scholarly journals Medical management of oral submucous fibrosis

Author(s):  
Anjana Agrawal ◽  
Yashaswi Kaushal ◽  
Sudhakar Vaidya ◽  
Kriti Shrivastava

<p class="abstract"><strong>Background:</strong> <span lang="EN-IN">In 1952 Schwartz coined the term “atrophica idiopathica mucosa oris” to describe an oral fibrosing disease he discovered in 5 Indian women from Kenya. Oral submucous fibrosis of oral cavity is a chronic progressive debilitating disease and premalignant condition of oral cavity. The condition is well recognized for its malignant potential and it is particularly associated with aracanut chewing. It is characterized by burning sensation in mouth particularly while eating spicy food and progressive development of inability to open mouth. Worldwide estimate of oral submucous fibrosis indicate that 2.5 million people are affected with a higher incidence in Indian subcontinent. </span></p><p class="abstract"><strong>Methods:</strong> <span lang="EN-IN">This is an observational type of study of 100 patients with oral submucous fibrosis attending ENT OPD.  </span></p><p class="abstract"><strong>Results:</strong> <span lang="EN-IN">We observed that with effective combination of treatment and avoiding predisposing factors and with long time follow-up we got markedly good results. </span></p><p class="abstract"><strong>Conclusions:</strong> <span lang="EN-IN">Although medical management does not completely cure the disease but optimal doses of injection corticosteroid with injection hyaluronidase with avoidance of predisposing factors and improvement of dietary habit with prolong follow up is effective in some extent.</span></p>

Author(s):  
Keshav Kumar ◽  
TabitaJoy Chettiankandy

Oral submucous fibrosis (OSF) is a chronic progressive and irreversible disease affecting the oral, oropharyngeal, and sometimes the esophageal mucous. OSF is a disease that causes changes similar to those of systemic sclerosis (scleroderma) but limited to oral tissues. The disease is seen in those from the Indian subcontinent and from many parts of South-East Asia. It causes significant morbidity (in terms of loss of mouth function as tissues become rigid and mouth opening becomes difficult) and mortality (when transformation into squamous cell carcinoma occurs). The introduction of chewing tobacco containing areca nut into the market has been associated with a sharp increase in the frequency of OSF. Hence based on above findings the present study was planned for Evaluation of Factors Responsible for the Occurrence of Oral Submucous Fibrosis in Patients Referred to Darbhanga Medical College and Hospital. The present study was carried out in the Department of Dentistry, Darbhanga Medical College and Hospital Laheriasarai, Darbhanga Bihar. In the present study 30 cases of the oral submucous fibrosis were enrolled. Oral submucous fibrosis (OSMF) is a chronic insidious disease affecting any part of the oral cavity and sometimes the pharynx. Although, occasionally preceded by or associated with vesicle formation, it is always associated with a juxta-epithelial inflammatory reaction. It is important that preventive efforts be carried out by the concerned authorities and public health professionals in establishing tobacco cessation clinics and tobacco awareness education in such masses (especially the young generation) along with a long standing and a close knit motivation program that enables our future generations to come to avoid the menace of tobacco and its subsequent health effects. Keywords: Oral submucous fibrosis, OSF, oral cavity, Bihar.


2021 ◽  
Vol 14 (3) ◽  
pp. e238718
Author(s):  
Anshul Rai ◽  
Anuj Jain ◽  
Aakash Arora ◽  
Tejas Motiwale

Oral submucous fibrosis (OSF) is a well-documented potentially malignant condition. It affects most commonly the adult patients of India and Indian subcontinent, only few cases affecting children have been reported in the literature. This paper presents three cases of OSF below the age of 12 years and reviews the aetiology, clinical presentation, treatment modalities in children with improved follow-up results. Clinical features like restricted mouth opening, burning sensation and history of betel nut chewing helps in the diagnosis of the patients, which can be confirmed by histopathological examination. Conservative management and oral physiotherapy in children help in improved mouth opening. Counselling the children, their friends and parents also plays a vital role. The present paper highlights that children on a larger scale are using tobacco products and further studies are required with larger sample size.


1985 ◽  
Vol 99 (1) ◽  
pp. 57-60 ◽  
Author(s):  
P. K. Kakar ◽  
R. K. Puri ◽  
V. P. Venkatachalam

AbstractOral Submucous Fibrosis (OSMF) is a disease of unknown etiology. A total of 96 patients with Oral Submucous Fibrosis have received four regimens of treatment–local dexamethasone, local hyaluronidase, local combination of dexamethasone and hyaluronidase, and local placental extract. The patients were followed up for a period varying from 3 months to 2 years. The group of patients receiving hyaluronidase alone showed quicker improvement in symptoms although its combination with dexamethasone gave somewhat better longer-term results. A new regimen for the treatment of submucous fibrosis is recommended.Oral Submucous Fibrosis is a well-known clinical entity, known since the time of Sushurta. In the modern literature, this condition was first reported by Schwartz (1952). Joshi (1953) was the first person to describe this entity in India.Oral Submucous Fibrosis has been defined as an insidious chronic disease of unknown etiology, reported mainly in Indians, and affecting the entire oral cavity. The basic change is a fibro-elastotic transformation of the connective tissue in the lamina propria preceded by vesicle formation. In its later stages the oral mucous membrane becomes stiff and the patient suffers from trismus and resultant difficulty in eating (Pindborg and Sirsat, 1966).The present paper deals with our experience in the management of Oral Submucous Fibrosis over the past 21/2 years.


2021 ◽  
Vol 10 (32) ◽  
pp. 2665-2671
Author(s):  
Falguni Patel ◽  
Shreyas N. Shah ◽  
Christina James

A common oral disease named as oral submucous fibrosis (OSMF) has the tendency to usually affect many areas of the oral cavity as well as involving the area of pharynx. The characteristic feature of oral submucous fibrosis is the fibrosis in submucosal area which involves maximum part of oral cavity leading to advanced lock jaw as a result of rigidity in cheeks, pharynx, lips and upper third part of the oesophageal canal progressing to dysphagia. It has been reported that OSMF occurs mainly in persons who are habituated to chew areca nut or products containing areca nut along with other ingredients. In recent years with the introduction of commercially available Gutka and other areca nut products, the incidence of OSMF is increasing especially in the younger generations. OSMF is irreversible and persists even after cessation of chewing habit and the severity increases along with the duration of habit. In 2007, the categorization of oral submucous fibrosis was done as a premalignant condition by WHO and it has higher chances of malignant transformation. Early diagnosis and application of proper treatment modality is mandatory to reduce morbidity and mortality rate. There are many classification systems that have been proposed in literature for oral submucous fibrosis, among which many are based on clinical features, some of them on functional aspects and others are based on histopathological aspects. Here is an attempt to enlighten the facts and recent updates of clinical, functional, histopathological features as well as pathogenesis and management of oral submucous fibrosis. The complete knowledge of oral submucous fibrosis is a useful to the clinicians as well as academicians and researchers for timely detection and proper management of the disease. KEY WORDS Oral Submucous Fibrosis, Precancerous Lesions, Precancerous Conditions, Sclerosing Stomatitis


2022 ◽  
Vol 19 (1) ◽  
pp. 51-54
Author(s):  
Dwarika Prasad Bajgai ◽  
Bela Agrawal ◽  
Abadhesh Yadav

Introduction: Oral submucous fibrosis is a chronic oral disease characterized by progressive buildup of constricting collagen bands in the cheeks and adjacent structures of the mouth due to chewing of areca nut. This can severely restrict mouth opening and tongue movement causing pain and burning sensation in the mouth. Aims: This study evaluates the efficacy of pentoxifylline in the management of oral submucous fibrosis. Methods: A hospital-based study, conducted in the dental outpatient department of Nepalgunj Medical College from October 2019 to September 2020. Forty-nine patients who were diagnosed histopathologically with oral submucous fibrosis were included. The patients were divided into two groups. In group A, patients were given, 200 mg thrice daily for first 30 days, then dose hiked to 400 mg thrice daily for two more months. Group B patients received treatment with multi-vitamin capsules (B-complex one capsule before sleep daily) for three months. All patients were followed up for six months and were assessed for maximum inter-incisor opening, pain on opening of mouth and burning sensation. Results: There was no statistical difference in mouth opening at baseline and first follow up. The mouth opening was significantly more in group A compared to group B from second follow up which persisted till third follow up (p <0.05). Pain and burning sensation significantly reduced in group A compared to group B from 2nd follow up which persisted till 3rd follow up (p <0.05). Few patients had nausea, dyspepsia and vomiting during treatment in group A which resolved within a few days without the need for cessation of the drug. Conclusion: Pentoxifylline can bring about significant clinical improvements in the symptoms of oral submucous fibrosis like mouth opening, pain and burning sensation, thereby improving the quality of life of the affected individuals.


2020 ◽  
Vol 11 (SPL3) ◽  
pp. 1799-1804
Author(s):  
Aklesha Behera ◽  
Abilasha R ◽  
Pratibha Ramani ◽  
Gheena S ◽  
Hannah R

Oral submucous fibrosis is a chronic, progressive, scarring precancerous condition of the oral cavity seen predominantly in the Indian subcontinent and southeast Asia. OSMF is caused by consumption of areca nuts and tobacco products. Patients suffer from trismus and other related problems. Interincisal mouth opening ranges between 24 to 55 mm in this study, hence making the study groups between I to III. The aim of the study is to find a correlation between age, habits and treatment outcome in OSMF patients. Data was procured from patient records of 86000 patients who visited from between June 2019 and March 2020 and analysis was done. Age is between 21 to 64 years. Male preponderance is seen 92.4% pan chewing is common (35.9%) Interincisal opening is between 24 to 55 mm, making the OSMF grade I and II. OSMF affects people aged 21 to 64 years and the interincisal mouth opening is between 24 to 55 mm, making the grades I and II.


Author(s):  
Amit LNU ◽  
Ashish Soni ◽  
Prateek Agarwal

ABSTRACT Oral submucous fibrosis (OSMF) is an established precancerous condition with increased prevalence in the Indian subcontinent. The treatment of OSMF is a challenging task for a clinician. Different authors have suggested variety of treatment modalities and have claimed success rates; still there is no universally acceptable protocol for the management of OSMF. In our case, transaction of bands was done by contact diode lasers (12 watt) under local anesthesia and it offered good results. Diode lasers offered excellent results and had many advantages over conventional surgical treatment. How to cite this article Soni A, Sharma S, Chitlangia P, Amit, Agarwal P. The Use of Diode Laser in Treatment of Oral Submucous Fibrosis. J Mahatma Gandhi Univ Med Sci Tech 2016;1(2):79-81.


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