scholarly journals MODERN STATE OF THE PROBLEM OF DIAGNOSIS OF THYROID NODULES (LITERATURE REVIEW)

2018 ◽  
Vol 43 ◽  
Author(s):  
Diyor Shukurullaevich Abdurakhmanov ◽  
◽  
Jasur Zafarovich Shamsiev ◽  
BMC Surgery ◽  
2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Yu Min ◽  
Hang Chen ◽  
Xing Wang ◽  
Ying Huang ◽  
Guobing Yin

Abstract Background Horner syndrome (HS), mainly characterized by symptoms including ptosis, miosis, and anhidrosis on the affected face, is a condition that is well documented but rarely reported as a postoperative complication of thyroidectomy, particularly in endoscopic thyroid surgery (ETS). We hereby report a case of HS due to ETS with a brief literature review on this topic. Case presentation A 31-year-old female was admitted to our hospital with an unexpected physical examination finding of two thyroid nodules that were hypoechoic, had an irregular shape, and exhibited calcification. Subsequently, the results of a fine-needle aspiration (FNA) biopsy from the thyroid nodules and BRAFV600E mutation further confirmed the malignancy of these nodules. Thus, total thyroidectomy combined with central lymph node dissection (CLND) by ETS via the bilateral axillo-breast approach was performed on this patient. Histology confirmed the diagnosis of papillary thyroid microcarcinoma (PTMC) concurrent with Hashimoto’s thyroiditis (HT). However, this patient developed HS with ptosis in her left eye on postoperative day 3. All symptoms gradually resolved before the 3-month follow-up. Conclusion HS subsequent to ETS is a rare complication. Thus, standardized and appropriate operative procedures, as well as subtle manipulation, are essential in preventing and reducing the occurrence of HS. In addition, the early diagnosis and management of this rare complication are also important for a favorable outcome.


2020 ◽  
Vol 162 (5) ◽  
pp. 634-640 ◽  
Author(s):  
Amy Vora ◽  
Shelby Holt ◽  
Wasim Haque ◽  
Ildiko Lingvay

Objective To assess outcomes of thyroid nodules analyzed with the AFIRMA gene expression classifier (GEC) and to perform a comprehensive literature review. Study Design Retrospective analysis of patients with thyroid nodules who underwent AFIRMA GEC testing at our institution. Settings A tertiary care academic institution. Subjects and Methods We collected clinical outcomes for 416 thyroid nodules that were analyzed with AFIRMA GEC between 2011 and 2015, including long-term follow-up through 2019. We performed a comprehensive literature review. Results The resection rate for nodules with “suspicious” GEC results was 85% with a positive predictive value of 37%. The resection rate for nodules with “benign” GEC results was 24% with a negative predictive value of 90%. The prevalence of thyroid malignancy in patients with thyroid nodules with indeterminate cytology at our institution during this timeframe was 41%, thus lowering our negative predictive value. Mean follow-up duration for unresected nodules was 27.8 months. Our resection rates for nodules with “benign” GEC were among the highest reported in the literature. Conclusions Molecular marker testing of thyroid nodules with indeterminate cytology can aid in the surgical decision making by obviating the need for diagnostic surgery and/or guiding extent of resection. Patients with other indications for surgery may not benefit from such costly testing.


Medievalia ◽  
2021 ◽  
Vol 53 (1) ◽  
pp. 25-63
Author(s):  
Rogerio R. Tostes

The present article recovers the historiographic and critical-textual discussion about the beginning of the Usatges de Barcelona. This literature review includes an examination about the dating hypotheses, interpretations on the code compilations, in addition to exploring the relationships of codes sources, with some notes on its typology, and the historical context of its formation and diffusion between the 12th-13th Centuries. It also aims to consider the role played by Usatgesas the foundation (be it true or idealized) of a publicist tradition that started in medieval Catalonia. With this approach it is possible to link all these elements assuming that many of the interpretative matrices found in its historiography are going beyond to the mere description of the sources. Finally, the paper it also deals with the institutionalist narratives that emphasize the formation of public power and the modern State.


2014 ◽  
Vol 119 (7) ◽  
pp. 512-520 ◽  
Author(s):  
Irene Chiara De Bernardi ◽  
Chiara Floridi ◽  
Alessandra Muollo ◽  
Roberta Giacchero ◽  
Gian Lorenzo Dionigi ◽  
...  

2021 ◽  
Vol 3 (1) ◽  
pp. 50
Author(s):  
Grace Sharon

Based on the provisions in the 1945 Constitution article 1 paragraph 3 which states the State of Indonesia is a state based on law, it brings the consequence that every government action must always be based on the law. From another point of view related to the development of the 21st century, the State is often said to have developed into a modern state. Whereas the state's tasks, which were initially very limited, have become increasingly widespread. This is due to the increasing needs of modern humans and especially those related to the interests of life together. Regarding the social dynamics that occur in the community, licensing arrangements are needed. A license as a one-sided government action is a stipulation arising from the strategies and techniques used by the Government to control or control various conditions or activities carried out by the community. In other words, licensing is very much needed as an instrument of community guidance. However, the author limits the scope of research on licensing only to the nature of the authority of the permit, so that the author's research in this article is done through a literature review.


2021 ◽  
Vol 102 (2) ◽  
pp. 206-215
Author(s):  
A P Ziganshina ◽  
A R Gosmanov

Still very active COVID-19 pandemic demands continuous adjustment of our regular practices of delivering patient care. The aim of this manuscript is to provide practical suggestions for the management of the most common endocrinological conditions during ongoing COVID-19/SARS-CoV2 pandemic. We have conducted a literature review and present our own experience of treating endocrinology patients during the months of full COVID-19 lockdown and then phased partial reopening. The results of the literature review have demonstrated the utmost importance of excelling in a challenging task of maintaining the best possible control of such endocrinological conditions as diabetes mellitus and adrenal insufficiency, while also maintaining the universal social distancing and isolation. In the patients with diabetes mellitus Hemoglobin A1C level correlates with the risk of unfavorable outcomes of COVID-19 which makes optimization of diabetes mellitus control an even more significant during the pandemic. It is important to provide the patients with the specific instructions on self-titration of insulin and on the use of non-insulin antidiabetic medications, examples of which are shown in the manuscript. For the patients with adrenal insufficiency, it is essential to discuss the rules of dose increase of the glucocorticosteroids in case of development of COVID-19 or any other acute illness. The diagnosis and management of other endocrinological conditions as for example thyroid nodules and osteoporosis (with the exclusion of secondary osteoporosis associated with diseases requiring timely treatment) can be delayed for the sake of everybodys safety and partially also for prioritization of healthcare recourses utilization during these uneasy times. Since the beginning of the pandemic a considerable amount of new information regarding theoretical and practical aspects of connection of SARS-CoV2 and endocrinology is emerging almost weekly. In this manuscript, we have tried to gather the most clinically relevant data on the outpatient management of the patients with endocrine pathology.


Sign in / Sign up

Export Citation Format

Share Document