scholarly journals Rationale in Usage of Immunomodulators for Management of Head, Face and Neck Cancers

2012 ◽  
Vol 3 (3) ◽  
pp. 154-157
Author(s):  
Sonal Vahanwala ◽  
Sandeep S Pagare ◽  
Runuk Singhi ◽  
Chaitanya D Nayak

ABSTRACT Recent advances in molecular biology have provided insight into the complex network of interaction that occurs within the immune system. The use of specific Immunomodulators to strengthen a deficient immune system or bolster a normal immune system presents a unique strategy for the treatment of various disorders that will clearly affect the practice of clinical medicine for many years to come. A major difficulty limiting the use of immunomodulators in clinical medicine has been the complexity of the immunoregulatory network in which modulation of one component usually perturbs the entire system, thus diminishing the specificity of the approach. Several immunomodulators are currently being tested in the treatment of the immune defect of the acquired immunodeficiency syndrome. This article covers the types of immunomodulators, their mechanism of action and their applications. How to cite this article Pagare SS, Singhi R, Vahanwala S Nayak CD. Rationale in Usage of Immunomodulators for Management of Head, Face and Neck Cancers. Int J Head and Neck Surg 2012;3(3):154-157.

PEDIATRICS ◽  
1993 ◽  
Vol 92 (4) ◽  
pp. 636-636
Author(s):  
ANDREW F. SHORR

Futterman et al provide interesting insight into the spread of the human immunodeficiency virus (HIV) among adolescents in New York City and into the impact the acquired immunodeficiency syndrome (AIDS) has had on this population. In their conclusion, however, they misrepresent the data regarding HIV and AIDS among youth. More specifically, they write, "Reported AIDS cases among adolescents increased by over 77% over the past two years. . ." By using cumulative percent data for AIDS cases, they distort the true picture. The actual data reveal that the number of AIDS cases in this population has dropped during the past year.


2016 ◽  
Vol 3 (3) ◽  
Author(s):  
Mohmad Iqbal

Literally the phrasal acronym HIV/AIDS would prove a leitmotif in this study. AIDS is the final stage of HIV infection, and not everyone who has HIV advances to this stage. At this stage people are susceptible to opportunistic infections because of their damaged immune system. So a person progressed to too many opportunistic infections means he has AIDS. He also may show very little CD4 count. A person at this stage is bound to go for medical, salubrious, and therapeutic intervention to avoid the extreme results and death sentence. HIV epidemic has a well-documented and well understood progression. Untreated, HIV is almost universally fatal because it eventually damages the immune system—resulting in acquired immunodeficiency syndrome (AIDS). HIV treatment (antiretroviral therapy) helps people at all stages of the disease, and treatment can slow or prevent progression from one stage to the next. As yet no vaccine or drug has been made by the medical sciences that ensure the complete eradication of virus from the body. The available drugs surely can stop the growth of virus, or lessen the multiplication of it. These drugs have been responsible for the longevity of the HIV infected.


CNS Spectrums ◽  
2000 ◽  
Vol 5 (5) ◽  
pp. 25-32 ◽  
Author(s):  
Mary D. Tyll ◽  
Karl Goodkin ◽  
Nancy T. Blaney ◽  
Teri T. Baldewicz ◽  
Jodi Dee Hunt ◽  
...  

AbstractPsychoneuroimmunology (PNI) is a rapidly evolving multidisciplinary field founded on the premise that psychosocial factors, the central nervous system, and the immune system are intimately linked. Following publication of scientific evidence supporting this link, a number of animal and human studies have been published, both inside and outside the area of human immunodeficiency virus (HIV) infection and acquired immunodeficiency syndrome. These studies support the existence of bidirectional feedback mechanisms operating between the brain and the immune system. To date, however, there is no all-encompassing model that predicts individual differences in the relationship among psychosocial factors, immunologic measures, and clinical disease progression in HIV type 1 (HIV-1) infection. This variability in human response has been explained by a number of cofactors (host as well as environmental) that appear to accelerate the course of the disease.Since psychosocial factors are highly amenable to behavioral interventions, several models for intervention research have been proposed to evaluate whether such interventions can enhance immune functioning, thereby curtailing disease progression. Examination of these interventions in the context of PNI and HIV-1 infection, however, is rather limited. Therefore, researchers and clinicians must not only consider conceptualizations and paradigms in this area of research, but also focus on empirically testable, theory-driven models that allow for the unique characteristics of individual patients.


Author(s):  
Alex Merlin

HIV (human immunodeficiency virus) is a virus that attacks the body's immune system. If HIV is not treated, it can lead to AIDS (acquired immunodeficiency syndrome). There is currently no effective cure. Once people get HIV, they have it for life. But with proper medical care, HIV can be controlled. OBJECTIVES: To assess the level of knowledge regarding HIV/AIDS among young adults in selected areas, Mumbai. H1 -There is significant association between the level of knowledge with selected demographic variables. Research Design – Survey method. Sample Size – 150 Young adults. CONCLUSION: As per the survey, among 150 young adults, 65 young adults had poor level of knowledge regarding HIV/AIDS. This showing a significant reduction in the level of knowledge.


2019 ◽  
Author(s):  
Sorush Niknamian

Ebola, is a virus. It incubates for 2 to 21 days and then roars to life to induce death. Ebola first tricks the immune system into thinking nothing is there. The virus enters many different types of cells in human body. It multiplies extremely rapidly, emerges from the cell to infect yet more. Interestingly, much of the damage induced by the infections is actually the suppressed immune system awakening and then shooting cannons at everything, inclusive of one’s own cells. This causes great inflammation, leakages in hemorrhages, extreme oxygen starvation to tissues and organ failure. The human immunodeficiency virus (HIV) is a lentivirus a subgroup of retrovirus, that causes HIV infection and over time acquired immunodeficiency syndrome (AIDS). This research has shown how medical ozone therapy can be an effective treatment in the mentioned viral diseases which has caused millions of death every year in the world.


1991 ◽  
Vol 4 (5) ◽  
pp. 326-341
Author(s):  
Stan G. Louie ◽  
George S. Jaresko

This article examines the use of classical as well as novel immunological agents to augment the immune system. Strategies to prevent infectious disease using vaccines to prime the immune system are discussed. A prospective overview of acquired immunodeficiency syndrome (AIDS) vaccine development provides insights into the possible agents that may be developed in the near future. The rationale for the use of intravenous immunoglobulin and colony stimulating factors in selected clinical situations is also discussed.


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