scholarly journals Risk and Vulnerability Assessment: A Case Study of Pakistan

2021 ◽  
Author(s):  
Arshad Ali
Keyword(s):  
High Risk ◽  
Plain Concrete ◽  
Flood Frequency ◽  
Risk Map ◽  
Building Stock ◽  
Time Period ◽  
Risk Zones ◽  
Negative Impacts

Climate change has put the planet earth on high risk due to flash, riverine flooding and droughts. Unprecedented frequent flooding, hurricanes, droughts and heavy snowfalls can be witnessed in the past few decades. Now no country can declare itself safe from the negative impacts of changing climate. To reduce the risk of potential damages, vulnerability and risk assessment can give a clear picture of a particular region regarding a specific hazard. It will help the administration to address those areas which are highly at risk due to a certain hazard so as to minimize collateral damages in future. In Khyber Pukhtoonkhwa, Nowshera was one of the most affected districts. It has destroyed building stock, livestock and crops in most parts of the district. To minimize these losses in future, this research has been carried out to assess the current condition of building stock in Nowshera Cantt and Nowshera City area. This research explores in detail the building stock vulnerability and associated risk. This research has found that the flood reoccurrence time period is 7 years for zone 1and 7. While other zones 2, 3,4,5,6,8 and 9 have 81 years of reoccurrence time period. Based on the physical vulnerability, this research found that there are five types of buildings in the study area. Vulnerability of Type 1 to 5 are varying  from strong to weak according to its  structures having RCC roof, strong walls, plain concrete / tiles floor. Flood risk map has been produced on the basis of flood frequency and typology of high frequency structures in that particular area. The research explicitly shows different areas in risk map according to the level of risk i.e. from low to high risk zones.  This research has found that binding material is the major factor in structural damages in the study area.

scholarly journals Freeze-thaw Damage Dependence on Wind-driven Rain of Outdoor Exposed Concrete – A Case Study

2019 ◽  
Vol 61 (2) ◽  
pp. 91-106
Author(s):  
Toni A. Pakkala ◽  
Jukka Lahdensivu ◽  
Petteri Huuhka
Keyword(s):  
Precast Concrete ◽  
Lower Amount ◽  
Climate Data ◽  
Concrete Element ◽  
Building Stock ◽  
Freeze Thaw ◽  
Deterioration Rate ◽  
Time Period ◽  
Protective Methods

Abstract It has been shown in previous studies that the existing precast concrete element building stock in Finland has quality issues, especially with freeze-thaw durability and reinforcement corrosion. In addition, it has been presented that deterioration rate is the fastest in coastal area and decreases towards north which has been supposed to be a reason of lower amount of wind-driven rain (WDR). The aim of this study was to examine the connection between the amount of WDR on structures and the freeze-thaw damage more comprehensively. Condition investigation reports of 472 precast concrete element buildings were reanalysed to study the relation and the results were compared to climate data of the same time period to study the correlation between condition investigation observations and the amount of WDR. In addition, the observations made in a condition investigations and their relation to climate load at the same building were studied as a case study. The results show that there is a significant connection between the WDR related climate load and the freeze-thaw damage occurrence. The results can be used to plan protective methods and be a base for service life estimations.

Apoptosis and proliferation ofperipheral blood T-cells as alternative processes in pathogenesis of diabetes mellitus type 1

2019 ◽  
Vol 1 (4) ◽  
pp. 16-20 ◽  
Author(s):  
A. V. Lugovaya ◽  
N. M. Kalinina ◽  
V. Ph. Mitreikin ◽  
Yu. P. Kovaltchuk ◽  
A. V. Artyomova ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
T Cells ◽  
High Risk ◽  
Peripheral Blood ◽  
Cellular Response ◽  
Proliferative Potential ◽  
Autoreactive T Cells ◽  
Alternative Processes

Apoptosis, along with proliferation, is a form of lymphocyte response to activating stimuli. In the early stages of cell differentiation, the apoptotic response prevails and it results to the formation of tolerance to inductor antigen. Mature lymphocytes proliferate in response to stimulation and it means the initial stage in the development of the immune response. Since in this case apoptosis and proliferation acts as alternative processes, their ratio can serve as a measure of the effectiveness of the cellular response to activating signals. The resistance of autoreactive T-cells to apoptosis is the main key point in the development of type 1 diabetes mellitus (T1DM). Autoreactive T-cells migrates from the bloodstream to the islet tissue of the pancreas and take an active part in b cells destruction. The resistance of autoreactive effector T-cells to apoptosis may suggest their high proliferative potential. Therefore, the comparative evaluation of apoptosis and proliferation of peripheral blood lymphocytes can give a more complete picture of their functional state and thus will help to reveal the causes of ineffective peripheral blood T-ceiis apoptosis in patients with T1DM and will help to understand more deeply the pathogenesis of the disease. in this article, the features of proliferative response of peripheral blood T-cells in patients with T1DM and in individuals with high risk of developing T1DM have been studied. Apoptosis of T-cell subpopulations has been investigated. The correlation between the apoptotic markers and the intensity of spontaneous and activation- induced in vitro T-cells proliferation of was revealed. it was determined, that autoreactive peripheral blood T-cells were resistant to apoptosis and demonstrated the increased proliferative potential in patients with T1DM and in individuals with high risk of developing T1DM.

1544-P: High Risk of Adverse Drug Reaction (ADR) in Older Adults with Type 1 Diabetes (T1D)

Diabetes ◽  
2019 ◽  
Vol 68 (Supplement 1) ◽  
pp. 1544-P ◽  
Author(s):  
ELENA TOSCHI ◽  
CHRISTINE SLYNE ◽  
ASTRID ATAKOV-CASTILLO ◽  
KAYLA SIFRE ◽  
ALYSSA B. DUFOUR ◽  
...  
Keyword(s):  
Older Adults ◽  
Adverse Drug Reaction ◽  
Type 1 Diabetes ◽  
Drug Reaction ◽  
High Risk

344-OR: Slowed Metabolic Decline after Oral Insulin (OI) in Relatives at High Risk for Type 1 Diabetes (T1D)

Diabetes ◽  
2020 ◽  
Vol 69 (Supplement 1) ◽  
pp. 344-OR
Author(s):  
JAY SOSENKO ◽  
JERRY P. PALMER ◽  
MICHAEL J. HALLER ◽  
JAY S. SKYLER ◽  
ALBERTO PUGLIESE ◽  
...  
Keyword(s):  
Type 1 Diabetes ◽  
High Risk ◽  
Oral Insulin

Ayurvedic management of Leukoplakia - A Case Study

2017 ◽  
Vol 2 (3) ◽  
Author(s):  
Makadia Krishna ◽  
Ronakgiri V. Gosai ◽  
Virpariya Jignesh ◽  
Chabhadiya Nilesh ◽  
Katrodiya Jayesh ◽  
...  
Keyword(s):  
High Risk ◽  
Oral Mucosa ◽  
Male Patient ◽  
Soft Palate ◽  
Burning Sensation ◽  
Oral Leukoplakia ◽  
Premalignant Lesion ◽  
Allopathic Medicine ◽  
Floor Of The Mouth

Oral leukoplakia (OL) is a premalignant lesion described as “a predominant white lesion of the oral mucosa which cannot be defined as any other known lesion”. OL located on the floor of the mouth, soft palate and tongue are considered as high-risk lesions, while, in other areas, they may be considered as of low malignancy risk. A Forty five years old male patient had complaints of white lesion on left lat. Surface of tongue, along with burning sensation since 4-5 months. He was diagnosed with Leukoplakia and he had taken allopathic medicine for 4 to 5 times, but it was inversely relapsed, so he was treated with Pratisarana of Bibhitaka Churna and Rasayana Churna, Yastimadhu Ghanavati as lozenges along with Rasayana tablets orally for a period of 6 months. After 6 month therapy, white lesion became disappear and no burning sensation. Thus this patient was successfully treated with above therapy with no recurrence or any complications till date.

Catching an Atom Spy: MI5 and the Investigation of Klaus Fuchs

2010 ◽  
pp. 554-567
Author(s):  
Timothy Gibbs
Keyword(s):  
Cold War ◽  
High Risk ◽  
Klaus Fuchs ◽  
Key Issues ◽  
Successful Approach ◽  
Anglo American ◽  
Atomic Espionage ◽  
Signals Intelligence

This article focuses on M15 organization and Klaus Fuchs, a German-born physicist and Soviet “Atom Spy” who was arrested in 1950 and served fourteen years for offences related to atomic espionage. It examines how Fuchs was identified as an “Atom Spy” in 1949 and describes the MI5's investigation, which ended in the early 1950 with the successful arrest, prosecution, and imprisonment of this highly significant Cold War figure. Key issues discussed in this article include the difficulties encountered by MI5 and the budding British atomic program in the sphere of security. It also discusses the role of Signals intelligence (SIGINT) in the investigation of Fuchs, and the high-risk but ultimately successful approach taken by MI5's key interrogator, William Skardon. This case study highlights both the unparalleled level of international intelligence cooperation between the British agencies and their American counterparts, which made the resolution of this case possible, and some of the frailties in the Anglo-American alliance that were brought to the fore by the exposure of Fuchs as an Atom Spy.

scholarly journals The reasons women choose and stay in a geology major: a qualitative multi-case analysis

2021 ◽  
Vol 3 (1) ◽  
Author(s):  
Ron E. Gray ◽  
Alexis T. Riche ◽  
Isabel J. Shinnick-Gordon ◽  
James C. Sample
Keyword(s):  
Role Models ◽  
Critical Incident ◽  
Earth Science ◽  
Time Period ◽  
The Usa ◽  
Data Source ◽  
Introductory Classes ◽  
Iterative Coding ◽  
As Relationship

AbstractDespite earning half of all science and engineering undergraduate degrees between 2007 and 2016 in the USA, women were awarded only 39% of earth science degrees in the same time period. In order to better understand why women are both choosing and staying in geology programs, we conducted a multi-case study of nine current female undergraduate geology majors at a large public university in the USA within a department that is at gender parity among its undergraduate majors. The main data source was audio-recorded critical incident interviews of each participant. Data from the interviews were analyzed through an iterative coding process using codes adapted from previous studies that focused on factors both internal and external to the department. The students said that personal interests, influence by others outside of the department, and introductory classes attracted them to the geology program, but once declared, departmental factors such as relationship with faculty caused them to stay. We also found an emphasis on female role models, especially those teaching introductory courses. We believe this study offers important insights into the ways in which factors leading to recruitment and retention play out in the lived experiences of female geology majors.

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