scholarly journals A clinical study on conservative management of acute appendicitis in a tertiary care centre

2021 ◽  
Vol 8 (4) ◽  
pp. 1190
Author(s):  
Bhanu Bharath Naik
Keyword(s):  
Conservative Treatment ◽  
Acute Appendicitis ◽  
Clinical Symptoms ◽  
Tertiary Care ◽  
Tertiary Care Centre ◽  
Alvarado Score ◽  
Uncomplicated Appendicitis ◽  
Laboratory Investigations ◽  
Modified Alvarado Score ◽  
Uncomplicated Acute Appendicitis

Background: Acute appendicitis is the most common clinical entity which is treated surgically by appendectomy. In recent years acute uncomplicated appendicitis can also be managed non surgically with antibiotic therapy. Aim and Objective was to assess the outcome of conservative treatment in the management of acute appendicitis.Methods: All patients who were diagnosed as acute appendicitis radiologically were enrolled into the study considering inclusion and exclusion criteria. Modified Alvarado score (MAS) was calculated based on clinical symptoms, signs and laboratory investigations. Injection ceftriaxone and injection metronidazole was given for 48-72 hours. Patients who responded for i.v. antibiotics were switched to tablet ciprofloxacin and tablet metronidazole for 7 days and followed for 6 months. Patients who didn’t respond to conservative treatment or had recurrence were classified as treatment failure/recurrence.Results: Totally 100 patients were enrolled in the study, 43 males and 57 females with a ratio of 1:1.32. Majority were in age group of 21-30. Ultrasound was performed in 91 patients, CT scan in 9 patients. 28 patients had MAS between 4-6 and 72 had between 7-9. 82 patients were successfully managed conservatively. 12 patients had failure of conservative treatment and 6 patients had recurrence.Conclusions: Success rate of conservative treatment in patients with MAS 4-6 was more than those with MAS 7-9 in this study. Complicated acute appendicitis should be managed surgically and uncomplicated acute appendicitis can be managed by conservative treatment provided they are strictly followed every month for 6 months to detect recurrences.

scholarly journals Study of conservative treatment in uncomplicated acute appendicitis

2017 ◽  
Vol 4 (4) ◽  
pp. 1409 ◽  
Author(s):  
B. S. Gedam ◽  
Ajit Gujela ◽  
Prasad Y. Bansod ◽  
Murtaza Akhtar
Keyword(s):  
Conservative Treatment ◽  
Acute Appendicitis ◽  
Treatment Failure ◽  
Tertiary Care ◽  
Operative Management ◽  
Care Hospital ◽  
Alvarado Score ◽  
Modified Alvarado Score ◽  
Uncomplicated Acute Appendicitis ◽  
Non Operative Management

Background: Management of acute appendicitis with antibiotics only, without surgery is currently evaluated. Non-operative management of uncomplicated acute diverticulitis and salpingitis has been well established but the non-operative management of acute appendicitis remains controversial. Growing evidence indicates that patients with acute uncomplicated appendicitis can be treated safely with an antibiotics- first approach.Methods: A tertiary care hospital based longitudinal study with duration of 26 month. Patients with clinical and radiological feature of acute appendicitis presenting within 48 hours of initiation of abdominal pain with Modified Alvarado Score ≥5 included. Various demographic, clinico-pathological, radiological factors were studied.Results: 71 patients evaluated, mean age of 30.45±9.71 years. Tenderness in RIF was the commonest finding followed by Fever and rebound tenderness. Leucocytosis seen in 74.65% Modified Alvarado score of 5-6 was present in 18.32% whereas 7-9 was present in 81.68% patients. USG was suggestive of appendicitis in 84.50% patients. Conservative treatment was successful in 74.65% patients with no treatment failure. 25.35% patients, conservative treatment failed. Overall recurrence was seen in 13.11% cases that were successfully managed during primary admission.Conclusions: Majority of cases of first attack of uncomplicated acute appendicitis can be treated successfully by conservative treatment. However, conservative treatment requires monitoring and repeated re-evaluation to identify failure which needs to be treated promptly by surgery. Treatment failure on primary admission as well as the short- term recurrence after conservative treatment is low and acceptable. The outcome of conservative treatment does not depend on Modified Alvarado Score.

scholarly journals Evaluation of conservative management in uncomplicated acute appendicitis

2021 ◽  
Author(s):  
Vignesh M. ◽  
Rajkumar Chejara ◽  
S. V Arya ◽  
Ankit Bhatia ◽  
Rohit Chaudhary ◽  
...  
Keyword(s):  
Standard Deviation ◽  
Conservative Treatment ◽  
Acute Appendicitis ◽  
Conservative Management ◽  
Significant Proportion ◽  
Alvarado Score ◽  
Intravenous Antibiotics ◽  
Uncomplicated Appendicitis ◽  
Uncomplicated Acute Appendicitis

Background: Appendectomy has been the treatment for acute appendicitis for years based on the understanding that acute appendicitis always leads to perforation and peritonitis. However, there is growing evidence that a significant proportion of patients can be successfully managed with conservative treatment without developing gangrene or perforation. Conservative treatment avoids discomfort, surgery-related morbidities and minimizes treatment cost.Methods: 60 patients taken up for conservative management were evaluated and followed up for 6 months. Study patients received intravenous antibiotics for 2 days. Repeated clinical and TLC monitoring were done. In patients whose clinical condition did not improve, appendectomy was performed. Follow-up at 10 days, 30 days, 3 months and 6 months were carried out to assess recurrence in conservatively managed patients.Results: In this study, the mean age was 25.65 years with a standard deviation of ±8.96 years. The incidence of uncomplicated appendicitis was 63.3% in males and 36.7% in females. Mean Alvarado score was 7.75 with a standard deviation of ±1.20. Failure of conservative management (conversion to appendectomy) was observed in 11.7% of patients and 4 patients (6.6%) had recurrence within 6 months. The overall treatment efficacy was 81.7%.Conclusions: In many cases, first attack of uncomplicated acute appendicitis can be treated successfully by conservative management. Treatment failure on primary admission as well as short-term recurrence up to six months after conservative treatment is low and acceptable. Incidence of complications like perforation and abscess formation are also statistically low.

scholarly journals Prevalence of perforated appendicitis and its determinants in pediatric appendicitis patients admitted in tertiary care centre, South India: a cross sectional study

2018 ◽  
Vol 5 (12) ◽  
pp. 3926
Author(s):  
Chandrashekar S. ◽  
Lokesh M. G. ◽  
Avinash S. R.
Keyword(s):  
Acute Appendicitis ◽  
Tertiary Care ◽  
Perforated Appendicitis ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Tertiary Care Centre ◽  
Alvarado Score ◽  
Cross Sectional ◽  
Pediatric Age Group ◽  
Perforated Appendix

Background: Appendicitis remains a common indication for urgent surgical intervention in pediatric age group. Acute appendicitis has the highest incidence during the second decade of life. When the diagnosis is performed, perforation could be already present in 30%-75% of children, with young children being at higher risk. The challenge for the practitioner is to perform a timely diagnosis of acute appendicitis in first years of life before complications occur.Methods: A facility based cross sectional study was conducted with sample size of 108. The patients diagnosed and operated for acute appendicitis using Alvarado score were correlated with intra operative findings.Results: Total 108 patients with median age of 11 (IQR 9–13) years, were included in the study in which 66% were male. Overall 18% (95% CI 11%-25%) had perforated appendix and 5% (95% CI 2%-11%) had appendicitis with abscess. Male gender, patients presenting with fever, guarding, rigidity and patients presenting 48 hours after developing symptoms, had higher chance of perforation. Mean count of WBC (17000 v/s 11000) and neutrophils (75% v/s 68%) were found to be higher in patients with perforated appendicitis.Conclusions: One-fifth of the pediatric appendicitis patients presenting in tertiary care patients had perforated appendicitis.

scholarly journals Leucocyte count in children with complicated and uncomplicated acute appendicitis: a comparative study

2019 ◽  
Vol 6 (12) ◽  
pp. 4308
Author(s):  
Liya Joseph
Keyword(s):  
Acute Appendicitis ◽  
Leucocyte Count ◽  
Tertiary Care ◽  
Age Groups ◽  
Complicated Appendicitis ◽  
Total Leucocyte Count ◽  
Chi Square ◽  
Uncomplicated Appendicitis ◽  
Uncomplicated Acute Appendicitis ◽  
Complicated Acute Appendicitis

Background: Identification of complicated and uncomplicated acute appendicitis is important in children. In acute appendicitis, along with clinical evaluation and staging, many laboratory tests have been used. The aim of the study was to compare total leucocyte count in children with uncomplicated and complicated acute appendicitis in different age groups.Methods: Retrospective cohort study was performed in children who underwent appendicectomy, in a Government tertiary care institution between January 2017 and December 2018. 206 patients were divided into complicated and uncomplicated appendicitis. Total leucocyte count at time of admission was compared according to age. Unpaired t test and Chi-square test were used for statistical analysis.Results: There were 136 males and 70 females. 107 patients (51.94%) had complicated and 99 (48.06%) had uncomplicated appendicitis. Mean leucocyte count per µl in uncomplicated appendicitis was 18993±3540 in <5 years, 17155±3386 in 5-10 years and 15833±3613 in 10-15 years. The mean leucocyte count for complicated appendicitis was 19974±3658 in <5 years, 17727±4487 in 5-10 years and 17220±3411 in 10-15 years age group. In 10-15 years group, patients with complicated acute appendicitis had statistically significant higher values of mean total leucocyte count.Conclusions: Total leucocyte count can be used as marker of severity of acute appendicitis in children older than 10 years. In children with clinical suspicion of acute appendicitis, total leucocyte count >20000 per µl signifies complicated appendicitis in all age groups.

EVALUATION OF MODIFIED ALVARADO SCORE IN DIAGNOSIS OF ACUTE APPENDICITIS AT TERTIARY CARE HOSPITAL IN WESTERN RAJASTHAN

2020 ◽  
Vol 4 (2) ◽  
Author(s):  
Anil Kumar Dadhich ◽  
Atul Kumar Sharma
Keyword(s):  
Acute Appendicitis ◽  
Acute Abdominal Pain ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Care Hospital ◽  
Alvarado Score ◽  
Common Complaint ◽  
Emergency Department Patients ◽  
Modified Alvarado Score ◽  
High Degree

Background: Acute abdominal pain is a common complaint among emergency department patients. Methods:  A 100 consecutive patients suspected of acute appendicitis who were admitted in department of surgery. They were prospectively evaluated using the modified Alvarado scoring (MAS) to determine whether or not they had acute appendicitis. Result: In present study, out of total 100 patients 78(78%) were have MAS score 7-9, 20% were have 5-6 and 2% have MAS score 1-4. Conclusion: The study shows that use of MASS in patients suspected to have acute appendicitis provides a high degree of diagnostic accuracy. Keywords: Modified Alvarado Score (MAS), acute appendicitis, Patients.

scholarly journals A Clinicopathological Review of 655 Appendices Removed For Acute Appendicitis in a Tertiary Care Medical Center in Lebanon: A Retrospective Study

2019 ◽  
Vol 3 (2) ◽  
Keyword(s):  
Acute Appendicitis ◽  
Medical Center ◽  
Tertiary Care ◽  
Perforated Appendicitis ◽  
Tertiary Care Centre ◽  
Female Ratio ◽  
Tertiary Care Medical Center ◽  
Uncomplicated Appendicitis ◽  
Histopathological Studies ◽  
Male To Female

Context: Acute appendicitis is the most commonly performed emergency abdominal surgery. A variety of conditions can mimic it. Aims: This study aims to determine the pathological diagnosis in appendectomy specimens. Methods and Materials: This is a retrospective analysis of 655 patients who underwent appendectomy in a tertiary care centre between January 2007 and February 2018. Demographic information was gathered. The results were analysed using SPSS statistics software. Results: 655 patients were included (male to female ratio: 1.46/1). The mean age was 31.9 years. Histopathological findings were abnormal in 514 (78.4%) including uncomplicated appendicitis 442 (67.4%), perforated appendicitis 26 (3.97%), necrotic gangrenous appendicitis 7 (1.1%), accidental appendicitis 5 (0.76%), purulent appendicitis 4 (0.6%), congestion 11 (1.67%), fecaloma 8 (1.22%) and unusual findings in 13 patients. The perforation rate was 7.6%. Patients with pathologically normal appendices were significantly older than those with abnormal appendices (P<0.05). Abnormal findings were more seen in males (p<0.05). The false appendectomy rate for appendicitis was 12.8% (75 cases), Gender was determined to have a significant effect on this rate (P<0.05) which was more seen in females (60%) while age had no effect on it. Conclusion: The variety of pathological results post appendectomy verifies the continuous need for histopathological studies to confirm the diagnosis. False appendectomy rate is more common in females which suggest the need of laparoscopy in this group.

scholarly journals A comparative study on RIPASA and modified Alvarado score in the diagnosis of acute appendicitis in tertiary care hospital

2021 ◽  
Vol 8 (3) ◽  
pp. 944
Author(s):  
Kodenge Raghavendra Rao ◽  
D. Navya Sesha Harika ◽  
Suragani V. Narayana ◽  
Vinodh Kumar K. S. ◽  
Chavala Pavan Kumar Yadav ◽  
...  
Keyword(s):  
Acute Appendicitis ◽  
Scoring System ◽  
Iliac Fossa ◽  
Tertiary Care ◽  
Scoring Systems ◽  
Care Hospital ◽  
Alvarado Score ◽  
Modified Alvarado Score ◽  
Sensitivity Specificity ◽  
Ripasa Score

Background: Acute Appendicitis is common surgical emergencies with a lifetime prevalence of approximately 1 in 7. Despite advances in diagnosis and treatment; acute Appendicitis is still associated with morbidity (10%) and mortality (1-5 %). Presentations of acute Appendicitis can mimic various acute medical and surgical conditions, and the diagnosis is predominantly a clinical one-different scoring systems used for aiding in early diagnosis of Acute Appendicitis and its prompt management. Alvarado score and RIPASA score are the most popular ones. So we retrospectively applied and compared Alvarado and RIPASA score in the diagnosis of acute Appendicitis in Indian population.Methods: In this study, we compared RIPASA score and Alvarado scoring system retrospectively by applying to 74 patients. This study period from November 2018 to March 2020. Both scores were calculated for patients presented with right iliac fossa pain. Sensitivity, specificity, positive predictive value (PPV), negative predictive (NPV), diagnostic accuracy for RIPASA and Alvarado system was calculated.Results: The sensitivity and specificity of the Alvarado score were 85.07% and 57.14% respectively. The sensitivity & specificity of RIPASA score were 91.04% and 71.42% respectively. Accuracy of the Alvarado scoring system is 82.44% and for RIPASA scoring system is 89.18%. The results show that the RIPASA scoring system is a better diagnostic tool for the diagnosis of Acute Appendicitis.Conclusions: RIPASA scoring system is simple, accurate, convenient, and more specific scoring system than the modified Alvarado scoring system for the Indian population.

scholarly journals A comparative study to assess efficacy of Tzanakis score and Alvarado score for effective diagnosis of patients with acute appendicitis at a tertiary care centre in North Karnataka: a one-year prospective analytical study

2020 ◽  
Vol 7 (6) ◽  
pp. 1742 ◽  
Author(s):  
Dron Sharma ◽  
R. S. Koujalagi
Keyword(s):  
Acute Appendicitis ◽  
Sensitivity And Specificity ◽  
Predictive Value ◽  
Tertiary Care ◽  
Negative Appendectomy ◽  
Medical Procedure ◽  
Tertiary Care Centre ◽  
Alvarado Score ◽  
One Year ◽  
Effective Diagnosis

Background: Acute appendicitis standout amongst the most widely recognized reasons for intense stomach torment. There is no ideal symptomatic assessment apparatus to distinguish acute appendix if indications are ambiguous, bringing about longer analytic procedure and it might prompt deferring of medical procedure and related increment in morbidity and fatality. In the meantime, speedy management may prompt negative appendectomy with expanded morbidity and consumption of healthcare resources.Methods: A Hospital based one year prospective study was conducted at KLEs Dr Prabhakar Kore Hospital Belagavi, Karnataka from 1st January 2018 to 31st December 2018 and required data was collected from 100 patient who were clinically diagnosed to have acute appendicitis and all patients were assessed using Alvarado score and Tzanakis score and HPR for all patients were used as gold standard to evaluate the efficacy of both scoring systems.Results: The sensitivity and specificity of Tzanakis score was 80.6% (at score >8) and 100% (at score >8) respectively.  positive predictive value in present study being 100% and negative predictive value being 41.3%. The sensitivity and specificity of Alvarado score was 11.3% (at score >8) and 100% (at score >8) respectively.Conclusions: Tzanakis Score outperformed Alvarado score displaying higher sensitivity with similar specificity.

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