to lullabies for 20 min once a day, and accompanied by lullabies touched their abdomen and thought about their babies, but the control group did not. Data were collected using the Pregnant Information Form, the State Anxiety Inventory, and the Prenatal Attachment Inventory. <b><i>Results:</i></b> Baseline anxiety did not differ in the intervention versus control group (47.83 ± 10.74 vs. 44.10 ± 8.08, mean difference 3.73 [95% Cl –1.18 to 8.64], <i>p</i> = 0.13), but after the 2nd day lullaby intervention anxiety was lower in the intervention group versus control group (33.66 ± 9.32 vs. 43.06 ± 8.10, mean difference –9.40 [95% Cl –13.91 to –4.88], <i>p</i> &#x3c; 0.01). Baseline prenatal attachment did not differ in the intervention versus control group (56.03 ± 10.71 vs. 53.86 ± 9.98, mean difference 2.16 [95% Cl –3.18 to 7.51], <i>p</i> = 0.42), but after the 2nd day lullaby intervention prenatal attachment was higher in the intervention group versus control group (66.70 ± 7.60 vs. 54.36 ± 9.52, mean difference 12.33 [95% Cl 7.87 to 16.78], <i>p</i> &#x3c; 0.01). In the within-group analysis the intervention group had lower anxiety and better prenatal attachment (<i>p</i> &#x3c; 0.01), but not in the control group (<i>p</i> &#x3e; 0.05). <b><i>Conclusion:</i></b> Lullaby intervention can play an effective role in reducing anxiety and improving prenatal attachment. The use of this integrative, noninvasive, non-pharmacologic, time-efficient, and natural intervention is suggested in the care of pregnant women.


Author(s):  
María Florencia Angueyra ◽  
Débora Natalia Marcone ◽  
Florencia Escarrá ◽  
Noelia Soledad Reyes ◽  
Yamile Rubies ◽  
...  

Abstract Objective: To report a conjunctivitis outbreak in a neonatology intensive care unit (NICU) and determine the associated economic impact. Design: Prospective observational study. Setting: Centro de Educación Médica e Investigaciones Clínicas (CEMIC) University Hospital, a private, tertiary-care healthcare institution in Buenos Aires, Argentina. Participants: The study included 52 NICU neonates and 59 NICU-related healthcare workers (HCWs) from CEMIC hospital. Methods: Neonates and HCWs were swabbed for real-time polymerase chain reaction (PCR) testing, viral culture, and typing by sequencing. Infection control measures, structural and logistic changes were implemented. Billing records were analyzed to determine costs. Results: From January 30 to April 28, 2018, 52 neonates were hospitalized in the NICU. Among them, 14 of 52 (21%) had bilateral conjunctivitis with pseudomembranes. Symptomatic neonates and HCWs were HAdV-D8 positive. Ophthalmological symptoms had a median duration of 18 days (IQR, 13–24.5). PCR positivity and infectious range had a median duration of 18.5 days. As part of containment measures, the NICU and the high-risk pregnancy unit were closed to new patients. The NICU was divided into 2 areas for symptomatic and asymptomatic patients; a new room was assigned for the general nursery, and all deliveries from the high-risk pregnancy unit were redirected to other hospitals. The outbreak cost the hospital US$205,000: implementation of a new nursery room and extra salaries cost US$30,350 and estimated productivity loss during 1 month cost US$175,000. Conclusions: Laboratory diagnosis confirmed the cause of this outbreak as HAdV-D8. The immediate adoption and reinforcement of rigorous infection control measures limited the nosocomial viral spread. This outbreak represented a serious institutional problem, causing morbidity, significant economic loss, and absenteeism.


2018 ◽  
Vol 7 (43) ◽  
pp. 4603-4608
Author(s):  
Harshika Singh ◽  
Manjusha Agrawal ◽  
Arvind Bhake ◽  
Nihar Gupta

2020 ◽  
pp. 1-3
Author(s):  
Karishma Gandhi ◽  
Ishit Shah ◽  
Ram Kumar Patidar

Background: High risk pregnancy needs special antepartum as well as intrapartum care and investigations. CTG is aadmissionscreening test to monitor fetal wellbeing by use of cardiotocograph. It monitors fetal heart rate and uterine contractions. Color Doppler is ultrasound dependent test which uses vascular flow velocities and Doppler waveform to predict fetal outcome. Objective: Comparison of efficiency of CTG & Color Doppler ultrasound for intrapartum fetal surveillance in high risk pregnancy. Methods: Retrospective study of 100 high risk pregnancies of ≥ 34 weeks POG in labor with CTG and color Doppler findings were done on admission at Gujarat Adani Institute of Medical Sciences, Bhuj. Subjects were classified into 4 groups based on CTG and color Doppler findings. Maternal and fetal outcome were recorded and correlated with CTGand color Dopplerfindings. Results: Most common cause of high-risk pregnancy was preeclampsia(n=60/100,60%).In our study, rate of normal delivery was 40% and c-section was 60% (31% elective & 29% emergency). Out of 100 fetuses, 76 were healthy, 22 were admitted in NICU (6 NICU deaths) and 2 were still birth. Perinatal outcome was most favorable with normal CTG and Color doppler and was least favorable with both of them abnormal. Outcome was intermittent in other two groups. CTG found to have sensitivity 62.5% and specificity 82.5% in detection of adverse fetal outcome. Similarly,sensitivity and specificity of color doppler was 48.8% and 98.6% respectively. Conclusions: In our study it was found that CTG is more sensitive and color Doppler is more specific in detection of adverse fetal outcome.


2020 ◽  
Vol 9 (8) ◽  
pp. 2449 ◽  
Author(s):  
Shanny Sade ◽  
Eyal Sheiner ◽  
Tamar Wainstock ◽  
Narkis Hermon ◽  
Shimrit Yaniv Salem ◽  
...  

Objective: Higher rates of mental disorders, specifically depression, were found among affected people in previous epidemiological studies taken after disasters. The aim of the current study was to assess risk for depression among pregnant women hospitalized during the “coronavirus disease 2019” (COVID-19) pandemic, as compared to women hospitalized before the COVID-19 pandemic. Study design: A cross-sectional study was performed among women hospitalized in the high-risk pregnancy units of the Soroka University Medical Center (SUMC). All participating women completed the Edinburgh Postnatal Depression Scale (EPDS), and the results were compared between women hospitalized during the COVID-19 strict isolation period (19 March 2020 and 26 May 2020) and women hospitalized before the COVID-19 pandemic. Multivariable logistic regression models were constructed to control for potential confounders. Results: Women hospitalized during the COVID-19 strict isolation period (n = 84) had a comparable risk of having a high (>10) EPDS score as compared to women hospitalized before the COVID-19 pandemic (n = 279; 25.0% vs. 29.0%, p = 0.498). These results remained similar in the multivariable logistic regression model, while controlling for maternal age, ethnicity and known mood disorder (adjusted odds ratio (OR) 1.0, 95% CI 0.52–1.93, p = 0.985). Conclusion: Women hospitalized at the high-risk pregnancy unit during the COVID-19 strict isolation period were not at increased risk for depression, as compared to women hospitalized before the COVID-19 pandemic.


2020 ◽  
pp. 19-27
Author(s):  
L. V. Tsallagova ◽  
L. V. Maisuradze ◽  
S. V. Sagkaeva ◽  
T. I. Tsidaeva

Summary. Purpose of research. Development of a method for prevention of placental insuffi ciency (PN) in high-risk pregnancy in women of the Republic of North Ossetia-Alania (RSO-A) with the complex use of antihypoxant limontar and ozone therapy (OT). Material and methods. Observations were made of 75 pregnant residents of RSO-A with diagnosed PN, whose average age was 32,6 ± 8,14 years. Using a simple randomization method, 3 groups were formed: in the main group (OG), patients received prevention of PN by using OT and antihypoxant limontar; in the comparison group (GS), only limontar; in the control group (KG), pregnant women did not receive prevention of PN. All patients observed before and after PN prevention were examined for placental lactogen and estriol, ultrasound of the fetoplacental complex (FPC), Doppler examination of the uterine blood fl ow and ultrasound examination of the placenta structure, and morphological examination of the placenta. Results. Based on identifi ed pathogenetic mechanisms of the disorders in the system “mother — placenta — fetus” are defined by a high clinical effi cacy of combined pharmaco-ozone therapy (CT) in the prevention of PN in pregnant women at risk, which was manifested by the lack of progression of PN, whereas in GS, where patients received only pharmacotherapy with limontar, progression was noted in 31,8 % of cases, in KG, where there was no prevention, is 56 %. Conclusion. In the present study, the positive effect of OT and antihypoxant limontar on the processes of microcirculation, metabolism, and adaptation of the body, which provides a signifi cant reduction in the frequency of pregnancy complications, increasing the adaptive capabilities of the fetus and improving perinatal outcomes.


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