scholarly journals Cognitive-behavioural factors associated with adherence to antiretroviral medication among HIV infected patients in Ibadan, Oyo state

Author(s):  
John I. Akinoye ◽  
Ademola M. Amosu ◽  
Omotayo A. Amodemaja

Background: The initiation of antiretroviral therapy has brought about a huge transformation in HIV care and it has helped in saving millions of lives since its inception. Nevertheless, non-adherence poses a huge challenge to HIV care as this exposes the patients to opportunistic infections and brings about highly resistant viral strains. Therefore, this study assessed the cognitive-behavioural factors associated with the adherence to antiretroviral medication among HIV infected patients in Ibadan, Oyo State, Nigeria.Methods: A descriptive cross sectional study design guided by a behavioural theory was employed. Multistage sampling was employed in this study. Purposive sampling was used to select the hospitals and simple random sampling was used to select the respondents. A 42 item semi-structured questionnaire validated at 0.85 Cronbach alpha was used. Data were analysed using descriptive and inferential statistics at p<0.05.Results: The result showed a mean age of 42.11±11.60 years, while 238 (82.6%) of the respondents were female. The study revealed a positive attitudinal disposition of 54% and a negative perception of 51.5%. Optimal antiretroviral medication adherence among the respondents was 189 (65.6%). Attitude and perception showed a statistical correlation towards antiretroviral medication adherence where p=0.001 and p=0.000 respectively.Conclusions: Attitude and perception are major cognitive-behavioural factors that predicts antiretroviral medication adherence, hence, health promotion intervention that could modify these factors and improve antiretroviral medication adherence is highly recommended.

2015 ◽  
Vol 59 (1) ◽  
pp. 34-41 ◽  
Author(s):  
Juliana Maria Palmeira Canuto ◽  
Virginia Maria Palmeira Canuto ◽  
Matheus Henrique Alves de Lima ◽  
Ana Luiza Costa Silva de Omena ◽  
Thayná Melo de Lima Morais ◽  
...  

Objective To investigate risk factors associated with hypovitaminosis D in adult patients infected with HIV/aids, at a referral hospital in Maceió, Brazil. Subjects and methods This cross-sectional study involved 125 patients evaluated from April to September 2013 by means of interviews, review of medical records, physical examination, and laboratory tests. The data were analyzed using the SPSS® software, version 17.0; the prevalence of hypovitaminosis D and mean levels of vitamin D were determined. The association between hypovitaminosis D and the independent variables was assessed using the Chi-square or the Fisher’s exact tests; mean vitamin D concentrations were analyzed using Kolmogorov-Smirnov, Mann-Whitney, and Kruskal-Wallis tests. The level of significance was set at 5% across tests. Results The prevalence of hypovitaminosis D was 24%, with a significant association with higher household income (p < 0.05). Higher vitamin D levels were associated with female gender (p < 0.001), no use of sunscreen (p < 0.05), and previous opportunistic infections (p < 0.01). Lower values were associated with the use of antiretroviral medication (p < 0.05), overweight and obesity (p < 0.01). Conclusion Lower vitamin D concentrations were significantly associated with well-known risk factors for hypovitaminosis D: use of sunscreen, antiretroviral medication, overweight, and obesity. The prevalence of hypovitaminosis D in this study, considering values > 20 ng/mL or > 30 ng/mL as vitamin D sufficiency, was lower to that of previous studies with HIV-infected patients, a fact that might be related to the low latitude and high intensity of solar radiation of the location of the present study.


2012 ◽  
Vol 51 (3) ◽  
pp. 242-251 ◽  
Author(s):  
Sulachni Chandwani ◽  
Linda J. Koenig ◽  
Anne M. Sill ◽  
Susan Abramowitz ◽  
Latoya C. Conner ◽  
...  

Circulation ◽  
2013 ◽  
Vol 127 (suppl_12) ◽  
Author(s):  
Elizabeth W Holt ◽  
Cara Joyce ◽  
Adriana Dornelles ◽  
Donald E Morisky ◽  
Larry S Webber ◽  
...  

Objectives: We assessed whether socio-demographic, clinical, health care system, psychosocial, and behavioral factors are differentially associated with low antihypertensive medication adherence scores among older men and women. Methods: We conducted a cross-sectional analysis using baseline data from the Cohort Study of Medication Adherence in Older Adults (CoSMO, n=2,194). Low antihypertensive medication adherence was defined as a score <6 on the 8-item Morisky Medication Adherence Scale. Risk factors for low adherence were collected using telephone surveys and administrative databases. Results: The prevalence of low medication adherence scores did not differ by sex [15.0% (193 of 1,283) in women and 13.1% (119 of 911) in men p=0.208]. In sex-specific multivariable models, having issues with medication cost and practicing fewer lifestyle modifications for blood pressure control were associated with low adherence scores among both men and women. Factors associated with low adherence scores in men but not women included reduced sexual functioning (OR = 2.03; 95% CI: 1.31, 3.16 for men and OR = 1.28; 95% CI: 0.90, 1.82 for women), and BMI ≥25 (OR = 3.23; 95% CI: 1.59, 6.59 for men and 1.23; 95% CI: 0.82, 1.85 for women). Factors associated with low adherence scores in women but not men included dissatisfaction with communication with their healthcare provider (OR = 1.75; 95% CI: 1.16, 2.65 for women and OR =1.16 95% CI: 0.57, 2.34 for men) and depressive symptoms (OR = 2.29; 95% CI: 1.55, 3.38 for women and OR = 0.93; 95% CI: 0.48, 1.80 for men). Conclusion: Factors associated with low antihypertensive medication adherence scores differed by sex. Interventions designed to improve adherence in older adults should be tailored to account for the sex of the target population.


2012 ◽  
Vol 50 (2) ◽  
pp. S8-S9
Author(s):  
Errol Lamont Fields ◽  
Laura M. Bogart ◽  
Idia B. Thurston ◽  
Madeleine Wachman ◽  
Elizabeth F. Closson ◽  
...  

2021 ◽  
Vol 8 (3) ◽  
pp. 541-552
Author(s):  
Sphiwe Madiba ◽  
◽  
Ntaoleng Mohlabane

<abstract><sec> <title>Background</title> <p>To address the problem of poor adherence among adolescents with perinatal HIV (PHIV), all clinics in Lesotho offer adolescent-friendly services and psychosocial support to improve their overall health outcomes and adherence. As a result, most adolescents with PHIV attend Teen Clubs as part of the package of youth-friendly HIV services. This study set out to determine whether attending Teen Clubs facilitates treatment adherence among adolescents with PHIV.</p> </sec><sec> <title>Methods</title> <p>In this cross-sectional study, data were collected from 130 adolescents aged 10–19 years who were aware of their HIV status and had attended three or more Teen Club sessions in selected clinics in rural district in Lesotho. Adherence was measured through self-report of last pills missed, based on the 7-days recall of pills taken. Descriptive statistics were used to analyse the data.</p> </sec><sec> <title>Results</title> <p>The median age of adolescents was 15 years, 56% were female, 37.7% were orphans, 41% were being cared for by their grandparents, 6.9% were living with siblings with no adult figure, and two were living on their own. The majority (93%) reported optimal adherence, 92% had not missed a clinic appointment in the past 30 days, and 74.4% knew that if they skipped doses, the viral load would increase and they would get sick. Over half (56%) had been reminded by their caregivers to take their medication and 96% talked to their caregivers regularly about their medication.</p> </sec><sec> <title>Conclusion</title> <p>A supportive environment provided through the Teen Clubs and in the home were the main facilitators for adherence. Strategies to improve adherence among adolescents should consider the importance of the involvement of caregivers in the adolescents' visits to their clinic.</p> </sec></abstract>


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