scholarly journals Effect of Ethanolic Extract of Propolis on Serum Biochemical Factors Level and Total Antioxidant Capacity in Adult Male Rats

2016 ◽  
Vol 22 (2) ◽  
pp. 145-150
Author(s):  
N Gheybi ◽  
R Bakhshibiniaz ◽  
R Taherkhani ◽  
H Jahani Hashemi ◽  
R Chegini ◽  
...  
Keyword(s):  
Antioxidant Capacity ◽  
Adult Male ◽  
Total Antioxidant Capacity ◽  
Ethanolic Extract ◽  
Male Rats ◽  
Total Antioxidant ◽  
Serum Biochemical ◽  
Ethanolic Extract Of Propolis

scholarly journals Protective Effect of Matricaria chamomilla Ethanolic Extract on Hippocampal Neuron Damage in Rats Exposed to Formaldehyde

2018 ◽  
Vol 2018 ◽  
pp. 1-10 ◽  
Author(s):  
Zahra Sayyar ◽  
Alireza Yazdinezhad ◽  
Maryam Hassan ◽  
Iraj Jafari Anarkooli
Keyword(s):  
Cell Death ◽  
Free Radicals ◽  
Antioxidant Capacity ◽  
Passive Avoidance ◽  
Avoidance Learning ◽  
Total Antioxidant Capacity ◽  
Ethanolic Extract ◽  
Passive Avoidance Learning ◽  
Matricaria Chamomilla ◽  
Total Antioxidant

Formaldehyde, as a frequently used compound in many applications, crosses the blood-brain barrier and leads to hippocampal cell death and memory impairment. This study investigates the effects of ethanolic extract of Matricaria chamomilla (MC) on passive avoidance learning induced by damaged hippocampal cells and evaluates the antioxidant traits of MC. The male Wistar rats were divided into six (6 in each) groups: control (10 mg/kg normal saline), 200 (200 mg/kg MC extract), 500 (500 mg/kg MC extract), F (10 mg/kg formaldehyde), F200 (10 mg/kg formaldehyde and 200 mg/kg MC extract), and F500 (10 mg/kg formaldehyde and 500 mg/kg MC extract). Shuttle box assay was used for evaluation of passive avoidance learning. The apoptosis rate of hippocampal tissue, malondialdehyde (MDA) free radicals, and total antioxidant capacity was evaluated to determine the positive effect of the ethanolic extract of MC. We found that the ethanolic extract of MC reduced the cell death, time spent in a dark room, and MDA free radicals in the hippocampus, leading to increased total antioxidant capacity in this region. In conclusion, the ethanolic extract of MC could ameliorate formaldehyde-induced memory damage through decreasing cell death and MDA activity of the hippocampal region and increasing total antioxidant capacity.

scholarly journals Simultaneous Effects of Exposure to Microwaves and Noise on Male Rats’ Sperm Parameters and Total Antioxidant Capacity

Health Scope ◽  
2013 ◽  
Vol 1 (4) ◽  
pp. 179-185 ◽  
Author(s):  
Masoud Ghanbari ◽  
Seyed Bagher Mortazavi ◽  
Ali Khavanin ◽  
Mozafar Khazaei
Keyword(s):  
Antioxidant Capacity ◽  
Total Antioxidant Capacity ◽  
Sperm Parameters ◽  
Male Rats ◽  
Total Antioxidant

scholarly journals Correlation between the antioxidant capacity of plasma and blood glucose level

2021 ◽  
pp. 108-115
Author(s):  
Eva Nurinda ◽  
Emelda ◽  
Nurul Kusumawardani
Keyword(s):  
Diabetes Mellitus ◽  
Blood Glucose ◽  
Antioxidant Capacity ◽  
Total Antioxidant Capacity ◽  
Ethanolic Extract ◽  
Tinospora Cordifolia ◽  
Total Blood ◽  
Glucose Levels ◽  
Blood Glucose Levels ◽  
Total Antioxidant

Introduction: Oxidative stress on tissues can cause diseases such as diabetes mellitus (DM). Aim: This study aimed to pharmacologically evaluate the decrease in blood glucose levels and its relationship with the total antioxidant capacity of the blood compared to glibenclamide. Method: An experimental study with completely randomised designs was carried out. Rats were induced with streptozotosin followed by ethanolic extract for ten days. Results: The One-Way Anova test, showed that the increase of the total antioxidant capacity of plasma treated with ethanolic extract of Tinospora cordifolia and Curcuma zanthorrhiza was comparable in the same amount to glibenclamide (p=0.345), (p=0.289). There was a relationship between total blood antioxidant capacity and blood glucose levels, this linear association was expressed with the following mathematical equation: y = 20,253 - 2,946x. Conclusion: The antioxidant content of Tinospora cordifolia, Curcuma zanthorrhiza, and Cinnamomum verum has the potential to control blood glucose in diabetes mellitus.

Effects of recombinant erythropoietin on serum total antioxidant capacity and HDL levels in male rats

2011 ◽  
Vol 44 (13) ◽  
pp. S176
Author(s):  
Khoyi Jaber Hashemzadeh ◽  
Nadereh Rashtchizadeh ◽  
Amir Ghorbanihagjo ◽  
Shabnam Hashemzadeh ◽  
Morteza Gharighoran
Keyword(s):  
Antioxidant Capacity ◽  
Total Antioxidant Capacity ◽  
Male Rats ◽  
Recombinant Erythropoietin ◽  
Total Antioxidant

scholarly journals Toxicological evaluation of the nicotine on CA1 and protective effects of curcuma longa: An experimental study

2019 ◽  
Vol 6 (9) ◽  
pp. 3368-3378
Author(s):  
Mohammad Reza Salahshoor ◽  
Shiva Roshankhah ◽  
Babak Arji Roudsari ◽  
Cyrus Jalili
Keyword(s):  
Antioxidant Capacity ◽  
Dendritic Spines ◽  
Total Antioxidant Capacity ◽  
Curcuma Longa ◽  
Male Rats ◽  
Control Group ◽  
Therapeutic Effects ◽  
Nitrite Oxide ◽  
Ca1 Region ◽  
Total Antioxidant

Introduction: Nicotine is the most important alkaloid compound in tobacco and is a major risk factor in the development of functional disorders of several organ systems. Some plants produce Curcuma longa (curcumin), which has antioxidant and neuro-protective properties. Methods: This study was designed to evaluate the therapeutic effects of curcumin against nicotine injury on the hippocampus CA1 region of rats. In this study, 48 male rats were randomly assigned to eight groups: Normal control (saline) group, Nicotine control group (0.5 mg/kg); Curcumin groups (10, 30, and 60 mg/kg) and Nicotine + Curcumin groups (10, 30, and 60 mg/kg). Treatments were administered intra-peritoneally daily for 28 days. Golgi staining technique investigated the number of dendritic spines. Cresyl violet staining method was used to determine the number of neurons in the hippocampal region CA1. Griess technique was assessed to determine serum nitrite oxide levels. Also, the ferric reducing/antioxidant power (FRAP) method was applied to determine the total antioxidant capacity. Results: Nicotine administration significantly increased the nitrite oxide level and decreased total antioxidant capacity. The number of neuronal dendritic spines, as well as neurons per se, also decreased, compared to the control group (p < 0.01). In all the members of the Curcumin and Nicotine + Curcumin groups, the number of neurons, neuronal dendritic spines and total antioxidant capacity increased significantly compared to the nicotine control group, while nitrite oxide level decreased significantly compared to the nicotine control group (p < 0.01). Conclusions: It seems that Curcumin administration improved hippocampal CA1 region injury in rats caused by Nicotine.  

scholarly journals Histological and Antioxidant Effect of different phone waves on the liver and kidney of male rats

2019 ◽  
Vol 10 (4) ◽  
pp. 3554-3559
Author(s):  
Nuha Sh. Ali ◽  
Haidar Alsaedi
Keyword(s):  
Antioxidant Capacity ◽  
Total Antioxidant Capacity ◽  
Cell Phone ◽  
The Body ◽  
Male Rats ◽  
Control Group ◽  
Sprague Dawley ◽  
Normal Ranges ◽  
Total Antioxidant ◽  
Liver And Kidney

There is tremendous concern about the potential harmful effects of cell phone microwaves. The results are contradictory. However, the effects of these waves on the body have been reported. In this study, the effect of cellular microwaves on sperm parameters and total antioxidant capacity in relation to the duration of exposure and frequency of these waves were studied. This experimental study was conducted on male Sprague Dawley rats (150-200 g). The animals were randomly assigned to three groups (n = 18). Group 1 Natural control rat were fed to standard laboratory feeding Animals for 14 days. Group 2 animals were exposed to cell phone receiver stimulated waves (915 MHz frequency) for 14 days, and Group 3 animals were exposed to simulated waves of a cell phone antenna (950 MHz frequency) for 14 days. The results indicated that the total antioxidant capacity in all exposure groups decreased significantly compared with the control group (P <0.05). Increased exposure time within two weeks caused a statistically significant decrease in sperm motility and mobility (P <0.05).Effect of phone waves on liver and kidney of male Sprague Dawley rat. The study of pathological anatomy revealed a clear and appropriate deviation. These results found blood enzymes such as amino-aspartase transferase (AST), amino amines (ALT), and creatinine levels. The results showed no significant changes in both liver and kidney physiological functions. Malondialdehyde level (MDA) and total antioxidant contents were performed. The level of glutathione (GST), superoxide dismutase (SOD) was in normal ranges. Exposure to cell phone waves can reduce sperm movement and mobility in rats. These waves can also reduce the total antioxidant capacity in rats and lead to oxidative stress.

scholarly journals Effects Of The Ethanolic Extract Of Rosa Canina On Some Serum Biochemical Factors In Diabetic Adult Male Rats

2015 ◽  
Vol 13 (2) ◽  
pp. 143-148
Author(s):  
S. Khojasteh ◽  
E. Basirat ◽  
F. Sheikhzadeh ◽  
S. Ozy ◽  
G. Dehghan ◽  
...  
Keyword(s):  
Adult Male ◽  
Ethanolic Extract ◽  
Male Rats ◽  
Rosa Canina ◽  
Serum Biochemical

scholarly journals Simultaneous Effects of Exposure to Microwaves and Noise on Male Rats’ Sperm Parameters and Total Antioxidant Capacity

Health Scope ◽  
2013 ◽  
Vol 1 (4) ◽  
Author(s):  
Masoud Ghanbari ◽  
Seyed Bagher Mortazavi ◽  
Ali Khavanin ◽  
Mozafar Khazaei
Keyword(s):  
Antioxidant Capacity ◽  
Total Antioxidant Capacity ◽  
Sperm Parameters ◽  
Male Rats ◽  
Total Antioxidant

Trans-resveratrol supplement lowers lipid peroxidation responses of exercise in male Wistar rats

2020 ◽  
pp. 1-6 ◽  
Author(s):  
Masoud Nasiri ◽  
Saja Ahmadizad ◽  
Mehdi Hedayati ◽  
Tayebe Zarekar ◽  
Mehdi Seydyousefi ◽  
...  
Keyword(s):  
Lipid Peroxidation ◽  
Antioxidant Capacity ◽  
Total Antioxidant Capacity ◽  
Wistar Rats ◽  
Enzymatic Antioxidants ◽  
Acute Response ◽  
Total Antioxidant ◽  
Male Wistar Rats ◽  
Exercise Induced ◽  
And Control

Abstract. Physical exercise increases free radicals production; antioxidant supplementation may improve the muscle fiber’s ability to scavenge ROS and protect muscles against exercise-induced oxidative damage. This study was designed to examine the effects of all-trans resveratrol supplementation as an antioxidant to mediate anti-oxidation and lipid per-oxidation responses to exercise in male Wistar rats. Sixty-four male Wistar rats were randomly divided into four equal number (n = 16) including training + supplement (TS), training (T), supplement (S) and control (C) group. The rats in TS and S groups received a dose of 10 mg/kg resveratrol per day via gavage. The training groups ran on a rodent treadmill 5 times per week at the speed of 10 m/min for 10 min; the speed gradually increased to 30 m/min for 60 minutes at the end of 12th week. The acute phase of exercise protocol included a speed of 25 m/min set to an inclination of 10° to the exhaustion point. Superoxide dismutase (SOD), glutathione peroxidase (GPx), catalase (CAT) activity, non-enzymatic antioxidants bilirubin, uric acid, lipid peroxidation levels (MDA) and the total antioxidant capacity (TAC) were measured after the exercise termination. The data were analyzed by using one-way ANOVA. The result showed that endurance training caused a significant increase in MDA level [4.5 ± 0.75 (C group) vs. 5.9 ± 0.41 nmol/l (T group)] whereas it decreased the total antioxidant capacity [8.5 ± 1.35 (C group) vs. 7.1 ± 0.55 mmol/l (T group)] (p = 0.001). In addition, GPx and CAT decreased but not significantly (p > 0.05). The training and t-resveratrol supplementation had no significant effect on the acute response of all variables except MDA [4.3 ± 1.4 (C group) vs. 4.0 ± 0.90 nmol/l (TS group)] (p = 0.001) and TAC [8.5 ± 0.90 (C group) vs. 6.6 ± 0.80 mmol/l (TS group)] (p = 0.004). It was concluded that resveratrol supplementation may prevent exercise-induced oxidative stress by preventing lipid peroxidation.

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