scholarly journals Role of triple assessment modalities in diagnosis of palpable breast lump

2018 ◽  
Vol 6 (10) ◽  
pp. 3435
Author(s):  
Ashwinkumar S. Gadhvi ◽  
Udit I. Gadhvi ◽  
Dhaval A. Bhimani ◽  
Darshil K. Rajgor
Keyword(s):  
Benign Lesion ◽  
Malignant Lesion ◽  
Breast Disease ◽  
Breast Lump ◽  
Size Number ◽  
Life Saving ◽  
Triple Assessment ◽  
Palpable Breast ◽  
Sensitivity Specificity

Background: One fourth of women suffer from breast disease in their lifetime. Carcinoma of breast is the second most common cancer in the world. Timely and accurate diagnosis of breast lump with early intervention can be life saving. There are various modalities for the diagnosis of breast lump such as USG, FNAC and Mammography, MRI etc. but none of them is perfect. There are numerous reports suggesting that if the results of clinical assessment, mammography and FNAC are all combined, the diagnostic accuracy is nearly 100%. Furthermore, these techniques also provide information about tumor size, number, extent and grade preoperatively.Methods: Study was randomized, prospective, observational and longitudinal including 100 patients, selected according to inclusion criteria.Results: The sensitivity, specificity and accuracy of triple test in present study were 98.68%, 87.5%, and 96% respectively. Out of 100, 76 patients were confirmed as having benign lesion and 24 patients having malignant lesion by histopathology examination.Conclusions: Results of triple assessment are same as the results by histopathology examination in majority of cases. It is highly accurate, can be used as a confirmatory diagnostic tool for breast lump, thus there is no need to perform diagnostic open biopsy for breast lump.

scholarly journals Mammographic evaluation of palpable breast masses with pathological correlation: a tertiary care centre study in Nepal

1970 ◽  
Vol 32 (2) ◽  
pp. 21-25 ◽  
Author(s):  
G Gurung ◽  
RK Ghimire ◽  
B Lohani
Keyword(s):  
Breast Cancer ◽  
Benign Lesion ◽  
Tertiary Care ◽  
False Negative ◽  
Malignant Lesion ◽  
Institute Of Medicine ◽  
Breast Lump ◽  
Major Health Problem ◽  
Malignant Lesions ◽  
Palpable Breast

Introduction: Breast cancer is one of the major health problem for all countries. . In Nepal , breast cancer is the second most common cancer in female. Early detecting tools like mammography can able to detect location , size, morphology, and nature of breast lesions that can help to reduced mortality and morbidity from breast cancer significantly. Methods: This prospective study was carried out at the department of Radiology, Surgery and Pathology for a period of one year. A total of 100 patients with clinically palpable breast lump were subjected to mammography and subsequently to FNA or biopsy. The mammograms were reviewed by two senior consultant radiologists and pathology by a senior pathologist. Results: Out of 100 patients, 65% had mammographic features of benign lesion and 35% had features of malignancy. Pathology revealed 64% of lesion to be benign and 36% of lesion to be malignant. There were four false negative (6.2%) and three false positive (8.6%) cases. The sensitivity and specificity of mammography were 88.9% and 95.53% respectively. The mean age of patient with malignant lesion was 46.3 years (SD=11.5) and 34.7 years (SD=10.6) for benign lesions. Among malignant lesion 37.1% had lobulated, 14.3% had oval, 31.4% round and 17.1% had irregular shape with spiculated margin in 60% and indistinct margins in 34.3%. Among benign 7.7% showed lobulated shape, 41.5% oval and 50.8% round shape. Circumscribed margin was found in 93.9% of benign and 5.7% of malignant lesions. Punctuate and polymorphic calcification was found in malignant lesions (25.7% and 5.7%). Secondary changes were found in only in the malignant cases. Halo sign was found only in benign cases and most common in fibroadenoma (38.4%). Conclusions: Mammography is an effective diagnostic tool for benign and malignant characteristic of palpable breast mass. Keywords: Breast lump; mammography; micro calcification DOI: http://dx.doi.org/10.3126/joim.v32i2.4940 Journal of Institute of Medicine, August, 2010; 32: 21-25

scholarly journals THE VALUE OF MODIFIED TRIPLE ASSESSMENT IN THE DIAGNOSIS OF PALPABLE BREAST LUMPS

2019 ◽  
Vol 3 (5) ◽  
Author(s):  
Dr. S. Raviraj ◽  
Dr. V. Vinitharan
Keyword(s):  
Benign Lesion ◽  
Malignant Lesion ◽  
Clinical Problem ◽  
Breast Lesions ◽  
Validity And Reliability ◽  
Early Evaluation ◽  
Triple Assessment ◽  
Palpable Breast ◽  
Breast Lumps ◽  
Common Clinical Problem

Breast Lumps in females are a common clinical problem which requires rapid and early evaluation with an important aim of excluding any breast malignant lesion. We have modified this approach by substituting mammogram with ultrasound for the assessment of breast lesions. Distinction of benign lesion of breast from malignant lesion is of paramount importance for patient care and proper management. An early and accurate diagnosis is important because the treatment can be initiated much earlier for the better prognosis. Nowadays Triple assessment has been used as a main diagnostic method in the evaluation of breast lesions. Therefore it is important to evaluate the validity and reliability of triple assessment in the evaluation of breast lesion.

scholarly journals Study of clinical, imaging and pathological assessment of breast lumps: an observational study

2020 ◽  
Vol 7 (5) ◽  
pp. 1452
Author(s):  
Sumedha Laul ◽  
Divish Saxena ◽  
Nitin Wasnik
Keyword(s):  
Final Diagnosis ◽  
Needle Aspiration ◽  
Age Group ◽  
Breast Lump ◽  
Aspiration Cytology ◽  
Malignant Breast ◽  
Palpable Breast ◽  
Needle Aspiration Cytology ◽  
Breast Lumps

Background: A palpable lump in a woman’s breast could be benign or malignant and it requires prompt evaluation to confirm or exclude cancer. This study aims to establish the correlation between clinical and radiological parameters for provisional diagnosis of breast lumps and the role of histopathology for final diagnosis of these breast lumps.Methods: Total 275 female patients with palpable breast lumps were included in the study, where a detailed history was recorded and clinical examination was done. All patients underwent ultrasonography of the breast along with fine needle aspiration cytology or histopathology, wherever indicated.Results: Benign breast lumps were found more commonly in 18-30 years of age group whereas malignant breast lumps were seen more commonly in the 41-60 years age group and the incidence increased with age. Fixity to skin was present in 5.1% and fixity to chest wall was present in 5.8% respectively, and all of these cases turned out to be malignant.Conclusions: Attributing factors for suspicion of malignant lumps are advanced age, fixity to surrounding structures, presence of ulceration and peau’d orange breast skin appearance. Although for confirmation of malignancy from a suspected breast lump requires either cytology or histopathology of the excised specimen.

scholarly journals A comparative clinicopathological study between ultrasonography, mammography, FNAC and core needle biopsy of breast lump

2020 ◽  
Author(s):  
Arnab Mandal ◽  
Pradipta Jana ◽  
Sabyasachi Bakshi ◽  
Ram Krishna Mandal
Keyword(s):  
Core Needle Biopsy ◽  
Predictive Value ◽  
Needle Biopsy ◽  
Breast Disease ◽  
Ultra Sound ◽  
Benign Lesions ◽  
Breast Lump ◽  
Core Needle ◽  
Carcinoma Breast ◽  
Sensitivity Specificity

Abstract BACKGROUND:Early presentation and prompt diagnosis is the essential key in treatment of different variety of neoplastic as well as non-neoplastic breast disease. In this study usefulness of HRUSG, Mammography, FNAC and Core Needle Biopsy in correlation with histopathological pattern, was assessed.METHODS:After matching the criteria, 212 cases, were taken for this prospective, single center, observational study. RESULTS:Out of 212 cases, 163(76.88 %%) were benign lesions, 49(23.11%) were malignant and 1(0.47%) were of inflammatory pathology. Benign to malignant breast disease ratio was 3.3:1. Out of 49 malignant cases, 45 (91.83%) were ductal cell carcinoma and 4 (8.16%) was apocrine carcinoma. Maximum numbers of cancer patients were found in the 51- 60 year age groups.The sensitivity, specificity, Positive predictive value and Negative Predictive value of mammography in detecting carcinoma breast were 87.76%, 64.71%, 87.76% and 64.71% respectively. The sensitivity, specificity, PPV and NPV of HRUSG in detecting carcinoma breast were 85.71%, 90.18%, 72.41% and 95.45% respectively.Among benign lesions, 47 (28.83) % were diagnosed by mammography and 147(90.18) % were diagnosed by HRUSG. When these modalities were combined, >95% of the lesions was diagnosed accurately.CONCLUSIONS:Ultra sound used liberally as an adjunct to mammography, increase the cancer detection rate. Core needle biopsy is found more accurate but FNAC have limited value in evaluation of benign breast lump. This study also proves that preoperative categorization of breast lesions is utmost important for management of the patient and this will help to avoid unnecessary surgical treatment.

scholarly journals Role of triple test score in the evaluation of palpable breast lump

2015 ◽  
Vol 36 (2) ◽  
pp. 123 ◽  
Author(s):  
SmitaSushil Kachewar ◽  
SuryakantDattatraya Dongre
Keyword(s):  
Test Score ◽  
Breast Lump ◽  
Triple Test ◽  
Palpable Breast

scholarly journals A PILOT STUDY FOR EVALUATION OF ROLE OF B-MODE ULTRASOUND AND STRAIN ELASTOGRAPHY IN DIFFERENTIATING BENIGN AND MALIGNANT BREAST MASSES

2021 ◽  
pp. 153-163
Author(s):  
SARYU GUPTA ◽  
MANPREET KAUR ◽  
AMARJIT KAUR ◽  
KULDEEP BHATIA
Keyword(s):  
Pilot Study ◽  
Diagnostic Accuracy ◽  
Ductal Carcinoma ◽  
Strain Ratio ◽  
Breast Lump ◽  
Breast Masses ◽  
Strain Elastography ◽  
Malignant Breast ◽  
Palpable Breast ◽  
Sensitivity Specificity

Background: Early detection of malignant lesions is critical key stone for the successful management of breast cancer. Conventional B-mode ultrasound although could not replace the histopathology which is still gold standard, plays an important role in the diagnostic pathways by using the Breast Imaging Reporting and Data System (BIRADS) lexicon (standardized by American College of Radiology [ACR]). Although characterization of solid breast masses by sonography has improved greatly since the early 1990s, specificity remains low and a large number of biopsies result in benign diagnosis. Strain elastography and strain ratio (SR) are recent techniques which may help in increasing the specificity of ultrasound. Methods: The present study was a pilot study aimed to establish a correlation between B-mode ultrasound and strain elastography in differentiating benign and malignant breast masses and to compare the results of B- mode ultrasound and Strain Elastography with fine-needle aspiration cytology/ biopsy findings. It was a prospective study conducted in the Department of Radio-diagnosis of Rajindra Hospital, Patiala. A total of 40 patients who presented with the complaint of palpable breast lump were evaluated with B-Mode Ultrasonography (USG) and Strain elastography (using elastography score [ES] and SR). Results: The study group (40 patients with breast lumps) comprised 38 (95%) female patients and 2 (5%) male patients. Among the group 29 were benign and 11 were malignant. Fibroadenoma followed by fibrocystic disease was the most common benign pathologies and invasive ductal carcinoma followed by Ductal Carcinoma in situ was the most common malignant pathologies. Sensitivity, specificity, and diagnostic accuracy of B-Mode USG in diagnosing palpable breast lump are 72.7%, 86.2%, and 82.5%, respectively, while that of strain elastography in diagnosing palpable breast lump are 81.8%, 93.10%, and 90.0%, respectively. Using strain ratio (SR) only the sensitivity, specificity, and diagnostic accuracy was found to be 93.1%, 100%, and 95% better than B-Mode USG and shear elastography alone separately and combined. The mean SR for a benign mass is 2.00±0.97 and for a malignant mass is 5.40±1.55. Conclusion: Ultrasound elastography (using ES) has a higher sensitivity, specificity and diagnostic accuracy in differentiating benign and malignant breast masses then B mode USG (using BIRADS). Using SR alone has shown better sensitivity, specificity, and diagnostic accuracy but its standalone or in combination diagnostic application has to be followed up with further studies.

scholarly journals A comparative clinicopathological study between ultrasonography, mammography, fine needle aspiration cytology and core needle biopsy of breast lump

2020 ◽  
Vol 7 (7) ◽  
pp. 2325
Author(s):  
Arnab Mandal ◽  
Pradipta Jana ◽  
Sabyasachi Bakshi ◽  
Ram Krishna Mandal
Keyword(s):  
Core Needle Biopsy ◽  
Predictive Value ◽  
Needle Biopsy ◽  
Breast Disease ◽  
Needle Aspiration ◽  
Breast Lump ◽  
Aspiration Cytology ◽  
Core Needle ◽  
Needle Aspiration Cytology ◽  
Sensitivity Specificity

Background: Early presentation and prompt diagnosis is the essential key in treatment of different variety of neoplastic as well as non-neoplastic breast disease. In this study usefulness of high-resolution ultrasonography (HRUSG), mammography, fine needle aspiration cytology (FNAC) and core needle biopsy in correlation with histopathological pattern, was assessed.Methods: After matching the criteria, 212 cases, were taken for this prospective, single center, observational study.Results: Out of 212 cases, 163 (76.88%) were benign lesions, 49 (23.11%) were malignant and 1 (0.47%) were of inflammatory pathology. Benign to malignant breast disease ratio was 3.3:1. Out of 49 malignant cases, 45 (91.83%) were ductal cell carcinoma and 4 (8.16%) was apocrine carcinoma. Maximum numbers of cancer patients were found in the 51-60-year age groups. The sensitivity, specificity, positive predictive value and negative predictive value of mammography in detecting carcinoma breast were 87.76%, 64.71%, 87.76% and 64.71% respectively. The sensitivity, specificity, positive predictive value and negative predictive value of HRUSG in detecting carcinoma breast were 85.71%, 90.18%, 72.41% and 95.45% respectively. Among benign lesions, 47 (28.83%) were diagnosed by mammography and 147 (90.18%) were diagnosed by HRUSG. When these modalities were combined, >95% of the lesions was diagnosed accurately.Conclusions: Ultra sound used liberally as an adjunct to mammography, increase the cancer detection rate. Core needle biopsy is found more accurate but FNAC have limited value in evaluation of benign breast lump. This study also proves that preoperative categorization of breast lesions is utmost important for management of the patient and this will help to avoid unnecessary surgical treatment.

scholarly journals The spectrum of palpable breast lesions- A cytopathological study of 1193 cases

2021 ◽  
Vol 7 (3) ◽  
pp. 144-149
Author(s):  
Manasa GC ◽  
◽  
Sneha SP ◽  
Adicherla Govardhan ◽  
◽  
...  
Keyword(s):  
Ductal Carcinoma ◽  
Tertiary Care ◽  
Needle Aspiration ◽  
Female Breast Cancer ◽  
Care Hospital ◽  
Age Group ◽  
Breast Lump ◽  
Palpable Breast ◽  
Needle Aspiration Cytology ◽  
Sensitivity Specificity

Introduction- The vast majority of the lesions that occur in the breast are benign. Much concern isgiven to malignant lesions of the breast because female breast cancer has now surpassed lungcancer as the leading cause of global cancer incidence in 2020. Fine needle aspiration cytology(FNAC) has good sensitivity, specificity and accuracy in the diagnosis of both neoplastic and non-neoplastic breast lump thereby assisting in early diagnosis and further management. The currentstudy was done to study the incidence and the different cytomorphological patterns of palpablebreast lumps by FNAC and consequently compare the results with studies in the literature.Materials and methods- This is a retrospective study conducted from January 2018 to December2020 in a tertiary care hospital. The three-year data is obtained from the records maintained in theFNA clinic. The patients were counselled before the procedure and informed consent was taken.Results- A total of 1193 breast lump cases were analysed in this 3-year study, there were 19 malepatients all of them presented with gynaecomastia and 1177 female patients. The patient’s agegroup ranged from 12 to 86 years. The commonest age group with the lesions 31-40 yearscomprising 326 cases (27.32%) followed 21-30 years age group in the second place with 307 cases(25.7%). Conclusion- In this study the most common benign neoplastic and malignant neoplasticbreast lumps are fibroadenoma and infiltrating ductal carcinoma respectively. Fibrocystic disease ofthe breast is the most common non-neoplastic breast lump.

scholarly journals Different Types of Breast Lump in Relation to Different Age Groups

2014 ◽  
Vol 8 (2) ◽  
pp. 56-58
Author(s):  
ABM Zafar Sadik ◽  
Md Mahmudul Hasan ◽  
Nur-E-Zannat Afroza Haque ◽  
Farid Uddin Ahmed ◽  
Md Zahidul Kabir
Keyword(s):  
Breast Carcinoma ◽  
Age Groups ◽  
Breast Disease ◽  
Needle Aspiration ◽  
Breast Lump ◽  
College Hospital ◽  
Medical College ◽  
Group A ◽  
Palpable Breast ◽  
Needle Aspiration Cytology

This prospective observational study was carried out in the inpatient and outpatient department of surgery at Shaheed Ziaur Rahman Medical College Hospital, Bogra, during the period of 01.07.2008 to 31.12.2008 with a view to find out the incidence of breast carcinoma, fibroadenoma or other pathology in different age group. A total 130 patients with palpable breast lump were included in the study. Age of the patients was between 11 to 70 years. In most of the patients with breast lump Fine Needle Aspiration Cytology and biopsy were done. Sometimes ultrasonography, mammography and other routine investigations were also done. Among the study population 53.85% had benign lesions, Breast carcinoma accounted for 46.15% cases, fibroadenoma for 40.76% and fibroadenosis were in 10% cases. Fibroadenoma was common in second and third decade, while carcinoma of breast was common in third and fourth decade in this study. Here we attempted to find out the age incidence of breast lump and its correlation with clinical features, FNAC findings and histopathological report to improve the accuracy of diagnosis and management of breast disease. DOI: http://dx.doi.org/10.3329/fmcj.v8i2.20369 Faridpur Med. Coll. J. 2013;8(2): 56-58

ROLE OF MAMMOGRAPHY AND CORE BIOPSY IN THE DIAGNOSIS OF BREAST TUMOR

2017 ◽  
pp. 69-72
Author(s):  
Trong Hung Phan ◽  
Cong Thuan Dang ◽  
Thanh Thao Nguyen
Keyword(s):  
Breast Cancer ◽  
Positive Predictive Value ◽  
Predictive Value ◽  
Breast Tumor ◽  
Core Biopsy ◽  
Breast Tumors ◽  
Breast Disease ◽  
University Hospital ◽  
Sensitivity Specificity

Introduction: Breast tumor is a popular disease. Breast cancer is the most common cancer in women. Mammography is the chosen screening test and ultrasound-guided core-needle biopsy provides (US-CNB) the pathologic result for treatment. Objective: To study the role of mammography and core biopsy in diagnosis of breast tumors. Materials and methodology: Prospective and retrospective study of 33 breast tumors examined mammograms at Hue University Hospital and Hue Central Hospital from 7/2014 to 4/2017. Results: Mean age of breast cancer: 52 years old, of benign breast disease: 53 years old. 86% of all cases admitted to hospital due to self-detecting breast tumor. Locations: 0-3h 33.3%, 9-12h 27.2%. Sensitivity, specificity and accuracy of mammography were 76.9%, 28.6% and 66.7% respectively. Sensitivity, specificity, positive predictive value, negative predictive value, accuracy value of US-CNB were 95.2%, 85.6%, 95.2%, 85.6% and 92.9%, respectively. The value of combined with mammograms and US-CNB has improved the specificity and positive predictive value to 100%, accuracy value to 95.2%. Moreover, this combination discovered 7.1% breast cancer more. Conclusion: US-CNB is a safe and less traumatic diagnostic tool with high pathologic efficiency. Combining mammography and US-CNB increases the diagnostic value. Key words: Breast tumor, breast cancer, mammograms

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