scholarly journals A rare case report of gestational trophoblastic disease in peri menopausal women

2020 ◽  
Vol 9 (11) ◽  
pp. 4716
Author(s):  
Nagashree U. ◽  
Wahida Suresh
Keyword(s):  
Early Recognition ◽  
Gestational Trophoblastic Disease ◽  
Reproductive Age ◽  
Trophoblastic Disease ◽  
Menopausal Women ◽  
Rare Case Report ◽  
Abnormal Bleeding ◽  
Post Menopausal ◽  
Reproductive Age Group

Benign gestational trophoblastic disease (GTD) generally occurs in reproductive age group women; but is extremely rare in peri and post-menopausal women. We report a case of molar pregnancy in a 48-year-old lady with complaints of bleeding per vaginum with severe pain abdomen. The intention was to highlight the need to include GTD as a possible cause of abnormal bleeding per vaginum in peri and post-menopausal women. So early diagnosis and management with proper follow up is possible. It stresses the need for early recognition to avoid high malignant sequelae.

scholarly journals Twin pregnancy with complete hydatiform mole and coexisting live fetus: A rare case report

2019 ◽  
pp. 31-34
Author(s):  
Swati Agrawal ◽  
Kiran Aggarwal ◽  
Anjali Singh ◽  
Khushbu Saha ◽  
Amrita Mishra ◽  
...  
Keyword(s):  
Rare Case ◽  
Twin Pregnancy ◽  
Gestational Trophoblastic Disease ◽  
Rare Entity ◽  
Trophoblastic Disease ◽  
Complete Mole ◽  
Beta Hcg ◽  
Rare Case Report ◽  
Live Fetus

Twin pregnancy with one live fetus and one complete mole, also known as CMCF i.e. complete molar pregnancy with coexisting live fetus is a rare entity in obstetrics. This combination is associated with increased incidences of spontaneous abortions, vaginal bleeding, prematurity, intrauterine demise, pre-eclampsia, uterine ruptures, theca lutein cysts, persistent gestational trophoblastic disease. We report a rare case of a 24-year-old patient with CMCF at 14 weeks of gestation. After confirming the diagnosis, ruling out malignancy and proper counselling, decision was taken to continue her pregnancy. However, the patient had spontaneous abortion at 15 weeks of gestation. Her serum beta Hcg has shown a decreasing trend in her follow up visits with no signs suggestive of persistent gestational trophoblastic disease.

scholarly journals ASYMPTOMATIC LABIAL FUSION DIAGNOSED DURING LABOUR -(A CASE REPORT)

2020 ◽  
pp. 35-36
Author(s):  
Anshu Baser ◽  
Bhoomika Jain ◽  
Sushil Kumar
Keyword(s):  
Reproductive Age ◽  
Age Group ◽  
Women Of Reproductive Age ◽  
Labia Minora ◽  
Labial Fusion ◽  
Menopausal Women ◽  
History Of ◽  
Post Menopausal ◽  
Prepubertal Age ◽  
Reproductive Age Group

Labial fusion is when the labia minora of the vulva fuse together. This most commonly occurs in prepubertal age group(0.6%-5%).(1) This condition rarely occurs in adults and even in adults it is seen in post menopausal women and may result in urinary incontinence.(2) It is extremely rare in women of reproductive age group and only a few cases have been reported so far.(3) We here report a case of a 25 year old female with asymptomatic labial fusion with no history of voiding difficulty, dyspareunia who presented to us at term in labour.

scholarly journals A Rare Case of Metastatic Choriocarcinoma of Lung Origin

2017 ◽  
Vol 2017 ◽  
pp. 1-4 ◽  
Author(s):  
Parth Rali ◽  
Jianwu Xie ◽  
Grishma Rali ◽  
Mayur Rali ◽  
Jan Silverman ◽  
...  
Keyword(s):  
Rare Case ◽  
Gestational Trophoblastic Disease ◽  
Primary Site ◽  
Reproductive Age ◽  
Gynecologic Malignancy ◽  
Women Of Reproductive Age ◽  
Trophoblastic Disease ◽  
Treatment Prognosis ◽  
Pathological Confirmation

Choriocarcinoma is part of the spectrum of gestational trophoblastic disease that occurs in women of reproductive age. Although the most common metastatic site of choriocarcinoma is the lung, primary pulmonary choriocarcinoma is rare. To diagnose primary pulmonary choriocarcinoma, the patient should have no previous gynecologic malignancy, have elevated human chorionic gonadotropin, and have pathological confirmation of the disease excluding gonadal primary site of the tumor. Due to the paucity of data, there are no guidelines for treatment. Prognosis of this malignancy is extremely poor. We report a rare case of metastatic primary lung choriocarcinoma in a 69-year-old postmenopausal woman who was treated with combination of surgery, chemotherapy, and radiation. The patient had a good outcome and is doing well after 1-year follow-up.

scholarly journals Borderline Papillary Serous Tumour of the Peritoneum

2018 ◽  
Vol 8 (2) ◽  
pp. 69-72 ◽  
Author(s):  
Md Mustafizur Rahman ◽  
Md Abul Kalam Azad ◽  
Nadim Ahmed ◽  
Nazmin Rahman ◽  
Muhammad Raquib Hussain
Keyword(s):  
Ovarian Tumour ◽  
Reproductive Age ◽  
Borderline Tumour ◽  
Medical College ◽  
Menopausal Women ◽  
Rare Lesion ◽  
Ovarian Pathology ◽  
Post Menopausal ◽  
Upper Abdomen ◽  
Reproductive Age Group

Primary borderline serous peritoneal tumour is a rare lesion found in the absence of ovarian pathology, in the presence of minimal ovarian involvement or in association with benign ovarian tumour. It is thought to arise from the mullerian system, which is embryologically derived from the coelomic and sub-coelomic mesenchyme, and therefore shares histologic similarities with ovarian serous tumours. Such tumours are mostly found in women of reproductive age group although cases have been reported for post-menopausal women. We report a case of a primary peritoneal borderline tumour diagnosed in a middle aged patient with lump and pain the upper abdomen in Shaheed Suhrawardy Medical College & Hospital.J Shaheed Suhrawardy Med Coll, December 2016, Vol.8(2); 69-72

scholarly journals A prospective study of gestational trophoblastic disease profile with special reference to mortality and pregnancy outcome after successful management of the same

2019 ◽  
Vol 6 (10) ◽  
pp. 4363
Author(s):  
Abantika Bhattacharya ◽  
Tanmay Kanti Panja ◽  
Amiya Bhattacharya ◽  
Baijayanti Baur ◽  
Kishore P. Madhwani
Keyword(s):  
Pregnancy Outcome ◽  
Fetal Tissue ◽  
Gestational Trophoblastic Disease ◽  
Reproductive Age ◽  
Molar Pregnancy ◽  
Successful Management ◽  
Abnormal Growth ◽  
Trophoblastic Disease ◽  
A Prospective Study ◽  
Reproductive Age Group

Background: Gestational trophoblastic disease (GTD) is a group of rare tumors that involve abnormal growth of cells inside a woman's uterus. GTD does not develop from cells of the uterus like cervical cancer or endometrial (uterine lining) cancer do. Instead, these tumors start in the cells that would normally develop into the placenta during pregnancy. GTD is unique because the maternal lesions arise from the fetal tissue as a molar pregnancy. All forms of GTD can be treated. In most cases the treatment produces a complete cure. The study was conducted to assess the various presenting features of GTD and factors associated with it.Methods: It was an observational hospital based prospective epidemiological study. Complete enumeration technique was followed and a total of 305 female patients were included in the sample. A pre-designed and pre-tested interview schedule was used to record different information and detailed history.Results: Of the 305 patients studied, 67.2% were diagnosed with H. mole, 23% patients were diagnosed with gestational trophoblastic tumor, among them 4.9% had choriocarcinoma. Majority were primigravida and of blood group O type. Pregnancy outcome after successful management of GTD were 63.3% had full term pregnancy, 20% cases had repeat molar pregnancy, 10% had spontaneous abortion while 6.7% (2/30) had pre term delivery.Conclusions: Gestational trophoblastic disease is seen most commonly in reproductive age group. If it is not diagnosed on time it can be fatal. This is a highly curable tumor even in the presence of distant metastasis.

Spectrum of Pathological Lesions in Uterine Specimens with Focus on Gestational Trophoblastic Disease in Karachi

2020 ◽  
Keyword(s):  
Hydatidiform Mole ◽  
Endometrial Stromal Sarcoma ◽  
Gestational Trophoblastic Disease ◽  
Cross Sectional Study ◽  
Reproductive Age ◽  
P Value ◽  
Cross Sectional ◽  
Endometrial Polyps ◽  
Trophoblastic Disease ◽  
Proliferative Endometrium

Background: The most common benign pathological lesion in women of reproductive age is uterine leiomyoma. Gestational trophoblastic disease includes tumors and tumor like lesions originating from trophoblastic tissue. The aim of this study was to find the spectrum of molar pregnancy and uterine pathologies focusing on gestational trophoblastic disease as no study has been done in the past few years. Methods: Endometrial and uterine specimens of patients (n=436) between the ages of 15-65 years were collected from a private hospital in Karachi from December 2018 to December 2019. This cross-sectional study was carried out by pathological diagnosis of patients’ samples under light microscopy using hematoxylin and eosin staining. Stratification was done about age and nature of specimen to control the effect modifiers. The post stratification Chi square test was applied and p value <0.05 was considered significant. Results: Mean age of the patients was 36.1 years ±7.8. Total 436 uterine biopsies included 260(59.6%) hysterectomies, 56(12.8%) endometrial curetting’s, 117(26.8%) evacuation specimens and 3(0.7%) polypectomies. Common pathologies included 124(28.4%) leiomyomas, 61(14%) proliferative endometrium, 52(11.9%) adenomyosis and 32(7.3%) endometrial polyps. Gestational trophoblastic disease was seen in 9(2.06%). Seven (87.5%) were partial hydatidiform moles, one (12.5%) exaggerated placental site reaction and one choriocarcinoma. Mole was common between 26-30 years with mean age of 27.2 years and prevalence was 6/100 abortions. Conclusion: Leiomyoma was the commonest (28.4%) uterine pathology followed by proliferative endometrium (14.5%). However, endometrial stromal sarcoma and endometriosis were found 0.2% each. High prevalence of mole was seen in this study. Partial mole was most common and choriocarcinoma was least common. Keywords: Hydatidiform Mole; Pathology; Prevalence.

scholarly journals Large cervical fibroid: a rare case report

2019 ◽  
Vol 8 (8) ◽  
pp. 3414
Author(s):  
Sunanda N.
Keyword(s):  
Uterine Fibroids ◽  
Total Abdominal Hysterectomy ◽  
Large Mass ◽  
Abdominal Hysterectomy ◽  
Reproductive Age ◽  
Pelvic Tumors ◽  
Rare Case Report ◽  
Tender Mass ◽  
Restricted Mobility ◽  
Reproductive Age Group

Although leiomyomas are the most common pelvic tumors presenting in the reproductive age group, cervical fibroids are rare accounting for 2% of all uterine fibroids. We report a case of 40 year old lady presenting with a firm, non-tender mass of 22-24 weeks size pregnant uterus with restricted mobility. Laparotomy showed a large mass arising from the anterior lip of cervix, with a small uterus pushed posteriorly. Enucleation followed by total abdominal hysterectomy was done. Large cervical fibroids are rare, presenting with surgical difficulties. Careful dissection by expert hands is needed in the management of such cases. 

A Study of Molar Pregnancy at Low Resource Settings of Tertiary Care Hospital Sindh

2021 ◽  
Vol 15 (7) ◽  
pp. 1547-1549
Author(s):  
Sabahat Fatima ◽  
A. G.ul Shaikh ◽  
Tahmina Mahar ◽  
Hameed-Ur-Rehman Bozdar ◽  
Sameena Memon ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Body Mass ◽  
Economic Status ◽  
Gestational Trophoblastic Disease ◽  
Common Symptom ◽  
Care Hospital ◽  
Molar Pregnancy ◽  
Socio Economic Status ◽  
Trophoblastic Disease

Aim: To determine the epidemiological factors/characteristics and clinical presentation of molar pregnancy Study design: Qualitative observational / retrospective study Place and duration: Department of Obstetrics and Gynaecology Unit-II, Ghulam Muhammad Mahar Medical College Sukkur from 1st January 2016 to 31st December 2020. Methodology: Forty five diagnosed cases with molar pregnancy and aged between 18-40 years were enrolled. Patient’s details demographics age, body mass index, parity and socio economic status were recorded. The total birth records and gynecological admission for the study period were also collected from the gynaecology and labour room record books case and operational registration data were obtained, descriptive statistics examined . Results: Mean age of the patients was 31.15±7.41 years with mean body mass index 26.16±7.22 kg/m2. Mean gestational age of the patients were 25.62±9.19 weeks. Twenty seven (60%) patients were multiparous and 18 (40%) were primiparous. 30 (66.7%) were illiterate and 15(33.3%) cases were literate. There were 14(31.11%) patients belonged lower class, 18 (40%) patients belonged middle and 13(28.9%) had high socioeconomic status. Twenty nine (64.4%) were from rural area and 16 (35.6%) were from urban area. Five (11.1%) patients had previous history of gestational trophoblastic disease. Abnormal vaginal bleeding was the most common symptom found in 34(75.5%) cases followed by lower abdominal pain found in 30 (66.7%) patients, hyperemesis found in 14(31.1%) and dyspnea in 9 (20%). Thirty six (80%) patients received suction evacuation and 9 (20%) cases referred. Forty one (91.1%) patients were recovered but the rest 4 (8.9%) were lost during follow up. Conclusion: Low/middle socio-economic status, illiteracy and cases from rural areas had multiparous parity was highly effected by molar pregnancy disease and it can be controlled by early diagnose to take regular follow-up by using suction evacuation. Key words: Gestational trophoblastic disease (GTD), Molar pregnancy, Primiparous, Multiparous

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