Rare radiological feature: lung cavitation due to coronavirus disease 2019 pneumonia

A 25-year-old man, who was taking treatment for his poorly controlled asthma, presented with symptoms of cough with expectoration, gradually progressive shortness of breath, fever on and off and diffuse wheeze for 2 years. Chest X-ray revealed hyperinflation of lung field with dense opacification at right upper lobe. High-resolution CT chest showed bilateral patchy consolidation, central bronchiectasis and high-attenuation mucus (HAM) impaction. His blood absolute eosinophil count, total serum IgE level, Aspergillus fumigatus specific IgE and IgG level were 1910, 16760 kU/L, 59.8 kU/L and 147.41 kU/L, respectively. Diagnosis of allergic broncho pulmonary aspergillosis (ABPA) was established according to International Society for Human and Animal Mycology society guidelines. He was started on systemic steroids and doing well after 6 months of follow-up. Our case illustrates HAM, which is a rare but typical radiological feature of ABPA.

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High prevalence of variants in skeletal dysplasia associated genes in individuals with short stature and minor skeletal anomalies

Acta Endocrinologica ◽

10.1530/eje-21-0557 ◽

2021 ◽

Author(s):

Lucia Sentchordi-Montané ◽

Sara Benito-Sanz ◽

Miriam Aza-Carmona ◽

Francisca Díaz-González ◽

Silvia Modamio-Høybjør ◽

...

Keyword(s):

Short Stature ◽

Skeletal Dysplasia ◽

Genetic Defect ◽

Radiological Feature ◽

Molecular Defect ◽

Skeletal Dysplasias ◽

Skeletal Anomalies ◽

Radiological Data ◽

High Prevalence ◽

Next Generation Sequencing Ngs

Objective: Next generation sequencing (NGS) has expanded the diagnostic paradigm turning the focus to the growth plate. The aim of the study was to determine the prevalence of variants in genes implicated in skeletal dysplasias in probands with short stature and mild skeletal anomalies. Design: Clinical and radiological data were collected from 108 probands with short stature and mild skeletal anomalies. Methods: A customized skeletal dysplasia NGS panel was performed. Variants were classified using ACMG recommendations and Sherloc. Anthropometric measurements and skeletal anomalies were subsequently compared in those with or without an identified genetic defect. Results: Heterozygous variants were identified in 21/108 probands (19.4%). Variants were most frequently identified in ACAN (n=10) and IHH (n=7) whilst one variant was detected in COL2A1, CREBBP, EXT1 and PTPN11. Statistically significant differences (p<0.05) were observed for sitting height/height (SH/H) ratio, SH/H ratio SDS and the SH/H ratio SDS >1 in those with an identified variant compared to those without. Conclusions: A molecular defect was elucidated in a fifth of patients. Thus, the prevalence of mild forms of skeletal dysplasias is relatively high in individuals with short stature and mild skeletal anomalies, with variants in ACAN and IHH accounting for 81% of the cases. An elevated SH/H ratio appears to be associated with a greater probability in detecting a variant, but no other clinical or radiological feature has been found determinant to finding a genetic cause. Currently, we cannot perform extensive molecular studies in all short stature individuals so detailed clinical and radiological phenotyping may orientate which are the candidate patients to obtain worthwhile results. In addition, detailed phenotyping of probands and family members will often aid variant classification.

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Spiking of the tibial tubercles--a radiological feature of osteoarthritis?

Annals of the Rheumatic Diseases ◽

10.1136/ard.55.2.105 ◽

1996 ◽

Vol 55 (2) ◽

pp. 105-108 ◽

Cited By ~ 8

Author(s):

S Donnelly ◽

D J Hart ◽

D V Doyle ◽

T D Spector

Keyword(s):

Radiological Feature

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Osteosarcoma arising in a case of osteofibrous dysplasia of tibia with classic adamantinoma: A case report and literature review

Journal of Orthopaedics Trauma and Rehabilitation ◽

10.1177/22104917211025808 ◽

2021 ◽

Vol 28 ◽

pp. 221049172110258

Author(s):

Weiguo Li ◽

Ka-Lok Mak ◽

Tsz W Yau ◽

Tit L Lam ◽

Chak L Chan ◽

...

Keyword(s):

Case Report ◽

Literature Review ◽

Distal Part ◽

Neoplastic Transformation ◽

Radiological Feature ◽

Small Lesion ◽

Osteofibrous Dysplasia ◽

Radiological Features ◽

Chondroblastic Osteosarcoma

A five-year-old boy presented with left tibial swelling; there was a typical radiological feature of osteofibrous dysplasia. He was observed until the age of 14 years; there was development of aggressive radiological features. Biopsy revealed chondroblastic osteosarcoma. It was excised and the histology revealed chondroblastic osteosarcoma. A small lesion distal to the main tumour revealed adamantinoma within a background of feature of osteofibrous dysplasia. Proximally, feature of osteofibrous dysplasia was identified focally. The finding of adamantinoma over the distal part of the lesion supports that feature of osteofibrous dysplasia may be a precursor of adamantinoma. They may be a spectrum of diseases with multistep neoplastic transformation. The osteosarcoma may be a result of de-differentiation from adamantinoma. This case is remarkable as the patient was only 14 years old and the tumour showed typical features of osteosarcoma, with feature of osteofibrous dysplasia and adamantinoma found in the same specimen. Feature of osteofibrous dysplasia may be a precursor of adamantinoma, and adamantinoma may dedifferentiate into osteosarcoma.

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Radiological feature of colonic atresia

Archives of Disease in Childhood - Fetal and Neonatal Edition ◽

10.1136/archdischild-2017-314482 ◽

2018 ◽

Vol 103 (3) ◽

pp. F263-F263 ◽

Cited By ~ 1

Author(s):

Jia-liang Zhou ◽

Yuan-long Fang ◽

Song Tian ◽

Xiao-chun Zhu ◽

Wu-ping Ge

Keyword(s):

Radiological Feature ◽

Colonic Atresia

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Radiological Images in the Construction of Hybrid Intelligent System

10.37690/1811-0193-2020-4-43-50 ◽

2020 ◽

pp. 43-50

Author(s):

B. A. Kobrinskii ◽

◽

D. D. Dolotova ◽

V. V. Donitova ◽

A. V. Gavrilov ◽

...

Keyword(s):

Computed Tomography ◽

Cerebral Ischemia ◽

Computed Tomography Angiography ◽

Intelligent Systems ◽

Intelligent System ◽

Radiological Feature ◽

Chronic Cerebral Ischemia ◽

Computed Tomography Images ◽

Linguistic Rules ◽

Hybrid Intelligent System

So far, the concept of image row or tuples in the development of intelligent systems has been discussed in relation to the role of phenotypic (external) manifestations of diseases in diagnostics. This study introduces the idea of neuroimaging tuples as a tool to make a prognosis of the course of chronic cerebral ischemia. The phenomenon of leukoaraiosis is analyzed as a radiological feature of chronic brain ischemia and a predictor of stroke. Image tuples are formed from the results of computed tomography, computed tomography angiography, magnetic resonance imaging, of 85 patients with chronic cerebral ischemia. Native computed tomography images were processed with adaptive filtering methods. Computed tomography angiography results were processed through a vesselness filter that allows development of 3D reconstructions of vasculature in leukoaraiosis areas. The problem of fuzzy images, the principles of comparative analysis of images and the possibility of using confidence factors in the image tuples are discussed in the article. A scheme of a hybrid intelligent system that combines traditional logic-linguistic rules and images based on primary information and reconstruction of the original DICOM images in the knowledge base was developed. The sphere of the application is stroke risk prediction using an intelligent system.

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Diffuse Parenchymal Neurocysticercosis: A Case Report and Review of Literature

Indian Journal of Neurotrauma ◽

10.1055/s-0040-1713575 ◽

2020 ◽

Vol 17 (02) ◽

pp. 149-152

Author(s):

Hanuman Prasad Prajapati

Keyword(s):

Skeletal Muscles ◽

Taenia Solium ◽

Radiological Feature ◽

Management Plan ◽

The Body ◽

Review Of Literature ◽

Subcutaneous Tissues ◽

The Central Nervous System ◽

Tomography Scan ◽

Widespread Dissemination

AbstractNeurocysticercosis is the commonest parasitic disease of the central nervous system and the leading cause of seizure in the developing world. Human cysticercosis is caused by the dissemination of the embryo of Taenia solium in the intestine via the hepatoportal system to the tissues and organs of the body. The organs most commonly affected are the subcutaneous tissues, skeletal muscles, lung, brain, eye, liver, and occasionally the heart, thyroid, and pancreas. Widespread dissemination of the cysticerci can result in the involvement of almost any organ in the body. We report a case of 60 years old male presented with head injury due to fall, which was diagnosed as diffuse parenchymal neurocysticercosis on computed tomography scan of brain. We discuss the radiological feature, diagnostic criteria, management plan, and literature review of such reported cases.

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Anterior-to-Posterior Migration of a Lumbar Disc Sequestration: Surgical Remarks and Technical Notes about a Tailored Microsurgical Discectomy

Case Reports in Surgery ◽

10.1155/2017/1762047 ◽

2017 ◽

Vol 2017 ◽

pp. 1-4 ◽

Cited By ~ 1

Author(s):

Alessandro Frati ◽

Alessandro Pesce ◽

Mauro Palmieri ◽

Tommaso Vangelista ◽

Riccardo Caruso ◽

...

Keyword(s):

Lumbar Disc ◽

Cauda Equina ◽

Rare Condition ◽

Radiological Feature ◽

Surgical Trauma ◽

Nerve Roots ◽

Surgical Decision ◽

Clinical Onset ◽

Disc Herniations ◽

Posterior Migration

Extrusion of disc material within the spinal canal complicates up to 28.6% of lumbar disc herniations. Due to the anatomical “corridors” created by the anterior midline septum and lateral membranes, relocation occurs with an anterior and anterolateral axial topography. Posterior migration is an extremely rare condition and anterior-to-posterior circumferential migration is an even rarer condition. Its radiological feature can be enigmatic and since, in more than 50% of cases, clinical onset is a hyperacute cauda equina syndrome, it may imply a difficult surgical decision in emergency settings. Surgery is the gold standard but when dealing with such huge sequestrations, standard microdiscectomy must be properly modified in order to minimize the risk of surgical trauma or traction on the nerve roots.

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