scholarly journals Assessment the Epidemiological Status of Patients with Acute Liver Hepatitis Referred to Shahid Sadoughi Hospital of Yazd From 2015 to 2018

Author(s):  
Hassan Salmanroghani ◽  
Mahmud Baghbanian ◽  
Mohammad Hassan Rouzegari ◽  
Mohsen Akhondi Meybodi ◽  
Mohammad Kazem Amirbeigy

Introduction: Acute hepatitis has several causes. Transfusion of non-infected blood to the virus and avoidance of undesirable social contacts have reduced the prevalence of hepatitis B and C transmission. Improved socioeconomic status and access to healthy food and water have also reduced the prevalence of hepatitis E and A. The transition from Hyper Endimicity to Intermediate or Low Endimicity has increased the incidence of acute Hepatitis A especially in adults. The aim of this study was to determine the epidemiological status of patients with acute liver hepatitis referred to the Shahid Sadoughi Hospital of Yazd from 2015 to 2018 Methods: This cross-sectional study was performed on the patients referring to the gastrointestinal clinic of Shahid Sadoughi Hospital from 2015 to 2018. The sampling method was that after rule out chronic liver disease according to medical history and patient lab data, the patients imported to the category of acute liver disease. SPSS Inc, Chicago, IL; version 16 was used to determine the prevalence of each type of acute hepatitis.  Results: 23 patients were diagnosed with acute hepatitis, 14 were male and 9 were female. Hepatitis A was found in 15 patients, 2 patients had acute hepatitis B, 2 patients had autoimmune hepatitis, and 4 patients had other causes for hepatitis. Conclusion: 65% of patients in this study had acute hepatitis A. Therefore, acute hepatitis A is one of the important factors in the development of acute liver disease study and is therefore one of the important factors in the development of acute liver disease.  

2019 ◽  
Vol 10 (3) ◽  
Author(s):  
Iraj Shahramian ◽  
Mohammad Hassan Mohammadi ◽  
Alireza Akbari ◽  
Alireza Sargazi ◽  
Mojtaba Delaramnasab ◽  
...  

2020 ◽  
Vol 20 (5) ◽  
pp. 748-751
Author(s):  
Seyed Ali Dehghan Manshadi ◽  
Neda Alijani ◽  
Mohammadreza Salehi ◽  
Omid Dadras ◽  
SeyedAhmad SeyedAlinaghi ◽  
...  

Introduction: The aim of this study was to determine the prevalence of exposure to hepatitis A by means of serologic markers in chronic hepatitis B patients, with the secondary aim of finding the best prevention method for hepatitis A infection in susceptible groups of our setting. Methods: During the period between 2016 and 2017, we recruited 403 hepatitis B patients aged more than 14 years and regularly attending the infectious diseases clinic at a referral university hospital, Tehran, Iran. A blood sample was collected from all the patients and tested for hepatitis A IgG. The data was analyzed by SPSS v.19. Results: Although none of the patients had previously received hepatitis A vaccine, the results for serologic level of hepatitis A IgG, demonstrated positive results in 379 (94%) cases. The mean age of patients with negative and positive IgG was 29.17 and 42.46 years, respectively; the difference was statistically significant (P≤0.001). The majority of seronegative patients were young adults aged < 25 years and 25 to 35 years (P <0.001). Conclusion: Seroprevalence of hepatitis A in chronic HBV patients in Iran is high. As HBV infected patients younger than 35 years could be seronagative for HAV infection, evaluation of these patients for HAV infection and vaccination of seronegative patients would be a reasonable approach.


2016 ◽  
Vol 10 ◽  
Author(s):  
Elena Garlatti Costa ◽  
Michela Ghersetti ◽  
Silvia Grazioli ◽  
Pietro Casarin

Acute hepatitis A is generally a self-limited disease in healthy subjects within few weeks, but an uncommon type of prolonged and biphasic acute course of hepatitis A infection has been also described. This type of presentation is observed in about 6-10% of patients, but a small number of reports, concerning this topic, are available in literature. In addition hepatitis A virus (HAV) infection in hepatitis B virus (HBV) carriers has rarely been discussed. A 41-year-old Italian man, already known to our Department for HBV infection as an inactive carrier HBsAg(+)ve, experienced a prolonged and biphasic course of acute hepatitis A, lasting about 7 months. In this patient possible factors, causing the second flare of transaminases, were excluded (in particular autoimmunity). Liver biopsy as well HAV RNA search in blood/stools were not performed. In conclusion, the hepatologist should take into account this type of atypical course in patients with HAV-related hepatitis and should promote HAV vaccination in subjects with HBV-chronic hepatitis, to prevent possible life-threatening acute exacerbation of hepatic damage, mainly in HBV-carriers with more severe forms of liver diseases.


2021 ◽  
Vol 10 (3) ◽  
pp. 160-166
Author(s):  
Azka Rizvi ◽  
Naveed Ahmed ◽  
Ayesha Naeem ◽  
Waqas Saleem ◽  
Muhammad Ilyas ◽  
...  

Background: The aim and objectives of the study were to determine the knowledge, attitude and practices among biological and non-biological students regarding Hepatitis A virus (HAV) and Hepatitis E virus (HEV). Methods: The present study was conducted by the Department of Microbiology, Pakistan kidney & liver institute and research center (PKLI & RC) at University of Veterinary and Animal Sciences (UVAS), Lahore, Pakistan. The study was conducted in November, 2019 to January, 2020. A total of 326 respondents (students) participated in the present study. Respondents filled a pre-tested structured questionnaire. The variables accessed were knowledge of the diseases including etiology, mode of transmission, and prevention and control measures. Results: Most 81.56% of respondents from biological sciences (B-S) group and 51.70% from non-biological sciences (N-B-S) had awareness about HAV/HEV. Furthermore, 72.06% of respondents from BS group and 13.60% of respondents from NBS group had knowledge about the mode of transmission and spread of HAV and HEV infection. Only 16.20% of students from B-S group were aware about importance of vaccination against HAV/HEV. While a very low prevalence was found about vaccination in N-B-S group that is only 4.76%. Conclusion: The study shows significance difference in the awareness level among students from biological sciences and non-biological sciences background. Respondents were found to misunderstand the hepatitis A & E infections with hepatitis B & C, which suggests that there is need to spread awareness about the differences in their spread and severity of these infections. Awareness campaigns should be conducted to make people aware of the ways HAV/HEV spreads, its mode of transmission, severity of infection and preventive measures to minimize its spread as well as chances to acquire HAV/HEV infections.


Hepatology ◽  
2019 ◽  
Vol 70 (6) ◽  
pp. 1892-1902 ◽  
Author(s):  
Kuan‐Yin Lin ◽  
Pi‐Han Lin ◽  
Hsin‐Yun Sun ◽  
Yi‐Ting Chen ◽  
Li‐Hsin Su ◽  
...  

Hepatology ◽  
1984 ◽  
Vol 4 (3) ◽  
pp. 504-509 ◽  
Author(s):  
Kwesi N. Tsiquaye ◽  
Tim J. Harrison ◽  
Bernard Portmann ◽  
Shanlian Hu ◽  
Arie J. Zuckerman

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