scholarly journals Study of Treatment Outcome in Diabetes Mellitus Patients Receiving Directly Observed Treatment Short course (DOTS) for Pulmonary Tuberculosis in Kanyakumari Government Medical College and Hospital: A Retrospective Study

2018 ◽  
Vol 6 (9) ◽  
Author(s):  
Muthu Kumar ◽  
Keyword(s):  
Diabetes Mellitus ◽  
Treatment Outcome ◽  
Retrospective Study ◽  
Pulmonary Tuberculosis ◽  
Government Medical College ◽  
Medical College ◽  
Short Course ◽  
Directly Observed Treatment

Knowledge of Pulmonary Tuberculosis among the Patients under Anti- Tubercular Therapy

2018 ◽  
Vol 5 (1) ◽  
pp. 27-31
Author(s):  
Golam Sagir ◽  
Rafiqul Islam ◽  
Md Mamnur Rashid ◽  
Mohammad Akter Hossain ◽  
Mohammad Ashraful Haque
Keyword(s):  
Pulmonary Tuberculosis ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Medical College ◽  
Short Course ◽  
Chest Disease ◽  
Directly Observed Treatment ◽  
The Mean ◽  
Disease Hospital ◽  
Anti Tubercular Therapy

Background: Knowledge on tuberculosis is very important among the patients under anti-tubercular therapy for proper management.Objective: The purpose of the present study was to assess the knowledge about tuberculosis among patients attending the DOTS (directly observed treatment, short course) corner.Methodology: This cross sectional study was conducted in the DOTs corner of Sylhet MAG Osmani Medical College, Sylhet, Bangladesh and Sylhet Chest Disease Hospital, Sylhet, Bangladesh during the period from June 2011 to November 2011 for a period of six (6) months. All the patients who were diagnosed as case of pulmonary tuberculosis and were treated with anti-tubercular drugs at DOTs corner who attended in the both Hospitals, Sylhet were selected as study population.Result: The age of the patients ranged from 18 to 70 years with the mean age of 41.2 (SD+ 12.4) years. The age of the male patients were ranging from 18 to 70 years with the mean age of 42.1 (SD: 12.8) years. Among the 194 patients, 90(46.4%) patients had good knowledge and 104(53.6%) patients had poor knowledge about tuberculosis.Conclusion: In conclusion, greater efforts therefore need to be undertaken to improve TB control among TB patients through appropriate and sustainable health education.Bangladesh Journal of Infectious Diseases 2018;5(1):27-31

scholarly journals Effect of Diabetes Mellitus on Tuberculosis Treatment Outcome and Adverse Reactions in Patients Receiving Directly Observed Treatment Strategy in India: A Prospective Study

2016 ◽  
Vol 2016 ◽  
pp. 1-11 ◽  
Author(s):  
Ali Nasir Siddiqui ◽  
Khalid Umer Khayyam ◽  
Manju Sharma
Keyword(s):  
Diabetes Mellitus ◽  
Treatment Outcome ◽  
Prospective Study ◽  
Urban Slum ◽  
Successful Implementation ◽  
Short Course ◽  
Directly Observed Treatment ◽  
Sputum Conversion ◽  
Primary Health Care Centers ◽  
A Prospective Study

Despite successful implementation of directly observed treatment, short course (DOTS) in India, the growing number of diabetes mellitus (DM) patients appears to be a cause in the increasing tuberculosis (TB) incidence, affecting their management. In this regard, a prospective study was conducted on DOTS patients in three primary health care centers in urban slum region of South Delhi, India, to evaluate the effect of DM on sputum conversion, treatment outcome, and adverse drug reactions (ADR) due to anti-TB treatment. Eligible TB patients underwent blood glucose screening at treatment initiation. Disease presentation, clinical outcome, and ADRs were compared between patients of TB with and without DM. Out of 316 patients, the prevalence of DM was found to be 15.8%, in which 19.4% and 9.6% were PTB and EPTB patients, respectively. DM patients have observed higher sputum positivity (OR 1.247 95% CI; 0.539–2.886) at the end of 2-month treatment and poor outcome (OR 1.176 95% CI; 0.310–4.457) at the completion of treatment compared with non DM patients. Presence of DM was significantly associated (OR 3.578 95% CI; 1.114–11.494,p=0.032) with the development of ADRs. DM influences the treatment outcome of PTB patients in our setting and also on the ADR incidence.

Impact of diabetes on clinical presentation and treatment outcome of pulmonary tuberculosis in Beijing

2014 ◽  
Vol 143 (1) ◽  
pp. 150-156 ◽  
Author(s):  
C. HONGGUANG ◽  
L. MIN ◽  
J. SHIWEN ◽  
G. FANGHUI ◽  
H. SHAOPING ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Treatment Outcome ◽  
Pulmonary Tuberculosis ◽  
Odds Ratio ◽  
Clinical Presentation ◽  
Underlying Mechanism ◽  
Urban Setting ◽  
Sputum Smear ◽  
Positive Sputum Smear ◽  
The Impact

SUMMARYDiabetes mellitus (DM) is currently known to be one of the risk factors for pulmonary tuberculosis (PTB) and the proportion of DM in PTB is rising along with the increased prevalence of DM in countries with high PTB burden. This study was designed to explore the impact of DM on clinical presentation and treatment outcome of PTB in China. In an urban setting in Beijing, 1126 PTB patients, 30·6% with positive sputum smear, registered in two PTB dispensaries from January 2010 to December 2011 were screened for DM and were followed up prospectively during PTB treatment. DM was observed in 16·2% of patients with PTB. PTB with DM appeared to be associated with older age and a higher proportion of re-treatment. On presentation, DM was associated with more severe PTB signs with higher proportions of smear positivity [odds ratio (OR) 2·533, 95% confidence interval (CI) 1·779–3·606], cavity (OR 2·253, 95% CI 1·549–3·276) and more symptoms (OR 1·779, 95% CI 1·176–2·690). DM was also associated with non-TB deaths (OR 5·580, 95% CI 2·182–14·270, P < 0·001) and treatment failure (OR 6·696, 95% CI 2·019–22·200, P = 0·002). In Beijing, the findings of this study underlined the need to perform early bi-directional screening programmes and explore the underlying mechanism for different treatment outcomes for PTB with DM.

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