scholarly journals Assessment of Asthma Control and Severity among Children According to Global Initiative for Asthma Guidelines in Sulaimani City-Iraq

2016 ◽  
Vol 12 (3) ◽  
pp. 160
Author(s):  
Adnan M. H. Hamawandi ◽  
Kosar M Ali ◽  
Ali Z. Naji
Keyword(s):  
Asthma Control ◽  
Objective Assessment ◽  
Asthma Management ◽  
Persistent Asthma ◽  
Cross Sectional ◽  
Asthmatic Children ◽  
Global Initiative For Asthma ◽  
Severe Persistent Asthma ◽  
Global Initiative ◽  
Gina Guidelines

Background: Asthma is a common and potentially serious chronic disease that imposes a substantial burden on patients, their families and the community. Objective: Assessment of the level of asthma control and severity in asthmatic children in Sulaimani city according to the global initiative for asthma (GINA) guidelines. Methods: A cross-sectional study of 82 patients who are known cases of asthma, aged 5 – 15 years , from 1st of March 2014 to 1st of August 2014. Results: Out of 82 patients in our study, 20.8%were classified as having intermittent asthma all of them have well controlled asthma, 42.7% of those classified as having mild persistent asthma 65.7% of them have well controlled asthma, 26.8% of those classified as having moderate persistent asthma 54.5% of them have partly controlled asthma, and 9.8%of those classified as having severe persistent asthma the majority of them 87.5% have uncontrolled asthma and none of them reached to the controlled asthma level according to GINA guidelines. Regarding the peak expiratory flow (PFT) we notice that 58.8% of asthmatic children who were classified as having intermittent severity, their PEF measurements ranged between 160- 250 l/min while those with severe persistent asthma 75% of them have readings between 50-150 l/min. Conclusion: Current levels of asthma control in the Sulaimani city fall far short of the goals specified in the GINA guidelines for asthma management. Also there is a strong correlation between PEF measurements and the level of asthma severity,

scholarly journals Assessment of asthma control and lung function in asthmatic children in Sokoto, North Western Nigeria

2021 ◽  
Vol 0 ◽  
pp. 1-6
Author(s):  
Fatima Abubakar Ishaq ◽  
Bilkisu Ilah Garba ◽  
Nma Mohammad Jiya ◽  
Ahmed Hamidu
Keyword(s):  
Lung Function ◽  
Asthma Control ◽  
Cross Sectional Study ◽  
University Teaching ◽  
Cross Sectional ◽  
Asthmatic Children ◽  
Children With Asthma ◽  
Global Initiative ◽  
Gina Guidelines ◽  
Study Participants

Objectives: This study aimed at assessing asthma control using Global Initiative for Asthma (GINA) asthma assessment, and determining its relationship with lung function parameters among asthmatic children in Usmanu Danfodiyo University Teaching hospital, Sokoto. Materials and Methods: This was a cross-sectional study among 60 children with asthma diagnosed based on GINA guidelines. It was conducted over a period of 4 months. The GINA asthma control assessment was administered to assess asthma control. Lung function was done using a portable spirometer. Results: Males accounted for 58.3% of the study population with M: F of 1.4:1 and median age of 9.47 years, with majority from urban domicile (91.7%). Well-controlled asthma accounted for 50.0% while 35.0% had partly controlled asthma and 15.0% had poorly controlled asthma. The median FEV1/FVC among the study participants was 0.856 (IQR: 0.170). There was no relationship between asthma control and LF parameters (FEV1: r = 0.044, P = 0.736, FVC: r = 0.010, P = 0.941, FEV1/FVC: r = 0.122, P = 0.352, and PEFR: r = 0.015, P = 0.911). Conclusion: Majority of the study participants had well-controlled asthma and no relationship was found between asthma control and lung function. Thus, serial monitoring of LF in addition to uniformly agreed standardized assessment of asthma control is required to objectively evaluate asthma control in children.

scholarly journals Is there an association between the value of forced expiratory volume in the 1st second, the Asthma Control Test and a Control Framework by Global Initiative for asthma in asthmatic children and adolescents treated with inhaled corticosteroids?

2019 ◽  
Vol 29 (3) ◽  
pp. 346-353
Author(s):  
Karla Delevedove Taglia-Ferre ◽  
Sandra Lisboa ◽  
Luanda Dias da S. Salviano ◽  
Ana Carolina Carioca da Costa ◽  
Shandra Lisboa Monteiro ◽  
...  
Keyword(s):  
Children And Adolescents ◽  
Asthma Control ◽  
Control Method ◽  
Inhaled Corticosteroids ◽  
Forced Expiratory Volume ◽  
Control Test ◽  
Asthma Control Test ◽  
Asthmatic Children ◽  
Global Initiative For Asthma ◽  
Global Initiative

Objective: Evaluate the presence of association between the classification of the level of asthma control, using the method proposed by the Global Initiative for Asthma (GINA), the Asthma Control Test (ACT)/Childhood-ACT and the forced expiratory volume in the 1st second (FEV1), in asthmatic children and adolescents treated with inhaled corticosteroids, followed up at the National Institute of Women's, Children's and Adolescents' Health FernandesFigueira of the Oswaldo Cruz Foundation (IFF / FIOCRUZ). Method: A cross-sectional study was carried out with a review of the medical records of all children between 7 and 17 years of age followed up at the Asthma Outpatient Clinic and referred to the Respiratory Insertion Test (PFR) sector between March 2013 and September 2014. In the same day were applied the C-ACT/ACT questionnaires, an asthma control method proposed by the GINA and the FEV1 value in a spirometrictest. Results: From the total number of records evaluated (72), 16 children were excluded because they did not meet the required criteria for performing spirometry. The sample studied (56 children) was predominantly male (58.9%) and median age was 12 (7-17) years. It was observed an association between FEV1 and GINA values ??(p <0.01). Conclusion: The results found in this study indicate that FEV1 measurement is a useful component among the instruments for assessing clinical control of asthma by GINA.

scholarly journals Still Fighting for Breath: a patient survey of the challenges and impact of severe asthma

2018 ◽  
Vol 4 (4) ◽  
pp. 00076-2018 ◽  
Author(s):  
Paraskevi Katsaounou ◽  
Mikaela Odemyr ◽  
Otto Spranger ◽  
Michael E. Hyland ◽  
Claus Kroegel ◽  
...  
Keyword(s):  
Severe Asthma ◽  
Online Survey ◽  
Persistent Asthma ◽  
Patient Survey ◽  
Management Support ◽  
Daily Lives ◽  
Global Initiative For Asthma ◽  
Severe Persistent Asthma ◽  
Global Initiative ◽  
The Impact

We conducted a large global survey, Still Fighting for Breath, in patients with severe persistent asthma, 10 years after the Fighting for Breath survey to assess the impact of disease on patients' lives and to determine if control and management have changed in recent years.Data were collected from 1333 adults (aged >18 years) and caregivers of children (aged 6–17 years) with severe persistent asthma from nine countries through an online survey conducted in 2016 by GfK.A decade after the first survey, our results showed that the impact of severe asthma has not changed significantly and a high proportion of patients with severe asthma remain inadequately controlled. A large discrepancy was observed between the proportion of patients who perceived their asthma to be well controlled (42%) and the proportion of patients who reported to be well controlled as per the Global Initiative for Asthma (GINA) assessment (6%). Although most patients perceived their asthma to be controlled, many experienced frequent symptoms that affected their daily lives.Thus, there is a need for improved management (support and strategies) of patients with severe persistent asthma and improved coordination of efforts that would enable these patients to achieve better disease control.

scholarly journals Evaluation of inflammation by level of Interleukin 4 in exhaled breath condensate in patients affected by bronchial asthma treated according to GINA guidelines

2011 ◽  
Vol 1 (1) ◽  
pp. 11
Author(s):  
Giuseppe Valerio ◽  
Pierluigi Bracciale ◽  
Fabio Valerio
Keyword(s):  
Asthma Control ◽  
Bronchial Asthma ◽  
Persistent Asthma ◽  
Bronchial Reactivity ◽  
Airways Obstruction ◽  
Severe Persistent Asthma ◽  
Gina Guidelines ◽  
One Year ◽  
Breath Condensate ◽  
Airways Inflammation

GINA guidelines suggest that optimal asthma control can be gained by regular monitoring of symptoms, rescue medication use, airways obstruction and variability upon time of airways flows. Our aim was to check if therapy according to GINA rules is able to lower airways inflammation, measured by the level of IL4 in expired breath condensate (EBC). One hundred patients affected by bronchial asthma in different levels were recruited as they come to the ambulatory ward. They were cured according to GINA guidelines for one year, using inhaled fluthicasone as inhaled steroid. Symptoms were monitored by asthma control test score (ACT), airways obstruction by FEV1, bronchial reactivity by PD20, airways inflammation by IL4 in EBC. ACT showed complete control in the first three GINA levels, improving incompletely in the GINA level 4 (from 20&plusmn;2 to 21&plusmn;12; from 17&plusmn;2 to 22&plusmn;2; from 14&plusmn;4 to 18&plusmn;3; from 10&plusmn;3 to 14&plusmn;3 units respectively in the first to fourth levels of asthma). FEV1 improved, but both baseline and after therapy levels were worst in severe persistent asthma (from 96&plusmn;5 to 96&plusmn;4; from 92&plusmn;6 to 93&plusmn;3; from 74&plusmn;6 to 83&plusmn;8; from 45&plusmn;10 to 60&plusmn;5% of normal standards respectively from the 1st to 4th level). PD20 and IL4 were fairly normalized by therapy in the s and third levels, improved in the last one (PD20 from 437&plusmn;329 to 460&plusmn;269, from 364&plusmn;308 to &gt;1600, from 436&plusmn;252 to 890&plusmn;220; from 45&plusmn;25 to 60&plusmn;40 mcg respectively, IL4 in EBC from 60&plusmn;6 to 40&plusmn;12, from 65&plusmn;10 to 41&plusmn;9, from 72&plusmn;8 to 45&plusmn;6, from 78&plusmn;20 to 52&plusmn;5 respectively). IL4 and PD20 were significantly related. Experimental data allowed the assessment of the correlation of inflammation with bronchial reactivity and the relevance of addressing therapy upon IL4. Severe persistent asthma behave as a different entity with worst baseline inflammation, partially refractory asthma and persistent inflammation, needing specific immunologic weapons. Bronchial inflammation was fairly reduced but not normalized after one year of therapy.

scholarly journals The Quality of Life on Asthmatic Adolescent and Its Correlation with the Severity and Control of Asthma

2020 ◽  
Vol 8 (1) ◽  
Author(s):  
Lisa Adhia Garina ◽  
Muhammad Ridho Grahadinta ◽  
Ferry Achmad Firdaus Mansoer ◽  
Intan Puspitasari
Keyword(s):  
Quality Of Life ◽  
Asthma Control ◽  
Asthma Severity ◽  
Control Test ◽  
Asthma Control Test ◽  
Cross Sectional ◽  
Spearman's Rho ◽  
Global Initiative For Asthma ◽  
Global Initiative

Asthma is considered a global health problem that, if not managed properly, can reduce the sufferers' quality of life. The purpose of the study was to evaluate the quality of life from the perspectives of asthma severity and the asthma control level. A cross-sectional study was conducted from February to June 2018 on asthmatic adolescents aged 12–14 years old in two public junior high schools in Bandung city, Indonesia. The diagnosis, history of asthma,  severity, and asthma control were established based on the National Asthma Guidelines from the Indonesian Pediatric Society, Global Initiative for Asthma (GINA), asthma control test (ACT), and ISAAC questionnaire. Statistical analysis performed using SPSS v.20 with Spearman's rho to determine the significance. The gender distribution of the 98 subjects was almost similar with slightly more girls (51%). The median age was 13±1 years with average ACT, FVC, and PAQLQ(S) total scores of 20±4, 78±16%, and 5.3±1.3, respectively. The domain scores for symptoms, activity limitations, and emotional function were 4.9±1.4, 5.0±1.3, and 5.7±1.1, respectively. There are correlations between the total  PAQLQ(S) score and asthma severity (p<0.001, r=−0.5) and the level of asthma control (p<0.001, r=0.6). In summary, the quality of life has a relationship with asthma severity and the level of asthma control. Asthma management should not only focus on medication but also ways to maintain a good quality of life. KUALITAS HIDUP REMAJA ASMA DAN HUBUNGANNYA DENGAN KEKERAPAN GEJALA DAN DERAJAT KENDALI ASMAAsma masih menjadi masalah kesehatan penting yang jika tidak ditangani baik, asma dapat menurunkan kualitas hidup anak. Tujuan penelitian ini menilai kualitas hidup dan hubungannya dengan kekerapan gejala dan derajat kendali asma. Penelitian cross-sectional ini dilaksanakan dari bulan Februari hingga Juni 2018 pada remaja asma berusia 12–14 tahun di dua SMPN di Kota Bandung, Indonesia. Diagnosis, riwayat asma, kekerapan gejala, dan derajat kendali asma berdasar atas Pedoman Nasional Asma Anak Ikatan Dokter Anak Indonesia, Global Initiative for Asthma (GINA), asthma control test (ACT), dan kuesioner dari ISAAC. Analisis statistik menggunakan SPSS v.20 dengan uji Spearman’s rho untuk menentukan signifikansi. Distribusi gender dari 98 subjek penelitian hampir sama dengan sedikit lebih banyak perempuan (51%). Usia rerata subjek 13±1 tahun dengan skor rerata ACT, FVC, PAQLQ(S) masing-masing 20±4, 78±16%, dan 5,3±1,3. Skor domain gejala, keterbatasan beraktivitas, dan fungsi emosi masing-masing 4,9±1,4; 5,0±1,3; dan 5,7±1,1. Terdapat hubungan skor total PAQLQ(S) dengan kekerapan gejala (p<0,001; r=−0,5) dan dengan derajat kendali asma (p<0,001; r=0,6). Simpulan, kualitas hidup berhubungan dengan kekerapan gejala dan derajat kendali asma. Pengelolaan asma sebaiknya tidak hanya memperhatikan pengobatan, tetapi juga menjaga kualitas hidup yang baik.

scholarly journals National Asthma Education and Prevention Program 2020 Guidelines: What’s Important for Primary Care

2021 ◽  
Vol 70 (6 Supplement) ◽  
Author(s):  
Murphy
Keyword(s):  
Primary Care ◽  
Prevention Program ◽  
Expert Panel ◽  
Asthma Management ◽  
Persistent Asthma ◽  
Asthma Severity ◽  
Asthma Education ◽  
Global Initiative For Asthma ◽  
Primary Care Clinicians ◽  
Global Initiative

KEY TAKEAWAYS • The 2020 Focused Updates to the Asthma Management Guidelines: A Report from the National Asthma Education and Prevention Program Coordinating Committee Expert Panel Working Group provides updated recommendations for 6 topics related to the management of individuals with asthma. • The classification of asthma severity and asthma control, as well as the concept of utilizing a stepwise approach to pharmacologic treatment, were not updated from the Expert Panel Report 3, released in 2007. • However, important updates in preferred therapies for intermittent and persistent asthma at treatment steps 1 through 5 were suggested. • Recommendations regarding biologic therapy were not included in the 2020 update, as only evidence and US Food and Drug Administration approvals through October 2018 were considered. • The most recent 2021 Global Initiative for Asthma guidelines are not included in this review but can be used in a complementary manner to assist primary care clinicians to optimize decisions regarding the care of patients with asthma.

scholarly journals Higher Omega-3 Index Is Associated with Better Asthma Control and Lower Medication Dose: A Cross-Sectional Study

Nutrients ◽  
2019 ◽  
Vol 12 (1) ◽  
pp. 74 ◽  
Author(s):  
Isobel Stoodley ◽  
Manohar Garg ◽  
Hayley Scott ◽  
Lesley Macdonald-Wicks ◽  
Bronwyn Berthon ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Asthma Control ◽  
Inhaled Corticosteroids ◽  
Asthma Management ◽  
Airway Disease ◽  
Cross Sectional Study ◽  
Erythrocyte Membranes ◽  
Omega 3 ◽  
Asthma Control Questionnaire ◽  
Cross Sectional

Asthma is a chronic inflammatory airway disease, associated with systemic inflammation. Omega-3 polyunsaturated fatty acids (n-3 PUFA) have established anti-inflammatory effects, thus having potential as an adjunct therapy in asthma. This study aimed to compare erythrocyte n-3 PUFA in adults with (n = 255) and without (n = 137) asthma and determine the relationship between erythrocyte n-3 PUFA and clinical asthma outcomes. Subjects had blood collected, lung function measured and Juniper Asthma Control Questionnaire (ACQ) score calculated. Fatty acids were measured in erythrocyte membranes by gas chromatography, and the omega-3 index (O3I) was calculated (% eicosapentaenoic acid + % docosahexaenoic acid). O3I was similar in subjects with and without asthma (p = 0.089). A higher O3I was observed in subjects with controlled or partially controlled asthma (ACQ < 1.5) compared to subjects with uncontrolled asthma (ACQ ≥ 1.5) (6.0% (5.4–7.2) versus 5.6% (4.6–6.4) p = 0.033). Subjects with a high O3I (≥8%) had a lower maintenance dose of inhaled corticosteroids (ICS) compared to those with a low O3I (<8%) (1000 μg (400–1000) versus 1000 μg (500–2000) p = 0.019). This study demonstrates that a higher O3I is associated with better asthma control and with lower ICS dose, suggesting that a higher erythrocyte n-3 PUFA level may have a role in asthma management.

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