Infantile hemangioma: current classification, clinical picture and effective methods of therapy

2016 ◽  
Vol 19 (3) ◽  
pp. 178-183
Author(s):  
Oleg V. Sheptiy ◽  
L. S Kruglova
Keyword(s):  
Topical Therapy ◽  
Infantile Hemangioma ◽  
Cochrane Library ◽  
Functional Disorders ◽  
Review Of The Literature ◽  
Current Classification ◽  
Phases Of Development ◽  
Spontaneous Involution ◽  
Β Blockers ◽  
The Cochrane Library

Review of the literature devoted to one of the most common tumors of childhood - hemangioma is presented. Literature search was performed using the NCBI, including PubMed, PubMed Health, and The Cochrane Library databases. Infantile hemangioma is a neoplastic proliferation of endothelial cells, which is characterized by different phases of development: proliferation and spontaneous involution. The types of infantile hemangiomas, variants of the course and possible complications such as ulceration, functional disorders, and the formation of cosmetic defects are described. Incidence associated with infantile hemangioma syndrome is presented. The current views on the pathogenesis of infantile hemangiomas are described. Information about the best methods of diagnostic imaging, as well as medical and surgical therapies, including systemic and topical therapy with β-blockers, corticosteroids and use of lasers are described.

scholarly journals A Systematic Review of the Literature on Early Vocalizations and Babbling Patterns in Young Children

2018 ◽  
Vol 40 (1) ◽  
pp. 3-14 ◽  
Author(s):  
Lydia Morgan ◽  
Yvonne E. Wren
Keyword(s):  
Systematic Review ◽  
Case Series ◽  
Speech Development ◽  
Cochrane Library ◽  
Bibliographic Databases ◽  
Review Of The Literature ◽  
Phonological Acquisition ◽  
Future Studies ◽  
The Cochrane Library ◽  
Children's Speech

Children’s speech development begins in infancy. The pattern of this development has been explored in studies over a number of years using a range of research methodology and approaches to investigation. A systematic review of the existing literature was carried out to determine the collective contribution of this literature to our understanding of early vocalizations and babbling through the period 9 to 18 months. Eight bibliographic databases were searched as well as the Cochrane library. Thirteen studies were identified for inclusion, which were mostly longitudinal observational case series. The review identified progressive increases in the complexity and volume of infants’ early vocalizations through the period. It also found a broad order of phonological acquisition. Although the studies in this review demonstrated marked individual variation, the review provides indicative patterns of development which can be used as a basis to explore relationships with later speech development in future studies.

scholarly journals The Best Anticoagulation Strategy for Cirrhotic Patients who Underwent Splenectomy: A Network Meta-Analysis

2017 ◽  
Vol 2017 ◽  
pp. 1-9 ◽  
Author(s):  
Cheng Gong ◽  
Xian Qin ◽  
Jian Yang ◽  
Tao Guo
Keyword(s):  
Antithrombin Iii ◽  
Meta Analysis ◽  
Therapeutic Strategies ◽  
Cochrane Library ◽  
Cumulative Probability ◽  
Review Of The Literature ◽  
Good Convergence ◽  
First Choice ◽  
Cirrhotic Patients ◽  
The Cochrane Library

Objective. To determine the best anticoagulation strategy for the patients who underwent splenectomy with cirrhosis through network meta-analysis. Methods. We conducted a systematic review of the literature in PubMed, Embase, and the Cochrane Library database. We extracted data on incidence of Portal vein system thrombosis (PVST) from studies that compared various anticoagulation strategies for use with patients who underwent splenectomy with cirrhosis. Network meta-analysis was conducted in ADDIS by evaluating the different incidence of PVST. Consistency and inconsistency models were developed to identify differences among the therapeutic strategies. Cumulative probability was utilized to rank the strategies under examination. Results. A total of 11 studies containing 1153 patients were included in the network meta-analysis. The results revealed that the application of Antithrombin III was the best anticoagulation option for patients who underwent splenectomy with cirrhosis (P=0.59). The data of consistency and inconsistency models exhibited basically consistent and showed good convergence. Conclusions. Application of Antithrombin III seemed to be the best anticoagulation strategy for cirrhotic patients who underwent splenectomy and should be considered a first-choice clinical reference.

scholarly journals Chemotherapy-induced peripheral neuropathies: an integrative review of the literature

2015 ◽  
Vol 49 (2) ◽  
pp. 0335-0345 ◽  
Author(s):  
Talita Cassanta Costa ◽  
Miriam Lopes ◽  
Anna Cláudia Yokoyama dos Anjos ◽  
Marcia Maria Fontão Zago
Keyword(s):  
Latin American ◽  
Health Sciences ◽  
Integrative Review ◽  
Cochrane Library ◽  
Peripheral Neuropathies ◽  
Review Of The Literature ◽  
Electronic Library ◽  
The Cochrane Library ◽  
Chemotherapy Agents ◽  
Positive Results

OBJECTIVE: To identify scientific studies and to deepen the knowledge of peripheral neuropathies induced by chemotherapy antineoplastic, seeking evidence for assistance to cancer patients. METHOD: Integrative review of the literature conducted in the databases Latin American and Caribbean Health Sciences (LILACS), Scientific Electronic Library Online (SciELO), Medical Literature Analysis (PubMed/MEDLINE), the Cochrane Library and the Spanish Bibliographic Index Health Sciences (IBECS). RESULTS: The sample consisted of 15 studies published between 2005-2014 that met the inclusion criteria. Studies showed aspects related to advanced age, main symptoms of neuropathy and chemotherapy agents as important adverse effect of neuropathy. CONCLUSION: We identified a small number of studies that addressed the topic, as well as low production of evidence related to interventions with positive results. It is considered important to develop new studies proposed for the prevention and/or treatment, enabling adjustment of the patient's cancer chemotherapy and consequently better service.

scholarly journals Real-time Inferential Analytics Based on Online Databases of Trends: A Breakthrough Within the Discipline of Digital Epidemiology of Dentistry and Oral-Maxillofacial Surgery

2019 ◽  
Vol 13 (2) ◽  
pp. 81 ◽  
Author(s):  
Ahmed Al-Imam ◽  
Usama Khalid ◽  
Nawfal Al-Hadithi ◽  
Dawoude Kaouche
Keyword(s):  
Statistical Analysis ◽  
Statistical Inference ◽  
Real Time ◽  
Machine Learning Algorithms ◽  
Google Trends ◽  
Cochrane Library ◽  
Review Of The Literature ◽  
Dental Anatomy ◽  
Digital Epidemiology ◽  
The Cochrane Library

Background: Epidemiological sciences have been evolving at an exponential rate paralleled only by the comparable growth within the discipline of data science. Digital epidemiological studies are playing a vital role in medical science analytics for the past few decades. To date, there are no published attempts at deploying the use of real-time analytics in connection with the disciplines of Dentistry or Medicine. Aims and Objectives: We deployed a real-time statistical analysis in connection with topics in Dental Anatomy and Dental Pathology represented by the maxillary sinus, posterior maxillary teeth, related oral pathology. The purpose is to infer the digital epidemiology based on a continuous stream of raw data retrieved from Google Trends database. Materials and Methods: Statistical analysis was carried out via Microsoft Excel 2016 and SPSS version 24. Google Trends database was used to retrieve data for digital epidemiology. Real-time analysis and the statistical inference were based on encoding a programming script using Python high-level programming language. A systematic review of the literature was carried out via PubMed-NCBI, the Cochrane Library, and Elsevier databases. Results: The comprehensive review of the literature, based on specific keywords search, yielded 491813 published studies. These were distributed as 488884 (PubMed-NCBI), 1611 (the Cochrane Library), and 1318 (Elsevier). However, there was no single study attempting real-time analytics. Nevertheless, we succeeded in achieving an automated real-time stream of data accompanied by a statistical inference based on data extrapolated from Google Trends. Conclusion: Real-time analytics are of considerable impact when implemented in biological and life sciences as they will tremendously reduce the required resources for research. Predictive analytics, based on artificial neural networks and machine learning algorithms, can be the next step to be deployed in continuation of the real-time systems to prognosticate changes in the temporal trends and the digital epidemiology of phenomena of interest.

scholarly journals Is a safety guidewire needed for retrograde ureteroscopy?

2017 ◽  
Vol 63 (8) ◽  
pp. 717-721
Author(s):  
Wilson Rica Molina Junior ◽  
Rodrigo R. Pessoa ◽  
Rodrigo Donalísio da Silva ◽  
Diedra Gustafson ◽  
Leticia Nogueira ◽  
...  
Keyword(s):  
Randomized Trial ◽  
Primary Outcome ◽  
Urinary Calculi ◽  
Cochrane Library ◽  
Ureteral Stones ◽  
Ureteral Stricture ◽  
Review Of The Literature ◽  
Ureteral Stenosis ◽  
The Cochrane Library ◽  
Abnormal Anatomy

Summary Introduction: It is generally advised to have a safety guidewire (SGW) present during ureteroscopy (URS) to manage possible complications. However, it increases the strenght needed to insert and retract the endoscope during the procedure, and, currently, there is a lack of solid data supporting the need for SGW in all procedures. We reviewed the literature about SGW utilization during URS. Method: A review of the literature was conducted through April 2017 using PubMed, Ovid, and The Cochrane Library databases to identify relevant studies. The primary outcome was to report stone-free rates, feasibility, contraindications to and complications of performing intrarenal retrograde flexible and semi-rigid URS without the use of a SGW. Results: Six studies were identified and selected for this review, and overall they included 1,886 patients where either semi-rigid or flexible URS was performed without the use of a SGW for the treatment of urinary calculi disease. Only one study reported stone-free rates with or without SGW at 77.1 and 85.9%, respectively (p=0.001). None of the studies showed increased rates of complications in the absence of SGW and one of them showed more post-endoscopic ureteral stenosis whenever SGW was routinely used. All studies recommended utilization of SGW in complicated cases, such as ureteral stones associated with significant edema, ureteral stricture, abnormal anatomy or difficult visualization. Conclusion: Our review showed a lack of relevant data supporting the use of SGW during retrograde URS. A well-designed prospective randomized trial is in order.

scholarly journals Does early acne intervention provide more than just a reduction in the incidence of scars? A review of the literature

2021 ◽  
Vol 12 (4) ◽  
pp. 402-405
Author(s):  
Ayesha Vos
Keyword(s):  
Early Intervention ◽  
Cost Benefit ◽  
Cochrane Library ◽  
Published Data ◽  
Review Of The Literature ◽  
Primary Research ◽  
Acne Scars ◽  
Acne Treatment ◽  
The Cochrane Library ◽  
Relapse Rates

Background: It is well established that early intervention in acne treatment reduces the incidence of scars. The purpose of this paper was to identify if early intervention in acne management also provides a cost benefit to the patient, reduces relapse rates or lessens the requirement for the treatment of acne scars. Method: A systematic search of The Cochrane Library, MEDLINE and Cumulative Index to Nursing and Allied Health Literature (CINAHL) was performed independently by one reviewer using predefined criteria. Results: Seven articles were identified from the literature – one systematic review, one review article and five expert opinion articles. Although data supports early intervention in acne management, no articles identified whether a cost benefit was also provided, if there was a reduction in the relapse rates or if there was a decreased requirement for the treatment of acne scars. Conclusions: This review identifies an overall lack of published data regarding multiple outcomes for early intervention in acne and allows for the possible identification of areas where primary research would be beneficial.

Efficacy of compression stockings in preventing post-thrombotic syndrome in patients with deep venous thrombosis: a systematic review and metaanalysis

VASA ◽  
2016 ◽  
Vol 45 (2) ◽  
pp. 141-147 ◽  
Author(s):  
Jakob Martin Burgstaller ◽  
Johann Steurer ◽  
Ulrike Held ◽  
Beatrice Amann-Vesti
Keyword(s):  
Systematic Review ◽  
Venous Thrombosis ◽  
Deep Venous Thrombosis ◽  
Cochrane Library ◽  
Compression Stockings ◽  
Post Thrombotic Syndrome ◽  
Study Results ◽  
Preventive Efficacy ◽  
One Year ◽  
The Cochrane Library

Abstract. Background: Here, we update an earlier systematic review on the preventive efficacy of active compression stockings in patients with diagnosed proximal deep venous thrombosis (DVT) by including the results of recently published trials. The aims are to synthesize the results of the original studies, and to identify details to explain heterogeneous results. Methods: We searched the Cochrane Library, PubMed, Scopus, and Medline for original studies that compared the preventive efficacy of active compression stockings with placebo or no compression stockings in patients with diagnosed proximal DVT. Only randomized controlled trials (RCTs) were included. Results: Five eligible RCTs with a total of 1393 patients (sample sizes ranged from 47 to 803 patients) were included. In three RCTs, patients started to wear compression stockings, placebo stockings or no stockings within the first three weeks after the diagnosis of DVT. The results of two RCTs indicate a statistically significant reduction in post-thrombotic syndrome (PTS) of 50% or more after two or more years. The result of one RCT shows no preventive effect of compression stockings at all. Due to the heterogeneity of the study results, we refrained from pooling the results of the RCTs. In a further RCT, randomization to groups with and without compression stockings took place six months after the diagnosis of DVT, and in another RCT, only patients with the absence of PTS one year after the diagnosis of DVT were analyzed. One RCT revealed a significant reduction in symptoms, whereas another RCT failed to show any benefit of using compression stockings. Conclusions: At this time, it does not seem to be justifiable to entirely abandon the recommendations regarding compression stockings to prevent PTS in patients with DVT. There is evidence favoring compression stockings, but there is also evidence showing no benefit of compression stockings.

Barriers and facilitators to conducting research by early career psychiatrists: a literature review

2019 ◽  
Vol 2 (2) ◽  
pp. 135-154
Author(s):  
Katja Koelkebeck ◽  
Maja Pantovic Stefanovic ◽  
Dorota Frydecka ◽  
Claudia Palumbo ◽  
Olivier Andlauer ◽  
...  
Keyword(s):  
Research Participation ◽  
Early Career ◽  
Cochrane Library ◽  
Inclusion Criteria ◽  
Research Career ◽  
Hand Search ◽  
Electronic Search ◽  
Conducting Research ◽  
The Cochrane Library ◽  
To Receive

AbstractObjectivesTo understand and identify factors that promote and prevent research participation among early career psychiatrists (ECPs), in order to understand what would encourage more ECPs to pursue a research career.MethodsWe conducted an electronic search of databases (PubMed and the Cochrane library) using the keywords ‘doctors’, ‘trainees’, ‘residents’, ‘physicians’ and ‘psychiatric trainees’ as well as ‘research’ (MeSH) and ‘publishing’ (MeSH). This search was complemented by a secondary hand search.ResultsWe identified 524 articles, of which 16 fulfilled inclusion criteria for this review. The main barriers included lack of dedicated time for research, lack of mentoring and lack of funding. The main facilitators were opportunities to receive mentorship and access to research funding.ConclusionsAction is needed to counteract the lack of ECPs interested in a career in research. Specific programs encouraging ECPs to pursue research careers and having access to mentors could help increase the current numbers of researching clinicians in the field.

Intervención multi-componente en la prevención de la obesidad infantil como medida de salud pública

2017 ◽  
Vol 42 (2) ◽  
pp. 149-161
Author(s):  
Henry Cuevas Casa ◽  
Gabriela Aguinaga Romero ◽  
Fabricio González-Andrade
Keyword(s):  
Cochrane Library ◽  
Controlled Trials ◽  
The Cochrane Library

Objetivos: se propone identificar y revisar aquellas estrategias potenciales que incluyan un enfoque multifacético a la hora de hacer frente a la obesidad en niños escolarizados. De acuerdo a la evidencia más reciente, las intervenciones más efectivas para combatir la obesidad infantil son aquellas que involucranactividad física, educación nutricional y entornos de apoyo. Así, en esta revisión nos centramos en buscar dichas intervenciones, que además incluyan seguimientos a medio y largo plazo, monitoreo y evaluación, que son críticos para mantener una acción efectiva.Material y métodos: se incluyó una revisión de artículos científicos publicados en bases de datos especializadas como Pubmed (Medline), the Cochrane Library, The Cochrane Controlled Trials Register (CCTR), ScienceDirect, Scielo, La Biblioteca Cochrane Plus y la página web de la Organización Mundial de la Salud (http://www.who.int).Resultados: de 199 artículos potenciales, sólo 8 fueron incluidos en esta revisión. Los resultados mostraron que aquellas intervenciones multi-componente y de largo plazo tienen beneficios sobre IMC, actividad física y elecciones alimentarias. Sin embargo, pocos estudios mostraron cambios significativos sobrelos hábitos alimentarios generales y sobre la prevalencia de la obesidad. También, se observó que las intervenciones multicomponente que se llevaron a cabo tanto en países en desarrollo de Latinoamérica, como en países desarrollados tuvieron resultados similares.Conclusión: esta revisión demuestra que pueden ocurrir cambios sobre las medidas antropométricas, la actividad física y las elecciones alimentarias cuando se llevan a cabo intervenciones multicomponente en ambientes a nivel de la educación académica primaria, sin importar la localización geográfica, peromanteniendo similar metodología y materiales

BREAST CANCER SCREENING: CURRENT ACHIEVEMENTS, FUTURE PERSPECTIVES AND NEW TECHNOLOGIES

2019 ◽  
Vol 65 (5) ◽  
pp. 664-671
Author(s):  
Ilya Pyatnitskiy ◽  
O. Puchkova ◽  
Viktor Gombolevskiy ◽  
Lyudmila Nizovtsova ◽  
Natalya Vetsheva ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Screening ◽  
Breast Cancer Screening ◽  
New Technologies ◽  
Screening Program ◽  
Cochrane Library ◽  
Future Perspectives ◽  
Pubmed Database ◽  
The World ◽  
The Cochrane Library

The article presents a literature review of the PubMed database and the Cochrane library, aimed at analyzing the current situation and problems in the field of breast cancer screening in the world and Russia to form an idea of the key elements in organizing an effective screening program in the Russian healthcare system, as well as the possibilities of using new technologies when organizing such programs.

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