scholarly journals Proposta de Protocolo para Redução dos Riscos e Otimização da Sensibilidade nos Exames de Imagem em Pessoas com Diabetes

2021 ◽  
Vol 34 (13) ◽  
Author(s):  
Sara Donato ◽  
Helder Simões ◽  
Paulo Donato
Keyword(s):  
Chronic Disease ◽  
Lactic Acidosis ◽  
Portuguese Population ◽  
Common Chronic Disease ◽  
Iodinated Contrast

Diabetes is a very common chronic disease in the Portuguese population, with an estimated prevalence of 13.6% in the adults. Doubts often arise regarding the best preparation and the risks associated with doing imaging tests in these patients. In this article we intend to review the main precautions in imaging tests in people with diabetes and to suggest a guideline to reduce the risks and optimize the sensitivity of these tests in this population. The main topics addressed in this article are the need to suspend metformin after the administration of endovascular iodinated contrast due to the risk of lactic acidosis, the precautions in insulin-treated patients or those taking medicines with a higher risk of hypoglycemia when performing imaging tests that require fasting, and the influence of hyperglycemia and of anti-diabetic therapy on the sensitivity of PET-FDG. With this review and the presentation of a guideline, we intend to demystify and simplify the management of individuals with diabetes who are undergoing imaging tests.

scholarly journals Immunity and its role in periodontal diseases

2017 ◽  
Vol 63 (1) ◽  
pp. 24-27
Author(s):  
Irina Dumitrache ◽  
Keyword(s):  
Immune Response ◽  
Chronic Disease ◽  
Periodontal Disease ◽  
Clinical Efficacy ◽  
Periodontal Diseases ◽  
Adult Population ◽  
Host Immune Response ◽  
Immunomodulatory Therapy ◽  
Common Chronic Disease

Periodontal disease is one of the most common chronic disease, with a prevalence between 5% and 30% in adult population aged 25-75. In the pathogenesis of periodontal disease, the host immune response has a great importance and in the last years it has been underlined the role of immunomodulatory therapy in the management of periodontal disease. Septilin is a herbal immunomodulatory with clinical efficacy proven in the periodontal disease.

scholarly journals Development and evaluation of a brief self-completed family history screening tool for common chronic disease prevention in primary care

2013 ◽  
Vol 63 (611) ◽  
pp. e393-e400 ◽  
Author(s):  
Fiona M Walter ◽  
A Toby Prevost ◽  
Linda Birt ◽  
Nicola Grehan ◽  
Kathy Restarick ◽  
...  
Keyword(s):  
Primary Care ◽  
Chronic Disease ◽  
Family History ◽  
Disease Prevention ◽  
Screening Tool ◽  
Chronic Disease Prevention ◽  
Common Chronic Disease

scholarly journals Genetic diversity and disease susceptibility

1997 ◽  
Vol 352 (1357) ◽  
pp. 1045-1050 ◽  
Author(s):  
Walter F. Bodmer
Keyword(s):  
Genetic Diversity ◽  
Chronic Disease ◽  
Disease Prevention ◽  
Life Insurance ◽  
Disease Susceptibility ◽  
Genomic Analysis ◽  
Human Populations ◽  
Common Chronic Disease ◽  
Clear Cut ◽  
Targeted Approach

The range of genetic diversity within human populations is enormous. Genetic susceptibility to common chronic disease is a significant part of this genetic diversity, which also includes a variety of rare, clear–cut, inherited diseases. Modern DNA–based genomic analysis can now routinely lead to the identification of genes involved in disease susceptibility, provides the basis for genetic counselling in affected families, and can be used more widely for a genetically targeted approach to disease prevention. This naturally raises problems concerning the use of information not just in an individulal's decisions, but also for employment, and health and life insurance.

scholarly journals Continuation or termination of metformin in diabetic patients exposed to iodinated contrast medium?

2019 ◽  
Vol 8 (3) ◽  
pp. 185-189
Author(s):  
Mohamad Ali Dayani
Keyword(s):  
Renal Function ◽  
Glomerular Filtration Rate ◽  
Lactic Acidosis ◽  
Filtration Rate ◽  
Estimated Glomerular Filtration Rate ◽  
Medical Condition ◽  
Diabetic Patients ◽  
Iodinated Contrast Media ◽  
Iodinated Contrast Medium ◽  
Iodinated Contrast

Lactic acidosis (LA) secondary to metformin administration is a rare incident with a very highmortality rate (≥50%). Hypoxia has been suggested to contribute to metformin-associatedlactic acidosis (MALA) in 90% of patients developing this condition. In susceptible patientssuch as those with renal insufficiency, the level of plasma metformin is increased particularlyafter exposure to iodinated contrast media (ICM). One major concern in patients with renalinsufficiency is to adjust the metformin dose based on the renal functional capacity prior to ICMexamination. In this review, we assessed metformin tolerable threshold in diabetic patients withrenal failure. We also reviewed metformin withdrawal criteria in patients with chronic kidneydisease (CKD) exposed to intravenous ICM during angiography. Our results indicated that inpatients with insufficient renal function (i.e. 30< estimated glomerular filtration rate(eGFR) <60and 30<eGFR<45 mL/min/1.73 m2), or those with acceptable renal function (eGFR ≥60 mL/min/1.73 m2) and concomitant comorbidities, the decision to withhold or reinitiate metforminshould be based on patient’s medical condition.

scholarly journals Management of Diabetes Mellitus in Patients with Chronic Liver Diseases

2019 ◽  
Vol 2019 ◽  
pp. 1-9 ◽  
Author(s):  
Yingying Zhao ◽  
Huichun Xing ◽  
Xiaomei Wang ◽  
Weini Ou ◽  
Hong Zhao ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Diabetes Mellitus ◽  
Liver Cirrhosis ◽  
Chronic Disease ◽  
Antiviral Treatment ◽  
Close Correlation ◽  
Effective Control ◽  
Cerebral Vessel ◽  
Common Chronic Disease

Diabetes mellitus (DM) is a common chronic disease affecting humans globally. During the last few years, the incidence of diabetes has increased and has received more attention. In addition to growing DM populations, DM complications are involving injuries to more organs, such as the heart and cerebral vessel damage. DM complications can reduce quality of life and shorten life spans and eventually also impede social and economic development. Therefore, effective measures to curb the occurrence and development of diabetes assist in improving patients’ quality of life, delay the progression of DM in the population, and ease a social burden. The liver is regarded as an important link in the management and control of DM, including the alleviation of glucose metabolism and lipid metabolism and others via glucose storage and endogenous glucose generation from glycogen stored in the liver. Liver cirrhosis is a very common chronic disease, which often lowers the quality of life and decreases life expectancy. According to a growing body of research, diabetes shows a close correlation with hepatitis, liver cirrhosis, and liver cancer. Moreover, coexistence of liver complications would accelerate the deterioration of patients with diabetes. Liver cirrhosis and diabetes influence each other. Thus, in addition to pharmacological treatments and lifestyle interventions, effective control of cirrhosis might assist in a better management of diabetes. When it comes to different etiologies of liver cirrhosis, different therapeutic methods, such as antiviral treatment, may be more effective. Effective control of cirrhosis might be a strategy for better management of diabetes.

Chronic rhinosinusitis: a microbiome in dysbiosis and the search for alternative treatment options

2016 ◽  
Vol 37 (3) ◽  
pp. 149 ◽  
Author(s):  
Amanda Bordin ◽  
Hanna E Sidjabat ◽  
Kyra Cottrell ◽  
Anders Cervin
Keyword(s):  
Chronic Disease ◽  
Chronic Rhinosinusitis ◽  
Alternative Treatment ◽  
Treatment Options ◽  
Current Treatment ◽  
Multifactorial Disease ◽  
Healthy Human ◽  
Common Chronic Disease ◽  
The Future ◽  
Bacterial Microbiome

Chronic rhinosinusitis (CRS) is a common chronic disease. While CRS is a multifactorial disease, many cases involve an imbalance in the sinus bacterial microbiome. This article reviews the composition of the healthy human sinus microbiome compared to the microbiome of CRS patients. Issues with current treatment options, particularly antibiotics, are discussed. Insights into the future of CRS treatment are also explored, principally with regards to probiotics.

Outcomes Research in the Treatment of Asthma

2010 ◽  
pp. 78-99
Author(s):  
Ram C. Neupane ◽  
Jason Turner
Keyword(s):  
United States ◽  
Chronic Disease ◽  
Medical Expenditure Panel Survey ◽  
The United States ◽  
Medical Expenditure ◽  
National Inpatient Sample ◽  
Therapeutic Goals ◽  
Common Chronic Disease ◽  
The Government ◽  
The Cost

Asthma is a common chronic disease in the United States, with increasing prevalence. Many patients do not realize therapeutic goals because of poor disease management. The purpose of this study is to examine the costs of the commonly used drugs used to treat asthma. We examined the contribution of individual, government and private agencies for medication payment. We next compared the prescription cost to the cost of emergency room visits. The data are taken from the Medical Expenditure Panel Survey. SAS Enterprise Guide was used for preprocessing and data visualization. It was found that prednisone is the cheapest drug and the drug, albuterol, is the most common, even if it is more expensive. The contribution of the government is higher than the amount paid by individuals and other agencies. We examined data from the National Inpatient Sample to investigate trends in asthma as well.

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