scholarly journals Study of TORCH infections and its impact on newborn babies and infants: a retrospective study in a tertiary care hospital in Visakhapatnam, Andhra Pradesh, India

Author(s):  
Sai Prabha Chilakala ◽  
Appa Rao P. ◽  
Ramalakshmi K. ◽  
Suresh Babu Chaduvula

Background: TORCH is an acronym for Toxoplasma, others (syphilis), Rubella, Cytomegalovirus and Herpes simplex virus. These are important causes of morbidity and mortality in new-borns, infants and children. Early diagnosis and treatment are essential to reduce the morbidity and mortality.Methods: It was a cross sectional record based retrospective record-based study conducted in King George Hospital, Andhra Medical College, Visakhapatnam, Andhra Pradesh. Samples from clinically suspected cases (newborns and infants) for possible TORCH infections were tested in virology laboratory from January to November 2019 and the samples were collected and tested by EUROIMMUN kit for the respective IgM antibodies and analyzed. Clinical details of newborns and infants were gathered from the patients through telephonic communication.Results: Total number of patients tested were 104 in which 54 (52%) showed positivity in which 36 were positive for CMV, 25 for HSV2, 23 for Rubella, 12 for Toxoplasma and 11 for Varicella zoster infection. Out of 52 positive cases 20.4% were alive and normal, 20% were alive but severely affected, mortality was 16.7%. Out of 16.7% mortalities 22% of deaths were due to nephrotic syndrome. Clinical manifestations include hepato-splenomegaly in 33.3% cases, fever in 30%, low birth weight in 25%, heart disease in 13.7%, microcephaly in 13.7%.Conclusions: Our study showed hepatomegaly, fever and low birth weight as common clinical manifestations. Fever and nephrotic syndrome were typically associated with CMV positive cases. Out of 52 % positively tested cases CMV was very common infection followed by HSV2, Rubella and Toxoplasmosis.

Author(s):  
Renu Sulakhe Vasant ◽  
Lavanya K. M. Rao ◽  
Nageswara Rao V.

Background: Low birth weight (LBW) is one of the commonest cause for infant and childhood morbidity and mortality. The majority of low birth weight in developing countries is due to intrauterine growth retardation, while most low birth weight in industrialized countries is due to preterm birth. LBW is the single most important factor determining the survival chances of the child. The objectives of the study were to assess the proportion of low birth weight among babies delivered by mothers at a tertiary care hospital and to analyse the relationship between low birth weight and certain socio-demographic factors.Methods: A cross-sectional study conducted in a tertiary care centre for a period of six months.Results: The prevalence of LBW was 23.5%. The proportion of mothers having low birth weight was maximum in women aged less than 18 years (35%) and more than 30 years (26.5%). Muslim women had a higher proportion of LBW (28.8%). LBW was more in women belonging to joint family (30.0%), low per capita income group and illiterates.Conclusions: The prevalence of LBW still continues to be high, almost one fourth of the babies are LBW. Different socio-demographic characteristics of the population are still the important factors determining the occurrence of LBW.


Author(s):  
Pradip Kumar Bhue ◽  
Himansu Prasad Acharya ◽  
Subrat Kumar Pradhan ◽  
Pratima Biswal ◽  
Amit Pritam Swain ◽  
...  

Background: World Health Organization has defined low birth weight (LBW) as birth weight less than 2,500 grams. Giving birth to a LBW infant is influenced by several factors. Objective of the study was to measure the proportion of low birth weight babies delivered in V.S.S medical college and hospital, Burla and its association with socio-demographic factors.Methods: Hospital based cross -sectional study comprising of 1030 postnatal women who delivered single live baby in V.S.S Medical College and Hospital, Burla. Selection of study participants was done by systematic random sampling in the study period October 2012 to September 2014. Chi-square test was used to measure association between LBW and socio-demographic factors.Results: The proportion of LBW was found to be 27.76%. The proportion of LBW babies was high and significant in extremes of age i.e. teenage (44.19%) and 30 years and above age group (39.56%) and Muslim mothers (36.36%), illiterate mothers (53.52 %), manual labourer (67.14%), socioeconomic class IV and V (32.98%), consanguinity history (60.58%), smoky fuel (30.02%), consumption of tobacco (49.11%).Conclusions: The proportion of LBW (27.76%) was found to be higher than national average (21.5%).


2020 ◽  
Vol 27 (02) ◽  
pp. 365-370
Author(s):  
Muhammad Younis Tahir ◽  
Iftikhar Ahmad ◽  
Soufia Farrukh

Objectives: To find out the frequency of retinopathy in low birth weight infant presenting at tertiary care hospital, Bahawalpur. Study Design: Cross sectional study. Setting: Department of Ophthalmology, Bahawal Victoria Hospital, Bahawalpur. Period: From July 2018 to December 2018. Material & Methods: Neonatal eye examination was performed for ROP. Results: Total 78 neonates were recruited for present study and ROP was assessed. Mean gestational age of neonates was 32.54 ± 3.79 weeks. Mean weight was 1445.51 ± 517.373 grams. Out of 78 neonates, ROP was observed in 28 (36%) neonates. ROP was found in 27 (42.19%) neonates of premature group and in 1 (7.14%) neonates of at term group. ROP was found in 1 (3.23%), 5 (29.41%) and 22 (73.33%) neonates respectively in weight group 1500-2500 g, 1000-1500 g and <1000 g group. Male neonates were 35 (44.87%) and female neonates were 43 (55.13%). Development of ROP was not significantly (P = 0.248) associated with gender of the neonates. Statistically significant association between ROP and oxygen supplementation was observed with p value 0.021. Conclusion: Results showed higher number of patients with ROP. Association of development of ROP with gestation was highly significant. Oxygen supplementation and oxygen concentration was also associated with ROP. Findings also showed no effect of gender and duration of hospital stay on ROP.


Author(s):  
M. Sheeba Apoorva ◽  
Vimala Thomas ◽  
B. Kiranmai

Background: Birth weight is an important indicator of new born growth, survival and psychosocial development. Globally, more than 20 million are born with low birth weight (LBW) and the prevalence of low birth weight in India is 20%. The study was conducted to find the proportion of low birth weight and the factors influencing the weight of the baby.Methods: A cross sectional study was conducted at Gandhi hospital, Telangana from September to November, 2015 using a semi structured questionnaire among 204 postnatal mothers.Results: Out of 204 live births, 26% were found to be low birth weight. About 44.4% LBW babies are born to teenage mothers and 70% among the mothers with height less than 140 cms. Of the pre-term babies, nearly half of the babies (49.3%) were low birth weight. Around 30.3% of LBW was found with an inter-pregnancy interval of <2 years. About 41.2% of the mothers having complications had low birth weight babies.Conclusions: Nearly one fourth of the newborns were low birth weight. Gender of the child, socioeconomic status, education, gestational age, inter pregnancy interval, medical complications were found to affect the birth weight.


Author(s):  
Priti J. Patale ◽  
Monika S. Masare ◽  
Seema S. Bansode-Gokhe

Background: To study the Epidemiological Factors related with the low Birth weight Babies born in tertiary care Hospital of teaching Medical Institution.Methods: The present study was a cross sectional observational study carried out in the Post Natal ward of Obstetric department of a tertiary care hospital of a metropolitan city, data collection was done from the Mothers of low birth weight babies by conducting face to face interview in the post-natal ward with a predesigned, structured Performa. Data was analyzed using statistical package for social science program.Results: The study showed that most of mothers of the babies were between the age group of 22 to 30 years 87 (58.3%) while 49 (32.8%) were below the age of 21 years and 13(8.7%) were above 30 years of age. Most of the study subjects 70 (47.0%) belongs to the lower socioeconomic status where as 62 (41.6%) and 17 (11.4%) belong to upper lower and middle socioeconomic class respectively. It was observed in the present study that maternal education, socioeconomic status, parity, maternal weight gain during pregnancy, height of the mother, tobacco habits either chewing or smoking, birth order of the baby are the factors, significantly associated with low birth weight of the baby.Conclusions: Socioeconomic development, maternal nutrition, and increasing the use of health services during pregnancy, are all important for reducing LBW. There is need to strengthen the existing maternal services at the basic level of community.


2017 ◽  
Vol 4 (6) ◽  
pp. 2065 ◽  
Author(s):  
Arshiya Rehman Sheikh ◽  
Sushama Subhash Thakre ◽  
Subhash Thakre ◽  
Chaitanya Rangangouda Patil ◽  
Prithvi B. Petkar

Background: In spite of the interventions being taken, low birth weight still persists as a public health problem in low and middle-income countries. World Health Organization defines low birth weight as birth weight less than 2500 gm. There is a constant search to find newer methods to detect low birth weight babies so that early methods can be instituted. This study was conducted to evaluate calf circumference as procedure to screen low birth weight babies in tertiary care hospital in Nagpur. Methods: A cross sectional study was conducted in tertiary care hospital of Nagpur, Maharashtra for a period of 4 months. The study subjects were babies delivered at the hospital. Birth weight was recorded using a digital weighing scale within 24 hours of the delivery. Length, calf circumference, head and chest circumference were measured according to standard guidelines. Results: Majority of mothers were in the age group of 20 to 24 years of age group, were educated up to primary school and belonged to Hindu religion. The mean calf circumference of low birth weight babies was 9.64±1.13 cm and was 10.96±1.01 cm in normal weight babies. The mean values of calf circumference were significantly lower in low birth weight babies (p <0.001). The sensitivity and specificity for the best cut off of calf circumference was found to be 89.97% and 42.86% respectively.Conclusions: Measuring calf circumference was found to be a good test with higher sensitivity but lower specificity. Hence, calf circumference can be used as an alternative method to screen babies born in remote areas, where the facility of weighing the baby at birth is not available.


Author(s):  
Muhammad Parial Shahani ◽  
Mohd Rizal Abdul Manaf ◽  
Azimatun Noor Aizuddin ◽  
Aneela Atta Ur Rahman ◽  
Saeed Ahmed Shaikh ◽  
...  

In comparison to other middle-income countries, Pakistan has a high prevalence of low birth weight.  Currently the situation has worsened because of the COVID-19 pandemic where stress can have a negative impact on intrauterine development, leading to a rise in preterm birth rates and the incidence of low birth weight babies. The goal of this study is to estimate the prevalence of low birth weight in a tertiary care hospital in Larkana, Sindh, Pakistan, during the COVID-19 pandemic. In this cross-sectional study, the hospital records of two thousand, two hundred and seventy eight neonates were analyzed from patients’ data register for the year 2020. Data were analyzed using Microsoft Excel spread sheet. Of 2278 children admitted to the neonatal ward, only 29.2% babies had birth weight within normal range, 0.7% neonates were high birth weight, and the rest of the admitted babies (70.1%) during the year 2020 had birth weight below 2500 grams. Smallest birth weight observed in the study was 0.9 kg and 4.8 kg was highest birth weight (mean 2.35 kg, SD 0.88, SE 0.012). Female neonates were 895 (39.3%) and the rest of the 1383 (60.7%) babies were male. This study revealed that in Sindh province of Pakistan, the prevalence of low birth weight is extremely high during COVID-19 pandemic. Therefore, the findings suggest that there is need for a lot more emphasis on improving maternal mental health, nutrition and several other relevant factors to reduce the prevalence of low birth weight.


Author(s):  
Pamulaparthi Bindu Reddy ◽  
Gurram Swetha Reddy

Background: Placenta previa refers to the presence of placental tissue that extends over the internal cervical os.  Placenta previa is linked to maternal hypovolemia, anaemia, and long hospital stay and with prematurity, low birth weight, low APGAR score in newborn. So it is very important to identify the condition at an early date to warn the condition thereby reducing the maternal and foetal morbidity and mortality. The present study was aimed to estimate the prevalence of PP, its associated predisposing risk factors and maternal morbidity, mortality and the perinatal outcome.Methods: A prospective observational study for two years was conducted at a tertiary care hospital. Pregnant mothers with >28 weeks of age with H/o ante partum haemorrhage were screened for placenta previa, confirmed by ultra sonography and included in the study. Clinical history, obstetric examination was done and followed up till the delivery. Maternal and foetal outcomes were recorded. Data analyzed by using SPSS version 20.Results: 1.4% incidence of PP was noted, mean age of group was 29.17±1.6 years. Age group of 21-30 years, multiparity Gravida 2-4, previous history of caesarean section and less number of ante natal checkups were significant risk factors and LSCS was most common outcome. Prematurity, low birth weight and APGAR <7 score for 1 minute was common foetal outcomes.Conclusions: Our study strongly suggests foetal surveillance programmes in cases of placenta previa. Measures should be made to bring awareness about PP, in urban slums and to increase medical checkups regularly. Making USG mandatory during every ANC and referral of cases of PP to tertiary care centres would definitely reduce the chances of morbidity and mortality.


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