scholarly journals The Profile of Bacterial Vaginosis in Academic Hospital Surabaya: A Retrospective Study

2020 ◽  
Vol 32 (2) ◽  
pp. 141
Author(s):  
Amanda Gracia Manuputty ◽  
Sunarko Matodiharjo

Background: Bacterial vaginosis (BV) is a lower genital tract infection, which occur as a result of vaginal microbiome dysbiosis. This vaginal infection can lead to symptoms such as vaginal discharge, malodor and irritation. It is the most common condition occurred in reproductive age but may give 50–75% of asymptomatic signs. Purpose: To overview new BV patients at the Sexually Transmitted Infection Division of Dermatology and Venereology Outpatient Clinic Dr. Soetomo General Hospital Surabaya in 2015–2017. Methods: A retrospective study was performed by evaluating medical records of new BV patients, including identity, history taking, examination, diagnosis, treatment, follow up and counselling. Result: The number of new BV cases was 35 (1,38%). The most infected age group was 25–44 years old (51%), and 65.7% of them were married. The most common chief complaint was vaginal discharge without subjective complaints (74.3%), the most common type of complaint was recurrence (48.6%), the most partner roles which affected by BV patients were husbands (51.4%), history of vaginal douching (34.2%), and the most vaginal discharges were severe (75.8%). The whiff test showed positive results and pH > 4.5 in 48.6% of patients. All microscopical preparations showed clue cells. The most prescribed drug was metronidazole. Conclusion: The overview new BV cases showed a small incidence with commonly occurred among women in childbearing age and were asymptomatic. A routine high vaginal swab helps the proper diagnosis and management to prevent the recurrence and complication of BV.

2019 ◽  
Vol 11 (2) ◽  
pp. 53-59
Author(s):  
Pati Aji Achdiat ◽  
Rasmia Rowawi ◽  
Irma Fakhrosa ◽  
Hendra Gunawan ◽  
Reti Hindritiani ◽  
...  

Abstract Bacterial vaginosis (BV) is a lower genital tract infection of reproductive women which can occur in pregnant and non-pregnant women. BV in pregnant women can increase the risk of complications, including increased incidence of abortion, premature rupture of membranes, preterm birth, and babies with low birth weight. BV can also increase the risk of acquired sexually transmitted infection (STI) and their further transmission, including human immuno-deficiency virus (HIV). Each country has a different prevalence of BV. The previous report of BV prevalence in pregnant women was submitted in Jakarta, Indonesia in 1990. Until now, there is no update data of BV in pregnant women, especially in West Java, Indonesia. Thus, we conducted a descriptive observational study using a cross-sectional design and a consecutive sampling method in June 2018. This study included 60 pregnant women in the Maternal and Child Hospital, Bandung, Indonesia. Out of 60 participants, seven (11.67%) participants had BV according to Amsel criteria. Asymptomatic BV was diagnosed in all participants. This study shows the prevalence of BV in pregnant women in the Maternal and Child Hospital in Bandung during June 2018. The assessment of screening BV should be recommended as a routine workup. To avoid complications in pregnant women and infants it should not be waited for the symptoms to reveal.


Author(s):  
Lenny Irmawaty Sirait

Sexually Transmitted Infections (STIs) are various infections that can be transmitted from one person to another through sexual contact. The spread of STIs to women and men (90%) occurs through sexual intercourse, both vaginal, anal and oral, the rest through blood products or tissue transfer that has been exposed to pathogens or can be transmitted through medical devices, as well as from mother to fetus in the womb or while birth process. This study aims to determine the relationship between sexual intercourse patterns and the incidence of sexually transmitted infections in women of reproductive age at the Makassar District Health Center, East Jakarta 2019. This research method is a type of quantitative research with a cross-sectional research design, using the inclusion and exclusion criteria for a sample of 55 people, the type of data. primer, measuring instrument questionnaire and laboratory results, analysis of chi square test data. The results showed that out of 46 women of childbearing age who had a poor pattern of sexual relations and sexually transmitted infections were 41 people (89.1%) and 5 people (10.9%) had sexually transmitted infections while 9 people had a pattern of sexual intercourse. well and sexually transmitted infections were 1 person (11.1) and sexually transmitted infections were 8 people (89.9%) pvalue = 0.01 (p <0.05). Conclusion The Relationship between Sexual Relationship Patterns and the Incidence of Sexually Transmitted Infection in Women of Fertile Age at the Makassar District Health Center 2019 (p value = 0.01)


1970 ◽  
Vol 4 (1) ◽  
pp. 24-27
Author(s):  
Shameem Akhter ◽  
Humayun Satter ◽  
Shirin Tarafder ◽  
Ruhul Amin Miah ◽  
Sohely Sharmin ◽  
...  

Bacterial vaginosis is the commonest cause of abnormal vaginal discharge in women of reproductive age and require laboratory test for diagnosis . A total 200 women aged 15-45 years with history of abnormal vaginal discharge were included as study population. Fifty women without such history of discharge were taken as healthy control. Three vaginal swab samples were taken from each case and control. These swab samples were subjected to test by conventional methods such as Amsel clinical criteria, Gram stain Nugent method, culture and by newly developed BV Blue test. The results of the BVBlue test were compared with these methods to find out the efficacy of BVBlue test. Rate of detection of bacterial vaginosis (BV) cases was 21.5% by Amsel clinical criteria, 21.0% by Gram stain Nugent method, 21.0% by culture and 22% by BVBlue test among the study population. When comparing with the conventional test and culture, BVBlue test was 100% sensitive and 98% specific. It is rapid, technically simple and is suitable for screening large number of patient in short time where laboratory facilities are not developed. Key words: Bacterial Vaginosis, BVBlue test, Nugent method, Abnormal vaginal discharge. DOI: http://dx.doi.org/10.3329/bjmm.v4i1.8465 BJMM 2011; 4(1): 24-27


2013 ◽  
Vol 5 (1) ◽  
pp. 8-11 ◽  
Author(s):  
Shameem Akhter ◽  
Humayun Sattar ◽  
Ruhul Amin Miah ◽  
Ahmed Abu Saleh ◽  
Sharmeen Ahmed ◽  
...  

Bacterial vaginosis is the commonest cause of abnormal vaginal discharge in women of reproductive age. A total 200 women aged 15- 45 years with history of abnormal vaginal discharge were included as study population. Fifty women without such history of discharge were taken as healthy control. Two vaginal swab samples were taken from each case and control. These swab samples were subjected to test by Gram stain (Nugent method) and culture. 21.5 % of the cases were diagnosed as bacterial vaginosis by Gram stain (Nugent method) and 21 % by culture. Clindamycin was susceptible to G. vaginalis in (90.5%) followed by metronidazol (76.1 %), chloramphenicol (71.4 %) and erythromycin (66.7 %). Out of 50 cases of recurrent bacterial vaginosis, G. vaginalis was isolated from 15 (30 %) cases, of which 5 (33.3 %) were sensitive and 10 (66.7 %) were resistant to metronidazol, while all 15 cases were sensitive to clindamycin.DOI: http://dx.doi.org/10.3329/bjmm.v5i1.15814 Bangladesh J Med Microbiol 2011; 05 (01): 8-11


F1000Research ◽  
2017 ◽  
Vol 6 ◽  
pp. 1761 ◽  
Author(s):  
Phillip Hay

Bacterial vaginosis is the most prevalent cause of abnormal vaginal discharge in women of childbearing age. It can have a major impact on quality of life and psychological wellbeing if frequently recurrent and strongly symptomatic. The use of molecular techniques to study the vaginal microbiome is increasing our understanding of the dynamic changes in flora that occur in health and disease. It might soon be possible to separate Gardnerella into different pathogenic and non-pathogenic species. Many groups are studying compounds that can disrupt the biofilm which is dominated by Gardnerella and Atopobium vaginae. Several studies in the last decade support the concept of bacterial vaginosis as a sexually transmitted infection.


2015 ◽  
Vol 59 (5) ◽  
pp. 2825-2834 ◽  
Author(s):  
Federica Cruciani ◽  
Elena Biagi ◽  
Marco Severgnini ◽  
Clarissa Consolandi ◽  
Fiorella Calanni ◽  
...  

ABSTRACTThe healthy vaginal microbiota is generally dominated by lactobacilli that confer antimicrobial protection and play a crucial role in health. Bacterial vaginosis (BV) is the most prevalent lower genital tract infection in women in reproductive age and is characterized by a shift in the relative abundances ofLactobacillusspp. to a greater abundance of strictly anaerobic bacteria. In this study, we designed a new phylogenetic microarray-based tool (VaginArray) that includes 17 probe sets specific for the most representative bacterial groups of the human vaginal ecosystem. This tool was implemented using the ligase detection reaction-universal array (LDR-UA) approach. The entire probe set properly recognized the specific targets and showed an overall sensitivity of 6 to 12 ng per probe. The VaginArray was applied to assess the efficacy of rifaximin vaginal tablets for the treatment of BV, analyzing the vaginal bacterial communities of 22 BV-affected women treated with rifaximin vaginal tablets at a dosage of 25 mg/day for 5 days. Our results showed the ability of rifaximin to reduce the growth of various BV-related bacteria (Atopobium vaginae,Prevotella,Megasphaera,Mobiluncus, andSneathiaspp.), with the highest antibiotic susceptibility forA. vaginaeandSneathiaspp. Moreover, we observed an increase ofLactobacillus crispatuslevels in the subset of women who maintained remission after 1 month of therapy, opening new perspectives for the treatment of BV.


Diagnostics ◽  
2021 ◽  
Vol 11 (2) ◽  
pp. 191
Author(s):  
Giuseppina Campisciano ◽  
Nunzia Zanotta ◽  
Vincenzo Petix ◽  
Manuela Giangreco ◽  
Giuseppe Ricci ◽  
...  

Bacterial vaginosis (BV) affects one-third of reproductive age women, increasing the risk of acquiring sexually transmitted infections (STIs) and posing a risk for reproductive health. The current diagnosis with Gram stain (Nugent Score) identifies a transitional stage named partial BV or intermediate microbiota, raising the problem of how to clinically handle it. We retrospectively analyzed cervicovaginal swabs from 985 immunocompetent non-pregnant symptomaticspp. women (vaginal discharge, burning, itching) by Nugent score and qPCR for BV, aerobic or fungal vaginitis, and STIs (Mycoplasmas spp., Chlamydia t., Trichomonas v., and Neisseria g.). Nugent scores 0–3 and 7–10 were confirmed in 99.3% and 89.7% cases, respectively, by qPCR. Among Nugent scores 4–6 (partial BV), qPCR identified 46.1% of BV cases, with 37.3% of cases negative for BV, and only 16.7% of partial BV. Gram staining and qPCR were discordant (p value = 0.0001) mainly in the partial BV. Among the qPCR BV cases, the presence of aerobic vaginitis and STIs was identified, with a significant association (p < 0.0001) between the STIs and partial BV/overt BV. qPCR is more informative and accurate, and its use as an alternative or in combination with Gram staining could help clinicians in having an overview of the complex vaginal microbiota and in the interpretation of partial BV that can correspond to vaginitis and/or STIs.


2017 ◽  
Vol 5 (1) ◽  
pp. 5
Author(s):  
Kishor Bajracharya ◽  
Narinder Kaur ◽  
Sushama Suresh Pant

Abstract: Introduction: Infective vaginitis accounts for about 90% of all the cases of vaginal discharge in the women of reproductive age group. This includes triad of bacterial vaginosis, candidiasis and trichomoniasis. Method: The study was carried out in Lumbini Medical College and Teaching Hospital, Palpa, Nepal for a time period of 4 months. Total 125 high vaginal swabs from posterior fornix of vagina were collected from November 2014 to February 2015 in the department of Obstetrics and Gynecology, in the patients complaining of vaginal discharge. PH of the vaginal discharge was also determined by using litmus paper. Gram’s and Giemsa stain of vaginal swab smear were done to diagnose Bacterial vaginosis, Candidiasis and Trichomoniasis. Age, parity and pregnancy status of the patients were noted. Result: Out of 125 patient, bacterial vaginosis was found in 16% and candidiasis in 37%.Candidiasis and bacterial vaginosis were observed in child bearing sexually active women. Surprisingly bacterial vaginosis was not observed in pregnant women. Trichomoniasis infection was present in one case (0.8%) while severe invasive Candidiasis was observed in one woman. Conclusion: A definitive diagnosis can easily be made by Gram’s and Giemsa stain and microscopic examination of high vaginal swab. This may help in specific treatment and  prevent associated morbidity and  recurrence. Key words: Bacterial vaginosis, candidiasis, high vaginal swab, Gram’s stain, Giemsa stain.      


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