Complex pharmaco-ozone therapy in the prevention of placental insufficiency in high-risk pregnancy

2020 ◽  
pp. 19-27
Author(s):  
L. V. Tsallagova ◽  
L. V. Maisuradze ◽  
S. V. Sagkaeva ◽  
T. I. Tsidaeva
Keyword(s):  
High Risk ◽  
Pregnant Women ◽  
The Body ◽  
High Risk Pregnancy ◽  
Placental Lactogen ◽  
Control Group ◽  
Ozone Therapy ◽  
Morphological Examination ◽  
Adaptive Capabilities ◽  
Risk Pregnancy

Summary. Purpose of research. Development of a method for prevention of placental insuffi ciency (PN) in high-risk pregnancy in women of the Republic of North Ossetia-Alania (RSO-A) with the complex use of antihypoxant limontar and ozone therapy (OT). Material and methods. Observations were made of 75 pregnant residents of RSO-A with diagnosed PN, whose average age was 32,6 ± 8,14 years. Using a simple randomization method, 3 groups were formed: in the main group (OG), patients received prevention of PN by using OT and antihypoxant limontar; in the comparison group (GS), only limontar; in the control group (KG), pregnant women did not receive prevention of PN. All patients observed before and after PN prevention were examined for placental lactogen and estriol, ultrasound of the fetoplacental complex (FPC), Doppler examination of the uterine blood fl ow and ultrasound examination of the placenta structure, and morphological examination of the placenta. Results. Based on identifi ed pathogenetic mechanisms of the disorders in the system “mother — placenta — fetus” are defined by a high clinical effi cacy of combined pharmaco-ozone therapy (CT) in the prevention of PN in pregnant women at risk, which was manifested by the lack of progression of PN, whereas in GS, where patients received only pharmacotherapy with limontar, progression was noted in 31,8 % of cases, in KG, where there was no prevention, is 56 %. Conclusion. In the present study, the positive effect of OT and antihypoxant limontar on the processes of microcirculation, metabolism, and adaptation of the body, which provides a signifi cant reduction in the frequency of pregnancy complications, increasing the adaptive capabilities of the fetus and improving perinatal outcomes.

scholarly journals Dapatkah Kelas Ibu Hamil Model Virtual Meningkatkan Praktik Pencegahan Risiko Tinggi Kehamilan ?

2020 ◽  
Vol 30 (1) ◽  
pp. 1-14
Author(s):  
Ayun Sriatmi ◽  
Sri Suwitri ◽  
Zahroh Shaluhiyah ◽  
Sri Achadi Nugraheni
Keyword(s):  
High Risk ◽  
Pregnant Women ◽  
Mixed Model ◽  
Linear Mixed Model ◽  
Intervention Group ◽  
High Risk Pregnancy ◽  
Control Group ◽  
Control Approach ◽  
Risk Pregnancy ◽  
Quasi Experimental

Abstract The inability of pregnant women to identify and recognize danger signs of pregnancy indicates the lack of knowledge, attitudes and perceptions of mothers about healthy pregnancies which has an impact on the low practices of prevention of high risk of pregnancy. Pregnant Women Class Program (KIH) which is held is not optimal because of the low presence of pregnant women for various reasons. The aim of study to determine the effect of the KIH-Virtual model on the practice of preventing high risk of pregnancy. This is a quasi-experimental study with case-control approach. The population is pregnant women in Semarang City. The total sample was 60 mothers for the intervention group and 61 mothers for control group. The independent variable is KIH-Virtual intervention and dependent variable is the practice of preventing high risk pregnancy (covering 7 dimensions). Data collection through interviews and observations with four times measurements (pretest, posttest 1,2,3). Partial analysis using independent-T test and Paired test. Simultaneous analysis with Linear-Mixed-Model. Statistically, there were differences in the practice of preventing high risk pregnancy between intervention groups and control at the last measurement (p<0.05). Although both groups experienced an increase in scores at each measurement stage, it was evident in the intervention group that the increase was higher for all dimensions of practice. The highest increase in the effect of interventions on communication and collaboration practices was followed by health status monitoring practices. Daily self-care practices and lifestyle practices are the dimensions with the lowest intervention effect. Virtual-KIH influences the practice of pregnant women in the prevention of high risk of pregnancy and is able to improve the practice better than conventional models that have been underway. Abstrak  Ketidakmampuan ibu hamil mengidentifikasi dan mengenali tanda bahaya kehamilan mengindikasikan rendahnya pengetahuan, sikap dan persepsi ibu tentang kehamilan sehat, yang berdampak pada rendahnya praktik pencegahan risiko tinggi kehamilan. Program Kelas Ibu Hamil (KIH) yang diselenggarakan belum optimal karena terkendala rendahnya kehadiran ibu hamil dengan berbagai alasannya. Tujuan penelitian menganalisis pengaruh model KIH Virtual terhadap praktik pencegahan risiko tinggi kehamilan. Penelitian ini merupakan penelitian quasi experimental dengan pendekatan kasus-kontrol. Populasi adalah ibu hamil di Kota Semarang. Jumlah sampel 60 ibu untuk kelompok intervensi dan 61 ibu untuk kelompok kontrol. Variabel bebas yaitu intervensi KIH Virtual dan variabel terikatnya yaitu praktik pencegahan risiko tinggi kehamilan (meliputi 7 dimensi). Pengumpulan data melalui wawancara dan observasi dengan 4 kali pengukuran (pretest, posttest-1,2,3). Analisis parsial menggunakan uji beda independen dan berpasangan. Analisis simultan dengan Linear-Mixed-Model. Secara statistik ada perbedaan praktik pencegahan risiko tinggi kehamilan antara kelompok intervensi dengan kontrol pada pengukuran terakhir (p<0,05). Meski kedua kelompok mengalami peningkatan skor pada setiap tahap pengukuran, namun terbukti pada kelompok intervensi peningkatannya lebih tinggi untuk semua dimensi praktik. Peningkatan tertinggi efek intervensi pada praktik komunikasi dan kerjasama, diikuti praktik pemantauan status kesehatan. Praktik perawatan diri sehari-hari dan praktik gaya hidup merupakan dimensi praktik dengan efek intervensi terendah. KIH Virtual memengaruhi praktik ibu hamil dalam pencegahan risiko tinggi kehamilan dan mampu meningkatkan praktik tersebut dengan lebih baik dibandingkan model konvensional yang selama ini berlangsung.  

scholarly journals EFFECTIVENESS OF THE ONE NURSING STUDENT ONE CLIENT ASSISTANCE IN REDUCING HIGH-RISK PREGNANCY

2020 ◽  
Vol 4 (2) ◽  
Author(s):  
Tutik Setyowati ◽  
Erni Nuryan ◽  
Suharto . ◽  
Ismi Rajiani
Keyword(s):  
High Risk ◽  
Pregnant Women ◽  
Nursing Student ◽  
High Risk Pregnancy ◽  
Control Group ◽  
Urine Protein ◽  
Pregnancy Risk ◽  
Control Group Design ◽  
Risk Pregnancy ◽  
Positive Urine

Background: This research aimed to identify the effectiveness of One Nursing Student One Client (OSOC) Assistance in decreasing high-risk pregnancy as an effort to   accelerate the decline in maternal and infant mortality rates.Methods: The research design employed the post test-only control group design method, where the high-risk pregnant women are accompanied by one student one client. After supervision has been completed, the results were then compared with the control group that has been given high-risk leaflet prevention for pregnant women. Mann Whitney Test is used to test the difference statistically.Results: The results of high-risk statistical analysis of hypertension obtained results p = 0.000 (P <0.05), anemia p = 0.001 (P <0.05), swollen extremity p = 0.040 (P <0.05) which means there is   a very significant different average value of high-risk pregnancy between the control group and the experimental group. This indicates that OSOC counseling is effective in reducing high-risk pregnancies of positive urine protein to negative urine protein in Blora City Community Health Center compared with leaflets to control groups. Further, counseling at high risk of swollen extremity was obtained p = 0. 114 (P> 0.05) which mean there was no difference of the mean value of high pregnancy risk of swollen extremity between the control and experiment group.Conclusion: One nursing student one client assistance is effective in reducing high-risk of the third trimester pregnancy women suffering from hypertension, anemia and positive urine proteins. K eywords: mentoring one nursing student one client, high-risk pregnancy

scholarly journals Urinary Nephrin and Podocalyxin Levels as Predictors of Pre-eclampsia in High-Risk Pregnant Women

Folia Medica ◽  
2021 ◽  
Vol 63 (6) ◽  
pp. 948-957
Author(s):  
Irena Kostovska ◽  
Katerina Tosheska Trajkovska ◽  
Ognen Kostovski ◽  
Danica Labudovic
Keyword(s):  
High Risk ◽  
Pregnant Women ◽  
Gestational Age ◽  
High Risk Pregnancy ◽  
Renal Diseases ◽  
Control Group ◽  
Inclusion Criteria ◽  
Risk Pregnancy ◽  
Significant Difference ◽  
History Of

Introduction: Pre-eclampsia (PE) is characterized by new-onset hypertension and proteinuria. Damage of podocyte cells has been reported in pre-eclamptic women, thus podocyte specific proteins such as nephrin and podocalyxin could be useful biomarkers in PE. Aim: To investigate the role of urinary nephrin (u-nephrin) and urinary podocalyxin (u-PDX) levels in predicting PE in women with a high-risk pregnancy. Materials and methods: We included 101 pregnant women in this study and allocated them into three groups: group 1 included pregnant women at high risk of developing PE (n=41), group 2 - pregnant women with PE (n=30), and group 3 was the controls including healthy pregnant women (n=30). The inclusion criteria for women with PE were de novo hypertension >140/90 mm Hg, proteinuria >300 mg/24 hours, and presence of edema after 20 weeks of gestation, while the exclusion criteria were a history of renal diseases and pregnant women younger than 18. Inclusion criteria for the group of women with a high-risk pregnancy was gestational week >15, a history of PE in a previous pregnancy, pre-existing diabetes type 1 or 2, pre-existing hypertension, multiple gestations, prior placental abruption, obesity women, nulliparity, maternal age >35 years, and a family history of PE. The study was conducted from March 2016 to May 2017 in the Medical Faculty at the Institute of Medical and Experimental Biochemistry in Skopje. Urine samples were used to measure the nephrin and podocalyxin levels using immunoenzyme assay, creatinine and microalbumin. Blood samples were collected for biochemical analyses. Results: U-nephrin levels were elevated in 96.7% of women with PE, and 73% of women with a high-risk pregnancy. U-PDX levels were elevated in 63% of the women with PE and 100% of the women with a high-risk pregnancy. U-nephrin and u-PDX levels were significantly increased in women with a high-risk pregnancy and women with PE compared with a control group (p<0.001). A significant difference was found between the subgroups of pregnant women classified according to gestational age in their u-nephrin and u-PDX levels. There was a significant positive correlation between the levels of both markers and glomerular filtration rate, and significant negative correlation between the levels of both markers and gestational age. ROC analysis revealed that the cut-off value of 304.6 ng/ml of u-nephrin had a sensitivity (Se) of 96.7%, specificity (Sp) of 96.7% (for both Se and Sp 95% confidence interval (CI) 82.8-99.9), while the cut-off value of 59.5 ng/ml of u-PDX had a sensitivity of 100% and Sp of 93.3% (Se - 95% CI 88.4-100, Sp - 95% CI 77.9-99.2), in distinguishing women with PE and healthy pregnancies. Both markers showed excellent clinical utility (CUI&ge;0.81), for u-nephrin (CUI+ and CUI&minus; is 0.934), for u-PDX (CUI+ is 0.938; CUI&minus; is 0.933). Conclusions: U-nephrin and U-PDX levels could be useful as predictors of PE in women with a high-risk pregnancy.

scholarly journals Effect of Rectal Misoprostol to Blood Loss at High Risk Pregnancy

2017 ◽  
pp. 187
Author(s):  
Daniel Liando Daniel Liando ◽  
IMS Murah Manoe ◽  
Eddy R Moeljono
Keyword(s):  
Treatment Group ◽  
High Risk ◽  
Blood Loss ◽  
Pregnant Women ◽  
Standard Procedure ◽  
High Risk Pregnancy ◽  
Control Group ◽  
Normal Delivery ◽  
Risk Criteria ◽  
Risk Pregnancy

Objective: To compare the effectiveness of rectal misoprostol administration to the amount of blood loss in 4th stage of labor at high risk pregnancy. Method: We recruited all pregnant women with high risk criteria including anemia, age  35 years old, or the number of pregnancies  4. Women would deliver appropriate to standard procedure of normal delivery. After that, we gave 400-mcg tablet of misoprostol rectally in treatment group. To count the amount of blood loss during 4th stage of labor, we put the underpad. Result: The amount of blood loss in 4th stage of labor in the treatment group was 201.1 (SD 80.3) ml less than the control group (285.9 (SD 93.2) ml). The result showed that the administration of 400-mcg misoprostol tablet rectally immediately after the birth of the placenta at high risk pregnancy impacted significantly to reduce the amount of blood loss in 4th stage of labor (p

scholarly journals Vulnerability of high-risk pregnancy in the perception of pregnant women and their families

Rev Rene ◽  
2019 ◽  
Vol 20 ◽  
pp. e40207
Author(s):  
Viviane Cazetta de Lima Vieira ◽  
Mayckel da Silva Barreto ◽  
Verônica Francisqueti Marquete ◽  
Rebeca Rosa de Souza ◽  
Mayara Maria Johann Batista Fischer ◽  
...  
Keyword(s):  
High Risk ◽  
Pregnant Women ◽  
High Risk Pregnancy ◽  
Risk Pregnancy

The Effect of Lullaby Intervention on Anxiety and Prenatal Attachment in Women with High-Risk Pregnancy: A Randomized Controlled Study

2021 ◽  
pp. 1-9
Author(s):  
Nazlı Baltacı ◽  
Mürüvvet Başer
Keyword(s):  
High Risk ◽  
Intervention Group ◽  
Group Versus ◽  
Mean Difference ◽  
High Risk Pregnancy ◽  
Controlled Study ◽  
Control Group ◽  
Prenatal Attachment ◽  
Randomized Controlled ◽  
Risk Pregnancy

<b><i>Background:</i></b> Women with high-risk pregnancy experience anxiety and low mother-fetal attachment when faced with signs of danger and health problems. This study aimed to investigate the effects of lullaby intervention on anxiety and prenatal attachment in women with high-risk pregnancy. <b><i>Materials and Methods:</i></b> This randomized controlled trial was conducted in the perinatology clinic of a state maternity hospital in Turkey. Seventy-six women with high-risk pregnancy were included. The intervention group listened to lullabies for 20 min once a day, and accompanied by lullabies touched their abdomen and thought about their babies, but the control group did not. Data were collected using the Pregnant Information Form, the State Anxiety Inventory, and the Prenatal Attachment Inventory. <b><i>Results:</i></b> Baseline anxiety did not differ in the intervention versus control group (47.83 ± 10.74 vs. 44.10 ± 8.08, mean difference 3.73 [95% Cl –1.18 to 8.64], <i>p</i> = 0.13), but after the 2nd day lullaby intervention anxiety was lower in the intervention group versus control group (33.66 ± 9.32 vs. 43.06 ± 8.10, mean difference –9.40 [95% Cl –13.91 to –4.88], <i>p</i> &#x3c; 0.01). Baseline prenatal attachment did not differ in the intervention versus control group (56.03 ± 10.71 vs. 53.86 ± 9.98, mean difference 2.16 [95% Cl –3.18 to 7.51], <i>p</i> = 0.42), but after the 2nd day lullaby intervention prenatal attachment was higher in the intervention group versus control group (66.70 ± 7.60 vs. 54.36 ± 9.52, mean difference 12.33 [95% Cl 7.87 to 16.78], <i>p</i> &#x3c; 0.01). In the within-group analysis the intervention group had lower anxiety and better prenatal attachment (<i>p</i> &#x3c; 0.01), but not in the control group (<i>p</i> &#x3e; 0.05). <b><i>Conclusion:</i></b> Lullaby intervention can play an effective role in reducing anxiety and improving prenatal attachment. The use of this integrative, noninvasive, non-pharmacologic, time-efficient, and natural intervention is suggested in the care of pregnant women.

The experiences of maternity in front of hospitalization in high risk pregnances

2020 ◽  
Vol 30 (Supplement_5) ◽  
Author(s):  
M Ciciliotti da Silva ◽  
B Heintze Ferreira ◽  
D Fraga Santos ◽  
F Fernandes ◽  
Bersot Magalhães ◽  
...  
Keyword(s):  
Public Health ◽  
High Risk ◽  
Pregnant Women ◽  
Maternity Hospital ◽  
High Risk Pregnancy ◽  
Structured Interviews ◽  
The Public ◽  
Prenatal Consultation ◽  
Risk Pregnancy ◽  
Specialized Care

Abstract Introduction The pregnancy-puerperal cycle is defined as a moment that involves physical, psychological and social changes. There are pregnancies that require specialized care and attention due to the presence of risk factors that may be prior to pregnancy and / or that may be associated with the pregnancy condition itself, which characterize them as high-risk pregnancies. Currently, prenatal care with risk stratification is the main care strategy for pregnant women, once the risk classification is identified, it is possible to promote interventions according to the health needs of each pregnant woman. For this, the risk assessment is carried out at each prenatal consultation, so that, depending on the course of pregnancy, hospitalization becomes necessary. The diagnosis of high-risk pregnancies accompanied by hospitalization has impacts on the woman's life, such as loss of autonomy, a sense of failure and the incidence of greater care and interventions by the health team and the family that can configure practices to control their bodies. Objective This work aims to identify the hospitalization process during high-risk pregnancy as a space for the production of projects, resistance and protagonism through the protocols and regulations that configure the hospital context. Methodology This is an exploratory analysis of a qualitative approach in public health. A reference maternity hospital in high-risk pregnancy located in a teaching hospital in Greater Vitória was chosen. It will be used to define sampling for convenience. The data will be collected through semi-structured interviews and on-site observations by the researcher. The data analysis methodology used will be content analysis. Expected Results It is expected to understand the various practices of protagonism and resistance that permeate the care of hospitalized pregnant women. Key messages This work has an impact on the improvement of the maternal and child care network of the public health system in Brazil. This work allows to evaluate the quality of the assistance provided in the public maternity.

scholarly journals Risk status of pregnant women in rural areas of Belagavi: a cross sectional study

2019 ◽  
Vol 6 (6) ◽  
pp. 2350
Author(s):  
Katherine J. Bernard ◽  
Sulakshana Baliga
Keyword(s):  
High Risk ◽  
Pregnant Women ◽  
Rural Areas ◽  
Cross Sectional Study ◽  
High Risk Pregnancy ◽  
Cross Sectional ◽  
Risk Status ◽  
Factors Associated ◽  
Risk Pregnancy ◽  
Status Assessment

Background: ‘High-risk’ pregnancies account for a significant proportion of perinatal morbidity and mortality worldwide. Simple prenatal scoring systems can be used to assess risk status of pregnancy and inform subsequent management. Their use in rural areas and low-resource settings could be of particular benefit. This study employed pregnancy risk status assessment in one such area of rural India. The objectives of the study were to estimate the prevalence of low, moderate and high-risk pregnancy among women in a rural area of Belagavi and to identify factors associated with high-risk pregnancy status.Methods: This community-based cross-sectional study was undertaken among 105 pregnant women of all trimesters presenting to antenatal clinics in the Kinaye area of Belagavi, Karnataka, during July 2018. Information on risk factors and socio-demographic details were collected using a questionnaire, and individual risk scores calculated through a scoring system. This was used to estimate prevalence of low, moderate and high-risk status among participants, and subsequently compared against selected variables to identify factors associated with high risk pregnancy status.Results: Prevalence of high-risk pregnancy among participants was 31.4%, moderate-risk 30.5%, low-risk 29.5% and ‘no risk’ 8.6%. Maternal undernutrition was an important factor associated with high-risk pregnancy.Conclusions: This study highlights the need for early identification and appropriate management of such cases, in order to prevent adverse perinatal outcomes. The prenatal scoring system used in this study offers a simple method for risk status assessment in pregnant women of all trimesters, suited for use in antenatal clinics in rural areas of India.

scholarly journals IBM PENDAMPINGAN IBU HAMIL RESIKO TINGGI OLEH KADER POSYANDU DI WILAYAH PUSKESMAS PURWOYOSO

2017 ◽  
Vol 8 (2) ◽  
Author(s):  
Chusnul Zulaika ◽  
Dewi Sari R ◽  
Mirtaria K
Keyword(s):  
High Risk ◽  
Pregnant Women ◽  
Good Health ◽  
High Risk Pregnancy ◽  
Maternal Deaths ◽  
Central Java ◽  
Risk Pregnancy ◽  
Husband Support ◽  
Alternative Solutions ◽  
Central Java Province

Kehamilan normal bisa memiliki risiko, semua ibu hamil  perlu perawatan agar ibu dan janin tetap dalam keadaan sehat. Sedangkan kehamilan yang resiko tinggi akan menghadapi berbagai permasalahan yang dapat mengganggu proses persalinan. Kehamilan dengan masalah dikelompokkan kehamilan risiko tinggi yaitu keadaan yang dapat mempengaruhi optimalisasi ibu maupun janin (Manuaba,2003). Kehamilan risiko tinggi adalah kehamilan dengan satu lebih  faktor risiko baik ibu maupun janinnya yang memberi dampak kurang menguntungkan baik ibu maupun janinnya (Rochjati, 2003). Apabila setiap abnormalitas dicurigai berdasarkan atas riwayat atau pemeriksaan fisik, maka pasien dirujuk ke pemeriksa dengan keahlian dalam ultrasonografi (Tucker, 2004).Di Provinsi Jawa Tengah pada tahun 2015 terdapat 619 kasus kematian ibu. Kota Semarang menduduki peringkat ke 2 setelah kabupaten Brebes dengan jumlah kematian ibu di Kota Semarang  terdapat 35 kasus. Di Puskesmas Purwoyoso pada tahun 2015 terdapat 1 kasus kematian ibu. Sedangkan jumlah ibu hamil resiko tinggi di Puskesmas Purwoyoso pada tahun 2015 terdapat 595 ibu hamil.Untuk mencari alternatif solusi pemecahan masalah di atas, maka diadakan peningkatan pengetahuan tentang pendampingan ibu hamil resiko tinggi di Puskesmas Purwoyoso dengan tujuan untuk meningkatkan pengetahuan para kader tentang kehamilan resiko tinggi. Setelah dilakukan penyuluhan didapatkan hasil pengetahuan dan kesadaran para kader untuk melaksanakan pendampingan meningkat.Diharapkan setelah dilakukan pengabdian penulis menyarankan para kader, keluarga dan suami mendukung ibu hamil untuk melakukan pemeriksaan kehamilan di bidan ataupun di puskesmas.Kata kunci        : IBM ; Kader ; Pendampingan ibu hamil resiko tinggi IBM HIGH RISK PREGNANCY ASSISTANCE BY POSYANDU CARDER IN PURWOYOSO PUSKESMAS REGIONNormal pregnancy can have a risk, all pregnant women need care so that mother and fetus remain in good health. While high-risk pregnancies will face a variety of problems that can interfere with labor. Pregnancy with the problem grouped high-risk pregnancies is a condition that can affect the optimization of mother and fetus (Manuaba, 2003). A high-risk pregnancy is a pregnancy with one more risk factor for both mother and fetus that has an adverse impact on both the mother and the fetus (Rochjati, 2003). If any abnormality is suspected based on a history or physical examination, the patient is referred to an examiner with expertise in ultrasonography (Tucker, 2004).In Central Java Province in 2015 there were 619 cases of maternal deaths. Semarang City is ranked second after Brebes district with the number of maternal deaths in Semarang city there are 35 cases. At Puskesmas Purwoyoso in 2015 there is 1 case of maternal mortality. While the number of high risk pregnant women at Purwoyoso Puskesmas in 2015 there are 595 pregnant women.To find alternative solutions to the above solutions, there is an increased knowledge about high risk pregnant women in Purwoyoso Puskesmas in order to increase the knowledge of cadres about high risk pregnancy. After the counseling obtained the knowledge and awareness of the cadres to carry out mentoring increased.It is hoped that after the dedication of the writer suggest that cadres, family and husband support pregnant mother to conduct pregnancy examination in midwife or at puskesmasKey words             : IBM; Cadres; High risk pregnancy assistance

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