scholarly journals Study of histomorphological spectrum of ovarian neoplasms: an institutional perspective

2019 ◽  
Vol 6 (5) ◽  
pp. 1563
Author(s):  
Swarnalatha P. ◽  
Rajasekhar Reddy S. ◽  
Chaitanya B.
Keyword(s):  
Ovarian Neoplasms ◽  
Histopathological Examination ◽  
Age Distribution ◽  
Serous Cystadenoma ◽  
Red Cross ◽  
Surface Epithelium ◽  
Malignant Tumours ◽  
Institutional Perspective ◽  
Ovarian Tumours ◽  
Pathological Evaluation

Background: Ovarian tumours account for one of the top five gynaecological malignancies in Indian women. The prime objective of the current study is to document the frequency, age distribution and diverse histomorphological spectrum of ovarian tumours in a peripheral institute in South India catering rural population.Methods: The study comprises of retrospective clinico pathological evaluation of 77 cases of ovarian neoplasms in Indian Red Cross Cancer Hospital, Nellore, India during a 4 year period ( January 2015 to December 2018 ). Non neoplastic ovarian lesions were excluded. Gross and microscopic histopathological examination was done for ovarian neoplasms. These were classified according to the WHO classification of ovarian tumours (2003).Results: Out of 77 cases studied, majority were malignant  tumours (72.72%), followed by benign (23.38%) and borderline tumours (3.9%). Age ranged from 11-80 years. Epithelial tumours were the most common (75.32%), followed by sex cord stromal tumours (12.98%), germ cell tumours (9.09%) and metastatic ovarian tumours (1.3%). Serous cystadenoma was the commonest benign tumour and serous papillary carcinoma was the commonest malignant ovarian tumour.Conclusions: It is concluded from this study that on morphological grounds, tumours originating from surface epithelium are the most common. Higher incidence of malignant tumours supports the metaphor often used for ovarian malignancy “ the silent killer ”.

scholarly journals Clinicopathological analysis of ovarian tumors: a two year retrospective study

2019 ◽  
Vol 8 (8) ◽  
pp. 3015
Author(s):  
Kanika Chandra ◽  
Neetu Arora
Keyword(s):  
Age Distribution ◽  
Germ Cell Tumors ◽  
Ovarian Tumour ◽  
Serous Cystadenoma ◽  
Good Prognosis ◽  
Ovarian Tumors ◽  
Malignant Tumours ◽  
Ovarian Tumours ◽  
Heterogeneous Neoplasm ◽  
Risk Of Malignancy

Background: Ovarian tumours are a heterogeneous neoplasm with a varied clinical, morphological and histological feature. Increasing mortality rate due to ovarian cancers has been reported in recent years. Ovarian tumours in post-menopausal females have high risk of malignancy and it has a very poor outcome. The aim and objective of this study was to determine clinical and histopathological spectrum and the frequency and age distribution of various ovarian tumors.Methods: It is a retrospective observational study of patients with ovarian tumors in the department of obstetrics and gynecology, SGRRI of Medical Health & Sciences and Hospital from January 2016 to December 2017 in a total number of 86 patients. All specimens were sent to pathology department and categorised according to WHO  hispathological classification.Results: Out of 86 cases examined, 64 cases were benign (74.4%), 3 cases were borderline (3.4%) and 19 cases were malignant (22.2%). Majority of the ovarian tumors (73.4%) were seen in the age group of 20 to 50 years. Most commonly encountered benign ovarian tumour was serous cystadenoma (58.1%). Surface epithelial tumors were the commonest tumors (64%) followed by germ cell tumors (29%).Conclusions: A variety of benign and malignant tumours of ovary were reported in this study. Early diagnosis and appropriate treatment of ovarian neoplasms favour the good prognosis. Most common benign tumour encountered in this study was serous cystadenoma.

scholarly journals Spectrum of ovarian tumours- a five year study

2017 ◽  
Vol 7 (2) ◽  
pp. 1180-1183
Author(s):  
Sanjeev Narang ◽  
Anjali Singh ◽  
Shrikant Nema ◽  
Rahul Karode
Keyword(s):  
Histopathological Examination ◽  
Age Distribution ◽  
The Elderly ◽  
Surface Epithelium ◽  
Benign Tumors ◽  
Age Group ◽  
Elderly Age ◽  
Hematoxylin And Eosin ◽  
Hematoxylin And Eosin Stain ◽  
Sex Cord Stromal Tumors

Background: Ovarian tumor is the seventh most common cause of cancer related deaths in female. The aim of this study is to find the, morphological and clinicopathological correlation, gross, histological pattern, and incidence of age distribution of ovarian tumors.Materials and Methods: This retrospective and prospective study was carried out from January 2011 to December 2015. The diagnosis was confirmed by histopathological examination using hematoxylin and eosin stain. Special stains and immunohistochemistry were carried out whenever needed.Results: Out of total 158 cases, 62.65% were benign, 3.79% were borderline, and 33.55% were malignant. Histologically, surface epithelial tumors were the most common (74.06%) followed by germ cell tumours(15.82%) and sex cord–stromal tumors (10.12%).Benign tumors were mostly seen in age group of 20–40 years, borderline 21–40 years, and malignant 50–80 years.Conclusion: Tumors originating from surface epithelium are the most common and their malignant counterparts are more frequent in the elderly age group.

scholarly journals Immature teratoma with a rare finding of choroid plexus

2021 ◽  
Vol 9 (10) ◽  
pp. 3179
Author(s):  
Mehak Kashyap ◽  
Neelam Gupta ◽  
Vikas Dubey ◽  
Nechal Kaur
Keyword(s):  
Young Women ◽  
Histopathological Examination ◽  
Cystic Teratoma ◽  
Ovarian Tumour ◽  
Serous Cystadenoma ◽  
Immature Teratoma ◽  
Rare Tumour ◽  
Rare Finding ◽  
Ovarian Tumours ◽  
Grade 3

Mature cystic teratoma of the ovary is the most common ovarian tumour in young women. Immature teratoma is a very rare tumour, representing only 1% of all ovarian cancers. Paediatric ovarian tumours are rare, with a reported incidence rate of 2.2/100,000 in girls aged 0 to 15 years. In the case report presented here, was 12-year-old suspected to have serous cystadenoma of ovary based on CT scan, which was ultimately diagnosed with immature teratoma grade 3 after histopathological examination was done.

scholarly journals CLINICOPATHOLOGICAL STUDY OF OVARIAN NEOPLASMS – AN INSTITUTIONAL PERSPECTIVE

2021 ◽  
pp. 72-76
Author(s):  
VASUNDARA GARDAS ◽  
PRASANTHI CHERUKURI ◽  
SUMERA SALOMI
Keyword(s):  
Ovarian Neoplasms ◽  
Germ Cell Tumors ◽  
Diagnostic Techniques ◽  
Serous Cystadenoma ◽  
Research Data ◽  
Medical Sciences ◽  
Institutional Perspective ◽  
Epithelial Tumor ◽  
Stromal Tumors ◽  
Sex Cord Stromal Tumors

Objective: The objective of the study was to know the frequency and histomorphological patterns of ovarian neoplasms concerning age. Methods: A 2-year retrospective study was done in the pathology department, GITAM Institute of Medical Sciences and Research. Data were retrieved from laboratory records, H & E slides of ovarian biopsies of diagnosed neoplasms were screened. Results: During the study period, 70 ovarian neoplasms were reported. Ovarian tumors were categorized according to the WHO classification. In this study surface, epithelial tumors were most common at 87.14% followed by germ cell tumors at 11.42% and sex cord-stromal tumors at 1.42%. Serous cystadenoma was the most common benign surface epithelial tumor. Conclusion: Histopathology is the gold standard for diagnosing ovarian neoplasms. Newer diagnostic techniques such as immunohistochemistry and morphometric analysis help decide management and prognosis.

scholarly journals COLLISION TUMOUR IN OVARY;

2019 ◽  
Vol 26 (03) ◽  
Author(s):  
Afra Samad ◽  
Namra Mahmood ◽  
Arbaz Samad
Keyword(s):  
Mature Teratoma ◽  
Mucinous Cystadenoma ◽  
Serous Cystadenoma ◽  
Surface Epithelium ◽  
Granulosa Cell Tumour ◽  
Review Of Literature ◽  
The Third ◽  
Collision Tumour ◽  
Ovarian Tumours ◽  
Sex Cord Stromal Tumor

Most of the ovarian tumours are of surface epithelium and account for 65-75% of tumours.1 Serous cystadenoma constitutes 20% of ovarian tumours. Sex- cord stromal tumour is less common. Fibroma is the most common sex-cord stromal tumor comprising 70%.2 Tumors can present in a combination in ovary like teratoma and mucinous cystadenoma, granulosa cell tumour and mature teratoma and/or mucinous tumors.3 We report a rare case of combined serous cystadenoma and fibroma in a 55 years old female. Review of literature reveal only two such cases. To best of our knowledge this is the third case which is being report.

scholarly journals A report of 26 cases of ovarian lesions as seen in a Tertiary Institution in North-East Nigeria

2014 ◽  
Vol 2 (4) ◽  
Author(s):  
Abdullahi K ◽  
Mohammed U ◽  
Aminu BM ◽  
Dattiji LM
Keyword(s):  
Corpus Luteum ◽  
Age Distribution ◽  
Malignant Tumour ◽  
Serous Cystadenoma ◽  
Malignant Tumours ◽  
Tertiary Institution ◽  
North East ◽  
Neoplastic Lesions ◽  
Age Range ◽  
Corpus Luteum Cyst

varian cancer is a lethal disease. Globally, it claims 125,000 lives per year. Non-neoplastic lesions of the ovary frequently mimic ovarian neoplasms; many occur in the reproductive years and may be associated with infertility. The clinical diagnosis of ovarian cancers is still problematic when compared with that of the cervix owing to the fact that the ovary is less accessible and there has been no universally accepted screening protocol. : To study the pattern and age distribution of non-neoplastic and neoplastic lesions of the ovary in a tertiary institution in North – east Nigeria and compare it with other centers. : It was a retrospective retrieval of oopherectomy specimens seen over a 1 year period with review of their histopathologic characteristics. : A total of 26 oophorectomy specimens were received within the study st st period (1 January 2012 to 31 December 2012). There were 11(42.3%) nonneoplastic conditions and 15(57.7%) neoplastic conditions of which 8 (30.8%) were benign and 7 (26.9%) malignant tumours .The age range of non-neoplastic conditions was 20 to 49 years. Corpus luteum cyst was the most common lesion 4 (15.4%) and a case of ovarian ectopic gestation was observed. Neoplastic lesions were predominantly observed in fourth, third and second decades of life with age range of 17 years to 72 years. Papillary serous Cystadenocarcinoma was the most common malignant tumour, 5(19.2%). : The most common non-neoplastic ovarian lesion was Corpus luteum cyst and the most common benign and malignant ovarian neoplasm was papillary serous Cystadenoma and papillary serous Cystadenocarcima respectively. A further review may be needed in the future to compare epidemiologic trends in the environment

scholarly journals Occurrence and Histopathological Patterns of Ovarian Tumours in a Tertiary Hospital

2017 ◽  
Vol 32 (1) ◽  
pp. 5-9
Author(s):  
Shahnaz Begum ◽  
Ferdousi Begum ◽  
Mohammad Nasimul Islam ◽  
Shahida Haque ◽  
Farhana Israt Jahan
Keyword(s):  
Cystic Teratoma ◽  
Tertiary Hospital ◽  
Serous Cystadenoma ◽  
Malignant Tumours ◽  
Cyst Adenoma ◽  
Benign Ovarian Tumours ◽  
Ovarian Tumours ◽  
Malignant Group ◽  
Serous Cyst Adenoma ◽  
Serous Cyst

Background: Ovarian tumours are common problem in gynaecology and have varied clinical presentation and histopathological appearances. Objectives: This study was undertaken to find out the occurrence and different histopathological types of the tumours originating from the ovaries. Methods: A retrospective study was carried out in the Department of Obstetrics and Gynaecology and Department of Pathology, Sir Salimullah Medical College and Mitford Hospital, Dhaka, between May 2010 and December 2014. Five hundred forty seven (547) cases of ovarian tumours were studied in respect to their histopathological appearance. Results: Out of total gynaecological admission of 5633 patients during the study period, 613 patients admitted with a clinical diagnosis of ovarian tumours: so, the occurrence was 10.9%. Out of 613 patients 547 did histopathology in the department of pathology of our institution. Of the 547 cases, majority were benign (n=379, 69.3%); followed by malignant (n=38, 7%); borderline (n=4, 0.7%); and others (n=126, 23%). Most commonly occurring benign ovarian tumours were serous cystadenoma (115; 30.3%); mature cystic teratoma (76; 20.1%) and mucinous cyst adenoma (66;17.4%). Common malignant tumours were serous cyst adenocarcinoma (21; 55.3%); mucinous cystadenocarcinoma (5; 13.2%) and dysgerminoma(4; 10.5%). Conclusion: Nine out of ten ovarian tumours were nonmalignant. Epithelial tumours were most common among both benign and malignant ovarian tumours. Overall, most common was serous cyst adenoma in benign group and serous cyst adenocarcinoma in malignant group. Bangladesh J Obstet Gynaecol, 2017; Vol. 32(1): 5-9

HISTOPATHOLOGICALANALYSIS OF TUMOURS AND TUMOUR-LIKE LESIONS OF COLON AND RECTUM

2021 ◽  
pp. 9-11
Author(s):  
Durga Nand Jha ◽  
Hari Shankar Mishra ◽  
Ajit Kumar Chaudhary ◽  
Debarshi Jana
Keyword(s):  
Histopathological Examination ◽  
Correct Diagnosis ◽  
Malignant Tumour ◽  
Juvenile Polyp ◽  
Tubular Adenoma ◽  
Malignant Tumours ◽  
Cross Sectional ◽  
Colorectal Biopsies ◽  
Colon And Rectum ◽  
Benign Tumours

Background:Tumours and tumour like lesions of the colon and rectum have overlapping clinical presentation and may be difcult to diagnose on clinical grounds alone. Histopathological examination although helpful to arrive at correct diagnosis, at times may be difcult and may require ancillary tests such as immunohistochemistry. Materials and Methods: A prospective cross sectional study enrolled 125 cases of colorectal biopsies after histopathological conrmation of tumours and tumour like lesions. The specimens were received at the Department of Pathology, DMCH, Laheriasarai, Bihar from December 2019 to November 2020. Results: Out of 125 cases, 32 cases were benign tumours, 36 cases were malignant tumours and 57 cases were tumour like lesions. Most common age range was 51-60 years with mean age of 38 years. Males comprised 76.74% and females 23.26% with ratio of 3:1. Juvenile polyp was the commonest lesion. Among benign tumours, tubular adenoma was the most common (19.2%), adenocarcinoma was most common malignant tumour (25.6%) and juvenile polyp was the most common tumour like lesion (27.2%). Left side was most common side (66.67%) and rectum was the most common site (48.8%). Conclusions: The commonest indications for colorectal biopsies were tumours and tumour like lesions. Juvenile polyp was the most common tumour like lesion, tubular adenoma was the most common benign tumour and adenocarcinoma was the most common malignant tumour. Histopathological examination is a gold standard for conrmation of all tumour and tumours like lesions of colon and rectum.

Histopathological Study of Lesions of the Nasal Cavity, Paranasal Sinuses and Nasopharynx in a Tertiary Care Centre, Visakhapatnam over a Period of 2 Years

2021 ◽  
Vol 8 (33) ◽  
pp. 3054-3059
Author(s):  
Rajendra Prasad Jagannadham ◽  
Lakshmi Latchupatula ◽  
Sravani Ponnada ◽  
Neelima Lalam ◽  
Raghunadhababu Gudipudi ◽  
...  
Keyword(s):  
Nasal Cavity ◽  
Paranasal Sinuses ◽  
Histopathological Examination ◽  
Tertiary Care ◽  
Histopathological Study ◽  
Histopathological Diagnosis ◽  
Malignant Tumours ◽  
Tertiary Care Centre ◽  
Female Ratio ◽  
Male Predominance

BACKGROUND A variety of non - neoplastic and neoplastic conditions involve the nasal cavity, paranasal sinuses and nasopharynx and these are very common lesions encountered in clinical practice. Histopathological examination of these lesions is the gold standard for diagnosis because management and prognosis vary among different lesions. The aim of the present study was to evaluate the histopathological study of the lesions of the nasal cavity, paranasal sinuses and nasopharynx in relation to their incidence, age, gender and site wise distribution and to compare the results with the available data. METHODS A study of 88 cases was conducted for a period of 2 years from August 2017 to July 2019. After fixation, Processing and Haematoxylin and Eosin staining and special stains histopathological diagnosis was made. RESULTS Among 88 total cases, 58 were males and 30 were females. A male predominance was observed with a male to female ratio of 1.93 : 1. They were more common in third, fourth and fifth decade of life. Malignant nasal lesions were seen after fourth decade of life. Nasal lesions were more common in nasal cavity (67.05 %), followed by paranasal sinuses (18.18 %) and nasopharynx (14.75). Out of 88 total cases, 39 (44.32 %) were non - neoplastic, 30 (34.09 %) were benign and 19 (21.59 %) were malignant nasal lesions. CONCLUSIONS Sinonasal lesions and nasopharyngeal lesions can have various differential diagnoses. A complete clinical, radiological and histopathological correlation helps to categorize these sinonasal lesions into various non - neoplastic and neoplastic types. But histopathological examination remains the mainstay of definitive diagnosis. KEYWORDS Nasal Cavity, Paranasal Sinuses, Nasopharynx, Benign Tumours, Malignant Tumours, Histopathological Examination

scholarly journals Pancreatic Neuroendocrine Tumor with Benign Serous Cystadenoma: A Rare Entity

2021 ◽  
Vol 2021 ◽  
pp. 1-5
Author(s):  
Randhir Sagar Yadav ◽  
Ashik Pokharel ◽  
Shumneva Shrestha ◽  
Ashbita Pokharel ◽  
Deepshikha Gaire ◽  
...  
Keyword(s):  
Neuroendocrine Tumor ◽  
Histopathological Examination ◽  
Epigastric Pain ◽  
Pancreatic Neuroendocrine Tumor ◽  
Serous Cystadenoma ◽  
Neuroendocrine Neoplasm ◽  
Management Approach ◽  
Cystic Neoplasms ◽  
Distal Pancreas

Mixed serous-neuroendocrine neoplasm constitutes pancreatic serous cystic neoplasms and pancreatic neuroendocrine tumor, two tumor components with different underlying pathologies. The differentiation of these tumors is important as the management and prognosis depend on the pancreatic neuroendocrine tumor component. We report a case of mixed serous-neuroendocrine neoplasm in a 47-year-old female who presented with epigastric pain abdomen for two years. Imaging studies, tumor markers, thorough systemic evaluation, surgical resection, histopathological examination, and timely follow-up constituted our management approach. A 4 cm × 4 cm mass in the distal pancreas with multiple cysts in the pancreatic parenchyma containing serous fluid on distal pancreatectomy and splenectomy was found. The histopathological examination revealed combined benign serous cystadenoma and neuroendocrine tumor. She did not have any recurrence or metastasis by four years of follow-up.

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