scholarly journals Magnetic-lazer modulation of specific humoral immunity in pregnant women with anemia

2011 ◽  
Vol 10 (3) ◽  
pp. 149-154
Author(s):  
S. Yu. Yuriyev ◽  
I. V. Aristova ◽  
Ye. F. Levitsky ◽  
S. S. Shakhova ◽  
S. A. Krotov
Keyword(s):  
Helicobacter Pylori ◽  
Comparative Analysis ◽  
Gastrointestinal Tract ◽  
Pregnant Women ◽  
Humoral Immunity ◽  
Cellular Immunity ◽  
Humoral And Cellular Immunity ◽  
Mild Anemia ◽  
Laser Effect ◽  
Stimulation Of

This article presents the comparative analysis of humoral and cellular immunity indicators under the influence of magneticlaser effect in 2 frequency ranges (150—1 5000 Hz) for treatment of pregnant women with mild anemia against the background of chronic gastritis, associated with contamination gastrointestinal tract Helicobacter pylori. The application of magnetic-laser effect in frequency 150 Hz allows to raise of hemoglobin lowers the titre of antibodies to Helicobacter pylori. The moderate stimulation of Th1 link withoit activation of humoral immunity is optimal in treatment of benign anemia of pregnancy.

Humoral and cellular immunity in HIV positive and HIV negative Helicobacter pylori infected patients

1993 ◽  
Vol 280 (1-2) ◽  
pp. 186-196 ◽  
Author(s):  
Jutta Benz ◽  
Hilde Hasbach ◽  
Martina Brenden ◽  
Sebastian Eidt ◽  
Gerhard Fätkenheuer ◽  
...  
Keyword(s):  
Helicobacter Pylori ◽  
Cellular Immunity ◽  
Hiv Positive ◽  
Humoral And Cellular Immunity ◽  
Hiv Negative

Functional indicators of humoral and cellular immunity in viral infectionsin vivo: A comparative analysis

1995 ◽  
Vol 120 (6) ◽  
pp. 1214-1216
Author(s):  
V. V. Makarov ◽  
I. F. Vishnyakov ◽  
A. A. Kolomytsev ◽  
A. D. Sereda
Keyword(s):  
Comparative Analysis ◽  
Cellular Immunity ◽  
Humoral And Cellular Immunity

scholarly journals The magnetic-laser therapy in the system treatment of anemia in pregnant women infected with Helicobacter pylori

2010 ◽  
Vol 9 (1) ◽  
pp. 91-96
Author(s):  
I. V. Aristova ◽  
S. Yu. Yuriyev ◽  
L. V. Barabash ◽  
S. A. Krotov
Keyword(s):  
Helicobacter Pylori ◽  
Gastrointestinal Tract ◽  
Pregnant Women ◽  
Laser Therapy ◽  
Chronic Gastritis ◽  
Clinical Effect ◽  
Infectious Process ◽  
Results Of Treatment ◽  
Laser Impact ◽  
Magnetic Laser Therapy

The article is presented with the results of comparing assessment of clinical efficiency of the magnetic-laser therapy in doublefrequency ranges (150 ang 1 500 Hz) combined with iron therapy (sorbifer 100 mg once a day) in treatment of benign anemia of pregnancy, running above with the chronic gastritis, associated with contamination of gastrointestinal tract by Helicobacter pylori. The results of treatment show that the clinical effect is optimal for noninvasive magnetic-laser impact on blood with 150 Hz frequency. This method allows to raise hemoglobin while maintaining the iron depot in the form of ferritin together with cutting off the infectious process on the gastrointestinal tract mucous.

scholarly journals Abortion pregnant: immunologycal and gormonale aspects

2002 ◽  
Vol 51 (2) ◽  
pp. 28-32
Author(s):  
L. A. Samorodinova ◽  
T. L. Kormakowa
Keyword(s):  
Pregnant Women ◽  
Cellular Immunity ◽  
Immune Status ◽  
Considerable Reduction ◽  
Placental Lactogen ◽  
Suppressor Activity ◽  
Humoral And Cellular Immunity ◽  
Period Of Gestation

The object of the research is to study the condition of humoral and cellular immunity of pregnant women with imminent and incipient abortion, as well as study the gormonal function of suncitiotrophoblasts. The study of immune status of pregnant with abortion showed the considerable reduction of suppressor activity and increase of the activity jf immunity helper unit. After the completion of therapy, increase in suppressor activity was mentioned, as well as approach of laboratory figures to the ones of healthy pregnant women. The study revealed quick reduction of placental lactogen and beta-trophoblastic globulin of pregnant with abortion, retention of low figures of these hormones during the whole period of gestation process. These data should be considered as the appearance of placental deficiency.

Host Immune Responses Against CT Antigens in Multiple Myeloma Patients.

Blood ◽  
2006 ◽  
Vol 108 (11) ◽  
pp. 3492-3492 ◽  
Author(s):  
Nikoletta Lendvai ◽  
Sacha Gnjatic ◽  
Erika Ritter ◽  
Yao-Tseng Chen ◽  
Christina Coughlin ◽  
...  
Keyword(s):  
Multiple Myeloma ◽  
Bone Marrow ◽  
Immune Responses ◽  
Humoral Immunity ◽  
Cellular Immunity ◽  
Therapeutic Vaccine ◽  
Type I ◽  
Humoral And Cellular Immunity ◽  
Ct Antigen ◽  
Ct Antigens

Abstract The type I Melanoma Antigen GEne (MAGE) proteins belong to the Cancer-Testis (CT) family of tumor-associated antigens and are widely expressed in solid and hematologic malignancies. They are immunogenic and frequently elicit spontaneous immune responses in patients with CT antigen-expressing tumors, particularly in malignant melanoma. In melanoma patients, there is high concordance between humoral and cellular immunity. Based on these findings, CT antigens are widely investigated as potential antigenic targets for tumor-specific therapeutic vaccines. We previously showed that the type I MAGE proteins CT7 (MAGE-C1), CT10 (MAGE-C2) and MAGE-A3 were commonly detected in primary myeloma specimens, and expression of CT7 and MAGE-A3 was correlated with abnormally elevated plasma cell proliferation. These findings suggest that type I MAGE may be rational targets for vaccine therapy in multiple myeloma. Therefore, it is important to determine if type I MAGE elicit cellular or humoral immune responses in myeloma patients. To investigate this hypothesis, we assessed cellular immunity against CT7 and humoral immunity against a broad panel of CT antigens. To quantify CT7-specific cellular immunity, expanded, polyclonal pools of T cells from the bone marrow, the tumor microenvironment, were co-cultured in interferon gamma (IFNγ) ELISpot assays with autologous antigen-presenting cells (APC) transduced with in vitro transcribed mRNA coding for CT7 or control antigens. CT antigen-specific humoral immunity was examined by ELISA assay using patient serum or plasma and recombinant CT antigens. This analysis demonstrated that 2/9 patients exhibited specific T cell immunity against CT7 in their bone marrow lymphocytes as measured by IFNγ secretion. These same two patients had positive titers for other CT antigens; one for MAGE-A1 (another type I MAGE), the other for SSX-1 (a structurally distinct CT antigen). Interestingly, neither patient had positive serology for CT7. Serum from 16 other myeloma patients did not have detectible antibody titers for a broad panel of CT antigens. These results show that CT antigens are immunogenic in myeloma patients, with cellular responses against CT7 and humoral responses against MAGE-A1 and SSX-1. However, unlike other types of cancer, there appears to be discordance between humoral and cellular immunity against CT7 in multiple myeloma. This may be due in part to the significant derangements of humoral immunity in this disease. These results support further investigation of immunologic therapies targeting type I MAGE in myeloma, especially therapeutic vaccine strategies.

scholarly journals Impact of Preexisting Vector-Specific Immunity on Vaccine Potency: Characterization of Listeria monocytogenes-Specific Humoral and Cellular Immunity in Humans and Modeling Studies Using Recombinant Vaccines in Mice

2009 ◽  
Vol 77 (9) ◽  
pp. 3958-3968 ◽  
Author(s):  
Meredith L. Leong ◽  
Johannes Hampl ◽  
Weiqun Liu ◽  
Shruti Mathur ◽  
Keith S. Bahjat ◽  
...  
Keyword(s):  
Listeria Monocytogenes ◽  
Humoral Immunity ◽  
Cellular Immunity ◽  
High Titer ◽  
Listeriolysin O ◽  
Wild Type ◽  
Vaccine Platform ◽  
Humoral And Cellular Immunity ◽  
Specific Immunity ◽  
Modeling Studies

ABSTRACT Recombinant live-attenuated Listeria monocytogenes is currently being developed as a vaccine platform for treatment or prevention of malignant and infectious diseases. The effectiveness of complex biologic vaccines, such as recombinant viral and bacterial vectors, can be limited by either preexisting or vaccine-induced vector-specific immunity. We characterized the level of L. monocytogenes-specific cellular and humoral immunity present in more than 70 healthy adult subjects as a first step to understanding its possible impact on the efficacy of L. monocytogenes-based vaccines being evaluated in early-phase clinical trials. Significant L. monocytogenes-specific humoral immunity was not measured in humans, consistent with a lack of antibodies in mice immunized with wild-type L. monocytogenes. Cellular immune responses specific for listeriolysin O, a secreted bacterial protein required for potency of L. monocytogenes-derived vaccines, were detected in approximately 60% of human donors tested. In mice, while wild-type L. monocytogenes did not induce significant humoral immunity, attenuated L. monocytogenes vaccine strains induced high-titer L. monocytogenes-specific antibodies when given at high doses used for immunization. Passive transfer of L. monocytogenes-specific antiserum to naïve mice had no impact on priming antigen-specific immunity in mice immunized with a recombinant L. monocytogenes vaccine. In mice with preexisting L. monocytogenes-specific immunity, priming of naïve T cells was not prevented, and antigen-specific responses could be boosted by additional vaccinations. For the first time, our findings establish the level of L. monocytogenes-specific cellular immunity in healthy adults, and, together with modeling studies performed with mice, they support the scientific rationale for repeated L. monocytogenes vaccine immunization regimens to elicit a desired therapeutic effect.

Stimulation of Humoral and Cellular Immunity by Viscum Preparations

Planta Medica ◽  
1982 ◽  
Vol 46 (12) ◽  
pp. 221-227 ◽  
Author(s):  
N. Bloksma ◽  
P. Schmiermann ◽  
M. de Reuver ◽  
H. van Dijk ◽  
J. Willers
Keyword(s):  
Cellular Immunity ◽  
Humoral And Cellular Immunity ◽  
Stimulation Of

scholarly journals Humoral and Cellular Immunity in Children with Mycoplasma pneumoniae Infection: a 1-Year Prospective Study

2005 ◽  
Vol 12 (10) ◽  
pp. 1246-1250 ◽  
Author(s):  
Iwona Stelmach ◽  
Malgorzata Podsiadłowicz-Borzęcka ◽  
Tomasz Grzelewski ◽  
Pawel Majak ◽  
Wlodzimierz Stelmach ◽  
...  
Keyword(s):  
Prospective Study ◽  
Mycoplasma Pneumoniae ◽  
Humoral Immunity ◽  
Cellular Immunity ◽  
Immunoglobulin G ◽  
Serum Immunoglobulin ◽  
Humoral And Cellular Immunity ◽  
Cellular And Humoral Immunity ◽  
Lymphocyte Phenotypes ◽  
Mycoplasma Pneumoniae Infection

ABSTRACT To determine whether children have persistent abnormalities in cellular and humoral immunity development after acute Mycoplasma pneumoniae infection, serum immunoglobulin G (IgG), IgA, IgM, and IgE levels and lymphocyte phenotypes were determined. There were no changes in the levels of IgG, IgM, IgA, or CD4+ or CD19+ lymphocytes that were measured in M. pneumoniae-positive patients after 3 months or after 12 months, but there were increases in these in M. pneumoniae-negative patients. Serum IgE increased in M. pneumoniae-positive patients. We have shown alterations in immunity development after M. pneumoniae infection.

scholarly journals EVALUATION OF HUMORAL IMMUNITY IN PREGNANT WOMEN WITH ALLERGIC HISTORY

2013 ◽  
Vol 10 (6) ◽  
pp. 75-82
Author(s):  
S N Denisova ◽  
M Yu Belitskaya ◽  
T B Sentsova ◽  
S V Bogdanova
Keyword(s):  
New Zealand ◽  
Gastrointestinal Tract ◽  
Pregnant Women ◽  
Humoral Immunity ◽  
Comparison Group ◽  
Goat Milk ◽  
Cow’S Milk ◽  
Ige Antibodies ◽  
Total Ige ◽  
Cow's Milk

Background. The aim of the study was to evaluate humoral immunity and efficacy of diet therapy in pregnant women with allergic history. Methods. Monitoring group comprised 118 pregnant women. The study group included 83 pregnant women who received dietary correction of the diet with the inclusion of the New Zealand goat milk. The comparison group consisted of 35 pregnant women, dietary recommendations, with the inclusion in the diet of the cow’s milk (CM). The content of total serum IgE was detected using the immunoassay analyzer using monospecific reagent. Allergenspecific IgE antibodies to CM, βLH, casein and soy protein were determined by enzyme immunoassay analyzer using commercial kits «Allergopharma». Contents of immunoglobulins G, A, M in the serum were determined by nephelometry on immunochemical analyzer IMMAGE. Results. Unlike women from the comparison group half of pregnant women had a core group of allergic diseases, the majority of women in both groups were observed burdened obstetric history, indicating a decrease in their reproductive function. Dysfunctions of the gastrointestinal tract were observed in 34,7% of pregnant women in both groups, and the frequency in women with an allergy was 2,3 times higher than in women not suffering from allergic reactions. High levels of total IgE in serum were observed in the patients with allergy, diseases of the gastrointestinal tract, as well as their combination. The concentration of allergen specific IgE antibodies to proteins in cow’s milk was higher in women with IgEmediated allergies. In pregnant women with allergies and diseases of the gastrointestinal tract serum IgG and IgA levels were decreased. Conclusion. Application of hypoallergenic diet with cow’s milk replacement for New Zealand goat milk, as well as the exclusion of cow’s milk or a restriction in the diet of pregnant women caused a reduction of total IgE in the blood compared to previous treatment. Allergenspecific IgE antibodies to milk proteins decreased in the majority of women while dietary treatment.

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