scholarly journals A study of gross congenital malformation at birth

2019 ◽  
Vol 6 (3) ◽  
pp. 1019
Author(s):  
Pooja R. Gandhi ◽  
Hetal D. Vora ◽  
Halak J. Vasavada ◽  
Mehul T. Patelia ◽  
Pragneshkumar L. Popatiya ◽  
...  

Background: A congenital anomaly is a structural anomaly of any type that is present at birth. Congenital anomalies may be induced by genetic or environmental factors. Most congenital anomalies, however, show the familial patterns expected of multi-factorial inheritance. The aims and objective of this study were to study the incidence of visible congenital malformations at birth, to study risk factors, to find associated internal malformations.Methods: It is a retrospective cross-sectional study carried out in a tertiary care hospital affiliated to a medical college. The Inclusion criteria include all new-borns delivered in the hospital with visible congenital malformations examined within 48 hours of birth. Extramural babies were included if they had presented within 48 hours after birth. The Exclusion criteria include still births were excluded from the study.Results: Percentage of congenital malformation was 1.32%. Most common systems involved were musculoskeletal system (46.34%) followed by genitourinary system (21.34%) and gastrointestinal system (14.02%).Conclusions: All Babies with gross congenital malformation should be screened for internal malformation. The incidence of CNS malformation has reduced than observed in previous studies which suggest awareness about antenatal folic acid supplementation. Other than CNS anomalies, other system anomalies were not diagnosed antenatally despite antenatal ultrasound being done in maximum number of mothers, which suggest use of 3D or 4D scan antenatally.

Author(s):  
Kangjam Radhesana Devi ◽  
R. K. Praneshwari Devi ◽  
Jyoti Priya ◽  
Ahanthembi Sanaton ◽  
Leimapokpam Roshan Singh ◽  
...  

Background: Congenital anomalies are important cause of morbidity and mortality in newborns and are defined as structural and functional abnormalities including metabolic disorders present at birth. These defects are of prenatal origin resulting from defective embryogenesis or intrinsic abnormalities in the process of development and are associated with various risk factors.Methods: Our study is a cross-sectional study done at Regional Institute of Medical Sciences, Imphal over period of one and half years from May 2016 to October 2017. Aim of study was to find out incidence of congenital anomalies and proportions of different types of congenital anomalies. Outcome was studied in relation to maternal age, religion, parity, gestational age, sex of baby, outcome and birth weight of baby.Results: Total numbers of congenital anomalies were 91 out of 13658 births. Incidence of congenital anomalies was 0.66%. Most common congenital anomaly was cleft lip (17.6%) followed by CTEV (13.2%) and was more common among male term babies. These were most common in 18-24 years of maternal age group (34.1%) followed by 30-34 years (26.4%) and among women of parity P0-P2.Conclusions: Congenital malformations are a major cause of still births and infant mortality. A level II targeted scan should be done at 18-20 weeks to find out anomalies and reduce the prevalence. There should be widespread education in the community regarding the common congenital malformations, their outcomes and possible available modes of treatment. 


Author(s):  
R. K. Praneshwari ◽  
N. Nabakishore Singh ◽  
Akoijam Tamphasana Devi ◽  
Jyoti Priya ◽  
L. Ranjit Singh

Background: Congenital anomalies are important cause of morbidity and mortality in newborns and are defined as structural and functional abnormalities including metabolic disorders present at birth. These defects are of prenatal origin resulting from defective embryogenesis or intrinsic abnormalities in the process of development and are associated with various risk factors.Methods: Our study is a cross sectional study done at Regional Institute of Medical Sciences, Imphal over period of 3 years from January 2015 to December 2017. Aim of study was to find out incidence of congenital anomalies and proportions of different types of congenital anomalies. Outcome was studied in relation to maternal age, religion, parity, and gestational age, sex of the baby, outcome and sex of the baby.Results: Total numbers of congenital anomalies were 257 babies out of 29879 births giving the incidence of 0.86%. Most common congenital anomalies in this study are musculoskeletal followed by craniospinal, genitourinary, cardiovascular and gastrointestinal. It was more common in preterm babies and parity 1-3, more common in 21-30 years of maternal age. Consanguinity was seen in 7 out of 257 patients.Conclusions: Congenital malformations are a major cause of still births and infant mortality. Targeted scan should be done at 18-20 week to find out anomalies and reduce the prevalence. There should be widespread education in the community regarding the common congenital malformations, their outcomes and possible available mode of treatment


2019 ◽  
Vol 6 (6) ◽  
pp. 2364
Author(s):  
Vikram V. Yaragatti ◽  
Shivanagouda .

Background: Congenital malformations are emerging as an important perinatal problem, contributing sizably to the perinatal mortality with considerable repercussions on the mothers and the families. Patients with multiple congenital anomalies present a relatively infrequent but tremendously difficult challenge to the pediatrician. Authors objective was to study the incidence of clinically detectable congenital malformations among consecutive births in hospital deliveries examined during hospital stay.Methods: A prospective cross sectional study was conducted in Department of Pediatrics at Dr R N Cooper Municipal General Hospital, Mumbai from June 2016 to June 2017. All live births from June 2016 to June 2017 were considered in the studyResults: The total number of deliveries in our hospital were 3120(100%) and the total number of babies with congenital anomaly were 43(1.4%), So the incidence of congenital anomalies amongst study population was 1.4%. The involvement of various systems was seen in our study. The involvement of CNS (9.3%), Eye (7%), ENT (28%), GIT (20.9%), Urinary Tract (2.3%), Musculoskeletal System (35%), Gentialia (7%), CVS (7%).Conclusions: Congenital malformation, one of the important causes of infant mortality and morbidity can be reduced by proper preconception care and level two anomaly scan. Congenital anomalies must be identified, as early diagnosis and surgical correction of malformed babies offer the best chance for survival.


2021 ◽  
pp. 12-15
Author(s):  
Smarajit Banik ◽  
Sandip Saha ◽  
Sudipan Mitra ◽  
Ujjwal Pattanayak ◽  
Rajib Sikder ◽  
...  

Background: Diabetes mellitus is one of the important causes of morbidity and mortality. With a rise in non communicable diseases in India, diabetes has become a modern epidemic showing a rising trend in West Bengal also. A large number of diabetes patients come to the diabetes clinic of our tertiary care hospital in North Bengal Medical College and Hospital, Darjeeling, West Bengal. The large proportion of patients presenting with this condition prompted us to study the Sociodemographic and Anthropometric Prole of such patients. Methods: This was a descriptive hospital based cross sectional study involving a total of 344 diabetic patients enrolled in the diabetes clinic of a tertiary care teaching hospital from December 2019 to February 2020. A self-administered questionnaire was used to collect data and was analyzed in Microsoft excel sheet and using SPSS 20.0 software. Results: Among the 344 study participants, we found that 220 (63.95%) were males and 124 (36.05%) were females. Diabetes was more common among those aged 51-60 years 108 (31.40%). Family history was present among 188 (54.65%) of the diabetic patients. Almost 160 (46.51%) patients have diabetes 1.1 – 5 years. Hypertension was present among 216 (62.79%) patients. Almost 218 (63.37%) of the patients were overweight and 84 (24.42%) were obese. Conclusions: The diabetic patients presenting to this tertiary care hospital belong lower socioeconomic strata and having limited education in their age group. There is high proportion of obesity and hypertension among them.


2013 ◽  
Vol 3 (1) ◽  
pp. 29-31
Author(s):  
Swapna Bhattacharjee ◽  
Shekhar Bhattacharjee ◽  
Rukhsana Parvin

Background: Cough variant asthma (CVA) is a subset of asthma where the only symptom is chronic persistent cough. Many cases go unrecognized due to lack of proper evaluation. Response to asthma medication with features supportive of airway hypersensitivity helps in management of this disease. Objective: To find out the proportion of cough variant asthma among the patients attending medicine outpatient department of Enam Medical College, Savar, Dhaka. Materials and Methods: This cross sectional study was conducted in Enam Medical College Hospital, Savar, Dhaka over a period of two years from July 2009 to July 2011. Cough variant asthma was diagnosed mainly on clinical ground as chronic cough without wheezing, fever, weight loss, shortness of breath or sputum or any other apparent cause that persisted for more than eight weeks with absolutely normal physical examination of chest, normal chest radiography and blood count except raised eosinophil count and IgE level. Patients who met these criteria were given 2 weeks course of inhaler beclomethasone propionate and were assessed for improvement. Those who improved after steroid inhalation were categorised as having cough variant asthma. Results: Out of purposively selected 148 patients complaining only of chronic dry cough for more than eight weeks, 92 patients met the primary selection criteria for cough variant asthma. These 92 patients were given 2 weeks trial of 250 ìgm beclomethasone inhalation twice daily. Seventy nine patients reported almost complete recovery from chronic cough after 2 weeks and were categorized as having CVA. Thirteen patients did not improve and were not categorized as CVA. Conclusion: These findings suggest that cough variant asthma is the most common among the patients with chronic cough not due to any apparent cause. The efficacy of inhaled corticosteroid suggests that early intervention is effective in the treatment of this disease. DOI: http://dx.doi.org/10.3329/jemc.v3i1.13871 J Enam Med Col 2013; 3(1): 29-31


2021 ◽  
pp. 63-71
Author(s):  
Kangjam Radhesana Devi ◽  
R. K. Praneshwari Devi ◽  
Jyoti Priya ◽  
Ahanthembi Sanaton ◽  
Leimapokpam Roshan Singh ◽  
...  

Author(s):  
Gayatri Aseri ◽  
Sudesh Agrawal

Background: This study was carried out to assess the knowledge, attitude, and practice of contraceptive methods among women attending a tertiary care hospital in Western Rajasthan.Methods: This cross-sectional study was conducted in the department of obstetrics and gynecology, PBM and the associated group of hospitals, attached to Sardar Patel Medical College, Bikaner, Rajasthan, India. Total 500 married women between age group 15-49 yrs were included. These all women interviewed using a structured questionnaire after approval of the hospital’s ethical committee.Results: Total 500 women interviewed for their knowledge, attitude, and practices about contraception. Out of which, 402 (80.4%) women had some knowledge of at least one contraception method at the time of the study.  The most common sources of information about contraception were husband and family member. Amongst the various contraceptives most commonly known was condom (78.4%). Only 265 (53%) women were practicing contraception at present. Most commonly used contraceptive was condom (40.8%). The most common reason for the non-practice of contraception was need of more child or male child in 34.8% families followed by opposition from in-laws (12.4%).Conclusions: Literacy was positively associated with family planning related knowledge and practices. Preconception knowledge and practices about contraception are poor in our study population. Many of the women were getting MTP pills over the counter without consulting to health care persons and then later presents with complications.


2020 ◽  
Vol 7 (1) ◽  
pp. 12-17
Author(s):  
Anika Tasnim ◽  
AKM Shamsuzzaman ◽  
Md Shah Alam ◽  
Jannatul Ferdose ◽  
Fazlay Akbar Khan

Background: Patients of burn wound are generally more susceptible to infection due to concurrent status of malnutrition and immunosuppression. Among many bacteria, MRSA has appeared as a challenging pathogen irrespective of effective antibiotic therapy. Objective: The purpose of the present study was to detect the prevalence and antibiogram of MRSA in burn wound infected patients. Methodology: The present cross sectional study was conducted at Department of Microbiology in Rajshahi Medical College, Rajshahi, Bangladesh. The samples were collected from Burn and Plastic Surgery Unit of Rajshahi Medical College Hospital, for a period of one year. Phenotypic detection of MRSA were done by cefoxitin disc diffusion method and genotype (mecA gene) was detected by PCR which was conducted at Dhaka Medical College, Dhaka among all the S. aureus isolates. Result: A total of 212 wound swabs were subjected to bacteriological culture media for isolation of MRSA and other organisms. As a whole 89.62% samples yielded growth in culture of which Pseudomonas aeruginosa was the predominant pathogen (34.18%). Out of 21 S.aureus isolates, 07(33.33%) were detected as MRSA by cefoxitin resistance and presence of mecA gene. Although over 85% MRSA were resistance to ciprofloxacin and ceftriaxone, but the present study could not detect any vancomycin resistant MRSA. Conclusion: The high prevalence and decreased sensitivity of MRSA to commonly used antibiotics has been observed in Burn Unit of RMCH. Therefore it is necessary to establish an antimicrobial surveillance system in hospital settings to prevent the spread of MRSA. Bangladesh Journal of Infectious Diseases 2020;7(1):12-17


2014 ◽  
Vol 2 (2) ◽  
pp. 64-67 ◽  
Author(s):  
Tanzima Begum ◽  
Md Ismail Khan ◽  
Shamima Kawser ◽  
Md Ehsanul Huq ◽  
Nadira Majid ◽  
...  

Background: Drug can cure ailment when used rationally on the other hand they may become harmful or even may threaten a life when used irrationally. Absence of guidelines for antibiotic use, protocols for rational therapeutics and infection control committees, have led to overuse and misuse of antimicrobials even in different specialized units in hospitals. Objective: The study has been designed to get a picture of use of antibiotics in a tertiary care hospital of Bangladesh. Materials and method: Cross sectional study was conducted in the department of Medicine of Sir Salimullah Medical College and Mitford Hospital, Dhaka, Bangladesh, for 3 months from 1st January 2009 to 31st March 2009. Admitted patients of Medicine unit-1 who got antibiotics were included in the study. Total number of patients was 1563. Results: Five hundred out of 1563 patients were prescribed antibiotics (38%). Out of 500 prescriptions, 68(14%) prescriptions were found irrational. Conclusion: Continuous surveillance should be carried out to reduce the irrational use of antibiotics. DOI: http://dx.doi.org/10.3329/dmcj.v2i2.20526 Delta Med Col J. Jul 2014; 2(2): 64-67


2013 ◽  
Vol 5 (1) ◽  
pp. 58-62 ◽  
Author(s):  
Archana Angrup ◽  
Thakur Kamlesh ◽  
Jaryal Subhash Chand ◽  
Sood Anuradha ◽  
Chandel Lata

Objectives: The present study addresses this important issue of NSI and aims at determining their occurrence among the nursing staff in Dr Rajendra Prasad Government Medical College (RPGMC) and hospital, Kangra at Tanda (H.P). Methods: A cross sectional study undertaken amongst the nursing staff of Dr RPGMC and hospital, Kangra at Tanda. Results: Out of the 164 respondents, 35(21.3%) reported to having one or more NSIs in their career and the maximum of these were amongst the nurses whose work experience was less than five years (13.4%). Conclusions: The results of this study confirm the importance of the need for an increased awareness of the risk of needlestick injury, the need to provide for the training and education of health-care workers DOI: http://dx.doi.org/10.3126/ajms.v5i1.4971 Asian Journal of Medical Science Vol.5(1) 2014 pp.58-62


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