scholarly journals A prospective study for the assessment of thyroid function by pre and post supervised exercise protocol in newly diagnosed patients of subclinical hypothyroidism

2019 ◽  
Vol 6 (2) ◽  
pp. 253
Author(s):  
Dharmendra Jhavar ◽  
Naresh K. Patel ◽  
V. P. Pandey
Keyword(s):  
Physical Exercise ◽  
Thyroid Function ◽  
Subclinical Hypothyroidism ◽  
Thyroid Function Test ◽  
Exercise Group ◽  
P Value ◽  
Newly Diagnosed ◽  
Function Test ◽  
Thyroid Profile ◽  
Regular Physical Exercise

Background: The presence of raised serum TSH with serum free T4 and T3 within the reference range falls in subclinical hypothyroidism. It is a well-known fact that exercise affects the activity of thyroid glands and the production of their hormones. Author studied the effect of regular exercise in patients of newly diagnosed subclinical hypothyroidism. Pre and post-exercise thyroid function tests were evaluated to decide about the necessity to start thyroid replacement therapy or to adopt wait and watch policy.Methods: Study enrolled 100 newly diagnosed subclinical hypothyroidism patients attending this tertiary care hospital and randomised them in two groups, one group was subjected to regular physical exercise of 45-60 minutes daily along with supervised treadmill exercise stage 0 for 45-60 minutes once weekly followed by re-evaluation of thyroid function test after 30 days and second group was re-evaluated for thyroid function test without exercise after 30 days.Results: Thyroid profile parameters were compared and analysed by paired ‘t’ test, statistically significant increase in serum T3 (p value <0.05) and serum T4 (p value <0.05), along with significant reduction in TSH level (p value <0.05) were found in exercise group, while in non-exercise group changes in thyroid profile parameters were statistically not significant. There was significant reduction in mean weight in exercise group (p value <0.05), while in non-exercise group changes in weight were not significant.Conclusions: Present study concluded that regular physical exercise can improve thyroid function in patients of newly diagnosed subclinical hypothyroidism and convert them to euthyroid state.

scholarly journals Status of Thyroid Disorder among the Thyroid Function Test Samples Received in a Laboratory among Postmenopausal Women: A Descriptive Cross-sectional Study

2021 ◽  
Vol 59 (234) ◽  
Author(s):  
Manoranjan Shrestha ◽  
Reshmi Shrestha
Keyword(s):  
Postmenopausal Women ◽  
Thyroid Function ◽  
Subclinical Hypothyroidism ◽  
Thyroid Dysfunction ◽  
Thyroid Function Test ◽  
Cross Sectional Study ◽  
Reference Laboratory ◽  
Sectional Study ◽  
Cross Sectional ◽  
Function Test

Introduction: Thyroid dysfunction prevalence is high in females worldwide which increases with age. Postmenopausal and elderly women are particularly at risk of developing comorbidities and mortality related to thyroid dysfunction. We aimed to study the prevalence of thyroid dysfunction in postmenopausal women in the National Reference Laboratory of Nepal. Methods: A descriptive cross-sectional study was conducted in National Reference Laboratory from January 2019 to June 2019 including postmenopausal females, ≥49 years. The database of thyroid function test result was used for statistical analysis and proportion of thyroid dysfunction was calculated. The data was collected after approval from the institutional review committee. Statistical Package for Social Sciences version 21 was used to study descriptive data. Results: Out of a total of 160 postmenopausal females with thyroid function tests, 71 (44.4%) had thyroid dysfunction. Subclinical hypothyroidism was the frequently occurring thyroid dysfunction 51 (32%) followed by subclinical hyperthyroidism 13 (8%), hypothyroidism 3 (2%) and hyperthyroidism 3 (2%). In our study population, thyroid dysfunction peaked at 49 to 58 years of age interval 53 (33.1%) and subclinical hypothyroidism was the most frequent form 38 (23.7%). Conclusions: Subclinical hypothyroidism was the common thyroid dysfunction in postmenopausal age which peaked at 49 to 58 years of age group. Early postmenopausal females are predisposed to increased risk of comorbidities (cardiovascular disease, osteoporosis with high fracture, depression) which could be exacerbated with thyroid dysfunction; therefore awareness of thyroid dysfunction prevalence and thyroid screening for early management seems appropriate in Nepalese postmenopausal women.

scholarly journals Thyroid Function Test (TSH, T3, T4) and Associated Factors in Early Gestation Among Pregnant Women Attending ANC Clinic in Nekemte Referral Hospital Western Oromia, Ethiopia.

2020 ◽  
Author(s):  
Regea Dabsu Hirpa ◽  
Worku Dechassa Heyi ◽  
Elias Merdassa Roro
Keyword(s):  
Drinking Water ◽  
Pregnant Women ◽  
Thyroid Function ◽  
Subclinical Hypothyroidism ◽  
Associated Factors ◽  
Health Workers ◽  
Thyroid Function Test ◽  
Referral Hospital ◽  
Early Gestation ◽  
Function Test

Abstract Introduction: Thyroid function testing in pregnancy is an area of concern for pregnant women, doctors and laboratories. Some women are known to have thyroid disease before pregnancy and require monitoring to ensure no harm comes to them or their baby. Thyroid disorders can have adverse reproductive and pregnancy implications. Thus, the aim of this study was to assess blood level of thyroid function test during early gestation and assess associated factors among pregnant women attending antenatal care clinic in Nekemte Referral Hospital.Methods: Facility-based Cross-sectional study design was deployed to collect information from 300 Pregnant women (<20 gestation weeks) attending antenatal clinic from March to May, 2017. Interviewer-administered structured questionnaire was used to obtain information and blood samples were collected from pregnant women for estimation of thyroid function test after getting written consent. Data was entered to Epi info version 3.5.3, cleaned and analyzed using SPSS version 24 and Multivariable analysis were used to examine the association between dependent and independent variables. Odds ratios (ORs) and their 95% confidence intervals (CIs) were calculated. Significance was declared at P-value 0.05.Result: A total of 300 pregnant women were interviewed and blood sample collected from them for thyroid function test with a response rate of 90.1%. Among the study subjects 14(4.7%) have Subclinical Hypothyroidism (SCH). Husband occupation, presence of Radio in the household, presence of television in their house and treating drinking water at household level were among factors associated with development of Hypothyroidism.Conclusion and Recommendation: In this study, Subclinical Hypothyroidism (SCH) among pregnant women in early gestation is significant 14(4.7%) above the expected 2.5% of American thyroid association cut point. Husband occupation, Presence of media for information and treatment of drinking water were the associated factors. So, health workers should always update pregnant women on importance of consuming proper utilization of iodized salt. Health workers shall also teach pregnant women on personal and environmental hygiene.

scholarly journals Association of Thyroid Function Test Abnormalities and Thyroid Autoimmunity With Preterm Birth

JAMA ◽  
2019 ◽  
Vol 322 (7) ◽  
pp. 632 ◽  
Author(s):  
◽  
Tim I. M. Korevaar ◽  
Arash Derakhshan ◽  
Peter N. Taylor ◽  
Marcel Meima ◽  
...  
Keyword(s):  
Preterm Birth ◽  
Thyroid Function ◽  
Thyroid Autoimmunity ◽  
Thyroid Function Test ◽  
Function Test

THYROID CYTOLOGY AND IT'S INTERPRETATION WITH THYROID FUNCTION TEST

2021 ◽  
pp. 80-82
Author(s):  
Dipti Debbarma ◽  
Shipra Singh ◽  
Debarshi Jana ◽  
Chittaranjan Dutta
Keyword(s):  
Thyroid Gland ◽  
Thyroid Function ◽  
Nodular Goiter ◽  
Thyroid Function Test ◽  
Total Serum ◽  
Endocrine Glands ◽  
Nodular Goitre ◽  
Medical College ◽  
Euthyroid State ◽  
Function Test

INTRODUCTION: The Thyroid gland is unique among the endocrine glands. It is the largest of all the endocrine glands and it is supercial in location. It is the only gland which is easily approachable to direct physical, cytological and histopathological examination. The thyroid gland is affected by a variety of pathological lesions that are manifested by various morphologies including developmental, inammatory, hyperplastic and neoplastic pathology which are quiet common in the clinical practice. AIM OFTHE STUDY:In this study, we aimed to assess the cytological ndings of palpable thyroid nodules in conjunction with thyroid hormonal prole of the patient. To study the incidence in relevance to age, sex in various categories of thyroid lesions. MATERIALS & METHODS: Study Design: Institutional based Cross-sectional Study. Duration of study: January 2019 to August 2020. Source of data: Patients presenting to the OPD and admitted in the In-patient ward at Darbhanga Medical College, Bihar. Place of study: Department of Pathology, Darbhanga Medical College and Hospital, Laheriasarai, Bihar. Sample Size: 60 patients of enlarged thyroid gland. RESULTS & OBSERVATIONS: We found that the 53.3% Patients are in euthyroid state. Nodular goitre is the most common nding. In the present study among 60 patients, Nodular goiter accounts for 83.3 % of all cases; 41.7% of them were in euthyroid state, 21.7 % in hypothyroid state , 8.3 % in subclinical hypothyroid and remaining 11.7 % in hyperthyroid state . SUMMARY AND CONCLUSION: FNAC together with thyroid function test (TFT) analysis leads to early and accurate diagnosis of various thyroid diseases and reduces surgical intervention. The study showed that FNAcytologic diagnosis cannot be used to predict thyroid function using total serum T4, T3 and TSH concentrations. Measurement of TSH, free T4, and free T3 would be preferable

scholarly journals The Characteristics of Children with Abnormalities Detected in Thyroid Function Tests, and Distribution of Diagnoses

2020 ◽  
Author(s):  
Elif Çelik ◽  
Ayşe Anık
Keyword(s):  
Thyroid Function ◽  
Thyroid Disease ◽  
Correct Diagnosis ◽  
Thyroid Function Test ◽  
Hashimoto Thyroiditis ◽  
Thyroid Stimulating Hormone ◽  
Thyroid Function Tests ◽  
Test Results ◽  
Function Tests ◽  
Function Test

INTRODUCTION: Thyroid function tests are among the most frequently implemented laboratory tests in primary, and secondary healthcare institutions. The aim of the present study was to investigate the demographic and clinical characteristics and final diagnosis of children referred by primary and secondary healthcare institutions with the suspicion of an abnormality in thyroid function test and/or with the initial diagnosis of specific thyroid disease. METHODS: A total of two hundred eighty-nine pediatric patients, aged between 4 and 18 years admitted to the outpatient clinics of Behçet Uz Children’s Health and Diseases Hospital between January 2018 and January 2020, were included in the study. The patient data were obtained retrospectively from the hospital records. RESULTS: A total of 66% of the patients who were included in the study were female with a median age of 12 years (8.7-14.4), while 64% of them were pubertal; and 78% of the cases were referred by secondary healthcare institutions. The most common reason for referral was isolated elevation of thyroid stimulating hormone (TSH). A total of 56% of the patients were asymptomatic at the time of admission, and thyroid function test results of 75% of them were within normal limits. When evaluated according to their final diagnoses, the children were normal/healthy (64%), diagnosed with Hashimoto thyroiditis (30%), nodular thyroid disease (3%), Graves disease (2%) and isolated increase of TSH was related to obesity in 5 patients (1%). DISCUSSION AND CONCLUSION: It is essential to evaluate children with abnormal thyroid function test results with detailed history and physical examination. Besides, the thyroid function tests should be performed with reliable and sensitive methods in standardized laboratories to reach the correct diagnosis in these children.

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