Progesterone-induced blocking factor: from molecular biology to clinical medicine

2021 ◽  
Vol 5_2021 ◽  
pp. 64-71
Author(s):  
Prokhorova O.V. Prokhorova O ◽  
Olina A.A. Olina ◽  
Tolibova G.Kh. Tolibova ◽  
Tral T.G. Tral T ◽  
◽  
...  
Keyword(s):  
Molecular Biology ◽  
Clinical Medicine ◽  
Blocking Factor

Endogenous opioids and related peptides: from molecular biology to clinical medicine The Sir Henry Dale Lecture for 1985

1985 ◽  
Vol 107 (2) ◽  
pp. 147-157 ◽  
Author(s):  
H. Imura ◽  
Y. Kato ◽  
Y. Nakai ◽  
K. Nakao ◽  
I. Tanaka ◽  
...  
Keyword(s):  
Molecular Biology ◽  
Opioid Receptors ◽  
Clinical Medicine ◽  
Biological Activities ◽  
Opioid Peptide ◽  
Endogenous Opioids ◽  
The Body ◽  
Molecular Forms ◽  
Protein Chemistry ◽  
Precursor Proteins

ABSTRACT Advances in techniques in molecular biology have facilitated the research into endogenous opioids and related peptides in several ways. The organization and expression of genes and the primary structure of three precursor proteins of opioid peptides have been elucidated. These studies predicted the presence of potentially bioactive peptides, which has been confirmed by later studies. Advances in techniques in protein chemistry have helped to elucidate the distribution and molecular forms of endogenous opioids and related peptides in the body, and the processing of precursor proteins. Studies on the function of these peptides have shown a broad spectrum of actions. Leumorphin, a newly identified peptide, has been shown to exhibit unique biological activities. In spite of extensive studies, the physiological and pathophysiological significance of opioid peptide systems are not yet completely understood. This is mainly due to the paucity of our knowledge about opioid receptors. Further studies on the subtypes of opioid receptors will help to elucidate all aspects of the function of endogenous opioids and related peptides. J. Endocr. (1985) 107, 147–157

scholarly journals Fungal physiology and the origins of molecular biology

Microbiology ◽  
2009 ◽  
Vol 155 (12) ◽  
pp. 3799-3809 ◽  
Author(s):  
Robert Brambl
Keyword(s):  
Molecular Biology ◽  
Stress Responses ◽  
Clinical Medicine ◽  
Cell Signalling ◽  
Fungal Cell ◽  
Experimental Systems ◽  
Hyphal Morphogenesis ◽  
New Research ◽  
The Relationship ◽  
Basic Insight

Molecular biology has several distinct origins, but especially important are those contributed by fungal and yeast physiology, biochemistry and genetics. From the first gene action studies that became the basis of our understanding of the relationship between genes and proteins, through chromosome structure, mitochondrial genetics and membrane biogenesis, gene silencing and circadian clocks, studies with these organisms have yielded basic insight into these processes applicable to all eukaryotes. Examples are cited of pioneering studies with fungi that have stimulated new research in clinical medicine and agriculture; these studies include sexual interactions, cell stress responses, the cytoskeleton and pathogenesis. Studies with the yeasts and fungi have been effective in applying the techniques and insights gained from other types of experimental systems to research in fungal cell signalling, cell development and hyphal morphogenesis.

Hemoglobinopathies in Southeast Asia: Molecular Biology and Clinical Medicine

Hemoglobin ◽  
1997 ◽  
Vol 21 (4) ◽  
pp. 299-319 ◽  
Author(s):  
Suthat Fucharoen ◽  
Pranee Winichagoon
Keyword(s):  
Molecular Biology ◽  
Southeast Asia ◽  
Clinical Medicine

scholarly journals Rationale in Usage of Immunomodulators for Management of Head, Face and Neck Cancers

2012 ◽  
Vol 3 (3) ◽  
pp. 154-157
Author(s):  
Sonal Vahanwala ◽  
Sandeep S Pagare ◽  
Runuk Singhi ◽  
Chaitanya D Nayak
Keyword(s):  
Immune System ◽  
Molecular Biology ◽  
Clinical Medicine ◽  
Entire System ◽  
Major Difficulty ◽  
Immune Defect ◽  
Acquired Immunodeficiency ◽  
To Come ◽  
Immunodeficiency Syndrome ◽  
Insight Into

ABSTRACT Recent advances in molecular biology have provided insight into the complex network of interaction that occurs within the immune system. The use of specific Immunomodulators to strengthen a deficient immune system or bolster a normal immune system presents a unique strategy for the treatment of various disorders that will clearly affect the practice of clinical medicine for many years to come. A major difficulty limiting the use of immunomodulators in clinical medicine has been the complexity of the immunoregulatory network in which modulation of one component usually perturbs the entire system, thus diminishing the specificity of the approach. Several immunomodulators are currently being tested in the treatment of the immune defect of the acquired immunodeficiency syndrome. This article covers the types of immunomodulators, their mechanism of action and their applications. How to cite this article Pagare SS, Singhi R, Vahanwala S Nayak CD. Rationale in Usage of Immunomodulators for Management of Head, Face and Neck Cancers. Int J Head and Neck Surg 2012;3(3):154-157.

scholarly journals Looking into the crystal ball – Swedish radiology 2025. A qualitative study of possible future scenarios

2015 ◽  
Vol 2 (1) ◽  
pp. 15-29 ◽  
Author(s):  
Kent Fridell ◽  
Jessica Ekberg
Keyword(s):  
Information Technology ◽  
Nuclear Medicine ◽  
Molecular Biology ◽  
Qualitative Study ◽  
Clinical Medicine ◽  
Scenario Planning ◽  
Strategy Management ◽  
Future Scenarios ◽  
Crystal Ball ◽  
Management Method

During the 20th century, the field of radiology experienced extraordinary growth and became an essential component of the practice of clinical medicine (Chan, 2002). In the 21st century, it is likely that radiology will continue to grow by interfacing with new and important domains such as information technology, molecular biology new tracers in nuclear medicine. This will require radiologists to understand the gaps between the new frontiers and the traditional core of radiology.This article introduce the reader to one strategy management method, Scenario Planning, to identify, analyze and present four scenarios for the Swedish Radiology 2025. It also presents the trends that will affect the future of radiology

scholarly journals A scientometric overview of CORD-19

2020 ◽  
Author(s):  
Giovanni Colavizza ◽  
Rodrigo Costas ◽  
Vincent A. Traag ◽  
Nees Jan van Eck ◽  
Thed van Leeuwen ◽  
...  
Keyword(s):  
Public Health ◽  
Social Media ◽  
Molecular Biology ◽  
Web Of Science ◽  
Clinical Medicine ◽  
Complete Coverage ◽  
Research Areas ◽  
The Web

AbstractAs the COVID-19 pandemic unfolds, researchers from all disciplines are coming together and contributing their expertise. CORD-19, a dataset of COVID-19 and coronavirus publications, has been made available along-side calls to help mine the information it contains and to create tools to search it more effectively. We analyse the delineation of the publications included in CORD-19 from a scientometric perspective. Based on a comparison to the Web of Science database, we find that CORD-19 provides an almost complete coverage of research on COVID-19 and coronaviruses. CORD-19 contains not only research that deals directly with COVID-19 and coronaviruses, but also research on viruses in general. Publications from CORD-19 focus mostly on a few well-defined research areas, in particular: coronaviruses (primarily SARS-CoV, MERS-CoV and SARS-CoV-2); public health and viral epidemics; molecular biology of viruses; influenza and other families of viruses; immunology and antivirals; clinical medicine. CORD-19 publications that appeared in 2020, especially editorials and letters, are disproportionately popular on social media. While we fully endorse the CORD-19 initiative, it is important to be aware that CORD-19 extends beyond research on COVID-19 and coronaviruses.

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