scholarly journals Silver-Derived Antimicrobial Coatings for the Prevention of Microbial Biofilms in Metal Pipes

2021 ◽  
Vol 232 (8) ◽  
Author(s):  
M. Vela-Cano ◽  
C. Garcia-Fontana ◽  
F. Osorio ◽  
A. González-Martinez ◽  
J. González-López
Keyword(s):  
Biofilm Formation ◽  
Antimicrobial Properties ◽  
Pilot Scale ◽  
Biological Factors ◽  
Antimicrobial Coatings ◽  
Microbial Biofilms ◽  
Physical Chemical ◽  
Silver Zeolite ◽  
Metal Pipes ◽  
Pipeline Corrosion

AbstractBiodeterioration is one of the most important processes in metal pipeline corrosion, and it can be due to physical, chemical, and biological factors. Coatings rich in silver have been used to inhibit this undesirable phenomenon. In this study, the antimicrobial properties of several silver-containing products used as a coating in pipelines were determined on a pilot scale in order to evaluate the ability of silver to inhibit biofilm formation. The results showed that the coating with silver zeolite at a concentration of 2000 mg L–1 inhibited the formation of a microbial biofilm and prevented the biodeterioration process. Therefore, from our study, it can be concluded that silver zeolite shows greater protection capacity than other silver preparations and presents advantages in relation to other silver coatings that are currently available

scholarly journals Role of Pirin, an Oxidative Stress Sensor Protein, in Epithelial Carcinogenesis

Biology ◽  
2021 ◽  
Vol 10 (2) ◽  
pp. 116
Author(s):  
Francisco Perez-Dominguez ◽  
Diego Carrillo-Beltrán ◽  
Rancés Blanco ◽  
Juan P. Muñoz ◽  
Grettell León-Cruz ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Cancer Development ◽  
Biological Factors ◽  
Epithelial Cancers ◽  
Physical Chemical ◽  
Sensor Protein ◽  
Cupin Superfamily ◽  
Functionally Diverse ◽  
Light Chain Enhancer

Pirin is an oxidative stress (OS) sensor belonging to the functionally diverse cupin superfamily of proteins. Pirin is a suggested quercetinase and transcriptional activator of the nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) pathway. Its biological role in cancer development remains a novel area of study. This review presents accumulating evidence on the contribution of Pirin in epithelial cancers, involved signaling pathways, and as a suggested therapeutic target. Finally, we propose a model in which Pirin is upregulated by physical, chemical or biological factors involved in OS and cancer development.

scholarly journals Role of Pirin, an Oxidative Stress Sensor Protein, in Epithelial Carcinogenesis

2020 ◽  
Author(s):  
Francisco Perez-Dominguez ◽  
Diego Carrillo-Beltrán ◽  
Rancés Blanco ◽  
Juan P. Muñoz ◽  
Grettell León-Cruz ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Cancer Development ◽  
Biological Factors ◽  
Epithelial Cancers ◽  
Physical Chemical ◽  
Sensor Protein ◽  
Cupin Superfamily ◽  
Functionally Diverse ◽  
Light Chain Enhancer

Pirin is an oxidative stress (OS) sensor belonging to the functionally diverse cupin superfamily of proteins. Pirin is a suggested quercetinase and transcriptional activator of the nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) pathway. Its biological role in cancer development remains as a novel area of study. This review shows accumulating evidence on the contribution of Pirin in epithelial cancers, signaling pathways involved, and as a suggested therapeutic target. Finally, we propose a model in which Pirin is upregulated by physical, chemical or biological factors involved in OS and cancer development.

scholarly journals The Effect of Gold and Iron-Oxide Nanoparticles on Biofilm-Forming Pathogens

2013 ◽  
Vol 2013 ◽  
pp. 1-5 ◽  
Author(s):  
Madhu Bala Sathyanarayanan ◽  
Reneta Balachandranath ◽  
Yuvasri Genji Srinivasulu ◽  
Sathish Kumar Kannaiyan ◽  
Guruprakash Subbiahdoss
Keyword(s):  
Iron Oxide ◽  
Iron Oxide Nanoparticles ◽  
Immune Cells ◽  
Biofilm Formation ◽  
Bacterial Infections ◽  
Medical Applications ◽  
Oxide Nanoparticles ◽  
Biofilm Growth ◽  
Microbial Biofilms ◽  
Exopolymeric Substances

Microbial biofilms on biomaterial implants or devices are hard to eliminate by antibiotics due to their protection by exopolymeric substances that embed the organisms in a matrix, impenetrable for most antibiotics and immune-cells. Application of metals in their nanoparticulated form is currently considered to resolve bacterial infections. Gold and iron-oxide nanoparticles are widely used in different medical applications, but their utilisation to eradicate biofilms on biomaterials implants is novel. Here, we studied the effect of gold and iron oxide nanoparticles on Staphylococcus aureus and Pseudomonas aeruginosa biofilms. We report that biofilm growth was reduced at higher concentrations of gold and iron-oxide nanoparticles compared to absence of nanoparticles. Thus nanoparticles with appropriate concentration could show significant reduction in biofilm formation.

Visualization of microbial biofilms in case of digestive disorders in lambs

2021 ◽  
Vol 1 (1) ◽  
pp. 59-67
Author(s):  
E. M. Lenchenko ◽  
N. P. Sachivkina ◽  
D. A. Blumenkrants ◽  
A. Yu. Arsenyuk
Keyword(s):  
Biofilm Formation ◽  
Three Dimensional ◽  
Density Measurement ◽  
Yeast Cells ◽  
Active Growth ◽  
Microbial Structures ◽  
Microbial Biofilms ◽  
Dense Grid ◽  
Digestive Disorders ◽  
Biofilm Structure

The paper demonstrates morphometric and densitometric parameters of microbial biofilms recovered from lambs with digestive disorders. Changes of quantitative and species composition of the intestinal microbiocenoses in the lambs with digestive disorders were compared with the ones of the clinically healthy lambs. Light microscopy results demonstrated formation of three-dimensional biofilm structure in the form of dense grid consisting of gram-negative and gram-positive bacteria, yeast cells, hyphas and pseudohyphas surrounded with intracellular polymer matrix. Presence of blastospores aided to the increased number of cells attached to the substrate, and biofilm was formed, which consisted of rod and round cells attached to the microfungi cells. In the process of dispersion that occurred during the destruction of the intercellular matrix and bacterial and yeast cell detachment, branched structures separated from the microcolonies and colonized microorganism- free regions of the substrate. The intensity of biofilm formation by the microorganisms under study was evaluated by optic density measurement in 48 hours of cultivation. Fluorescence microscopy results demonstrated that the dynamics of changes of the viable microbial structures was specified by intermittent periods of increased or decreased biofilm formation intensity. Cells characterized by active growth and replication and forming alternating subpopulations were detected in the examined microbial cultures. When determining the viability of the microorganisms in the biofilms, the viable (green fluorescence) and non-viable (red fluorescence) cells were differentiated.

Experimental reedbed systems for the treatment of airport runoff

1997 ◽  
Vol 36 (8-9) ◽  
pp. 385-390 ◽  
Author(s):  
D. M. Revitt ◽  
R. B. E. Shutes ◽  
N. R. Llewellyn ◽  
P. Worrall
Keyword(s):  
Pilot Scale ◽  
Surface Flow ◽  
Pollutant Removal ◽  
Biological Processes ◽  
Metal Concentrations ◽  
Physical Chemical ◽  
Flow Systems ◽  
Total Ammonia ◽  
Removal Efficiencies

The relative efficiencies of pollutant removal from airport runoff by three different designs of pilot scale reedbed treatment systems located at Heathrow airport are described. The sub-surface flow and surface flow systems generally performed more effectively than the rafted systems for reduction of BOD, COD, total ammonia, nitrate, phosphate and metal concentrations. The variable removal efficiencies are explained in terms of the physical, chemical and biological processes which are relevant to each reedbed system.

Antimicrobial coatings against biofilm formation: the unexpected balance between antifouling and bactericidal behavior

2016 ◽  
Vol 7 (3) ◽  
pp. 656-668 ◽  
Author(s):  
Zhi Xiang Voo ◽  
Majad Khan ◽  
Qingxing Xu ◽  
Karthikeyan Narayanan ◽  
Brandon W. J. Ng ◽  
...  
Keyword(s):  
Biofilm Formation ◽  
Antimicrobial Coatings

There is a balance between antibacterial and antifouling functions, and the polymer without cationic antibacterial components effectively prevents biofilm formation.

Biologically enhanced granulated activated carbon (BAC) filtration of a mixed industrial/domestic tertiary effluent for reuse

2003 ◽  
Vol 3 (3) ◽  
pp. 17-24
Author(s):  
M. Antonelli ◽  
L. Bonomo ◽  
R. Bianchi ◽  
A. Rozzi
Keyword(s):  
Activated Carbon ◽  
Textile Industry ◽  
Pilot Scale ◽  
Process Efficiency ◽  
Hydraulic Parameters ◽  
Polishing Process ◽  
Organic Removal ◽  
Physical Chemical ◽  
Hydraulic Load ◽  
Granulated Activated Carbon

Biologically enhanced granular activated carbon (BAC) is a promising wastewater post-treatment to produce a purified effluent suitable for recycle in the textile industry. Three small pilot scale filters were used, filled with three media (two adsorbent media and one non-adsorbent), to compare two different GACs and quantify the biomass contribution to organic removal and colour abatement. A demonstrative scale filter was tested in parallel to evaluate the influence of hydraulic parameters on BAC process efficiency. Biomass contribution was significant when an acclimated biofilm grew on particles; in all cases, wastewater decolorising was due to physical-chemical adsorption only; higher hydraulic load negatively affected the polishing process. Laboratory and semi-industrial scale tests were performed on textile fibres and fabrics using samples of the effluent from the demonstrative filter. The tests confirmed the suitability of the treated water for textile reuse.

scholarly journals Effect of Coriander Oil (Coriandrum sativum) on Planktonic and Biofilm Cells of Acinetobacter baumannii

2013 ◽  
Vol 8 (5) ◽  
pp. 1934578X1300800 ◽  
Author(s):  
Andreia F. Duarte ◽  
Susana Ferreira ◽  
Rosário Oliveira ◽  
Fernanda C. Domingues
Keyword(s):  
Essential Oil ◽  
Acinetobacter Baumannii ◽  
Biofilm Formation ◽  
Antimicrobial Properties ◽  
Hospital Acquired Infections ◽  
Microtiter Plates ◽  
Crystal Violet Assay ◽  
Hospital Acquired ◽  
Microdilution Broth ◽  
Susceptibility Assay

The increasing incidence of hospital-acquired infections caused by multi-drug resistant pathogens, such as Acinetobacter baumannii, coupled with the low efficacy of drugs and rising treatment costs has created interest in the potential antimicrobial properties of natural products. The main objective of this work was to determine the effect of coriander essential oil on Acinetobacter baumannii in different growth phases, as well as its ability to inhibit the formation or eradication of biofilms. The minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) of coriander oil using a microdilution broth susceptibility assay was determined. The effects of different concentrations of coriander oil (ranging from 0.125 to 4×MIC) on biofilm formation and on established biofilm were tested using 96-well microtiter plates. Crystal violet assay was used as indicator of total biofilm biomass and the biofilm viability was assessed with a XTT staining method. It was found that coriander oil presented significant antibacterial activity against all tested strains of A. baumannii, with MIC values between 1 and 4 μL/mL. The MBC values were the same as the MIC, being an indicator of the bactericidal activity of this essential oil. In what concerns the effect of this essential oil on biofilm formation inhibition was observed of at least 85% of biomass formation by all A. baumannii strains using 2×MIC of coriander oil, in addition to a decrease in the metabolic activity of the cells. After exposure to coriander oil, a decrease in 24 h and 48 h-old biofilm biomass and metabolism was seen for all tested concentrations, even with sub-inhibitory concentrations. Coriander essential oil proved to have a significant antibacterial and anti-biofilm activity and should be considered in the development of future disinfectants to control A. baumannii dissemination.

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