scholarly journals Use of Polyguanidine-Derivatives-Based Biocides for Microbial Growth Inhibition and for the Development of a Novel Polyethylene-Based Composite Material Resistant to the Formation of Multispecies Microbial Biofilms

2022 ◽  
Author(s):  
Marina Zhurina ◽  
Andrei Gannesen ◽  
Sergey Martyanov ◽  
Anna Kallistova ◽  
Victor Gerasin ◽  
...  
Keyword(s):  
Biofilm Formation ◽  
Microbial Growth ◽  
Guanidine Hydrochloride ◽  
Tropical Soil ◽  
Biocidal Activity ◽  
Microbial Biofilms ◽  
Diallyldimethylammonium Chloride ◽  
Polyhexamethylene Guanidine ◽  
Microbial Growth Inhibition ◽  
Surrounding Soil

This study aimed to investigate the dependence of the biocidal activity of polyguanidine (co)polymers on their structure during the formation of biofilms by active PE-degrading cultures of model microorganisms. The Bc-2 copolymer of methacryloyl guanidine hydrochloride (MGHC) and diallyldimethylammonium chloride (DADMAC), which suppressed both the formation of biofilms and the growth of planktonic cultures, exhibited the highest activity. When PE was exposed in tropical soil, the composition of the microbial community on the PE surface differed significantly from that of the community in the surrounding soil. In particular, the proportion of Actinobacteria increased from 7% to 29%, while the proportion of Bacteroidetes decreased from 38% to 8%. Keywords: biofilms, polyhexamethylene guanidine salts, dynamics of biofilm formation, antibiofilm effect, composite materials

Influence of mixed aqueous solutions of polyhexamethylene guanidine hydrochloride and OP-10 on vegetable crop seeds

2018 ◽  
Vol 11 (2) ◽  
pp. 164-172
Author(s):  
О.A. Yessimova ◽  
◽  
А.О. Adilbekova ◽  
M.Zh. Kerimkulova ◽  
G.D. Isenova ◽  
...  
Keyword(s):  
Aqueous Solutions ◽  
Guanidine Hydrochloride ◽  
Vegetable Crop ◽  
Polyhexamethylene Guanidine

scholarly journals Silver-Derived Antimicrobial Coatings for the Prevention of Microbial Biofilms in Metal Pipes

2021 ◽  
Vol 232 (8) ◽  
Author(s):  
M. Vela-Cano ◽  
C. Garcia-Fontana ◽  
F. Osorio ◽  
A. González-Martinez ◽  
J. González-López
Keyword(s):  
Biofilm Formation ◽  
Antimicrobial Properties ◽  
Pilot Scale ◽  
Biological Factors ◽  
Antimicrobial Coatings ◽  
Microbial Biofilms ◽  
Physical Chemical ◽  
Silver Zeolite ◽  
Metal Pipes ◽  
Pipeline Corrosion

AbstractBiodeterioration is one of the most important processes in metal pipeline corrosion, and it can be due to physical, chemical, and biological factors. Coatings rich in silver have been used to inhibit this undesirable phenomenon. In this study, the antimicrobial properties of several silver-containing products used as a coating in pipelines were determined on a pilot scale in order to evaluate the ability of silver to inhibit biofilm formation. The results showed that the coating with silver zeolite at a concentration of 2000 mg L–1 inhibited the formation of a microbial biofilm and prevented the biodeterioration process. Therefore, from our study, it can be concluded that silver zeolite shows greater protection capacity than other silver preparations and presents advantages in relation to other silver coatings that are currently available

scholarly journals Mediterranean herb extracts inhibit microbial growth of representative oral microorganisms and biofilm formation of Streptococcus mutans

PLoS ONE ◽  
2018 ◽  
Vol 13 (12) ◽  
pp. e0207574 ◽  
Author(s):  
Joachim Hickl ◽  
Aikaterini Argyropoulou ◽  
Maria Eleni Sakavitsi ◽  
Maria Halabalaki ◽  
Ali Al-Ahmad ◽  
...  
Keyword(s):  
Streptococcus Mutans ◽  
Biofilm Formation ◽  
Microbial Growth ◽  
Herb Extracts ◽  
Oral Microorganisms

scholarly journals INFLUENCE OF POLIGUANIDINE ON THE SELF-ORGANIZATION PROCESS IN CYSTEINE-SILVER SOLUTION

2021 ◽  
pp. 69-79
Author(s):  
Анна Нориковна Адамян ◽  
Алена Константиновна Кучурова ◽  
Александра Ивановна Иванова ◽  
Максим Дмитриевич Малышев ◽  
Виктор Анатольевич Герасин ◽  
...  
Keyword(s):  
Guanidine Hydrochloride ◽  
Self Organization ◽  
Silver Acetate ◽  
High Antimicrobial Activity ◽  
Antibacterial Studies ◽  
Polyhexamethylene Guanidine ◽  
Silver Solution ◽  
Organization Process ◽  
Spatial Grid ◽  
Test Cultures

Выполнены реологические, структурные и антибактериальные исследования гидрогелей, получаемых на основе L-цистеина, ацетата серебра и полигексаметиленгуанидин гидрохлорида (ПГМГ-ГХ). Установлено, что водные растворы на основе L-цистеина и ацетата серебра хорошо смешиваются с водным раствором ПГМГ-ГХ, образуя прозрачные гидрогели. Предложена модель строения пространственной сетки геля. Показана высокая антимикробная активность гидрогеля по отношению к тест-культурам патогенных и условно-патогенных микроорганизмов. Rheological, structural, and antibacterial studies of hydrogels based on L-cysteine, silver acetate, and polyhexamethylene guanidine hydrochloride (PHMG-GC) have been carried out. It was found that aqueous solutions based on L-cysteine and silver acetate mix well with an aqueous solution of PHMG-GC, forming transparent hydrogels. A model of the structure of the spatial grid of the gel is proposed. High antimicrobial activity of the hydrogel was shown in relation to test cultures of pathogenic and opportunistic microorganisms.

scholarly journals Direct-from-specimen microbial growth inhibition spectrums under antibiotic exposure and comparison to conventional antimicrobial susceptibility testing

2021 ◽  
Author(s):  
Jade Chen ◽  
Su Su Soe San ◽  
Amelia Kung ◽  
Michael Tomasek ◽  
Dakai Liu ◽  
...  
Keyword(s):  
New York ◽  
Growth Inhibition ◽  
Antimicrobial Susceptibility ◽  
Microbial Growth ◽  
Susceptibility Testing ◽  
Antimicrobial Susceptibility Testing ◽  
Patient Treatment ◽  
Broth Microdilution Method ◽  
Microbial Growth Inhibition ◽  
Urine Specimens

AbstractIncreasing global travel and changes in the environment may increase the frequency of contact with a natural host carrying an infection, and therefore increase our chances of encountering microorganisms previously unknown to humans. During an emergency (man-made, natural disaster, or pandemic), the etiology of infection might be unknown at the time of patient treatment. The existing local or global Antimicrobial Stewardship Programs might not be fully prepared for emerging/re-emerging infectious disease outbreaks, especially if they are caused by an unknown organism, engineered bioterrorist attack, or rapidly evolving superbug. We demonstrate an antimicrobial efficacy profiling method that can be performed in hours directly from clinical urine specimens. The antimicrobial potency is determined by the microbial growth inhibition and compared to conventional antimicrobial susceptibility testing (AST) results. The oligonucleotide probe pairs on the sensor were designed to target gram-negative bacteria, specifically Enterobacterales and Pseudomonas aeruginosa. A total of 10 remnant clinical specimens from the CLIA labs of New York-Presbyterian Queens were tested, resulting in 100% categorical agreement with reference AST methods (Vitek and broth microdilution method). The combined categorical susceptibility reporting of 12 contrived urine specimens was 100% for ciprofloxacin, gentamicin, and meropenem over a range of microbial loads from 105 to 108 CFU/mL.

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