scholarly journals Septicaemia in pregnancy: a case report

2021 ◽  
Vol 10 (10) ◽  
pp. 4008
Author(s):  
Amrita Jain ◽  
Kaavya Sathyamurthy
Keyword(s):  
Diabetes Mellitus ◽  
Subcutaneous Tissue ◽  
Abdominal Cavity ◽  
Ventilatory Support ◽  
Vascular Occlusion ◽  
Signs And Symptoms ◽  
Deep Fascia ◽  
Skin Defect ◽  
Surgical Infection ◽  
In Pregnancy

Necrotizing fasciitis (NF) is a rare, life-threatening surgical infection in pregnancy with high rates of morbidity and mortality. It is a severe, potentially fatal infectious disease which rapidly extends from the subcutaneous tissue along the superficial and deep fascia causing vascular occlusion, ischemia, and necrosis of tissues. A 30-year-old gravida 2 para1 living 1 woman, at 32 weeks of gestation with previous caesarean section and recently diagnosed diabetes, hypertension was admitted to our hospital with signs and symptoms of severe sepsis with pruritic black lesions over abdomen and perineum. Patient was in a morbid state in our hospital. During clinical examination, fetal heart sound was not localised suggestive of intrauterine fetal demise (IUFD), with ulcerative lesions over abdomen and vulva. Patient was immediately taken for surgical intervention and was suggestive of ruptured uterus with extrusion of fetus in abdominal cavity with cellulitis of abdominal and vulva. During initial laboratory examinations, diabetes mellitus was diagnosed. Patient was kept on ventilatory support and was vitals were stabilised. Multidisciplinary therapy with immediate aggressive surgical debridement of necrotic tissues, multiple antibiotics, and intensive care monitoring was performed successfully. The patient’s postoperative course was uncomplicated and skin defect healed by second intention of healing. The following case emphasized the potential immunosuppressive role of pregnancy state in conjunction with diabetes mellitus in the development of severe necrotizing soft tissue infections.

scholarly journals Necrotizing Fasciitis Complicating Pregnancy: A Case Report and Literature Review

2014 ◽  
Vol 2014 ◽  
pp. 1-4 ◽  
Author(s):  
Marinos Nikolaou ◽  
Petros Zampakis ◽  
Vasiliki Vervita ◽  
Konstantinos Almaloglou ◽  
Georgios Adonakis ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Necrotizing Fasciitis ◽  
Subcutaneous Tissue ◽  
Skin Grafting ◽  
Skin Defect ◽  
Surgical Infection ◽  
Left Lower Extremity ◽  
Split Thickness Skin Grafting ◽  
Necrotizing Soft Tissue Infections ◽  
Magnetic Resonance Imaging Mri

Necrotizing fasciitis is a rare, life-threatening surgical infection in pregnancy with high rates of morbidity and mortality. A 15-year-old primigravid woman, at 28 weeks of gestation with no significant previous medical history, was admitted to our hospital complaining of severe left lower extremity pain and high fever the last 72 hours. During clinical examination, she had a swollen, erythematous and tender to palpation inflamed skin over the medial aspect of the upper thigh without any evidence of injury. Incision drainage was performed immediately and she received broad spectrum antibiotics. During initial laboratory examinations, diabetes mellitus was diagnosed. There was no clinical improvement over the following days. Magnetic resonance imaging (MRI) revealed subcutaneous tissue inflammation and edema of infected tissues confirming the disease entity. Multidisciplinary therapy with immediate aggressive surgical debridement of necrotic tissues, multiple antibiotics, and intensive care monitoring was performed successfully. The patient’s postoperative course was uncomplicated and skin defect was closed with split thickness skin grafting. Our case emphasized the potential immunosuppressive role of pregnancy state in conjunction with diabetes mellitus in the development of severe necrotizing soft tissue infections.

scholarly journals The study of the prognostic outcome of necrotizing fasciitis patients with and without diabetes mellitus

2021 ◽  
Vol 8 (2) ◽  
pp. 563
Author(s):  
Navjot Kaur ◽  
Seema Mittal ◽  
Sudershan Kapoor ◽  
Arun Gupta
Keyword(s):  
Diabetes Mellitus ◽  
Early Diagnosis ◽  
Necrotizing Fasciitis ◽  
Subcutaneous Tissue ◽  
Morbidity And Mortality ◽  
Deep Fascia ◽  
Superficial Fascia ◽  
Cross Sectional ◽  
Prognostic Outcome ◽  
Aggressive Debridement

Background: Necrotizing fasciitis is highly lethal infection. It can be defined as infection of any layers within the soft tissue compartment (dermis, subcutaneous tissue, superficial fascia, deep fascia or muscle). Early diagnosis and management with identification of co morbidities and treating them brings down the morbidity and mortality rate. To make a full assessment of the cause, all patients require a detailed history, examination and, investigations.Methods: This is a cross sectional comparative study of 50 patients having symptoms of necrotizing fasciitis to be divided into two groups of 25 patients each where one group is having diabetes mellitus and other group without diabetes mellitus.Results: Diabetes mellitus patients have more morbidity and mortality in term of more days of hospital stay, rate of amputations and number of debridements. Early diagnosis and early aggressive debridement is the mainstay of management. Aggressive surgical debridement at initial stages of presentation can halt the clinical process and patient can have better prognosis. In neglected diabetic patient’s debridement alone is not sufficient and amputation may be required in some cases.  Conclusions: Early diagnosis and aggressive debridement in necrotizing fasciitis patients results in better outcomes.  

Schistosomal Appendicitis in Pregnancy

Swiss Surgery ◽  
2002 ◽  
Vol 8 (3) ◽  
pp. 121-122 ◽  
Author(s):  
Halkic ◽  
Abdelmoumene ◽  
Gintzburger ◽  
Mosimann
Keyword(s):  
Acute Appendicitis ◽  
Schistosoma Haematobium ◽  
Acute Inflammation ◽  
The Body ◽  
Parasitic Infections ◽  
Common Complication ◽  
Surgical Infection ◽  
High Prevalence ◽  
Potential Challenge ◽  
In Pregnancy

Acute appendicitis is the most common acute surgical infection during pregnancy. Although usually pyogenic in origin, parasitic infections account for a small percentage of cases. Despite the relatively high prevalence of acute appendicitis in our environment, it is not commonly associated with schistosomiasis. We report here the association of pregnancy and appendicitis caused by Schistosoma haematobium. Schistosomiasis is very common complication of pregnancy in hyperendemic areas. Schistosome egg masses can lodge throughout the body and cause acute inflammation of the appendix, liver and spleen. Congestion of pelvic vessels during pregnancy facilitates passage of eggs into the villi and intervillous spaces, causing an inflammatory reaction. Tourism and immigration make this disease a potential challenge for practitioners everywhere.

Toxicity of Diabetes Mellitus in Pregnancy

2009 ◽  
Vol 39 (21) ◽  
pp. 52
Author(s):  
GERALD G. BRIGGS
Keyword(s):  
Diabetes Mellitus ◽  
In Pregnancy

IGFs and IGF-Binding Proteins in Pregnancy and Gestational Diabetes Mellitus

Diabetes ◽  
2018 ◽  
Vol 67 (Supplement 1) ◽  
pp. 1412-P
Author(s):  
KATEřINA ANDERLOVÁ ◽  
PATRIK SIMJAK ◽  
ANNA CINKAJZLOVA ◽  
JANA KLOUCKOVA ◽  
HELENA KRATOCHVILOVA ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Gestational Diabetes ◽  
Gestational Diabetes Mellitus ◽  
Binding Proteins ◽  
Igf Binding Proteins ◽  
Igf Binding ◽  
In Pregnancy

Fetal Brain Activity in Pregnancy of Women with Type 1 Diabetes Mellitus

Diabetes ◽  
2018 ◽  
Vol 67 (Supplement 1) ◽  
pp. 1402-P
Author(s):  
ELLEN FEHLERT ◽  
FRANZISKA SCHLEGER ◽  
KATARZYNA LINDER ◽  
MARTIN HENI ◽  
HANS-ULRICH HAERING ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 1 Diabetes ◽  
Type 1 Diabetes Mellitus ◽  
Brain Activity ◽  
Fetal Brain ◽  
In Pregnancy

Insulin Therapy in Pregnancy Hypertensive Diseases and its Effect on the Offspring and Mother Later in Life

2019 ◽  
Vol 17 (5) ◽  
pp. 455-464 ◽  
Author(s):  
Alfonso Mate ◽  
Antonio J. Blanca ◽  
Rocío Salsoso ◽  
Fernando Toledo ◽  
Pablo Stiefel ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Insulin Resistance ◽  
Polycystic Ovary Syndrome ◽  
Insulin Therapy ◽  
Polycystic Ovary ◽  
Ovary Syndrome ◽  
Insulin Resistant ◽  
Hypertensive Disorders ◽  
The Impact ◽  
In Pregnancy

Pregnancy hypertensive disorders such as Preeclampsia (PE) are strongly correlated with insulin resistance, a condition in which the metabolic handling of D-glucose is deficient. In addition, the impact of preeclampsia is enhanced by other insulin-resistant disorders, including polycystic ovary syndrome and obesity. For this reason, there is a clear association between maternal insulin resistance, polycystic ovary syndrome, obesity and the development of PE. However, whether PE is a consequence or the cause of these disorders is still unclear. Insulin therapy is usually recommended to pregnant women with diabetes mellitus when dietary and lifestyle measures have failed. The advantage of insulin therapy for Gestational Diabetes Mellitus (GDM) patients with hypertension is still controversial; surprisingly, there are no studies in which insulin therapy has been used in patients with hypertension in pregnancy without or with an established GDM. This review is focused on the use of insulin therapy in hypertensive disorders in the pregnancy and its effect on offspring and mother later in life. PubMed and relevant medical databases have been screened for literature covering research in the field especially in the last 5-10 years.

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