Validation of the Skindex-29 Questionnaire: Portuguese Version (Portugal)

Introduction: There is an increasing interest regarding the impact of skin diseases on quality of life. Skindex-29 is a questionnaire developed to evaluate this impact. This study aimed to validate Skindex-29 for the Portuguese population.Material and Methods: From the 81 approached patients from two clinics, only 75 finished the study: 35 with skin disease and 40 without. A translation and back-translation were performed. Concerning accuracy and discrimination power, the scores were submitted to ROC curve analysis after being compared between both groups through Mann-Whitney test. Internal consistency was measured using Cronbach’s α coefficient. Test/retest of each scale was assessed by the intra-class correlation coefficient, and by Kappa coefficient of agreement. Convergent validity was evaluated through Spearman correlations between Skindex-29 scores and SF-12 subscales. SPSS statistics and values of p < 0.05 with 95% confidence intervals were considered statistically significant.Results: The Skindex-29 demonstrated to be an accurate instrument and statistically significant differences were found when comparing the disease and without-disease groups (p < 0.001). The reliability was high (Cronbach’s α > 0.80) for each dimension ('Symptoms', 'Emotions' and 'Functioning') and for test-retest (ICC > 0.90, K > 0.494). About convergent validity, Skindex-29 Total score and the questions about 'Symptoms' and 'Functioning' were statistically correlated with the questions regarding the physical state of the SF-12 (-0.478; -0.459; -0.405, respectively).Discussion: Results suggest that Skindex-29 can be used as an instrument to evaluate skin diseases’ effect on quality of life in Portugal, being accurate and reliable. Despite having similar general health profiles as other individuals, dermatological patients showed a lower quality of life due to their disease. Results showed that Skindex-29 was better at assessing physical components rather than mental oremotional components.Conclusion: Skindex-29 appears to have evidence of validity including accuracy and reliability to be used as an instrument to evaluate the impact of skin diseases on quality of life in Portugal.

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Validation of a scale assessing the impact of periodontal diseases on patients' quality of life in Bulgaria (pilot research)

Brazilian Dental Journal ◽

10.1590/s0103-64402012000500017 ◽

2012 ◽

Vol 23 (5) ◽

pp. 570-574 ◽

Cited By ~ 2

Author(s):

Nina Musurlieva ◽

Maria Stoykova ◽

Doychin Boyadjiev

Keyword(s):

Quality Of Life ◽

Sample Size ◽

Periodontal Diseases ◽

Sample Size Calculation ◽

Discrimination Power ◽

Related Quality ◽

Health Related ◽

Initial Interviews ◽

The Impact

The aim of the paper is to present the validation of a scale for assessing the impact of periodontal diseases on individuals' quality of life in Bulgaria. A pilot research was made among 30 diagnosed patients with periodontitis visiting the Department of Periodontology, Faculty of Dental Medicine, Medical University of Plovdiv, Bulgaria. The minimum sample size of 30 people was established based on a power analysis for sample size calculation. The mean age of participants was 48.95 ± 11.85 years, being 56.67 ± 9.05 years for males and 43.33 ± 9.05 years for females. Standard interviews were conducted using a specific instrument: self-designed questionnaire and a 5-degree ranked scale, containing initially 11 questions. The interviews were repeated after 3 months with the same patients for retest analysis. The data was statistically processed using SPSS v.13 software. Results received after the initial interviews: Cronbach's coefficient (α=0.882), Spearman-Brown coefficient (r sb=0.998), average inter-item correlation coefficient (R=0.426), difficulty of the questions from 0.173 to 0.757 and discrimination power from 0.405 to 0.809. Results after the second interviews: α=0.883, r sb=0.998, R=0.507, difficulty from 0.287 to 0.757 and discrimination power from 0.524 to 0.809. In two of the questions, a low level of inter-item correlation with the rest of the items was found and they were excluded. The final version of the questionnaire contained 9 questions. The validation proved that the developed scale is sufficiently reliable and will be used in the final research, the first one to use such an instrument for measuring oral health-related quality of life in Bulgaria.

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Dermatology quality of life scales -a measure of the impact of skin diseases

British Journal of Dermatology ◽

10.1046/j.1365-2133.1997.d01-1169.x ◽

1997 ◽

Vol 136 (2) ◽

pp. 202-206 ◽

Cited By ~ 28

Author(s):

M. MORGAN ◽

R. McCREEDY ◽

J. SIMPSON ◽

R.J. HAY

Keyword(s):

Quality Of Life ◽

Skin Diseases ◽

The Impact

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Evaluation of life quality in children with dermatological diseases (literature review)

Modern pediatrics. Ukraine ◽

10.15574/sp.2021.115.61 ◽

2021 ◽

pp. 61-68

Author(s):

O.M. Mochulska ◽

Keyword(s):

Quality Of Life ◽

Skin Diseases ◽

Life Quality ◽

Clinical Problem ◽

Healthy Person ◽

Point Of View ◽

Disease Assessment ◽

Dermatological Diseases ◽

The Impact

Skin diseases have become one of the most relevant problem due to their global prevalence and intensive growth nowadays. Significantly increased the interest in studying of the life quality of patients with acute and chronic dermatological diseases. The life quality of the patient is the most objective characteristic of the impact of the disease on the patient's condition and various areas of his activity. Emotional or social disorders caused by the disease often do not allow the patient to feel full and healthy person even if clinical recovery. The peculiarities of patients' perception of somatic disease significantly affect both on its course and on the effectiveness of therapeutic measures. Skin diseases form an aspect of life quality that can be dangerous for the prognosis. Dermatological diseases can lead to significant limitations in the physical, emotional and social aspects of patients' lives and can interfere with success in learning and at work, as well as in personal life. In dermatology to assess the quality of life of patients are used: general medical scales, special dermatological scales, dermatological scales for certain nosologies. Purpose — to analyze literary datas on the research methods of life quality in children with dermatological diseases. Conclusions. Determining and evaluating indicators of life quality in patients is a valuable and reliable indicator of the general condition, that allows to monitor the effectiveness of treatment depending on the patient's condition and creates an objective picture of the disease. Assessment of quality of life in patients with dermatological diseases makes it possible to understand the essence of the clinical problem, to determine the most rational method of treatment, as well as to assess its expected results by parameters that are at the intersection between the scientific approach and the patient's point of view. No conflict of interest was declared by the author. Key words: assessment of life quality, dermatological diseases, children.

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Responsiveness and Convergent Validity of QLU-C10D and EQ-5D-3L in Assessing Short-Term Quality of Life Following Esophagectomy

10.21203/rs.3.rs-164925/v1 ◽

2021 ◽

Author(s):

Norma B. Bulamu ◽

Ravi Vissapragada ◽

Gang Chen ◽

Julie Ratcliffe ◽

Louise A. Mudge ◽

...

Keyword(s):

Quality Of Life ◽

Convergent Validity ◽

Controlled Trial ◽

Short Term ◽

Role Function ◽

Emotional Function ◽

Ceiling Effects ◽

The Impact ◽

Utility Scores

Abstract Aim: This study assessed the responsiveness and convergent validity of two preference-based measures; the newly developed cancer-specific EORTC Quality of Life Utility Measure-Core 10 dimensions (QLU-C10D) relative to the generic three-level version of the EuroQol 5 dimensions (EQ-5D-3L) in evaluating short-term quality-of-life outcomes/utilities after esophagectomy.Methods: Participants were enrolled in a multicentre 2×2 factorial randomised controlled trial to determine the impact of preoperative and postoperative immunonutrition versus standard nutrition in patients with esophageal cancer. Quality-of-life was assessed seven days before and 42 days after esophagectomy. Standardized Response Mean and Effect Size were calculated to assess responsiveness. Ceiling effects for each dimension were calculated as the proportion of the best level responses for that dimension. Convergent validity was assessed using Spearman’s correlation and the level of agreement was explored using Bland–Altman plots. Regression analysis was performed to identify which demographic and clinical factors influenced quality of life. Results: Respondents were 164, predominantly male (81%) with mean age of 63 years. Quality-of-life significantly reduced on both measures with large effect sizes (>80), and greater mean difference on QLU-C10D. Ceiling effects were observed with social activities (86%), mobility (67%), anxiety (55%) and pain (19%) dimensions on EQ-5D-3L. For QLU-C10D ceiling effects were observed with emotional function (53%), physical function (16%), nausea (35%), sleep (31%), bowel problems (21%) and pain (20%). A strong correlation (r=0.71) was observed between EQ-5D-3L anxiety and QLU-C10D emotional function dimensions. Good agreement (3.7% observations outside the limits of agreement) was observed between the utility scores. Blood loss and blood transfusion predicted EQ-5D-3L utility while smoking and tumour length >3cm were predictive of QLU-C10D utility. Changes in QLQ-C30 dimensions of emotional function, role function and pain were predictive of changes in EQ-5D-3L utility while changes in physical, social and role function as well as all the symptom scales were predictive of change in QLU-C10D utility. Conclusion: Although there is strong agreement between utility scores, QLU-C10D was more sensitive to short-term utility changes following esophagectomy. Cognisant of requirements by policy makers to apply generic utility measures in cost effectiveness studies, disease-specific measures should be used alongside the generic measures. Trial registrationThe trial was registered with the Australian New Zealand Clinical Trial Registry (ACTRN12611000178943) on the 15th February 2011.

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Responsiveness and convergent validity of QLU-C10D and EQ-5D-3L in assessing short-term quality of life following esophagectomy

Health and Quality of Life Outcomes ◽

10.1186/s12955-021-01867-w ◽

2021 ◽

Vol 19 (1) ◽

Author(s):

Norma B. Bulamu ◽

Ravi Vissapragada ◽

Gang Chen ◽

Julie Ratcliffe ◽

Louise A. Mudge ◽

...

Keyword(s):

Quality Of Life ◽

Convergent Validity ◽

Controlled Trial ◽

Short Term ◽

Clinical Trial Registry ◽

Emotional Function ◽

Ceiling Effects ◽

Randomised Controlled ◽

The Impact

Abstract Aim This study assessed the responsiveness and convergent validity of two preference-based measures; the newly developed cancer-specific EORTC Quality of Life Utility Measure-Core 10 dimensions (QLU-C10D) relative to the generic three-level version of the EuroQol 5 dimensions (EQ-5D-3L) in evaluating short-term health related quality of life (HRQoL) outcomes after esophagectomy. Methods Participants were enrolled in a multicentre randomised controlled trial to determine the impact of preoperative and postoperative immunonutrition versus standard nutrition in patients with esophageal cancer. HRQoL was assessed seven days before and 42 days after esophagectomy. Standardized Response Mean and Effect Size were calculated to assess responsiveness. Ceiling effects for each dimension were calculated as the proportion of the best level responses for that dimension at follow-up/post-operatively. Convergent validity was assessed using Spearman’s correlation and the level of agreement was explored using Bland–Altman plots. Results Data from 164 respondents (mean age: 63 years, 81% male) were analysed. HRQoL significantly reduced on both measures with large effect sizes (> 0.80), and a greater mean difference (0.29 compared to 0.16) on QLU-C10D. Both measures had ceiling effects (> 15%) on all dimensions at baseline. Following esophagectomy, ceiling effects were observed with self-care (86%), mobility (67%), anxiety/depression (55%) and pain/discomfort (19%) dimensions on EQ-5D-3L. For QLU-C10D ceiling effects were observed with emotional function (53%), physical function (16%), nausea (35%), sleep (31%), bowel problems (21%) and pain (20%). A strong correlation (r = 0.71) was observed between EQ-5D-3L anxiety and QLU-C10D emotional function dimensions. Good agreement (3.7% observations outside the limits of agreement) was observed between the utility scores. Conclusion The QLU-C10D is comparable to the more widely applied generic EQ-5D-3L, however, QLU-C10D was more sensitive to short-term utility changes following esophagectomy. Cognisant of requirements by policy makers to apply generic utility measures in cost effectiveness studies, the disease-specific QLU-C10D should be used alongside the generic measures like EQ-5D-3L. Trial registration: The trial was registered with the Australian New Zealand Clinical Trial Registry (ACTRN12611000178943) on the 15th of February 2011.

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Development and Validation of Nasal Polyposis Quality of Life Questionnaire (NPQ)

10.21203/rs.3.rs-89698/v1 ◽

2020 ◽

Author(s):

Ilaria Baiardini ◽

Giovanni Paoletti ◽

Alessia Mariani ◽

Luca Malvezzi ◽

Francesca Pirola ◽

...

Keyword(s):

Quality Of Life ◽

Convergent Validity ◽

Nasal Polyposis ◽

Minimal Important Difference ◽

Dimensional Structure ◽

Life Questionnaire ◽

Quality Of Life Questionnaire ◽

Development And Validation ◽

The Impact

Abstract BACKGROUND: To date, no disease-specific tool is available to assess the impact of Chronic Rhinosinusitis with Nasal Polyps (CRSwNP) on Health Related Quality of Life (HRQoL). Therefore, the purpose of this study was to develop and validate a questionnaire specifically designed to this aim: the Nasal Polyposis Quality of Life questionnaire –NPQ.METHODS: According to the current guidelines, the development and validation of the NPQ occurred in two separate steps involving different groups of patients.RESULTS: In the development process of NPQ an initial list of items of 40 items was given to 60 patients with CRSwNP; the 27 most significant items were selected and converted into questions. The validation procedure involved 107 patients (mean age 52.9±12.4). NPQ revealed a five-dimensional structure and high levels of internal consistency (Cronbach's alpha 0.95). Convergent validity (Spearman’ coefficient r=0.75; p< 0.01), discriminant validity (sensitivity to VAS score), reliability in a sample of patients with a stable health status (Interclass Coefficient 0.882) were satisfactory. Responsiveness to clinical changes was accomplished. The minimal important difference was 7. CONCLUSIONS: NPQ is the first questionnaire for the assessment of HRQoL in CRSwNP. Our results provide that the new tool is valid, reliable, and sensitive to individual changes.

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Brazilian version of the Overall Assessment of the Speaker's Experience of Stuttering - Adults protocol (OASES-A)

Jornal da Sociedade Brasileira de Fonoaudiologia ◽

10.1590/s2179-64912012000200010 ◽

2012 ◽

Vol 24 (2) ◽

pp. 145-151 ◽

Cited By ~ 10

Author(s):

Eliane Lopes Bragatto ◽

Ellen Osborn ◽

J. Scott Yaruss ◽

Robert Quesal ◽

Ana Maria Schiefer ◽

...

Keyword(s):

Quality Of Life ◽

Treatment Options ◽

Brazilian Portuguese ◽

Emotional States ◽

Self Assessment ◽

Brazilian Version ◽

Assessment And Treatment ◽

Back Translation ◽

The Impact

PURPOSE: To verify the applicability of the protocol Overall Assessment of the Speaker's Experience of Stuttering - Adults (OASES-A), translated into Brazilian Portuguese, in a sample of adults who stutter. METHODS: The Brazilian Portuguese version of the OASES-A protocol was individually applied to 18 people who stutter. The classification of stuttering severity was based on the Stuttering Severity Instrument for Children and Adults (SSI-3) protocol. Translation and back-translation processes were carried out by specialists, considering semantic, conceptual, cultural, and idiomatic equivalences. RESULTS: There was no correlation between the severity degrees of stuttering assessed by the SSI-3 protocol and the self-assessment performed using the OASES-A. Subjects reported impairments in perceived fluency; speech ability; level of knowledge about stuttering and treatment options; use of confrontational techniques; quality of life. They also mentioned having difficulty coping with emotional states such as anxiety and embarrassment, and with communication in daily situations. CONCLUSION: The OASES-A protocol is useful in the assessment and treatment of stutterers, as it provides specialized speech-language pathologists with sutterers' self-perception regarding their communication difficulties and the impact of stuttering on their quality of life.

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The Evolution of Quality of Life Assessment and Use in Dermatology

Dermatology ◽

10.1159/000496923 ◽

2019 ◽

Vol 235 (3) ◽

pp. 167-174 ◽

Cited By ~ 13

Author(s):

Pavel V. Chernyshov

Keyword(s):

Quality Of Life ◽

Skin Diseases ◽

Life Quality ◽

Life Assessment ◽

Core Outcome Sets ◽

The Moment ◽

Development And Validation ◽

The Impact ◽

Selection Of

The creation of the Dermatology Life Quality Index (DLQI) questionnaire facilitated many studies on the impact of skin diseases on patients’ quality of life (QoL). Many national and international guidelines recommend QoL assessment in dermatology, and some of them contain detailed recommendations on treatment goals and changes of treatment approaches based on DLQI score banding and minimal clinically important difference. The methodology of QoL in strument development and validation is constantly becoming more rigorous. Initiatives on selection of core outcome sets for skin diseases are focused on clinical trials but may also be beneficial for clinicians. There are various benefits of using QoL information in clinical practice, but experience of this is very limited at the moment. QoL assessment in dermatology is a rapidly developing field with a gradual shift from theory to practice.

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Quality of Life in POP: Validity, Reliability and Responsiveness of the Prolapse Quality of Life Questionnaire (P-QoL) in Spanish Women

International Journal of Environmental Research and Public Health ◽

10.3390/ijerph17051690 ◽

2020 ◽

Vol 17 (5) ◽

pp. 1690 ◽

Cited By ~ 1

Author(s):

Beatriz Sánchez-Sánchez ◽

Maria José Yuste-Sánchez ◽

Beatriz Arranz-Martín ◽

Beatriz Navarro-Brazález ◽

Helena Romay-Barrero ◽

...

Keyword(s):

Quality Of Life ◽

Pelvic Floor ◽

Convergent Validity ◽

Discriminant Validity ◽

Short Form ◽

Life Questionnaire ◽

Quality Of Life Questionnaire ◽

Spanish Women ◽

The Impact

The Prolapse Quality of Life Questionnaire (P-QoL) is a specific questionnaire created to assess the impact of pelvic organ prolapse on women’s quality of life. The aim of the present study was to cross-culturally adapt and assess the psychometric properties of the P-QoL for Spanish women. The cross-cultural adaptation was conducted by a standardized translation/back-translation method. Psychometric analysis was performed by assessing the validity, reliability, responsiveness and feasibility. A total of 200 Spanish women were recruited and assigned to symptomatic and asymptomatic groups. The Spanish P-QoL version demonstrated good content validity. Convergent validity showed high intercorrelations with the Pelvic Floor Distress Inventory short form and the Pelvic Floor Impact Questionnaire short form. The discriminant validity showed statistically significant differences between the symptomatic and the asymptomatic groups. The internal consistency was high and of acceptable values. The test-retest reliability was shown to be high in all the cases. Regarding responsiveness, the effect size and standardized response mean demonstrated moderate values. The average time for administration was 10 (3) min. The Spanish P-QoL showed considerable support for the appropriate metric properties of validity, reliability, responsiveness and feasibility to evaluate the symptom severity and its impact on the quality of life in Spanish women with urogenital prolapse.

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