Major Depressive Disorder and Depressive Symptomatology as Predictors of Husband to Wife Physical Aggression

This study investigated the association between a husband’s depressive symptomatology and the frequency of physical aggression toward his wife, as well as a husband’s Major Depressive Disorder (MDD) and the frequency of physical aggression toward his wife. We assessed physically aggressive men who volunteered for treatment with their wives (N = 89). Almost one third had moderate levels of depressive symptomatology (Beck Depression Inventory [BDI ≥ 14]), but only 11% met criteria for MDD (based on a structured interview [SCID]). Although the rate of MDD was not absolutely high, it was higher than that reported in a community sample (i.e., 3%). A significant relationship between increased depressive symptomatology and frequency of physical aggression was found, but the association was most likely accounted for by self-reported anger. Related contextual factors including marital discord and psychological aggression are addressed. Theoretical and treatment implications are discussed, including the severity of the treatment population (volunteer vs. court mandated), and severity of the depression (symptomatology vs. clinical diagnosis).

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A simpler definition of major depressive disorder

Psychological Medicine ◽

10.1017/s0033291709990572 ◽

2009 ◽

Vol 40 (3) ◽

pp. 451-457 ◽

Cited By ~ 26

Author(s):

M. Zimmerman ◽

J. N. Galione ◽

I. Chelminski ◽

J. B. McGlinchey ◽

D. Young ◽

...

Keyword(s):

Major Depressive Disorder ◽

Depressive Disorder ◽

Somatic Symptoms ◽

Structured Interview ◽

Major Depressive ◽

Medically Ill ◽

Treatment Providers ◽

Dsm Iv ◽

Definition Of ◽

High Level

BackgroundThe DSM-IV symptom criteria for major depressive disorder (MDD) are somewhat lengthy, with many studies showing that treatment providers have difficulty recalling all nine symptoms. Moreover, the criteria include somatic symptoms that are difficult to apply in patients with medical illnesses. In a previous report, we developed a briefer definition of MDD that was composed of the mood and cognitive symptoms of the DSM-IV criteria, and found high levels of agreement between the simplified and full DSM-IV definitions. The goal of the present study was to replicate these findings in another large sample of psychiatric out-patients and to extend the findings to other patient samples.MethodWe interviewed 1100 psychiatric out-patients and 210 pathological gamblers presenting for treatment and 1200 candidates for bariatric surgery. All patients were interviewed by a diagnostic rater who administered a semi-structured interview. We inquired about all symptoms of depression for all patients.ResultsIn all three samples high levels of agreement were found between the DSM-IV and the simpler definition of MDD. Summing across all 2510 patients, the level of agreement between the two definitions was 95.5% and the κ coefficient was 0.87.ConclusionsAfter eliminating the four somatic criteria from the DSM-IV definition of MDD, a high level of concordance was found between this simpler definition and the original DSM-IV classification. This new definition offers two advantages over the current DSM-IV definition – it is briefer and it is easier to apply with medically ill patients because it is free of somatic symptoms.

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Relationship between spirituality and suicidal ideations among patients with major depressive disorder

Journal of Nursing Education and Practice ◽

10.5430/jnep.v9n4p113 ◽

2018 ◽

Vol 9 (4) ◽

pp. 113

Author(s):

Souzan Abd El-Menem Abd El-Ghafar Harfus ◽

Amal Awad Abd El-Nabi Moussa ◽

Samar Mabrook El-Nehrawy

Keyword(s):

Major Depressive Disorder ◽

Depressive Disorder ◽

Negative Correlation ◽

Meaning In Life ◽

Significant Negative Correlation ◽

Structured Interview ◽

Major Depressive ◽

Correlational Design ◽

Psychiatric Department ◽

The Relationship

Background and objective: Suicide still constitutes to be a critical and risky issue requiring preventive strategies. There is evidence to suggest that spirituality is vital to the process of discovering meaning in life and plays an important role in dealing with suicidal desire. The aim of this study was to investigate the relationship between spirituality and suicidal ideations among patients with major depressive disorder.Methods: Design and participants: A descriptive correlational design was utilized in the current study. A purposive sample of 181 patients with major depressive disorder was recruited. Setting: The study was conducted at inpatient psychiatric department of Tanta University and Neurology, Psychiatry, and Neuro-Surgery Center. Both hospitals are under the supervision and direction of the ministry of higher education. Tools: Four tools were used to collect data; socio-demographic and clinical characteristics structured interview schedule, Beck Depression Inventory, Daily Spiritual Experience Scale, and Scale for Suicide Ideation.Results: The current study indicated a statistical significant negative correlation between depression and spirituality. Also, a statistical significant negative correlation was found between spirituality and one subscale of suicide which is active suicide desire subscale. On the other side, there was a statistical significant positive correlation between depression and total score of suicide.Conclusions: Higher levels of spirituality may help buffer risk of active suicide desire and promote protective effect against depression. Recommendation: interventions that aim at increasing spiritual involvement and practice may be beneficial in reducing depressive symptoms and suicide desire.

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The effectiveness of intravenous ketamine in adults with treatment-resistant major depressive disorder and bipolar disorder presenting with prominent anxiety: Results from the Canadian Rapid Treatment Center of Excellence

Journal of Psychopharmacology ◽

10.1177/0269881120954048 ◽

2020 ◽

pp. 026988112095404

Author(s):

Roger S McIntyre ◽

Nelson B Rodrigues ◽

Orly Lipsitz ◽

Flora Nasri ◽

Hartej Gill ◽

...

Keyword(s):

Bipolar Disorder ◽

Major Depressive Disorder ◽

Depressive Disorder ◽

Depressive Symptomatology ◽

Rapid Onset ◽

Anxiety Symptoms ◽

Self Report ◽

Treatment Center ◽

Treatment Resistant ◽

Major Depressive

Background: Individuals meeting criteria for treatment-resistant depression (TRD) are differentially affected by high levels of anxiety symptoms. Aims: There is a need to identify the efficacy of novel rapid-onset treatments in adults with mood disorders and comorbid anxious-distress. Methods: This study included patients with treatment-resistant major depressive disorder (MDD) or bipolar disorder (BD) who were receiving intravenous (IV) ketamine treatment at a community-based clinic.Anxious-distress was proxied using items from the Quick Inventory of Depressive Symptomatology–Self Report 16-item (QIDS-SR16) and Generalized Anxiety Disorder 7-item (GAD7) scales. The difference in QIDS-SR16 total score, QIDS-SR16 suicidal ideation (SI) item and GAD7 score were analyzed between groups. Results: A total of 209 adults with MDD ( n = 177) and BD ( n = 26) were included in this analysis. From this sample, 94 patients (mean = 45 ± 13.9 years) met the criteria for anxious-distress. Individuals meeting the criteria for anxious-distress exhibited a significantly greater reduction in QIDS-SR16 total score following four infusions ( p = 0.02) when compared with patients not meeting the anxious-distress criteria. Both anxious-distressed and low-anxiety patients exhibited a significant reduction in SI ( p < 0.0001) following four infusions.Finally, there was a significantly greater reduction in anxiety symptoms in the anxious-distress group compared with the non–anxious distress group following three ( p = 0.02) and four infusions ( p < 0.001). Conclusion: Patients with TRD and prominent anxiety receiving IV ketamine exhibited a significant reduction in depressive, SI and anxiety symptoms.

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The selective orexin-2 receptor antagonist seltorexant improves sleep: An exploratory double-blind, placebo controlled, crossover study in antidepressant-treated major depressive disorder patients with persistent insomnia

Journal of Psychopharmacology ◽

10.1177/0269881118822258 ◽

2019 ◽

Vol 33 (2) ◽

pp. 202-209 ◽

Cited By ~ 9

Author(s):

Sander Brooks ◽

Gabriël E Jacobs ◽

Peter de Boer ◽

Justine M Kent ◽

Luc Van Nueten ◽

...

Keyword(s):

Major Depressive Disorder ◽

Depressive Disorder ◽

Depressive Symptomatology ◽

Total Sleep Time ◽

Sleep Time ◽

Sleep Efficiency ◽

Least Square ◽

Self Report ◽

Major Depressive ◽

Double Blind

Background: Insomnia is common in patients with major depressive disorder. Although antidepressants improve mood, insomnia often persists as a result of physiological hyperarousal. The orexin-2 receptor is increasingly being recognized as a new target for the treatment of persistent insomnia in major depressive disorder . Aim: This exploratory study investigated the effects of seltorexant on objective sleep parameters and subjective depressive symptoms in antidepressant treated major depressive disorder patients with persistent insomnia. Methods: Twenty male and female patients received a single dose of 10, 20, 40 mg seltorexant and placebo with a washout period of seven days in a double-blind four-way crossover study. Effects on latency to persistent sleep, total sleep time and sleep efficiency were assessed with polysomnography. Subjective changes in mood were explored by the Quick Inventory of Depressive Symptomatology Self-Report. Safety was recorded and suicidal ideation and behavior were assessed with the Columbia Suicide Severity Rating Scale. Results: Latency to persistent sleep was significantly shorter for all doses of seltorexant compared to placebo. Placebo least square mean was 61.05 min with least square mean ratios treatment/placebo (80% confidence interval) of 0.32 (0.24–0.44), 0.15 (0.11–0.2) and 0.17 (0.12–0.23) 19.69, 9.2, 10.15 for 10, 20 and 40 mg seltorexant respectively, (all p<0.001). Total sleep time was significantly longer for all doses of seltorexant compared to placebo. Sleep efficiency was significantly improved. The Quick Inventory of Depressive Symptomatology Self-Report demonstrated a trend to mood-improvement for the 40 mg group. Conclusions: Seltorexant showed a statistically significant, dose-dependent decrease in latency to persistent sleep, and increase in total sleep time and sleep efficiency combined with a tendency toward subjectively improved mood.

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The Quick Inventory of Depressive Symptomatology-Self-report: a psychometric evaluation in patients with asthma and major depressive disorder

Annals of Allergy Asthma & Immunology ◽

10.1016/s1081-1206(10)60467-x ◽

2008 ◽

Vol 100 (5) ◽

pp. 433-438 ◽

Cited By ~ 15

Author(s):

E. Sherwood Brown ◽

Michelle Murray ◽

Thomas J. Carmody ◽

Beth D. Kennard ◽

Carroll W. Hughes ◽

...

Keyword(s):

Major Depressive Disorder ◽

Depressive Disorder ◽

Depressive Symptomatology ◽

Psychometric Evaluation ◽

Self Report ◽

Major Depressive

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Network Analysis of Depressive Symptomatology in Elderly Patients with Major Depressive Disorder

Current Psychiatry Research and Reviews ◽

10.2174/2666082217666210203144519 ◽

2021 ◽

Vol 17 ◽

Author(s):

Seon-Cheol Park

Keyword(s):

Major Depressive Disorder ◽

Depressive Symptoms ◽

Network Analysis ◽

Depressive Disorder ◽

Elderly Patients ◽

Rating Scale ◽

Depressive Symptomatology ◽

Depressive Mood ◽

Major Depressive ◽

Using Data

Background: A novel psychopathological approach is the application of network analysis, as it is proposed that symptoms and their interconnections constitute a disease itself, rather than simply being components or outcome factors of disease. Objective: Using data from the Clinical Research Center for Depression (CRESCEND) Study, this study examined depressive symptoms in elderly patients with major depressive disorder using a network analysis approach. Methods: Among 135 elderly patients with major depressive disorder who were recruited from the CRESCEND study, we created a network based on individual items from the Hamilton Depression Rating Scale (HAMD), with the nodes being each item (symptom) and the edges being the strength of the association between the items (interconnection). By calculating measures of centrality of each of the nodes, we were able to determine which depressive symptoms were most central (influential) in the network. Results: The insight item was completely unconnected with other items and it was excluded in terms of network analysis. Thus, a network analysis of the 16 HAMD items estimated that the anxiety psychic item was the most central domain, followed by insomnia (middle of the night), depressive mood, and insomnia (early hours of the morning) items. On the contrary, the retardation item was the most poorly interconnected with the network. Conclusion: We suggest that our study makes a significant contribution to the literature because we have found that anxiety, depressed mood, and insomnia are most central to the network, indicating that they are the most influential symptoms in major depression in elderly individuals.

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Well-being and life satisfaction in generalized anxiety disorder: comparison to major depressive disorder in a community sample

Journal of Affective Disorders ◽

10.1016/s0165-0327(02)00457-3 ◽

2004 ◽

Vol 79 (1-3) ◽

pp. 161-166 ◽

Cited By ~ 66

Author(s):

Murray B Stein ◽

Richard G Heimberg

Keyword(s):

Life Satisfaction ◽

Major Depressive Disorder ◽

Anxiety Disorder ◽

Depressive Disorder ◽

Generalized Anxiety Disorder ◽

Community Sample ◽

Well Being ◽

Generalized Anxiety ◽

Major Depressive

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The Quick Inventory of Depressive Symptomatology (Clinician and Self-Report Versions) in Patients With Bipolar Disorder

CNS Spectrums ◽

10.1017/s1092852900029230 ◽

2010 ◽

Vol 15 (6) ◽

pp. 367-373 ◽

Cited By ~ 10

Author(s):

Ira H. Bernstein ◽

A. John Rush ◽

Trisha Suppes ◽

Yakasushi Kyotoku ◽

Diane Warden

Keyword(s):

Bipolar Disorder ◽

Major Depressive Disorder ◽

Depressive Symptoms ◽

Depressive Disorder ◽

Depressive Symptomatology ◽

Self Report ◽

General Interest ◽

Major Depressive ◽

Sad Mood ◽

Illness Phase

ABSTRACTIntroduction: The clinical and self-report versions of the Quick Inventory of Depressive Symptomatology (QIDS-C16 and QIDS-SR16) have been well studied in patients with major depressive disorder and in one recent study using patients with bipolar disorder. This article examines these measures in a second sample of 141 outpatients with bipolar disorder in different phases of the illness.Methods: At baseline, 61 patients were depressed and 30 were euthymic; at exit, 50 were depressed and 52 were euthymic. The remaining patients (at baseline or exit) were in either a manic or mixed phase and were pooled for statistical reasons.Results: Similar results were found for the QIDS-C16 and QIDS-SR16. Scores were reasonably reliable to the extent that variability within groups permitted. As expected, euthymic patients showed less depressive symptomatology than depressed patients. Sad mood and general interest were tne most discriminating symptoms between depressed and euthymic phases. Changes in illness phase (baseline to exit) were associated with substantial changes in scores. The relation of individual depressive symptoms to the overall level of depression was consistent across phases.Conclusion: Both the QIDS-SR16 and QIDS-C16 are suitable measures of depressive symptoms in patients with bipolar disorder.

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