scholarly journals Utility of urine reagent strips in rapid bedside diagnosis of bacterial meningitis

2020 ◽  
Vol 8 (8) ◽  
pp. 2947
Author(s):  
Nanda Patil ◽  
Sujata Kanetkar ◽  
Garima Agarwal ◽  
Supriya Karmakar
Keyword(s):  
Bacterial Meningitis ◽  
Prospective Study ◽  
Tertiary Care ◽  
Rapid Diagnosis ◽  
Csf Analysis ◽  
Bedside Test ◽  
Therapeutic Decisions ◽  
Reagent Strips ◽  
Set Up ◽  
Urine Reagent Strips

Background: Bacterial meningitis is a medical emergency and late diagnosis and treatment can lead to neurological damage and death. For definitive diagnosis of meningitis, laboratory based CSF analysis is required which is based on microscopy, protein and sugar estimation. This requires laboratory set up with experienced pathologist and long turn around time. Hence urinary reagent strips as a semiquantitative method can be applied for CSF analysis. This method can be used where laboratory set up is not available as well as bedside test for early diagnosis of bacterial meningitis. The present prospective study was undertaken to evaluate the utility of urine reagent strips in rapid diagnosis of bacterial meningitis. The aim of the present was to evaluate the role of urine reagent strips in the analysis of cerebrospinal fluid in suspected cases of meningitis.Methods: The prospective study was carried out in the department of pathology in a tertiary care centre for a period of 6 months from September 2018 to February 2019. CSF analysis of suspected cases of meningitis was done with urine reagent strip as well as with standard laboratory method. The results of both were compared.Results: Out of 79 cases of meningitis, 68.35% cases were of bacterial meningitis. The specificity and sensitivity of CSF analysis with reagent strip was 93.33% and 82.35% respectively, for cell count, 94.4% and 88.2% respectively for proteins and 91.3% and 60.2% respectively for glucose.Conclusions: Semiquantitative analysis of CSF sample with urine reagent strips helps in rapid diagnosis of bacterial meningitis and can be useful to facilitate therapeutic decisions in resource constrained settings.

scholarly journals A two-year study on postmenopausal bleeding at a tertiary institute

2021 ◽  
Author(s):  
Sowmyanarayanan Lavanya ◽  
Swetha Munivenkatappa ◽  
Anthata Jyothsna Sravanthi
Keyword(s):  
Prospective Study ◽  
Tertiary Care ◽  
Age Distribution ◽  
Developed Countries ◽  
Tertiary Hospital ◽  
Care Hospital ◽  
Postmenopausal Bleeding ◽  
Medical Problems ◽  
Set Up ◽  
A Prospective Study

Background: The life expectancy of women shows an increase as a result of which women experience a long postmenopausal phase. Postmenopausal bleeding is a worrisome symptom occurring in 10 % of the women, making them seek a gynaecology opinion at the earliest. Women in developed countries have a predilection for developing endometrial cancer whereas cancer cervix still dominates in the developing countries. This prospective study was carried out on 75 women presenting with postmenopausal bleeding to the gynaecology clinic at a tertiary hospital set up. The study aimed to find the incidence of postmenopausal bleeding, age distribution, causes and different evaluation methods to confirm the diagnosis.Methods: The present study is a prospective study conducted on 75 postmenopausal women reporting with postmenopausal bleeding at the gynaecology clinic at a tertiary care hospital.              Results: Menopause was noted above 45 years in 84% of the patients and 16% were in 40-45 years age. Postmenopausal bleeding was observed in 50-60 years in 56% of women and 30% above 60 years. The medical problems associated were hypertension (20%), diabetes (11%), obesity (22%), hypothyroidism (4%). 53 women had benign causes while 22 had malignancy.Conclusions: Benign lesions of the genital tract are common causes of postmenopausal bleeding. Carcinoma cervix and endometrium classically present with postmenopausal bleed. Strong suspicion, thorough evaluation and early diagnosis improve the quality of life and reduce the morbidity and mortality.

scholarly journals Abnormal uterine bleeding: study among patients in a tertiary hospital in Southern Rajasthan

2021 ◽  
Vol 10 (6) ◽  
pp. 2264
Author(s):  
Harshdeep Jadeja ◽  
Komal Inani Jhanwar
Keyword(s):  
Gold Standard ◽  
Tertiary Care ◽  
Abnormal Uterine Bleeding ◽  
Tertiary Hospital ◽  
Rapid Diagnosis ◽  
Uterine Bleeding ◽  
Age Group ◽  
Standard Practice ◽  
Diagnosis And Management ◽  
Set Up

Background: Abnormal uterine bleeding is one of the commonest cases seen in gynecology OPD in the country. The incidence is more commonly seen in late adolescence and perimenopausal group of patients. A fair and objective procedural pattern needs to be adopted to ensure that these patients undergo rapid diagnosis and treatment. The Palm-Coein system is considered as the gold standard. The present study aims to ascertain the efficacy of this system in AUB patient diagnosis.Methods: The study involved as sample of 120 subjects who came to the OPD of the institute and consented to be a part of the study. The subjects were examined and relevant data pertaining to their diagnosis and management was recorded. The data was analyzed and reported.Results: The data revealed that menorrhagia was the commonest complaint. The predominant age group was above 40 years, and had a normal radiological profile in most cases. The use of Palm-Coein system proved effective in determining the diagnosis as well setting a procedural mechanism for adequate management.Conclusions: Palm-Coein is an effective modality for diagnosing and managing AUB cases in a tertiary care set up and can be adopted as a standard practice.

scholarly journals Rapid diagnosis of schistosomiasis in Yemen using a simple questionnaire and urine reagent strips

2014 ◽  
Vol 20 (04) ◽  
pp. 242-249 ◽  
Author(s):  
H.K. Bassiouny ◽  
A.A. Hasab ◽  
N.A. El Nimr ◽  
L.A. Al Shibani ◽  
A.A. Al Waleedi
Keyword(s):  
Rapid Diagnosis ◽  
Reagent Strips ◽  
Urine Reagent Strips

scholarly journals A simple approach improving the performance of urine reagent strips for rapid diagnosis of urinary schistosomiasis in Nigerian schoolchildren

2009 ◽  
Vol 104 (3) ◽  
pp. 456-461 ◽  
Author(s):  
Uade Samuel Ugbomoiko ◽  
Victor Dalumo ◽  
Liana Ariza ◽  
Fernando Schemelzer Moraes Bezerra ◽  
Jorg Heukelbach
Keyword(s):  
Rapid Diagnosis ◽  
Simple Approach ◽  
Urinary Schistosomiasis ◽  
Reagent Strips ◽  
Urine Reagent Strips

Cerebrospinal Fluid C-Reactive Protein Measurement--A Bedside Test in the Rapid Diagnosis of Bacterial Meningitis

1990 ◽  
Vol 36 (5) ◽  
pp. 213-217 ◽  
Author(s):  
M. John ◽  
I. S. Raj ◽  
R. Macaden ◽  
T. S. Raghuveer ◽  
M. Yeswanth ◽  
...  
Keyword(s):  
Cerebrospinal Fluid ◽  
Bacterial Meningitis ◽  
Rapid Diagnosis ◽  
C Reactive Protein ◽  
Reactive Protein ◽  
Bedside Test ◽  
Protein Measurement

Rapid diagnosis of bacterial meningitis with reagent strips

The Lancet ◽  
1995 ◽  
Vol 345 (8960) ◽  
pp. 1290-1291 ◽  
Author(s):  
A. Moosa ◽  
M.D. Ibrahim ◽  
H.A. Quortum
Keyword(s):  
Bacterial Meningitis ◽  
Rapid Diagnosis ◽  
Reagent Strips

scholarly journals Role of Clinical Presentations and Routine CSF Analysis in the Rapid Diagnosis of Acute Bacterial Meningitis in Cases of Negative Gram Stained Smears

2014 ◽  
Vol 2014 ◽  
pp. 1-7 ◽  
Author(s):  
Rabab Fouad ◽  
Marwa Khairy ◽  
Waleed Fathalah ◽  
Taha Gad ◽  
Badawy El-Kholy ◽  
...  
Keyword(s):  
Bacterial Meningitis ◽  
Cost Effective ◽  
Accurate Method ◽  
Cross Sectional Study ◽  
Rapid Diagnosis ◽  
Acute Bacterial Meningitis ◽  
Cross Sectional ◽  
Csf Analysis ◽  
Clinical Presentations

Background and Aim.Bacterial meningitis is a lethal, disabling endemic disease needing prompt antibiotic management. Gram stained smears is rapid accurate method for diagnosis of bacterial meningitis. In cases of negative gram stained smears diagnosis is delayed till culture results. We aim to assess the role of clinical presentations and routine CSF analysis in the cost-effective rapid diagnosis of negative gram stained smears bacterial meningitis.Methods.Cross sectional study including 623 acute meningitis patients divided into two groups: bacterial meningitis and nonbacterial meningitis groups. The clinical presentations, systemic inflammatory parameters, and CSF analysis were evaluated and compared in both groups.Results.Altered conscious level, localizing neurological signs, Kernig’s and Brudzinski’s signs together with peripheral leucocytosis (>10.000/mm3), high CRP (>6) together with high CSF protein (>50 gl/dL), CSF neutrophilic count (≥50% of total CSF leucocytic count), and low CSF glucose level (<45 gm/dL) and CSF/serum glucose ≤0.6 were significantly diagnostic in bacterial meningitis patients. From the significant CSF analysis variables CSF protein carried the higher accuracy of diagnosis 78% with sensitivity 88% and specificity 72%.Conclusions.High CSF protein (>50 mg/dL) together with plasma inflammatory markers and CSF cytochemical parameters can diagnose bacterial meningitis in gram stain negative smear till culture results.

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