scholarly journals Ocular associations in hyperlipidaemia: A rural hospital based study

2022 ◽  
Vol 7 (4) ◽  
pp. 691-694
Author(s):  
Spoorthy S ◽  
Chandana S

The incidence of hypercholesterolemia is ever increasing as the co morbid conditions such as diabetes mellitus, hypertension, stressful life is on a rise. Ocular conditions associated with hypercholesterolemia are issues which are minimally discussed. : This prospective cross-sectional study was conducted from January 2019 to June 2019. Complete eye examination was performed including visual acuity examination, refraction, tear film evaluation, slit lamp examination, measurement of intraocular pressure using rebound tonometer, gonioscopy, direct and indirect ophthalmoscopy Total of 81 patients were examined, out of which males were 55, females were 26. Most common ocular finding was Xanthoma and Xanthelasma in 61(70%) patients. Arcus juvenalis was noted in 12 (14.63%), Lipid keratopathy in 23(29.26%). Other comorbidities associated were Hypertensive Retinopathy, diabetic retinopathy, Pre senile cataract, Primary open angle Glaucoma, Branch retinal vein occlusion which has indirect causal relationship. Along with systemic workup, Hypercholesterolemia also warrants a routine detailed ocular examination even if the patient is asymptomatic. This aids in early diagnosis and management of the co-existing ocular morbidities.

2018 ◽  
Vol 22 (5) ◽  
pp. 376-382 ◽  
Author(s):  
Henrique de Alencar Gomes ◽  
Bruno de Souza Moreira ◽  
Rosana Ferreira Sampaio ◽  
Sheyla Rossana Cavalcanti Furtado ◽  
Sebastião Cronemberger ◽  
...  

Author(s):  
Raheeba Pakeer Muhammed ◽  
Neeta Sidhan ◽  
Beena Thankappan

Introduction: Various haemodynamic factors have been implicated as pathophysiological mechanisms in Primary Open Angle Glaucoma (POAG) other than raised Intraocular Pressure (IOP). However, the exact relationship still remains unclear. Aim: To examine the circadian pattern of Blood Pressure (BP), IOP and Ocular Perfusion Pressure (OPP) with the aim of understanding their relationships in a cohort of patients with POAG. Materials and Methods: A cross-sectional study was conducted in which 44 cases of newly diagnosed, non-hypertensive patients with POAG were enrolled and categorised based on the severity of glaucoma. Recording of BP and IOP were done every 4th hourly during a 24 hour hospital stay. The Mean OPP (MOPP) was calculated as 2/3×Mean Arterial Pressure (MAP)-IOP. Systolic OPP (SOPP) was calculated as Systolic BP-IOP and Diastolic OPP (DOPP) was calculated as Diastolic BP-IOP. The diurnal, nocturnal and 24 hour fluctuations were derived from the difference between the highest and lowest values within each period. Data was analysed using Statistical Package for the Social Sciences (SPSS) version 16.0. Univariate and multivariate regression analysis of the variables with age and severity of POAG were performed Results: Significant positive correlation of the nocturnal fluctuations in MAP (r=0.533), SOPP (r=0.835), DOPP (r =0.768), MOPP (r=0.685) and 24 hour fluctuation in MOPP (r=0.636) were noted with severity of glaucoma on multivariate analysis. No significant correlation of these parameters with age was noted on multivariate analyses. Conclusion: Nocturnal dip in OPP was an important observation among patients with POAG, potentially contributing to its pathophysiology.


2018 ◽  
Vol 7 (01) ◽  
pp. 47-49
Author(s):  
Pandiyaraj Saravanasankar ◽  
Anbazhaghan Amudha ◽  
Srinivasan Muralikrishnan ◽  
Reethysreekumar Sruthi ◽  
Rajan Saranya ◽  
...  

Author(s):  
Syed Zulfequar Ahmad ◽  
Anees Ahmad ◽  
Najam Khalique ◽  
Yasir Alvi

Background: Glaucoma is the leading cause of irreversible blindness worldwide and is second only to cataracts as the most common cause of blindness overall. In the developing world, the prevalence of glaucoma is expected to rise even more dramatically as the population of adults has doubled within a span of few decades. So this study was done with an objective of finding out the prevalence of glaucoma among adults aged 40 years and above in the field practice area of the Department of Community Medicine, Jawaharlal Nehru Medical College, Aligarh Muslim University, Aligarh.Methods: A cross-sectional study was carried out for the duration of one year. A total of 680 persons were interviewed and examined by a trained ophthalmologist for detailed eye examination including visual acuity, refraction and slit-lamp bio-microscopy, intraocular pressure (IOP) by Keeler Pulsair non-contact tonometer confirm by applanation tonometry, gonioscopy, and dilated fundus examination after ruling out the risk of angle closure. Anderson criteria were used to diagnose glaucomatous visual field defect.Results: In our study population, the IOP of the majority of population lied in 11-15 mm Hg with a mean IOP of 13.42±4.09 mmHg. In regard to optic disc examination, a cup to disc ratio of >0.6 was found in 35 eyes. According to the predefined criteria, a total of 31 subjects were diagnosed as glaucoma in either one or both eyes. The overall prevalence of glaucoma was found to be 4.6% (31/680), with the prevalence of primary open angle glaucoma, primary angle closure glaucoma, normotensive glaucoma and secondary glaucoma as 1.3%, 1.2%, 1.2% and 0.9% respectively.Conclusions: The prevalence of glaucoma is quite high in an elder population of Aligarh. This should warrant more intensive activities, focusing not only on early diagnosis and management of glaucoma but also include strengthening preventive ophthalmic care.


1970 ◽  
Vol 10 (1) ◽  
pp. 35-39
Author(s):  
S Bhattarai ◽  
K Sapkota ◽  
SMN Prabhudesai ◽  
JK Shrestha ◽  
AK Sharma

Background: Primary open angle glaucoma (POAG), a chronic, slowly progressive, optic neuropathy, is insidious in onset and painless, until it has caused a significant loss of vision and visual field. Diabetes mellitus and high myopia are the major risk factor of POAG. Objectives: To determine correlation of diabetes mellitus and high myopia in POAG and to estimate the duration of onset of POAG from the diagnosis of diabetes mellitus and high myopia. Method: This retrospective and cross sectional study was conducted in Prabhudesai eye clinic, Pune, India. All the patients diagnosed as POAG from 1st September 2008 to 1st March 2009 AD were included in this study. Association of high myopia with diabetes mellitus was determined by SPSS 13 software. The average duration of onset of POAG after the diagnosis of diabetes mellitus and high myopia was calculated. Results: There were 63.3% (38) male and 36.7% (22) female out of 60 patients of POAG with mean age 54.4±15.4 years. Among them, 27 (45.0%) patients had diabetes mellitus or high myopia. Onset of POAG was found to occur after 11.1±8.3 years of the diagnosis of diabetes and 10.6±3.2 years after the diagnosis of high myopia. Conclusion: The incidence of diabetes mellitus and high myopia was high and significantly associated in primary open angle glaucoma. POAG was detected soon after the onset of diabetes mellitus and high myopia. DOI: http://dx.doi.org/10.3126/hren.v10i1.6005 HREN 2012; 10(1): 35-39


2019 ◽  
Vol 12 (1) ◽  
pp. 22-24
Author(s):  
CB Pun ◽  
S Tuladhar

Objective: The present study was done to find out prevalence of hypertensive retinopathy among patients attending in OPD in GMC. Methods: A hospital based cross-sectional study was performed among 200 hypertensive patients visiting eye OPD from Dec 2016 to Dec 2017. Detailed eye examination including fundus evaluation under mydriasis was done on all subjects and hypertensive retinopathy was graded according to Keith, Wagner and Barker classification by ophthalmologist using 90 dioptre lens. Patient having diabetes and other retinal diseases were excluded from the study. Data analysis was done using spss software. Results: The mean age of the patients was 60.58 ±12.26 standard deviation. In our study 56.5% patients had hypertensive retinopathy. Of which 31% had grade I, 19% had grade II, 6% had grade III and 0.5% had grade IV hypertensive retinopathy. The ratio of hypertensive retinopathy among male and female was 1.7:1. Conclusion: Hypertensive retinopathy is common among hypertensives and males are more prone to retinopathy than females.


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