scholarly journals Demographic and clinic-angiographic profile of coronary artery disease in young adults: a retrospective observational study

2018 ◽  
Vol 6 (7) ◽  
pp. 2264 ◽  
Author(s):  
Lalatendu Swain ◽  
Prabhat Nalini Routray
Keyword(s):  
Young Adults ◽  
Heart Disease ◽  
Coronary Artery ◽  
Coronary Angiography ◽  
Observational Study ◽  
Young Patients ◽  
Retrospective Observational Study ◽  
Age Group ◽  
Artery Disease ◽  
One Year

Background: Cardiovascular diseases (CVD) and its complications are on an increased trend in the younger age group. In this study we aimed to identify the different risk factor profile and coronary angiographic characteristics of young adults presenting with coronary artery disease.Methods: We conducted this retrospective observational study at SCB MC and H and Ashwini Hospital, Cuttack, Odisha, India over a period of one year from June 2016 to June 2017 on 170 patients who undergone coronary angiogram. Inclusion criteria being patients admitted for STEMI, NSTEMI, or UA, age <40 years and those who underwent coronary angiography. All patients who underwent coronary angiography for surgical fitness e.g., patients of rheumatic heart disease and congenital heart disease were excluded from the study.Results: Among the 150 cases included in the study, 85.3%were males and 14.7% were females. Maximum number of cases i.e. 71.3% were in the age group 36-40 yr, while 23.3% were between 31-35 and 5.4% were between 25-30 age group. Among 150 cases with critical CAD, SVD was most prevalent seen in 68.7% cases, followed by DVD in 22.6% and TVD in 8.7% cases.Conclusions: Incidence of critical CAD in young adults is quite high. Young patients with CAD are mainly males, and SVD is more common. Comparative analysis of young patients with STEMI and NTEMI/ UA revealed that SVD was predominantly involved in STEMI group, whereas TVD was predominant in NSTEMI/UA group.

scholarly journals Hyperuricemia and Smoking Correlation in Egyptian Young Adults with Coronary Artery Disease: Observational Study

2021 ◽  
pp. 45-50
Author(s):  
Ali Youssef El-Sayed Youssef ◽  
Seham Fahmy Badr ◽  
Mohamed Ahmed Abd El-Aal ◽  
Ayman Ahmed El-Sheikh
Keyword(s):  
Risk Factors ◽  
Coronary Artery Disease ◽  
Young Adults ◽  
Coronary Artery ◽  
Coronary Angiography ◽  
Observational Study ◽  
Gensini Score ◽  
Score System ◽  
Clear Association ◽  
Artery Disease

Background: Young adults, especially those under 35, are often overlooked; however, previous studies have shown that coronary artery disease (CAD) incidence increases rapidly. Previous studies proved many risk factors for CAD, such as hyperlipidemia, hypertension, diabetes, and smoking. The present study ultimately aimed to figure out the correlation between Hyperuricemia (HUA) and smoking in CAD Patients under the age of 35. Methods: This observational study included 100 young adults (18–35 years of age) suspected of CAD. We used the Gensini Score system to ascertain coronary angiography outcome and CAD; based on the number of affected vessels, localization of the segment, and the stenosis grade. The Gensini score being > 0 indicated the presence of CAD. Results: In young adults under 35, there was a significant correlation between HUA and CAD. The interaction between HUA and smoking had a contrast for CAD that statistically shown the existence of CAD increased in patients who have hyperuricemia and non-smokers compared to smokers. Conclusions: By monitoring various parameters in young adults ≤ 35 years old. This study strengthens the correlation between:1) hyperuricemia and the occurrence of CAD, 2) Smoking and the CAD. Furthermore, there is a clear association between HUA and the occurrence of CAD in non-smokers.

Abstract 342: Impact Of System And Physician Factors On The Diagnostic Yield Of Coronary Angiography In Stable Ischemic Heart Disease: A Population Based Study

2014 ◽  
Vol 7 (suppl_1) ◽  
Author(s):  
Harindra C Wijeysundera ◽  
Feng Qiu ◽  
Maria C Bennell ◽  
Madhu K Natarajan ◽  
Warren J Cantor ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Heart Disease ◽  
Coronary Artery ◽  
Coronary Angiography ◽  
Ischemic Heart Disease ◽  
Diagnostic Yield ◽  
Obstructive Coronary Artery Disease ◽  
Ischemic Heart ◽  
Patient Factors ◽  
Artery Disease

Background: Wide variation exists in the diagnostic yield of coronary angiography in stable ischemic heart disease (IHD). Previous work has primarily focused on patient factors for this variation. We sought to understand if system and physician factors, specifically hospital and physician type, as well as physician self-referral, have incremental impacts on the yield of coronary angiography, above and beyond that of patient factors alone. Methods: All patients who underwent a diagnostic coronary angiogram for possible stable IHD, at the 18 cardiac centers in Ontario, Canada were identified from October 1st, 2008 to September 30th, 2011. Obstructive coronary artery disease was defined as stenosis greater than 70% in the main coronary arteries or greater than 50% in the left main artery. Physicians were classified as either invasive or interventional. Hospitals were categorized into cath only, stand-alone PCI and full service centers. Multi-variable hierarchical logistic models were developed to identify system and physician level predictors of obstructive coronary artery disease, having adjusted for patient factors. Results: Our cohort consisted of 60,986 patients who underwent a diagnostic angiogram for possible stable IHD, of which 33,483 had obstructive coronary artery disease (54.9%), ranging from 41.0% to 70.2% across centers. Self-referral rates varied from 4.8% to 74.6%. Fewer self-referral patients (52.5%) had obstructive coronary artery disease compared to non-self-referral patients (56.5%), with an odds ratio (OR) of 0.89 (95% CI 0.85-0.93;p <0.001), after accounting for patient factors. Angiograms performed by interventional physicians had a higher likelihood of showing obstructive coronary artery disease (60.1% vs. 50.8%; OR 1.22; 95% CI 1.17-1.28; p<0.001). Fewer angiograms at cath only centers showed obstructive disease (45.0%) compared to full service centers (58.1%); this was of borderline significance (OR 0.59; 95% CI 0.34-1.00; p=0.05). Conclusion: Physician and system factors are important predictors of the diagnostic yield of coronary angiography in stable IHD, even after accounting for patient characteristics. Further study into the drivers of how these physician and system factors impact diagnostic yield is an important focus for quality improvement.

scholarly journals A Rare Cause of Supraventricular Ectopic Beats and Angina in a Young Patient

2018 ◽  
Vol 4 (2) ◽  
pp. 106-109
Author(s):  
Monica Jurcău ◽  
Mariana Floria ◽  
Bogdan Mazilu ◽  
Anca Ouatu ◽  
Daniela Maria Tanase
Keyword(s):  
Coronary Artery ◽  
Stress Test ◽  
Young Patients ◽  
Physical Exertion ◽  
Diagnostic Techniques ◽  
History Of ◽  
Ectopic Beats ◽  
Artery Disease ◽  
One Year ◽  
The Right

Abstract Introduction: We present the case of a young man with multiple atherosclerotic risk factors and a rare cause of angina and supraventricular ectopic beats. Case presentation: A 35-year-old man with one-year history of stable angina pectoris and supraventricular ectopic beats, without any medication, presented to the emergency room complaining of anterior chest pain that occurs at moderate physical exertion. The rest electrocardiogram, transthoracic echocardiography, and chest X-ray were normal; the exertion stress test was also normal, except for supraventricular ectopic beats (trigeminal rhythm). Due to the intermediate pre-test probability of coronary artery disease, he was evaluated using coronary computed tomography angiography. An anomalous origin of the right coronary artery from the left coronary sinus, with an inter-arterial course and without any atheroma plaques, was observed. During hospitalization the evolution was stable, without complications. The patient was further referred to a cardiac surgery clinic to evaluate the possibility of surgical treatment of this anomaly. Conclusions: Coronary artery anomalies are very rare; however, they present multiple implications in current practice. The most severe complication of this condition is represented by sudden death in young patients due to malignant ventricular arrhythmias. Imaging diagnostic techniques allow for a rapid, noninvasive diagnosis of this rare cause of angina.

scholarly journals Coronary lesions suggestive of kawasaki disease in young patients presenting with acute myocardial infarction

2021 ◽  
Vol 42 (Supplement_1) ◽  
Author(s):  
F Solis-Jimenez ◽  
H Gonzalez Pacheco ◽  
J Calderon Colmenero ◽  
J Cervantes Salazar ◽  
D Manzur Sandoval ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Young Adults ◽  
Coronary Artery ◽  
Kawasaki Disease ◽  
Coronary Angiography ◽  
Clinical Characteristics ◽  
Young Patients ◽  
Coronary Aneurysms ◽  
Coronary Lesions

Abstract Background Approximately 25% of patients with untreated Kawasaki disease (KD) in childhood develop coronary aneurysms, which represent a higher likelihood for the occurrence of acute myocardial infarction (AMI) in young adults. Although the clinical characteristics of young adults with KD and suspected ischemia have been studied, the available data about suggestive lesions of KD in AMI is scarce. Purpose To describe the prevalence, clinical characteristics and in-hospital mortality of young adults with AMI and coronary artery lesions suggestive of KD. Methods We conducted a retrospective study of consecutive ≤40-year old patients hospitalized with AMI and coronary angiography in a coronary care unit of a Mexican teaching hospital between 2006–2020. Patients were classified according to the presence or absence of suggestive lesions of KD sequelae such as proximal aneurysms, larger size and normal distal segments Results There were included 488 patients of 40 years of age and younger, diagnosed with AMI, in whom a coronary angiography was performed. Among them, 44 patients (9%) showed coronary aneurysm or ectasia, within this group, 16 patients (36.3%) had angiographic lesions compatible with KD. The patients were classified according to the type of coronary lesions: Angiographic lesions compatible with KD, 3.3% (n=16); Diffuse coronary artery ectasia (CAE), 5.7% (n=28); and Obstructive coronary disease (OCD), 91% (n=444). The prevalence of smoking, dyslipidemia, and hypertension were similar between the groups, whereas a history of diabetes was absent in KD patients (0%, 10.7%, and 22.1% for KD, CAE and OCD, respectively; P=0.04). At admission, ST-elevation myocardial infarction was more frequent in patients with KD (81.3%, 75%, and 67.1% for KD, CAE and OCD, respectively; P=0.35). More than half of patients with KD had coronary aneurysms in two or more vessels. The right coronary artery was the most commonly affected artery followed by the left anterior descending artery and left circumflex coronary artery (87.5%, 56.3% and 56.3%, respectively). The presence of intracoronary thrombus identified at the time of angiography was more frequent in patients with KD (62.5%, 60.7% and 44.1% for KD, CAE and OCD, respectively; P=0.09). Overall, unadjusted in-hospital mortality was 3.9% and there were no deaths in the KD group (0%, 0% and 4.3% for KD, CAE, and OCD, respectively; P=0.37). Conclusion In young patients with AMI, the sequelae of KD should be considered as a possible etiology, based on their angiographic characteristics. To bear in mind the nature of the pathogenesis is crucial to assess medical and interventional management strategies, which are not well defined yet, in order to evaluate cardiovascular risk and optimize a patient-tailored treatment, which could differ from the treatment of atherosclerotic coronary artery disease FUNDunding Acknowledgement Type of funding sources: None. Figure 1 Figure 2

scholarly journals Polygamy and Risk of Coronary Artery Disease in Men Undergoing Angiography: An Observational Study

2017 ◽  
Vol 2017 ◽  
pp. 1-6 ◽  
Author(s):  
Amin Daoulah ◽  
Amir Lotfi ◽  
Mushabab Al-Murayeh ◽  
Salem Al-kaabi ◽  
Salem M. Al-Faifi ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Coronary Angiography ◽  
Observational Study ◽  
Marital Status ◽  
Artery Bypass ◽  
Continuous Variable ◽  
Multicenter Observational Study ◽  
Married Men ◽  
Artery Disease

Epidemiologic evidence suggests a link between psychosocial risk factors such as marital status and coronary artery disease (CAD). Polygamy (multiple concurrent wives) is a distinct marital status practiced in many countries in Asia and the Middle East, but its association with CAD is not well defined. We conducted a multicenter, observational study of consecutive patients undergoing coronary angiography during the period from April 1, 2013, to March 30, 2014. Of 1,068 enrolled patients, 687 were married men. Polygamy was reported in 32% of married men (1 wife: 68%, 2 wives: 19%, 3 wives: 10%, and 4 wives: 3%). When stratified by number of wives, significant baseline differences were observed in age, type of community (rural versus urban), prior coronary artery bypass grafting (CABG), and household income. After adjusting for baseline differences, there was a significant association between polygamy and CAD (adjusted OR 4.6 [95% CI 2.5, 8.3]), multivessel disease (MVD) (adjusted OR 2.6 [95% CI 1.8, 3.7]), and left main disease (LMD) (adjusted OR 3.5 [95% CI 2.1, 5.9]). Findings were consistent when the number of wives was analyzed as a continuous variable. In conclusion, among married men undergoing coronary angiography for clinical indications, polygamy is associated with the presence of significant CAD, MVD, and LMD.

scholarly journals CORONARY ARTERY ECTASIA;

2017 ◽  
Vol 24 (04) ◽  
pp. 545-553
Author(s):  
Liaqat Ali ◽  
Naeem Asghar ◽  
Muhammad Yasir
Keyword(s):  
Coronary Artery ◽  
Coronary Angiography ◽  
Descriptive Study ◽  
Type I ◽  
Age Group ◽  
Coronary Artery Ectasia ◽  
Study Materials ◽  
Coronary Ectasia ◽  
Artery Disease ◽  
Diagnostic Coronary Angiography

Background: Coronary artery ectasia (CAE) is well-recognized but relativelyuncommon finding during diagnostic coronary angiography. Coronary artery ectasia is definedas a segment of coronary artery that is 1.5 times more dilated in diameter than the nearbysegments. Its clinical presentations are unstable angina, coronary vasospasm, and acutemyocardial infarction. Objectives: To determine the clinical characteristics, presentation andtreatment in patients with documented coronary artery ectasia in a single Cardiac Centreat Faisalabad City Pakistan. Study Design: Retrospective descriptive study. Materials andMethods: This was a single center retrospective, descriptive study. Patients of either genderwith age 21-70 years who had coronary angiography at Faisalabad Institute of CardiologyFaisalabad were included in the study. Coronary angiograms performed from April 2013 toDecember 2016 were reviewed. Patients fulfilling inclusion and exclusion criteria were enrolled.Clinical and angiographic profiles of the patients having coronary ectasia were retrievedfrom hospital record. Clinical profile included: age, gender and cardiovascular risk factors.Angiographic profile; prevalence of coronary ectasia, type of ectasia, associated obstructivedisease and coronary vessel involved were noted. Results: Total 22235 patients under wentcoronary angiography from April 2013 to December 2016 at Faisalabad Institute of CardiologyFaisalabad. Out of 22235, 16913(76%) were male and 5322(24%) were female. Coronary arteryectasia (CAE) was observed in 1044(4.7%). Out of 1044, 931(89%) were male and 113(10.9%)were female patients. Mean age of study population was 49.5 ± 11.8 years. 368(31.97%) patientswith CAE were in age group of 51-60 years followed by age group 41-50 years. 672 (64.36%)were hypertensive, 433 (41.7%) were diabetics, smoker were 574(54.98%). 442(42.33%)patients presented with ST elevation MI. 750 (71.84%) patient had mild Ectasia, 155 (34.87%)were suffering from severe coronary Ectasia. 364 (34.87%) patients had associated obstructivecoronary artery disease. LAD was most commonly involved vessel in 392 (37.50%) followed byright coronary artery in 323 (30.94%). Type I ectasia was documented in 34.92%. Conclusions:In our study prevalence of CAE was 4.7%. CAE was more common in male, hypertensive,smokers and patients with Hyperlipedemia. Most common pattern of CAE was Type I andisolated ectasia without coronary artery obstruction. Left anterior descending artery was themost commonly involved vessel in ectasia followed by RCA.

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