scholarly journals Association of Computer Tomography Features Of COVID-19 with Outcomes, Clinical and Laboratory Parameters

2021 ◽  
Vol 11 (6) ◽  
pp. 447-456
Author(s):  
A. V. Melekhov ◽  
M. A. Sayfullin ◽  
V. S. Petrovichev ◽  
A. I. Agaeva ◽  
K. Y. Golubykh ◽  
...  
Keyword(s):  
Computer Tomography ◽  
Laboratory Data ◽  
Chest Ct ◽  
Ct Scans ◽  
Chronic Obstructive ◽  
Chain Reaction ◽  
Obstructive Pulmonary Disease ◽  
Cumulative Survival ◽  
Coronavirus Infection ◽  
Novel Coronavirus

Aim: to assess the results of chest computer tomography (CT) of patients with novel coronavirus infection in correspondence with their outcomes, clinical and laboratory data. Methods: retrospective analysis of 962 chest CT scans, outcomes, clinical and laboratory data of all 354 COVID-19 patients hospitalized from April to June 2020. Results: Sensitivity and specificity of CT with polimerase chain reaction (PCR) as a reference were: 98.0 % and 5.7 % respectively; for PCR with CT as a reference: 54.6 % and 70.7 % respectively. Patients with positive and negative PCR tests had no significant differences in mean CT score and CO-RADS score. Cumulative survival was better in patients with lower CT score (significant only for maximal, not baseline scores). CT score changed during hospitalization in survived patients clinically insignificant (from 2 (1-2) to 2 (1-2), p=0.001), and increased in dead (from 2 (1,5-3) to 4 (4-4), p <0.001). Lower CT score and better survival was in females, patient younger than 59 years, with NEWS score <3, without atrial fibrillation. Diabetes mellitus and obesity was associated with higher CT score, but not with survival. Chronic obstructive pulmonary disease, coronary heart disease and chronic heart failure was associated with lower survival, but not CT score. Conclusion: chest CT significantly increases diagnostic accuracy and assessment of the prognosis in COVID-19 patients.

scholarly journals Management of patients with comorbidity during novel coronavirus (COVID-19) pandemic. National Consensus Statement 2020

2020 ◽  
Vol 19 (4) ◽  
pp. 2630 ◽  
Author(s):  
V. B. Grinevich ◽  
I. V. Gubonina ◽  
V. L. Doshchitsin ◽  
Yu. V. Kotovskaya ◽  
Yu. A. Kravchuk ◽  
...  
Keyword(s):  
Gastrointestinal Disease ◽  
Multiple Organ ◽  
Adverse Outcomes ◽  
Chronic Obstructive ◽  
The Novel ◽  
Vulnerable Group ◽  
Obstructive Pulmonary Disease ◽  
Medical Facilities ◽  
Coronavirus Infection ◽  
Novel Coronavirus

The pandemic of the novel coronavirus infection (COVID-19), caused by SARS‑CoV‑2, has become a challenge to healthcare systems in all countries of the world. Patients with comorbidity are the most vulnerable group with the high risk of adverse outcomes. The problem of managing these patients in context of a pandemic requires a comprehensive approach aimed both at the optimal management in self-isolated patients not visiting medical facilities, and management of comorbidities in patients with COVID-19. The presented consensus covers these two aspects of managing patients with cardiovascular disease, diabetes, chronic obstructive pulmonary disease, gastrointestinal disease, and also pay attention to the multiple organ complications of COVID-19.

Clinical, Radiological and Laboratory Profile of Covid-19 Patients Admitted to a Dedicated Covid-19 Hospital in Odisha

2021 ◽  
Vol 8 (15) ◽  
pp. 989-993
Author(s):  
Mohan Rao C ◽  
Nipa Singh ◽  
Kinshuk Sarbhai ◽  
Saswat Subhankar ◽  
Sanghamitra Pati ◽  
...  
Keyword(s):  
Laboratory Data ◽  
Ct Images ◽  
The State ◽  
Viral Clearance ◽  
Clinical Profile ◽  
Chronic Obstructive ◽  
Laboratory Findings ◽  
Obstructive Pulmonary Disease ◽  
Reactive Protein ◽  
Set Up

BACKGROUND The Covid-19 pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a public health challenge being faced by the world currently. International and national responses to combat the Covid-19 pandemic have been very prompt with the setting up of dedicated Covid-19 hospitals. In the state of Odisha, situated in the eastern part of India, Kalinga Institute of Medical Sciences (KIMS), set up the first dedicated Covid hospital of the state. This study intends to chronicle the clinical profile, radiological presentations, laboratory findings, and clinical outcome of patients admitted to the KIMS Covid hospital. METHODS A retrospective analysis of the clinical and laboratory data of patients admitted with Covid-19 diagnosis at the dedicated Covid-19 hospital from 5th April 2020 to 4th June 2020 was done. RESULTS A total number of 272 Covid-19 cases were included in this study. Majority of the patients were males (83.57 %) and most of the patients (79.04 %) were asymptomatic. The mortality rate was 1.9 %. Fever (18.38 %), cough (17.27 %), dyspnoea (16.91 %) and myalgia (14.7 %) were the major symptoms observed. Severity was mild in 78.94 % cases. Delayed viral clearance was seen in 13 % cases. The typical features of novel SARS-CoV-2 infection was seen in 12 - 13 % cases in computed tomography (CT) images of thorax. c-reactive protein (CRP) was raised as a biomarker of inflammation. Of the 5 deaths encountered, 2 had diabetes mellitus, 2 were hypertensive and 1 had chronic obstructive pulmonary disease (COPD). CONCLUSIONS Covid-19 may have a delayed viral clearance beyond two weeks. A discordance between CT images and the clinical condition may also be observed. Diabetes, hypertension, and high blood CRP levels were significantly associated with mortality. KEYWORDS Covid-19, SARS-CoV-2, Clinical Profile, Radiological Findings, Comorbidities, Fatality

Main bronchial diverticula in the subcarinal region: Their relation to airflow limitations

2012 ◽  
Vol 53 (1) ◽  
pp. 44-48 ◽  
Author(s):  
Takeshi Higuchi ◽  
Naoya Takahashi ◽  
Motoi Shiotani ◽  
Suguru Sato ◽  
Atsushi Ohta ◽  
...  
Keyword(s):  
Thin Section ◽  
Pathological Condition ◽  
Chest Ct ◽  
Pulmonary Diseases ◽  
Chronic Obstructive ◽  
Study Group ◽  
Obstructive Pulmonary Disease ◽  
Student’S T ◽  
The Relationship ◽  
Student’S T Test

Background To date, bronchial diverticula have generally been treated as a pathological condition associated with chronic obstructive pulmonary disease (COPD), although only a limited amount of published information is available on the relationship between bronchial diverticula as depicted by multidetector computed tomography (MDCT) and airflow limitations. Purpose To evaluate the relationship between airflow limitations and main bronchial diverticula in the subcarinal region using spirometry and thin-section MDCT. Material and Methods A total of 189 consecutive adult patients were retrospectively evaluated based on spirometry and thin-section MDCT of the chest. All examinations were performed at our institution between June and October 2008. The study group included 70 women and 119 men with a mean age of 65 years (range 19–86 years). The relationship between the FEV1% and bronchial diverticula in the subcarinal region was analyzed (Student's t-test). Results The indications for conducting the examinations were pulmonary diseases (82 patients), cardiovascular diseases (22), extrapulmonary malignancies (74), and other conditions (11). A total of 84/189 (44.4%) patients showed bronchial diverticula, and the FEV1% of 70/84 (83.3%) patients was above 70. The FEV1% of patients with lesions ranged from 26.0 to 97.8 (mean 76.8), whereas the range was 28.1–94.4 (mean 73.7) in those without lesions. There was no significant association between the FEV1% and the presence of subcarinal bronchial diverticula ( P > 0.05). Conclusion Our data demonstrate that thin-section chest CT commonly demonstrates main bronchial diverticula in the subcarinal region in patients without airflow limitations. We propose that the presence of a small number of tiny bronchial diverticula under the carina may not be a criterion for the diagnosis of COPD.

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