Prevalence of Generalized Swine Tuberculosis with Special Reference to Pathological Study in Middle Gangetic Plain Zone of Uttar Pradesh

Background: Swine tuberculosis (TB) is a highly progressive granulomatous infectious disease. The cases usually go undiagnosed and become a potent source of infection to other animals and humans. In Ayodhya and Sultanpur districts, no such study has been conducted so far. Keeping in view the zoonotic importance of this disease, the present study was, therefore, designed to study the prevalence of generalized swine tuberculosis in middle gangetic plain zone of Eastern Uttar Pradesh. Methods: Forty-two (42) pigs were presented for postmortem at Department of Veterinary Pathology, C.V. Sc. and A.H., ANDUAT, Ayodhya from nearby villages of Ayodhya and Sultanpur districts from April 2017 to February 2020. Pigs were screened for typical lesions of tubercles throughout the body during postmortem examination.Result: The prevalence was 7.14% out of 42 pigs presented for postmortem examination. Eight pigs (19.04%) had nodules in either lungs or liver but these were diagnosed negative for TB on ZN (Ziehl-Neelsen) staining. Typical tubercles were evident in liver, spleen and lungs and were characterized by the presence of circumscribed yellowish white raised lesions of various sizes and numbers. Microscopically, granulomatous lesions revealed necrotic areas surrounded by mixed inflammatory cells including macrophages, lymphocytes and plasma cells. The ZN stain reveals presence of acid fast bacilli in impression smear made from lung, spleen and liver.

Download Full-text

Transforming Margins Through Resistance, Articulation and Politics

Society and Culture in South Asia ◽

10.1177/2393861720923050 ◽

2020 ◽

Vol 6 (2) ◽

pp. 273-303

Author(s):

Shilp Shikha Singh

Keyword(s):

Uttar Pradesh ◽

The Body ◽

Body Politics ◽

The Political ◽

Political Awareness ◽

Life Chances ◽

Modern Politics ◽

Eastern Uttar Pradesh

The processes of democracy in India have inter alia increased the political awareness of those who are violated to be and to remain at the margins of the body politics. The unmet aspirations are countered in multiple ways—Resistance: spontaneous violent outburst among the marginalised; Articulation: action mediated by an outside agency committed to increasing democratic space and life chances of those at the margin; Politics: Increased participation of those at the margin in the institutionalised democratic processes. Focusing on the case of a marginal Dalit community of Eastern Uttar Pradesh the paper documents the form resistances emerging from margins of society. The research charts the evolution of political aspiration amongst the Musahar community in the last two decades with its interface with development and modern politics.

Download Full-text

ASTERACEOUS FLORA OF TERAI REGION OF EASTERN UTTAR PRADESH, INDIA

FLORA AND FAUNA ◽

10.33451/florafauna.v23i1pp105-114 ◽

2017 ◽

Vol 23 (1) ◽

Author(s):

KANCHAN LATA

Keyword(s):

Uttar Pradesh ◽

Eastern Uttar Pradesh ◽

Systematic Identification

The systematic identification of 78 species belonging to 51 genera reported from Terai region of Eastern Uttar Pradesh, India. The present paper provides key to genera, list of plant with their habit, phenology and voucher number of each species.

Download Full-text

Rotavirus Gastroenteritis in Eastern Uttar Pradesh, India

The Indian Journal of Pediatrics ◽

10.1007/s12098-020-03625-0 ◽

2021 ◽

Cited By ~ 1

Author(s):

Vineeta Gupta ◽

Priyanka Aggarwal ◽

Brajesh Kumar ◽

Nayana P. Nair ◽

Varunkumar Thiyagarajan ◽

...

Keyword(s):

Uttar Pradesh ◽

Rotavirus Gastroenteritis ◽

Eastern Uttar Pradesh

Download Full-text

Inflammation-Related Carcinogenesis: Lessons from Animal Models to Clinical Aspects

Cancers ◽

10.3390/cancers13040921 ◽

2021 ◽

Vol 13 (4) ◽

pp. 921

Author(s):

Futoshi Okada ◽

Runa Izutsu ◽

Keisuke Goto ◽

Mitsuhiko Osaki

Keyword(s):

Animal Models ◽

Tissue Injury ◽

Economic Status ◽

Gene Mutations ◽

Inflammatory Cells ◽

The Body ◽

Clinical Aspects ◽

Promote Cell Proliferation ◽

Organ Specific ◽

Altered Gene

Inflammation-related carcinogenesis has long been known as one of the carcinogenesis patterns in humans. Common carcinogenic factors are inflammation caused by infection with pathogens or the uptake of foreign substances from the environment into the body. Inflammation-related carcinogenesis as a cause for cancer-related death worldwide accounts for approximately 20%, and the incidence varies widely by continent, country, and even region of the country and can be affected by economic status or development. Many novel approaches are currently available concerning the development of animal models to elucidate inflammation-related carcinogenesis. By learning from the oldest to the latest animal models for each organ, we sought to uncover the essential common causes of inflammation-related carcinogenesis. This review confirmed that a common etiology of organ-specific animal models that mimic human inflammation-related carcinogenesis is prolonged exudation of inflammatory cells. Genotoxicity or epigenetic modifications by inflammatory cells resulted in gene mutations or altered gene expression, respectively. Inflammatory cytokines/growth factors released from inflammatory cells promote cell proliferation and repair tissue injury, and inflammation serves as a “carcinogenic niche”, because these fundamental biological events are common to all types of carcinogenesis, not just inflammation-related carcinogenesis. Since clinical strategies are needed to prevent carcinogenesis, we propose the therapeutic apheresis of inflammatory cells as a means of eliminating fundamental cause of inflammation-related carcinogenesis.

Download Full-text

Cyanophycean Algae from Eastern Uttar Pradesh, India

Ecoprint An International Journal of Ecology ◽

10.3126/eco.v13i0.1627 ◽

2009 ◽

Vol 13 ◽

pp. 35-39 ◽

Cited By ~ 1

Author(s):

P. K. Mishra ◽

R. K. Mehrotra ◽

Madhulika Shukla ◽

Jai Prakash ◽

Purnima Mishra

Keyword(s):

Uttar Pradesh ◽

Eastern Uttar Pradesh ◽

First Time

In the present paper 10 Cyanophycean algae belonging 10 genera have been described from eastern U.P. The genera described are: Chroococcus, Microcystis, Aphanothece, Arthrospira, Spirulina, Lyngbya, Anabaena, Rivularia, and Gloeotrichia. All these forms are being reported for the first time from eastern U.P., India.doi: 10.3126/eco.v13i0.1627Key words: Cyanophycean algaeEcoprint (An International Journal of Ecology) Vol. 13, No. 1, 2006 Page: 35-39

Download Full-text

Evidence for the Origin of Plasma Cells from Adventitial Cells

Blood ◽

10.1182/blood.v29.1.41.41 ◽

1967 ◽

Vol 29 (1) ◽

pp. 41-56 ◽

Cited By ~ 1

Author(s):

MOTOE HIRATA-HIBI

Keyword(s):

Plasma Cells ◽

Inflammatory Cells ◽

Neutral Red ◽

Dorsal Skin ◽

Connective Tissues ◽

Chromatin Pattern ◽

Adventitial Cells ◽

Subcutaneous Connective Tissue ◽

Diffuse Distribution

Abstract Arthus reactions were induced in the dorsal skin, and the subcutaneous connective tissues from the sensitized areas were examined at various stages. The subcutaneous connective tissue was used due to its simplicity of construction and because it could be studied conveniently by both supravital and fixed methods. This combination of tissue and technic allowed both an accurate classification of various types of inflammatory cells and a close examination of their relationships to the blood vessels. Cells transitional between adventitial cells and plasma cells were observed after antigenic stimulation. Their location on the walls of the venules and capillaries indicated that they were adventitial cells but their morphology was that of plasma cells. By supravital technic they exhibited a glassy and homogeneous cytoplasm, a circular formation of neutral red granules, and a diffuse distribution of Janus green granules; and by fixed method they exhibited a chromatin pattern similar to that of plasma cells, an increased cytoplasmic basophilia, and a nucleolus was often present. Small plasma cells appeared simultaneously around the venules and capillaries. The local origin of plasma cells would appear to explain the absence of plasmacytosis during strong tissue plasma cell reactions. Immunofluorescence was only found in plasma cells and in transitional adventitial cells, indicating a functional similarity between the 2 cells.

Download Full-text

Spectrum of hemoglobinopathies in Eastern Uttar Pradesh

The Indian Journal of Pediatrics ◽

10.1007/s12098-009-0105-2 ◽

2009 ◽

Vol 76 (8) ◽

pp. 857-857 ◽

Cited By ~ 1

Author(s):

Vineeta Gupta ◽

Jyoti Shukla ◽

Vijai Tilak ◽

Baldev Bhatia

Keyword(s):

Uttar Pradesh ◽

Eastern Uttar Pradesh

Download Full-text

Morphometric analysis of collagen and inflammatory cells in periodontal disease

Vojnosanitetski pregled ◽

10.2298/vsp130627076g ◽

2015 ◽

Vol 72 (3) ◽

pp. 219-224 ◽

Cited By ~ 4

Author(s):

Ranko Golijanin ◽

Bojan Kujundzic ◽

Zoran Milosavljevic ◽

Dragan Milovanovic ◽

Zlatibor Andjelkovic ◽

...

Keyword(s):

Periodontal Disease ◽

Morphometric Analysis ◽

Plasma Cells ◽

Relative Proportion ◽

Inflammatory Cells ◽

Test System ◽

Clinical Staging ◽

Gingival Tissue ◽

Tissue Destruction ◽

Immunochemical Method

Background/Aim. Periodontal disease affects gingival tissue and supporting apparatus of the teeth leading to its decay. The aim of this study was to highlight and precisely determine histological changes in the gum tissue. Methods. Gingival biopsy samples from 53 healthy and parodontopathy-affected patients were used. Clinical staging of the disease was performed. Tissue specimens were fixed and routinely processed. Sections, 5 ?m thin, were stained with hematoxylin and eosin, histochemical Van-Gieson for the collagen content, Spicer method for mast-cells and immunochemical method with anti-CD68 and anti-CD38 for the labelling of the macrophages and plasma-cells. Morphometric analysis was performed by a M42 test system. Results. While the disease advanced, collagen and fibroblast volume density decreased almost twice in the severe cases compared to the control ones, but a significant variation was observed within the investigated groups. The mast-cell number increased nearly two times, while the macrophage content was up to three times higher in severe parodontopathy than in healthy gingival tissue. However, the relative proportion of these cells stayed around 6% in all cases. Plasma-cells had the most prominent increase in the number (over 8 times) compared to the control, but again, a variation within investigated groups was very high. Conclusion. Gingival tissue destruction caused by inflammatory process leads to significant changes in collagen density and population of resident connective tissue cells. Although inflammatory cells dominated with the disease advancing, a high variation within the same investigated groups suggests fluctuation of the pathological process. This article has been corrected. Link to the correction <a href="http://dx.doi.org/10.2298/VSP1704391E">10.2298/VSP1704391E</a>

Download Full-text