scholarly journals Oral manifestation of post cancer therapy

2021 ◽  
Vol 9 (2) ◽  
pp. 53-56
Author(s):  
Mutum Sangeeta Devi ◽  
Asif Ahmed
Keyword(s):  
Cancer Therapy ◽  
Turnover Rate ◽  
Oral Microbiota ◽  
Cell Turnover ◽  
Health Issues ◽  
Chewing Tobacco ◽  
Oral Manifestation ◽  
Patients With Cancer ◽  
Chemotherapy Patients ◽  
Tobacco Usage

Oral cancer has become serious health issues. It is owing to a variety of factors including poor hygiene, tobacco usage, chewing tobacco, smoking, and others. Along with surgery and chemotherapy, the most common treatments include radiation therapy and chemotherapy. Patients with cancer may experience oral toxic effects as a result of antineoplastic therapy such as radiotherapy and chemotherapy. A variety of factors influence radiation, including the oral mucosa's fast cell turnover rate, the richness and complexity of the oral microbiota, and soft tissue stress during normal mouth function. The present literature review is for awareness regarding the main oral manifestation secondary to post cancer therapy.

scholarly journals A Copay Foundation Assistance Support Program for Patients Receiving Intravenous Cancer Therapy

2011 ◽  
Vol 7 (2) ◽  
pp. 100-102 ◽  
Author(s):  
Swapnil P. Rajurkar ◽  
Cary A. Presant ◽  
Linda D. Bosserman ◽  
Wendy J. McNatt
Keyword(s):  
Cancer Therapy ◽  
Financial Assistance ◽  
Financial Hardship ◽  
Support Program ◽  
Chemotherapy Drugs ◽  
Patients With Cancer ◽  
Appropriate Treatment

Copay for chemotherapy drugs is a financial hardship for many patients with cancer. The authors have developed a support program to work closely with copay assistance foundations to secure financial assistance for appropriate treatment.

The Role of Psilocybin-Assisted Psychotherapy to Support Patients With Cancer: A Critical Scoping Review of the Research

2021 ◽  
pp. 089801012110390
Author(s):  
Rebecca H. Lehto ◽  
Megan Miller ◽  
Jessica Sender
Keyword(s):  
Mental Health ◽  
Health Issues ◽  
Mushroom Species ◽  
Patients With Cancer ◽  
Existential Suffering ◽  
Vulnerable Patients ◽  
Scoping Literature Review ◽  
Life Threatening ◽  
Self Transcendence

Treatments for addressing psychiatric mental health issues in vulnerable patients with cancer are established. Yet, many patients persist with unrelenting psychological difficulties despite intervention. There is growing interest in the role of psilocybin-assisted psychotherapy for managing treatment-resistant mental health challenges in patients with cancer. Psilocybin is a naturally occurring compound derived from certain mushroom species that can induce entheogenic experiences or an altered state of consciousness. Reed's Self-Transcendence Theory provides a holistic lens to examine existential concerns and mental health in individuals who perceive their illness as potentially life threatening, such as those with cancer. This scoping literature review used Arksey and O’Malley's template to evaluate research examining psilocybin-assisted psychotherapy for patients with cancer. Eight articles met inclusion/exclusion criteria (four quantitative, two mixed methods, and two qualitative). Review findings indicated that the majority of patient experiences were positive, centering on themes of death acceptance, reflection, and broadened spirituality. Although psilocybin-assisted psychotherapy is in early stages of clinical testing, it thus shows promise for carefully screened patients with cancer who have persistent existential suffering. It will be critical for investigators to tailor this emerging intervention to select patients and for clinicians to be engaged in assessment of outcomes and efficacy.

Patients— and Physiotherapists— Belief in and Use of Acupuncture for Cancer-Related Symptoms

2017 ◽  
Vol 35 (4) ◽  
pp. 251-258 ◽  
Author(s):  
Anna Enblom
Keyword(s):  
Treatment Outcome ◽  
Cancer Therapy ◽  
Cancer Pain ◽  
Therapeutic Relationships ◽  
Vasomotor Symptoms ◽  
Treatment Expectations ◽  
Patients With Cancer ◽  
Radiotherapy Treatment

Background It is important to investigate attitudes to acupuncture, because therapists’ and patients’ expectations may affect the treatment outcome. Aim To explore the use of and belief in acupuncture among oncological physiotherapists and to explore patients’ interest in receiving acupuncture during cancer therapy and their belief in its effectiveness. Methods 522 patients (80% female, mean age 67 years) reported on their interest in receiving acupuncture for nausea during radiotherapy treatment; a subgroup (n=198) additionally disclosed their belief in the effectiveness of acupuncture. 117 Swedish oncological physiotherapists (96% female, mean age 48 years) answered a questionnaire regarding their use of and belief in acupuncture. Results Of the patients initiating cancer therapy, 359 (69%) were interested in receiving acupuncture. The patients believed acupuncture to be effective for pain (79%), nausea (79%) and vasomotor symptoms (48%). Of the 117 physiotherapists, 66 (56%) practised acupuncture. Physiotherapists generally believed in the effectiveness of acupuncture. For pain, 89% believed that acupuncture was effective and 42% of them practised it. Similar responses were noted for chemotherapy-induced nausea (86% and 38%, respectively) and vasomotor symptoms (80% and 28%, respectively). Younger physiotherapists and patients were more likely to believe in the effectiveness of acupuncture compared with older ones. Conclusions More than two thirds of patients with cancer were interested in receiving acupuncture during therapy. Patients and oncological physiotherapists believed that acupuncture was effective for cancer pain, nausea and vasomotor symptoms. Further studies of acupuncture for cancer-related symptoms and of the effect of patients’ and clinicians’ therapeutic relationships, including treatment expectations, would be welcome.

scholarly journals Online Communities as Sources of Peer Support for People Living With Cancer: A Commentary

2018 ◽  
Vol 14 (12) ◽  
pp. 725-730 ◽  
Author(s):  
Tanya Gupta ◽  
Lidia Schapira
Keyword(s):  
Online Communities ◽  
Health Care Professionals ◽  
Information Exchange ◽  
Common Interest ◽  
Health Issues ◽  
Patients With Cancer ◽  
Philanthropic Organizations ◽  
Sources Of Support ◽  
Living With Cancer ◽  
Start Ups

Online communities are virtual spaces dedicated to hosting conversations between individuals with a common interest. Information can be shared and obtained incrementally, as users can periodically post both questions and responses to other users’ questions. Although online communities have been used frequently by patients for a myriad of health issues, much remains to be learned about these resources. In this commentary, we explore the emerging role of online communities as forums for information exchange and sources of support for patients with cancer and caregivers. We discuss selected examples of online communities launched by research institutions, advocacy groups, philanthropic organizations, start-ups, and novel enterprises featuring collaborations between industry, health care professionals, and advocates. We explore the risks and benefits of online communities as perceived by oncology clinicians and provide practical recommendations for improving communication between clinicians and patients about the use of online resources.

scholarly journals Low Vitamin C Status in Patients with Cancer Is Associated with Patient and Tumor Characteristics

Nutrients ◽  
2020 ◽  
Vol 12 (8) ◽  
pp. 2338 ◽  
Author(s):  
Rebecca White ◽  
Maria Nonis ◽  
John F. Pearson ◽  
Eleanor Burgess ◽  
Helen R. Morrin ◽  
...  
Keyword(s):  
Cancer Therapy ◽  
Vitamin C ◽  
Human Health ◽  
Cancer Patients ◽  
Vital Role ◽  
Tumor Characteristics ◽  
Patients With Cancer ◽  
Plasma Ascorbate ◽  
Number Of Patients ◽  
Low Levels

Vitamin C (ascorbate) acts as an antioxidant and enzyme cofactor, and plays a vital role in human health. Vitamin C status can be affected by illness, with low levels being associated with disease due to accelerated turnover. However, robust data on the ascorbate status of patients with cancer are sparse. This study aimed to accurately measure ascorbate concentrations in plasma from patients with cancer, and determine associations with patient or tumor characteristics. We recruited 150 fasting patients with cancer (of 199 total recruited) from two cohorts, either prior to cancer surgery or during cancer chemo- or immunotherapy. A significant number of patients with cancer had inadequate plasma ascorbate concentrations. Low plasma status was more prevalent in patients undergoing cancer therapy. Ascorbate status was higher in women than in men, and exercising patients had higher levels than sedentary patients. Our study may prompt increased vigilance of ascorbate status in cancer patients.

scholarly journals The Safety of Acupuncture in Patients with Cancer Therapy–Related Thrombocytopenia

2015 ◽  
Vol 27 (3) ◽  
pp. 224-229 ◽  
Author(s):  
Paul A. Cybularz ◽  
Karen Brothers ◽  
Gurneet M. Singh ◽  
Jennifer L. Feingold ◽  
Mark E. Lewis ◽  
...  
Keyword(s):  
Cancer Therapy ◽  
Patients With Cancer

Modafinil for fatigue associated with docetaxel-based chemotherapy: A randomized controlled trial.

2012 ◽  
Vol 30 (5_suppl) ◽  
pp. 211-211
Author(s):  
Elizabeth J. Hovey ◽  
Paul L. De Souza ◽  
Gavin M. Marx ◽  
Phillip Parente ◽  
Tal Rapke ◽  
...  
Keyword(s):  
Primary Endpoint ◽  
Controlled Trial ◽  
Area Under The Curve ◽  
Study Medication ◽  
Double Blind ◽  
Patients With Cancer ◽  
Parallel Group ◽  
Grade 3 ◽  
Chemotherapy Patients ◽  
Md Anderson

211 Background: Chemotherapy-induced fatigue is a common complaint for patients with cancer. We investigated whether modafinil, a psychostimulant, could reduce fatigue in patients on chemotherapy. Methods: A multicenter, randomized, double-blind, placebo-controlled, parallel group study was conducted in patients with metastatic prostate or breast cancer suffering significant chemotherapy-related fatigue whilst undergoing docetaxel-based chemotherapy. Patients were enrolled at the start of their 3rdor subsequent cycles of docetaxel which was continued for up to four further cycles (defined here as ‘treatment periods’). Patients were randomized 2:1 to receive modafinil 200mg daily or placebo for 15 days during each treatment period. Fatigue was evaluated by the MD Anderson Symptom Inventory (MDASI). The primary endpoint was MDASI area under the curve (AUC) during the first 7 days of study medication for the first two treatment periods (possible range 0-70). Other validated tools were used to record disturbances in sleep, mood and functional status. Results: Eighty-three patients (65 with prostate cancer) were randomized and received at least one dose of study medication. The number of grade 3 or 4 adverse events (AEs) was 16/55 (29.1%) in the modafinil group and 5/28 (17.9%) in the placebo group. The toxicity profile was largely consistent with docetaxel-based chemotherapy and with previously reported AEs associated with modafinil use in the community; 11 AEs were possibly related to docetaxel; 1 to modafinil and 9 to neither treatment. Conclusions: Managing chemotherapy-related fatigue remains a major challenge. Despite not reaching the primary endpoint, there was a consistent trend towards improvement of chemotherapy-related fatigue in the modafinil arm. Further studies are needed to better understand the clinical implications of these findings. Funding sanofi-aventis; Study ID NCT00917748 . [Table: see text]

An emerging epidemic: cancer and heart failure

2016 ◽  
Vol 131 (2) ◽  
pp. 113-121 ◽  
Author(s):  
Paaladinesh Thavendiranathan ◽  
Mark T. Nolan
Keyword(s):  
Heart Failure ◽  
Cancer Therapy ◽  
Clinical Decision Making ◽  
Prediction Models ◽  
Clinical Decision ◽  
Prevention Strategies ◽  
Patients With Cancer ◽  
Increased Risk ◽  
Adult Cancer Survivors ◽  
Shared Risk

Heart disease and cancer are the two leading causes of mortality globally. Cardiovascular complications of cancer therapy significantly contribute to the global burden of cardiovascular disease. Heart failure (HF) in particular is a relatively common and life-threatening complication. The increased risk is driven by the shared risk factors for cancer and HF, the direct impact of cancer therapy on the heart, an existing care gap in the cardiac care of patients with cancer and the increasing population of adult cancer survivors. The clear relationship between cancer treatment initiation and the potential for myocardial injury makes this population attractive for prevention strategies, targeted cardiovascular monitoring and treatment. However, there is currently no consensus on the optimal strategy for managing this at-risk population. Uniform treatment using cardioprotective medications may reduce the incidence of HF, but would impose frequently unnecessary and burdensome side effects. Ideally we could use validated risk-prediction models to target HF-preventive strategies, but currently no such models exist. In the present review, we focus on evidence and rationales for contemporary clinical decision-making in this novel field and discuss issues, including the burden of HF in patients with cancer, the reasons for the elevated risk and potential prevention strategies.

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