scholarly journals The study of clinical and endoscopic spectrum of upper gastrointestinal manifestations in HIV patients

2018 ◽  
Vol 6 (5) ◽  
pp. 1588
Author(s):  
Raman Parashar ◽  
Deepali Kaushik ◽  
Praveen K. Malik
Keyword(s):  
Early Diagnosis ◽  
Opportunistic Infections ◽  
Gastrointestinal Symptoms ◽  
Common Finding ◽  
Hiv Patients ◽  
Upper Gi ◽  
Antral Gastritis ◽  
Gi Symptoms ◽  
Candida Esophagitis ◽  
Upper Gastrointestinal

Background: Opportunistic disorders are the most frequent GI complications of HIV infection and remain a major cause of morbidity and mortality in these patients. These disorders account for high prevalence of upper gastrointestinal symptoms such as dysphagia, odynophagia, retrosternal chest pain, abdominal pain and upper GI bleeding. Hence an attempt is being made to study clinical, endoscopic and biopsy changes in HIV patients with upper GI symptoms which helps us to make early diagnosis of upper GI disorders in HIV patients.Methods: HIV positive patients above 14 yrs diagnosed on the basis of recent NACO criteria having Upper G.I. symptoms, attending OPD of Department of Medicine admitted in Wards. All fifty three patients with upper G.I. symptoms were subjected to detail history, thorough clinical examination, routine and special investigations and Upper G.I Endoscopy.Results: Out of fifty three patients, nineteen (35.8%) cases had normal endoscopy. The most common finding was Antral Gastritis in fourteen (26.4%), followed by Candida esophagitis in twelve (22.6%), esophagitis in three (5.7%), candida esophagitis with antral gastritis in two (3.8%), duodenitis, varices and mass (ulcerated growth) in II part of Duodenum seen in one (1.9%) each.Conclusions: The evaluation of specific gastrointestinal complaints must be based on an assessment of degree of immunosuppression. With the progression of immunodeficiency, EGD becomes a useful diagnostic modality for the early diagnosis of these opportunistic infections and other inflammatory conditions.

scholarly journals A clinico-endoscopic study of upper GI disorders in rural population

2018 ◽  
Vol 5 (3) ◽  
pp. 1111
Author(s):  
Ramesh Ainapure ◽  
Vishal Tanga
Keyword(s):  
Gastrointestinal Tract ◽  
Gastrointestinal Symptoms ◽  
Upper Gastrointestinal Tract ◽  
Common Finding ◽  
Gastrointestinal Disorders ◽  
Oesophageal Varices ◽  
Early Management ◽  
Upper Gi ◽  
Gi Symptoms ◽  
Upper Gastrointestinal

Background: Upper gastrointestinal disorders are commonly seen in routine clinical practice. The definitive diagnosis of upper gastrointestinal disorders rest on endoscopic evaluation and biopsy if required for planning proper treatment. The objectives of the study were to determine the spectrum of disease in upper gastrointestinal tract and to establish endoscopy as an effective tool in the proper diagnosis of various upper gastrointestinal tract disorders.Methods: A prospective study was conducted among patients who presented with upper gastrointestinal symptoms at Gadag Institute Medical College, from August 2016 to August 2017, Gadag. After history taking and physical examination, patients were subjected to fibre-optic upper GI scopy.Results: The result of present study showed male predominance associated with the upper GI disorders. Gastritis (45.65%) was the most common finding followed by normal exam (17.39%), GERD (6.83%), oesophageal cancer (2.17), Oesophagitis (4.34), gastric ulcer (9.31%), and gastric cancer (3.10%), duodenitis (5.90%) and oesophageal varices at 5.27% Gastritis is the most common upper GI disorder seen the patient population.Conclusions: Upper GI endoscopy is an effective and appropriate approach for initial investigation to assess patients with GI symptoms. Thus, it helps early management gastric disorders.

scholarly journals Clinical and endoscopic spectrum of upper gastrointestinal manifestations in HIV patients

1970 ◽  
Vol 8 (1) ◽  
pp. 25-28 ◽  
Author(s):  
VN Ravikumar ◽  
K Rudresh ◽  
U Jalihal ◽  
R Satish ◽  
R Manjunath
Keyword(s):  
Weight Loss ◽  
Epigastric Pain ◽  
Cd4 Count ◽  
Common Finding ◽  
Upper Gi ◽  
Gi Symptoms ◽  
Mucosal Involvement ◽  
The Mean ◽  
Upper Gastrointestinal ◽  
Oesophageal Candidiasis

Background: Human Immunodeficiency Virus (HIV) infected patient frequently report upper gastrointestinal (GI) symptoms; however their prevalence and diagnostic approach is not well known. Objective: The objective of this study was to study clinical, endoscopic and histopathological changes in HIV infected patients with upper GI symptoms and their correlation with CD4 count. Materials and methods: We evaluated 50 HIV infected patients who presented to M.S. Ramaiah hospital with upper GI symptoms. All patients answered questionnaire assessing upper GI symptoms and underwent upper GI endoscopy. Mucosal biopsy was taken wherever mucosal abnormality seen. Results: In our study, the mean age of patients was 40.98 yrs, of which 80% were males. Vomiting (36%), epigastric pain (36 %), weight loss (34 %) and anorexia (34%) were the predominant symptoms. Esophagogastroduodenoscopy (EGD) findings revealed- Oesophageal candidiasis in 28.0%, esophagitis in 22.0%, gastritis in 20.0 %, duodenitis in 14 %, normal upper GI mucosa in 18 % patients. Oesophageal candidiasis was the most common finding on histopathological examination and the mean CD4 count was 157.92 cells/μl. Conclusion: Vomiting, epigastric pain, weight loss and anorexia were most frequent symptoms. Oral candidiasis was the most common oral lesion. Oesophageal candidiasis, oesophagitis and oesophageal ulcers were the common findings on EGD. Patient with CD4 count less than 200cells/μl had more frequent upper GI mucosal involvement than in patients with CD4 count more than 200. Majority of the patients with GI symptoms had upper GI mucosal changes and opportunistic infections. Thus endoscopic and histopathological evaluation is advisable for the early diagnosis and treatment of upper GI complications in patients with HIV infection. Key words: AIDS; Oesophageal candidiasis; Esophagogastroduodenoscopy; HIV; Upper gastrointestinal symptoms. DOI: 10.3126/kumj.v8i1.3217 Kathmandu University Medical Journal (2010), Vol. 8, No. 1, Issue 29, 25-28

scholarly journals Upper Gastrointestinal Symptoms in General Population of a District in Bangladesh

2014 ◽  
Vol 4 (2) ◽  
pp. 79-88
Author(s):  
Irin Perveen ◽  
Mufti Munsurar Rahman ◽  
Madhusudan Saha
Keyword(s):  
General Population ◽  
Gastrointestinal Symptoms ◽  
Duration Of Symptoms ◽  
Upper Gi ◽  
Number Of Patients ◽  
Gi Symptoms ◽  
Number Frequency ◽  
Symptom Prevalence ◽  
Upper Abdominal ◽  
Upper Gastrointestinal

Background: Upper gastrointestinal (GI) symptoms are common complaints affecting 25--40% of the general population and are common causes of health care utilisation and substantially affect the quality of life. In day-to-day practice our clinicians have to face good number of patients with various upper GI symptoms. But we have limited data on the prevalence of different upper GI symptoms in our community. Objective: The present study aimed to find out the prevalence of different upper GI symptoms in the general population of a district in Bangladesh. Materials and Methods: This population-based observational study was conducted in a selected district of Bangladesh. Three thousand subjects selected by cluster sampling method were interviewed by a valid bowel disease questionnaire. Student’s t test and chi-square tests were used for comparison of different variables with significance level set at 0.05. Results: Among the study population 1523 were men and 1477 were women with a mean age of 33.91 ± 16.43 years. A total of 2273 (75.8%) persons had at least one upper GI symptom, 2072 (69.1%) had 2 or more symptoms and 1705 (56.8%) had 3 or more symptoms in the prior 3 months. Nine hundred sixty three subjects (32.1%) had upper abdominal pain, 1265 (42.16%) had bloating, 1354 (45.13%) had heart-burn, 1166 (38.87%) had chest pain, 1347 (44.9%) had early satiation and 258 (8.6%) had vomiting. Around 249 (8.3%, male 123, female 126, P=0.691) was diagnosed as functional dyspepsia, 187 (6.2%, male 82, female 105, P=0.059) as gastroesophageal reflux disease (GERD) and 55 (1.83%, male 27, female 28, P=0.892) as upper abdominal bloating. Only one woman fulfilled the criteria for functional gallbladder or sphincter of Oddi dysfunction. Approximately 40.56% dyspeptic patients had overlapping GERD symptoms. Symptom prevalence was found to decrease with increased number, frequency and duration of symptoms. Conclusion: Upper GI symptoms are prevalent in our community. Multiple upper GI symptoms do exist simultaneously. Symptom prevalence varies with number, frequency and duration of symptoms. DOI: http://dx.doi.org/10.3329/jemc.v4i2.19458 J Enam Med Col 2014; 4(2): 79--88

scholarly journals Investigation of oral, gastric, and duodenal microbiota in patients with upper gastrointestinal symptoms

2020 ◽  
Vol 69 (4) ◽  
pp. 870-877
Author(s):  
Jorge Cervantes ◽  
Majd Michael ◽  
Bo-Young Hong ◽  
Aden Springer ◽  
Hua Guo ◽  
...  
Keyword(s):  
Gastrointestinal Symptoms ◽  
Microbiota Composition ◽  
Gi Tract ◽  
Upper Gi ◽  
Functional Gi Disorders ◽  
Gi Symptoms ◽  
Dyspeptic Symptoms ◽  
Upper Gastrointestinal Symptoms ◽  
Upper Gastrointestinal ◽  
Gastric Microbiota

Disease-associated alterations of the intestinal microbiota composition, known as dysbiosis, have been well described in several functional gastrointestinal (GI) disorders. Several studies have described alterations in the gastric microbiota in functional dyspepsia, but very few have looked at the duodenum.Here, we explored the upper GI tract microbiota of inpatients with upper GI dyspeptic symptoms, and compared them to achalasia controls, as there is no indication for an esophagogastroduodenoscopy in healthy individuals.We found differences in the microbiota composition at the three sites evaluated (ie, saliva, stomach and duodenum). Changes observed in patients with dyspepsia included an increase in Veillonella in saliva, an oral shift in the composition of the gastric microbiota, and to some degree in the duodenum as well, where an important abundance of anaerobes was observed. Metabolic function prediction identified greater anaerobic metabolism in the stomach microbial community of patients with dyspepsia. Proton pump inhibitor use was not associated with any particular genus. Co-abundance analysis revealed Rothia as the main hub in the duodenum, a genus that significantly correlated with the relative abundance of Clostridium, Haemophilus, and Actinobacillus.We conclude that patients with upper GI symptoms consistent with dyspepsia have alterations in the microbiota of saliva, the stomach, and duodenum, which could contribute to symptoms of functional GI disorders.

scholarly journals Analysis of Oesophagogastroduodenoscopy Findings in Patients of Dyspepsia - A Retrospective Study in Coastal Region of Karnataka

2021 ◽  
Vol 8 (21) ◽  
pp. 1679-1684
Author(s):  
Anand Hanumaiah ◽  
Savita K. Sridhar
Keyword(s):  
Retrospective Study ◽  
Gastrointestinal Symptoms ◽  
Coastal Region ◽  
Standard Test ◽  
Common Finding ◽  
Gi Endoscopy ◽  
Ulcer Disease ◽  
Upper Gi ◽  
Upper Gi Endoscopy ◽  
Upper Gastrointestinal

BACKGROUND Dyspepsia is a term used to describe a number of symptoms thought to originate from the upper gastrointestinal tract. It may be caused by a variety of conditions such as peptic ulcer disease, gastro-oesophageal reflux, or even malignancy. Sometimes, dyspepsia is deemed to be functional. Endoscopy helps in differentiating these upper gastro-intestinal (GI) conditions. The objectives of this study were to determine the gastrointestinal findings in patients presenting with dyspepsia in our centre and compare them with those of other studies. METHODS This is a retrospective study of 100 consecutive patients who had undergone upper GI endoscopy for symptoms of dyspepsia from endoscopy data base at Karwar Institute of Medical Sciences, Department of Surgery, from January 2018 to March 2020. RESULTS Out of the total 100 patients who underwent upper GI endoscopy in our institution, 60 were males and 40 were females; youngest was aged 18 years and the oldest was 80 years old. 87 patients had abnormal findings and among these, 29 patients had finding in oesophagus, 54 in the stomach and 04 in the duodenum. A total of 13 patients were reported to be normal. CONCLUSIONS Dyspepsia is much common in males than females. Gastritis is the most common finding on endoscopy followed by oesophagitis and duodenitis other than reflux disorders. Along with proper history and physical examination, endoscopy helps in identifying serious pathologies like malignancy at earlier stage thus reducing morbidity and mortality. Endoscopy is the ‘gold standard test’ for patients with upper gastrointestinal symptoms. KEYWORDS Dyspepsia, Upper GI Endoscopy, Gastritis

scholarly journals Study of upper gastrointestinal endoscopy in patients with gastrointestinal symptoms

2019 ◽  
Vol 6 (10) ◽  
pp. 3595
Author(s):  
Shashidhara Puttaraju ◽  
Sudarshana Sreramaseshadri R. M.
Keyword(s):  
Gastrointestinal Endoscopy ◽  
Gastrointestinal Symptoms ◽  
Significant Risk ◽  
Upper Gastrointestinal Endoscopy ◽  
Therapeutic Tool ◽  
Gi Endoscopy ◽  
Upper Gi ◽  
Gi Symptoms ◽  
Upper Gi Endoscopy ◽  
Upper Gastrointestinal

Background: Upper gastrointestinal (GI) symptoms are the commonest complaints among the general population and the diseases associated with them carries a significant risk of morbidity and mortality. Hence early diagnosis and appropriate management of the condition can prevent life threatening complications. Upper GI endoscopy is an effective diagnostic as well as therapeutic tool for the patients presenting with upper GI symptoms. The objective of the study is to show the effectiveness of upper gastrointestinal endoscopy as an initial diagnostic, screening and therapeutic tool in patients with upper GI symptoms.Methods: Present study comprises of 100 patients presenting with upper gastrointestinal symptoms at JSS Hospital, Chamarajanagar (both out-patients and referred patients) during the period of October 2018 to June 2019, who underwent upper GI endoscopy.Results: Out of 100 patients, 60 were males and 40 were females. In the study majority of the patients were found to have gastritis, esophagitis and acid peptic disease. Other patients had malignant changes, reflux disease, hiatus hernia, perforation, foreign body, obstruction and esophageal varices.Conclusions: Upper GI endoscopy is a simple, safe, more reliable and valuable tool with easy learning curve. It will remain as the initial investigation of choice for the patients with upper GI symptoms. It plays a significant role as a screening, diagnostic as well as therapeutic tool.

scholarly journals Upper Gastrointestinal Symptoms Predictive of Candida Esophagitis and Erosive Esophagitis in HIV and Non-HIV Patients

Medicine ◽  
2015 ◽  
Vol 94 (47) ◽  
pp. e2138 ◽  
Author(s):  
Yuta Takahashi ◽  
Naoyoshi Nagata ◽  
Takuro Shimbo ◽  
Takeshi Nishijima ◽  
Koji Watanabe ◽  
...  
Keyword(s):  
Gastrointestinal Symptoms ◽  
Erosive Esophagitis ◽  
Hiv Patients ◽  
Candida Esophagitis ◽  
Upper Gastrointestinal Symptoms ◽  
Upper Gastrointestinal

scholarly journals The management of upper gastrointestinal symptoms: A study on community pharmacies in Italy

Pharmacia ◽  
2021 ◽  
Vol 68 (2) ◽  
pp. 401-409
Author(s):  
Enrico Keber ◽  
Paolo Rocco ◽  
Umberto M. Musazzi ◽  
Antonio M. Morselli-Labate ◽  
Nicolina P. Floris ◽  
...  
Keyword(s):  
Gastrointestinal Symptoms ◽  
Cross Sectional Study ◽  
Community Pharmacies ◽  
Medication History ◽  
Self Medication ◽  
Cross Sectional ◽  
Therapeutic Class ◽  
Gi Symptoms ◽  
History Of ◽  
Upper Gastrointestinal

Upper gastrointestinal (GI) symptoms are usual complaints among patients presenting to Italian community pharmacies. However, information on treatment history of those patients is often lacking. This descriptive, cross-sectional study aims at exploring the medication history of individuals with upper GI tract symptoms visiting one of the 20 enrolled community pharmacies, over a period of 7 months, based on the administration of a questionnaire. Of 1,020 interviewees, 62.1% had asked for a medical consultation. The most frequent symptom was epigastric burning (31.8%), followed by acid regurgitation (14.6%) and post-prandial fullness (12.0%). Of the 1,609 therapies, proton pump inhibitors constituted the most represented therapeutic class (35.6%) followed by antacids (17.5%) and alginate-based products (17.2%). In treating symptoms, 38.1% of the patients do not seek medical advice, while 42.0% rely on non-prescription therapies. As findings suggest, support to patients with GI disorders in community pharmacies can be enhanced for a safer self-medication.

scholarly journals Pattern of upper gastrointestinal diseases: an audit of 1000 cases based on endoscopic findings from a tertiary care hospital in Mysore

2018 ◽  
Vol 5 (7) ◽  
pp. 2412
Author(s):  
Shashikumar H. B. ◽  
Madhu B. S. ◽  
Motati Harshini
Keyword(s):  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Gastrointestinal Symptoms ◽  
Gastrointestinal Diseases ◽  
Cross Sectional Study ◽  
Common Finding ◽  
Care Hospital ◽  
Cross Sectional ◽  
Endoscopic Findings ◽  
Upper Gastrointestinal

Background: Fibreoptic endoscopy is a highly efficient diagnostic tool, which is now increasingly being used in the diagnosis of upper gastrointestinal diseases. This study has been carried out to evaluate the distribution of various upper gastrointestinal diseases based on endoscopic findings in a tertiary care hospital in Mysore.Methods: A cross-sectional study was conducted based on data from endoscopic register of 1000 subjects who underwent endoscopy for various upper gastrointestinal symptoms from 1st January 2017 to 31st December 2017(one year).Results: Mean age of the study population was 50.23 years (SD-15.46). Minimum age was 12 years and maximum was 88 years. About 44.7% of the study subjects belonged to 40-60 age group.61.6% of the study subjects were males. Most common indication was pain abdomen (32.1%) followed by dysphagia (22.2%). Of the 1000 study subjects 18.6% had normal findings. Most common finding was Gastritis / Duodenitis /Gastric erosions (28%). Malignant lesions were noted among 11.1%, of which esophagus and stomach are 5.4% and 4.9% respectively.Conclusions: Endoscopic diagnosis is useful for early detection of UGI diseases and helpful for their management.

scholarly journals Evaluation of persistent upper abdominal pain by upper gastrointestinal endoscopy

2020 ◽  
Vol 7 (3) ◽  
pp. 791
Author(s):  
Keyur Suryakant Patel ◽  
Prabhat B. Nichkaode ◽  
Sunil V. Panchabhai ◽  
Manichandra Reddy ◽  
Balaji Prathep Santhan ◽  
...  
Keyword(s):  
Abdominal Pain ◽  
Common Finding ◽  
Rapid Urease Test ◽  
Gi Endoscopy ◽  
Upper Gi ◽  
Duodenal Lesions ◽  
Urease Test ◽  
Upper Gi Endoscopy ◽  
Upper Abdominal ◽  
Upper Gastrointestinal

Background: The upper gastrointestinal tract is affected by a spectrum of conditions which span from infectious, idiopathic, inflammatory diseases, polyps, motility disorders and malignancy. Upper gastrointestinal scopy is believed to be the most effective screening modality as it not only allows direct visualization of oesophagus, gastric and duodenal mucosa but to perform biopsies in suspected malignancies. Aim: To evaluate persistent upper abdominal pain by upper gastrointestinal scopy.Methods: A total of 100 patients presented with complains of persistent upper abdominal pain were subjected to upper gastrointestinal scopy. Biopsies in indicated cases were taken from abnormal areas and sent for histopathology.Results: Most common finding in patients according to upper gastrointestinal scopy was gastritis (27%), followed by duodentitis (9%), and gastroduodenitis (7%). Rapid urease test in cases of gastritis and duodenitis to determine H. pylori infection were positive in 53.8% cases.Conclusions: Because of its precision and relatively safe technique upper GI endoscopy can be considered in patients above age of 50 years presenting to surgical OPD with complaints of persistent pain in upper abdomen. Investigating helicobacter pylori should be considered in all patients found to have gastric or duodenal lesions on upper GI endoscopy as its association with these lesions ranges from 50 to 80%.

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