scholarly journals Microautologous Fat Transplantation (MAFT) sebagai Rekonstruksi Lanjutan pada Kasus Deformitas Maksilofasial Pasca Trauma

2021 ◽  
Vol 6 (2) ◽  
pp. 43
Author(s):  
Ardea Perdanakusuma ◽  
Ariani Primawati ◽  
Budiman Dr

Latar Belakang: Teknik Microautologous Fat Transplantation (MAFT) merupakan sebuah metode yang relatif baru untuk memindahkan lemak dari lokasi tubuh tertentu ke lokasi tubuh yang diinginkan dengan suatu alat khusus. Teknik transfer lemak sebenarnya sudah dilakukan sejak tahun 1893 namun terkendala dengan masih banyaknya lemak yang diresorpsi sehingga memerlukan beberapa kali tindakan ulangan. Teknik Microatutologus Fat Transplantation menggunakan MAFT Gun pertama kali dilakukan oleh Lin et al. pada tahun 2006. Teknik ini telah menunjukkan hasil yang baik dalam bidang estetik maupun rekonstruksi menggantikan teknik dermofat graft yang bersifat lebih invasive. Deformitas pada wajah akibat dari hilangnya sejumlah volume lemak dapat diatasi dengan MAFT Gun yang bersifat minimal invasif. Pada tulisan ini dilaporkan satu kasus penanganan deformitas maksilofasial pasca reposisi dan fiksasi fraktur tulang wajah dengan Microautologous Fat Transplantation sebagai salah satu modalitas. Pasien dan Metode: Jaringan lemak diambil dengan spuit 60 cc tekanan negatif kemudian dilakukan sentrifugasi dengan kecepatan 3000 rpm selama 10 menit untuk memisahkan komponen lemak dan plasma. Lapisan lemak murni selanjutnya ditransplantasikan pada area wajah menggunakan MAFT Gun di bawah mata 3.5 ml, pipi 20.5 ml, dagu 3 ml, dan pelipis 1 ml. Hasil: Lama tindakan 2 jam 30 menit, prosedur anestesi sedasi sedang dan blok nervus infraorbitalis, nervus mentalis, dan nervus supraorbitalis, dan nervus supratrochealis ipsilateral. Deformitas dapat teratasi, longterm follow up 3 bulan pasca operasi tidak banyak jaringan lemak yang diresorpsi, sehingga penampilan masih baik. Kesimpulan: Teknik MAFT Gun merupakan prosedur yang efektif untuk memperbaiki kontur wajah, peremajaan wajah, memperbaiki area yang cekung, dan mengembalikan volume termasuk mengoreksi deformitas wajah akibat fraktur maksilofasial pasca reposisi fraktur maksilofasial yang kurang sempurna. Prosedur yang dilakukan relatif tidak invasif. Jaringan lemak dapat diambil dari berbagai area tubuh yang memiliki jaringan lemak berlebih. Menggunakan MAFT Gun yang telah tersertifikasi, proses transfer lemak dapat dilakukan secara akurat dan konsisten. Hasil MAFT cukup memuaskan bagi pasien, sehingga memungkinkan prosedur MAFT menjadi alternatif solusi untuk mengoreksi deformitas maksilofasial pasca reposisi dan fiksasi yang mungkin hanya memerlukan tindakan touch up satu sampai dua kali saja

2021 ◽  
pp. 105566562110017
Author(s):  
Kyung Hoon Chung ◽  
Karel A. deLeeuw ◽  
Hsiu-Hsia Lin ◽  
Lun-Jou Lo

Background:There is an increasing patient expectation for better esthetics, manifesting through anatomical harmony, projection, and volume of the upper lip relative to the lower lip, in patients with cleft deformity. The aim of this study is to investigate the outcome of vermilion augmentation using autologous dermofat graft (DFG) to enhance the lip using both quantitative and qualitative assessment.Methods:Patients with secondary cleft lip deformity who received the surgical treatment in our institution from 2015 to 2018 were recruited. Panel assessment was performed on standardized preoperative and postoperative digital photographs. A patient questionnaire was used for the reported outcome. Image processing and analyses were applied to measure the lip change. Statistical analyses were performed.Results:A total of 91 patients were included. The mean age at operation was 22.7 years, and postoperative follow-up was 3.6 years. There were no complications in the study group. The panel assessment showed significant improvement ( P < .00001) on upper lip vermilion in both frontal and lateral profile views. Ninety-five percent of patients reported improvement of the upper lip projection and volume. Quantitative image analysis showed an increase in the upper lip vermilion ratio in 97% of the cases in frontal views and improvement of the vermilion projection in 87% of the cases in the superimposed lateral views.Conclusions:The use of DFG is an effective and reproducible method for vermilion augmentation and aesthetic enhancement in patients presenting with upper lip insufficiency relative to the lower lip.


1994 ◽  
Vol 11 (2) ◽  
pp. 85-90 ◽  
Author(s):  
Harold M. Reed

The evolving techniques of augmentation phalloplasty and penile autologous fat transplantation (AFT) are described, with historical correlation. Experience derived from 200 procedures is presented, relating to patient selection, informed consent, biophotography, intraoperative technique, skin transfer, and postoperative care. While total corporal length remains unchanged, an outward gain of 1 to 5 cm (average 3 cm) can be obtained. Success with simultaneous AFT has been variable, and touch-ups may be required. Complications include disappointment with “low-end” results, reabsorption of fat (zonal and complete), seen especially with smokers, emergence of fatty nodules minimized by more thorough undermining, and one case of mucosal shaft edema and hyperesthesia still in follow-up. In general, patients are pleased and thus there is encouragement to refine and continue in appropriately selected cases.


2012 ◽  
Vol 153 (46) ◽  
pp. 1816-1831 ◽  
Author(s):  
Zoltán Mátrai ◽  
Pál Pesthy ◽  
Gusztáv Gulyás ◽  
Éva Szabó ◽  
Alexandra Bartal ◽  
...  

Autologous fat transplantation is often used in aesthetic plastic surgery, and is recently becoming increasingly popular in the reconstruction of soft tissue defects following oncological surgery. A still not standardized technique of fat transplantation for breast cancer reconstruction is rapidly getting popular. The procedure is not a passive volume replacement, but transplantation of biologically active tissue bearing endocrine, paracrine, exocrine functions and containing fat-derived stem cells, which in the tumorous environment raises many questions in relation to the oncological safety and diagnostic follow-up. Although long-term results based on prospective, randomized studies are not yet available, published clinical experience is promising and reveals an effective and surgically safe procedure if used with appropriate indications and techniques. The authors conducted a broad review of the literature, presenting indications, technique, molecular interactions, and potential risks of the clinical results of autologous fat transplantation in the breast cancer reconstructive surgery. The authors initiated that breast and plastic surgeons should promote adequate long term follow-up of breast cancer patients who underwent breast reconstruction with autologous fat transplantation by the establishment of national registries. Orv. Hetil., 2012, 153, 1816–1831.


2019 ◽  
Vol 42 ◽  
Author(s):  
John P. A. Ioannidis

AbstractNeurobiology-based interventions for mental diseases and searches for useful biomarkers of treatment response have largely failed. Clinical trials should assess interventions related to environmental and social stressors, with long-term follow-up; social rather than biological endpoints; personalized outcomes; and suitable cluster, adaptive, and n-of-1 designs. Labor, education, financial, and other social/political decisions should be evaluated for their impacts on mental disease.


1999 ◽  
Vol 173 ◽  
pp. 189-192
Author(s):  
J. Tichá ◽  
M. Tichý ◽  
Z. Moravec

AbstractA long-term photographic search programme for minor planets was begun at the Kleť Observatory at the end of seventies using a 0.63-m Maksutov telescope, but with insufficient respect for long-arc follow-up astrometry. More than two thousand provisional designations were given to new Kleť discoveries. Since 1993 targeted follow-up astrometry of Kleť candidates has been performed with a 0.57-m reflector equipped with a CCD camera, and reliable orbits for many previous Kleť discoveries have been determined. The photographic programme results in more than 350 numbered minor planets credited to Kleť, one of the world's most prolific discovery sites. Nearly 50 per cent of them were numbered as a consequence of CCD follow-up observations since 1994.This brief summary describes the results of this Kleť photographic minor planet survey between 1977 and 1996. The majority of the Kleť photographic discoveries are main belt asteroids, but two Amor type asteroids and one Trojan have been found.


Author(s):  
D.G. Osborne ◽  
L.J. McCormack ◽  
M.O. Magnusson ◽  
W.S. Kiser

During a project in which regenerative changes were studied in autotransplanted canine kidneys, intranuclear crystals were seen in a small number of tubular epithelial cells. These crystalline structures were seen in the control specimens and also in regenerating specimens; the main differences being in size and number of them. The control specimens showed a few tubular epithelial cell nuclei almost completely occupied by large crystals that were not membrane bound. Subsequent follow-up biopsies of the same kidneys contained similar intranuclear crystals but of a much smaller size. Some of these nuclei contained several small crystals. The small crystals occurred at one week following transplantation and were seen even four weeks following transplantation. As time passed, the small crystals appeared to fuse to form larger crystals.


Author(s):  
C. Wolpers ◽  
R. Blaschke

Scanning microscopy was used to study the surface of human gallstones and the surface of fractures. The specimens were obtained by operation, washed with water, dried at room temperature and shadowcasted with carbon and aluminum. Most of the specimens belong to patients from a series of X-ray follow-up study, examined during the last twenty years. So it was possible to evaluate approximately the age of these gallstones and to get information on the intensity of growing and solving.Cholesterol, a group of bile pigment substances and different salts of calcium, are the main components of human gallstones. By X-ray diffraction technique, infra-red spectroscopy and by chemical analysis it was demonstrated that all three components can be found in any gallstone. In the presence of water cholesterol crystallizes in pane-like plates of the triclinic crystal system.


1979 ◽  
Vol 10 (3) ◽  
pp. 139-144
Author(s):  
Cheri L. Florance ◽  
Judith O’Keefe

A modification of the Paired-Stimuli Parent Program (Florance, 1977) was adapted for the treatment of articulatory errors of visually handicapped children. Blind high school students served as clinical aides. A discussion of treatment methodology, and the results of administrating the program to 32 children, including a two-year follow-up evaluation to measure permanence of behavior change, is presented.


2020 ◽  
Vol 29 (2) ◽  
pp. 688-704
Author(s):  
Katrina Fulcher-Rood ◽  
Anny Castilla-Earls ◽  
Jeff Higginbotham

Purpose The current investigation is a follow-up from a previous study examining child language diagnostic decision making in school-based speech-language pathologists (SLPs). The purpose of this study was to examine the SLPs' perspectives regarding the use of evidence-based practice (EBP) in their clinical work. Method Semistructured phone interviews were conducted with 25 school-based SLPs who previously participated in an earlier study by Fulcher-Rood et al. 2018). SLPs were asked questions regarding their definition of EBP, the value of research evidence, contexts in which they implement scientific literature in clinical practice, and the barriers to implementing EBP. Results SLPs' definitions of EBP differed from current definitions, in that SLPs only included the use of research findings. SLPs seem to discuss EBP as it relates to treatment and not assessment. Reported barriers to EBP implementation were insufficient time, limited funding, and restrictions from their employment setting. SLPs found it difficult to translate research findings to clinical practice. SLPs implemented external research evidence when they did not have enough clinical expertise regarding a specific client or when they needed scientific evidence to support a strategy they used. Conclusions SLPs appear to use EBP for specific reasons and not for every clinical decision they make. In addition, SLPs rely on EBP for treatment decisions and not for assessment decisions. Educational systems potentially present other challenges that need to be considered for EBP implementation. Considerations for implementation science and the research-to-practice gap are discussed.


2019 ◽  
Vol 28 (3) ◽  
pp. 1039-1052
Author(s):  
Reva M. Zimmerman ◽  
JoAnn P. Silkes ◽  
Diane L. Kendall ◽  
Irene Minkina

Purpose A significant relationship between verbal short-term memory (STM) and language performance in people with aphasia has been found across studies. However, very few studies have examined the predictive value of verbal STM in treatment outcomes. This study aims to determine if verbal STM can be used as a predictor of treatment success. Method Retrospective data from 25 people with aphasia in a larger randomized controlled trial of phonomotor treatment were analyzed. Digit and word spans from immediately pretreatment were run in multiple linear regression models to determine whether they predict magnitude of change from pre- to posttreatment and follow-up naming accuracy. Pretreatment, immediately posttreatment, and 3 months posttreatment digit and word span scores were compared to determine if they changed following a novel treatment approach. Results Verbal STM, as measured by digit and word spans, did not predict magnitude of change in naming accuracy from pre- to posttreatment nor from pretreatment to 3 months posttreatment. Furthermore, digit and word spans did not change from pre- to posttreatment or from pretreatment to 3 months posttreatment in the overall analysis. A post hoc analysis revealed that only the less impaired group showed significant changes in word span scores from pretreatment to 3 months posttreatment. Discussion The results suggest that digit and word spans do not predict treatment gains. In a less severe subsample of participants, digit and word span scores can change following phonomotor treatment; however, the overall results suggest that span scores may not change significantly. The implications of these findings are discussed within the broader purview of theoretical and empirical associations between aphasic language and verbal STM processing.


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