scholarly journals Epidemiologic and Histopathologic Feature of Lung Cancer in Central Iran (2012-2018)

2020 ◽  
Author(s):  
Mohammad Sadegh Khalilian ◽  
Sina Narrei ◽  
Mahdi Hadian ◽  
Mehrdad Zeinalian
Keyword(s):  
Lung Cancer ◽  
Cancer Patients ◽  
Stage Iv ◽  
Developed Countries ◽  
Cross Sectional Study ◽  
Central Iran ◽  
Cancer Center ◽  
Molecular Testing ◽  
Cross Sectional ◽  
Lung Cancer Patients

Background: Lung cancer is one of the common causes of death worldwide. Although the incidence rate of lung cancer in Western countries is decreasing, it presents a growing trend in developed countries. Since there is no accurate enough information about the epidemiological and Histopathologic features of lung cancer in central Iran, Isfahan, we were motivated to conduct this research. Materials and Methods: This was a descriptive, cross-sectional study carried out in central Iran, Isfahan. All demographic, histopathological and clinical data of the lung cancer patients registered in MACSA, a referral charity-based cancer center in central Iran, was analyzed within 2012-2018 using SPSS v.22 software. Results: Altogether 260 patients with lung cancer were included in this study from 6127 cancer patients registered within 2012-2018 (4.2%). Out of them, 66.2% were men, and 18.8 % of the patients were alive at the time of the study. The mean age of the patients at diagnosis was 61.56 (SD=14.11, range: 9-93). Altogether, 63.1% of patients had metastasis of whom 57.6% were in stage IV at diagnosis. The Frequency of different types of lung cancer was 36.9% adenocarcinomas, 14.2% squamous cell carcinoma, 9.6% bronchogenic carcinoma and 8.1% small cell lung cancer, respectively. Altogether, 128 cases were smokers with an average 35.45 ± 14 pack- years. Only in 36.2% of the patients, the diagnostic and therapeutic biomarkers had been checked, and CK7 was positive in 88.9% of the cases in which the biomarker had been checked. Conclusion: Despite to similar Iranian studies, the most common histopathologic type of lung cancer among the patients was adenocarcinoma that it may be attributed to the lower consumption of smoking in our population and their different genetic context. Molecular biomarkers had been checked in a small portion of the patients. More education of the clinicians along with the development of cancer molecular testing may lead to promote the personalized-based approach.

Psychological correlates of sleep quality in lung cancer patients under chemotherapy: A single‐center cross‐sectional study

2019 ◽  
Vol 28 (9) ◽  
pp. 1879-1886 ◽  
Author(s):  
Dimitrios Papadopoulos ◽  
Maria Kiagia ◽  
Andriani Charpidou ◽  
Ioannis Gkiozos ◽  
Konstantinos Syrigos
Keyword(s):  
Lung Cancer ◽  
Sleep Quality ◽  
Cancer Patients ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Single Center ◽  
Cross Sectional ◽  
Lung Cancer Patients ◽  
Psychological Correlates

scholarly journals Disability among lung cancer patients and its predictors: a cross-sectional study in a tertiary care centre at Kolkata, India

2019 ◽  
Vol 7 (7) ◽  
pp. 2775
Author(s):  
Jayita Pal ◽  
Avradip Santra
Keyword(s):  
Lung Cancer ◽  
Cancer Patients ◽  
Tertiary Care ◽  
Cross Sectional Study ◽  
Care Centre ◽  
Sectional Study ◽  
Tertiary Care Centre ◽  
Cross Sectional ◽  
Lung Cancer Patients ◽  
Degree Of Disability

Background: Lung cancer is one of the commonest cancer worldwide and also in India. Being a chronic disease, it is expected to result in disability during the course of the illness. Disability in turn results in deterioration of mental health and leads to poor quality of life. The present study intended to assess the degree of disability among lung cancer patients and to find out the covariates of the same.Methods: An institution based cross-sectional study had been conducted over a period of six months among lung cancer patients attending a tertiary care centre. Exit interview had been conducted with a pretested schedule after taking informed consent. Disability had been assessed by WHO Disability Assessment Schedule 2.0 (WHODAS 2.0). Data were entered and analysed in SPSS 20.0 version.Results: A total of 210 patients were recruited in this study. Half of the study population were suffering from higher level of disability. Multivariate analysis revealed degree of disability was higher among the patients who were financially dependent to others, had advanced stage of the disease and when time since diagnosis was more than one month.Conclusions: Holistic approach needs to be taken up to address this alarming issue of disability and its consequences among lung cancer patients. The approach should include various rehabilitative measures, social security schemes by the government and active involvement of non-governmental organisations.

scholarly journals A cross sectional study to determine the prevalence of cough and its impact in patients with lung cancer: a patient unmet need

BMC Cancer ◽  
2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Amélie Harle ◽  
Alex Molassiotis ◽  
Oliver Buffin ◽  
Jack Burnham ◽  
Jaclyn Smith ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Cancer Patients ◽  
Smoking Status ◽  
Unmet Need ◽  
Cross Sectional Study ◽  
Common Symptom ◽  
Sectional Study ◽  
Cross Sectional ◽  
Lung Cancer Patients ◽  
The Impact

Abstract Background There is absence of literature related to cough prevalence and its characteristics in lung cancer patients, with information deriving only from broader symptoms occurrence studies. The aims of this study were to provide a snapshot of the prevalence of all-cause-cough in lung cancer patients and to characterise cough in terms of its impact and severity. Methods A cross-sectional study recruiting consecutive lung cancer patients over a pre-defined period of time and using cough-specific validated tools in a tertiary referral centre in the UK, including a cough severity VAS and the Manchester Cough in Lung Cancer scale (MCLCS). Results Data was collected from 202 patients. All-cause cough prevalence was 57% (through VAS) both in the screened (N = 223) and research (N = 202) population or 67% (through the MCLCS), and cough severity was moderate at a mean of 32 mm (in a 100 mm VAS). Age, sex, smoking status, lung cancer histology, stage and comorbidities were not associated with cough prevalence. The only variable associated with lower cough reports was being ‘on anticancer treatment’; fewer patients on treatment reported a cough (40%) compared to those off treatment (54%) (p = 0.04). The impact of cough (as measured by MCLCS) was also significant (mean score = 22). About 18% of patients felt moderate/severe distress from their cough and about 15% often or always reported disturbed sleep due to coughing. Half the patients felt their cough warranted treatment. Conclusions Cough is a common symptom in lung cancer with considerable impact on patients’ lives. Cough presence and severity should regularly be assessed in clinical practice. There is an urgent need to focus on developing more potent antitussive treatments and improve the management of this complex and distressing symptom.

scholarly journals Psychological Characteristics of Lung Cancer Patients During the 2019 Novel Coronavirus Outbreak: A Cross-Sectional and Longitudinal Study Based on a Propensity Score-Matched Population

2021 ◽  
Author(s):  
Kai Qian ◽  
Yi Deng ◽  
Yun Chen ◽  
Hao Peng ◽  
Li-Hong Jiang
Keyword(s):  
Lung Cancer ◽  
Longitudinal Study ◽  
Propensity Score ◽  
Cancer Patients ◽  
Cross Sectional Study ◽  
Education Level ◽  
Psychological Characteristics ◽  
Sectional Study ◽  
Cross Sectional ◽  
Lung Cancer Patients

Abstract Objective: This study sought to reveale the psychological characteristics of lung cancer patients at different time points of the COVID-19 epidemic. Methods: This cross-sectional study used data from two different regional medical centers. 128 pairs of lung cancer (LC) patients and non-lung cancer subjects (NLC) were selected through propensity score matching (PSM) analysis. For the longitudinal study, the anxiety and distress state before and during the COVID-19 pandemic were surveyed through a dedicated questionnaire. Results: A total of 135 LC patients and 165 healthy individuals were included in this cross-sectional study. After PSM analysis, 128 pairs of LC patients and NLC were matched and compared in this analysis. During the uptrend period of COVID-19 epidemic, there were significant differences in anxiety between LC patients and NLC (P=0.005). For LC patients, the proportions of severe distress differed significantly between the uptrend and the decline period (22.05% vs 11.90%, P=0.032). In two-way repeated ANOVA analysis, no significant main effect for group or group × condition interaction effect has been founded. The distress of LC patients is mainly manifested as worry. Logistic regression showed that gender (OR=41.48, 95% CI: 9.74-17.97), age (OR=0.20, 95% CI: 0.08-0.50), and education level (OR=4.82, 95% CI: 1.98-11.69) were correlated with “worry” and contributed significantly to the model. Conclusions: This study revealed that lung cancer patients had significant anxiety and distress during the uptrend period of the COVID-19 epidemic. The distress states of LC patients mainly manifested as worry, which was associated with age, gender, and education level.

A cross-sectional study examining the expression of splice variants K-RAS4A and K-RAS4B in advanced non-small-cell lung cancer patients

Lung Cancer ◽  
2018 ◽  
Vol 116 ◽  
pp. 7-14
Author(s):  
Veronica Aran ◽  
Pedro Masson Domingues ◽  
Fabiane Carvalho de Macedo ◽  
Carlos Augusto Moreira de Sousa ◽  
Tatiane Caldas Montella ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Small Cell Lung Cancer ◽  
Cancer Patients ◽  
Splice Variants ◽  
Cross Sectional Study ◽  
Small Cell ◽  
Sectional Study ◽  
Small Cell Lung ◽  
Cross Sectional ◽  
Lung Cancer Patients

Depression in lung cancer patients: A nationwide analysis.

2019 ◽  
Vol 37 (31_suppl) ◽  
pp. 83-83
Author(s):  
Arya Mariam Roy ◽  
Manojna Konda ◽  
Aravind Mohanakumar Warrier ◽  
Konstantinos Arnaoutakis
Keyword(s):  
Quality Of Life ◽  
Lung Cancer ◽  
Cancer Patients ◽  
Average Length ◽  
Malignant Neoplasm ◽  
Cross Sectional Study ◽  
Principal Diagnosis ◽  
Cross Sectional ◽  
Lung Cancer Patients

83 Background: Depression is a major ongoing problem with cancer patients and survivors. Depression can lead to functional impairment, decreased utilization of treatment, decreased quality of life and increased suicide risk. It also leads to an extended hospital stay and increased cost of treatment. Previous studies have shown that lung cancer has a high incidence for depression. Methods: We conducted a cross-sectional study using the National Inpatient Sample (NIS) database for the year 2016. Patients who were admitted with a principal diagnosis of Malignant Neoplasm of Bronchus and Lung (MNBL) and Major Depressive Disorder (MDD) were identified using ICD-10 codes. The prevalence of MDD and the risk factors contributing to MDD were studied. Statistical analysis was performed using STATA tool and tested with Pierson Chi-Square test. Results: A total of 79096 hospitalizations with a principal diagnosis of MNBL were identified. The prevalence of depression among lung cancer patients was found to be 12.49% (n = 9881). The mean age of lung cancer patients with depression was 62.27 ± 0.10. Females with lung cancer have more risk for MDD (15%, p < 0.001). Caucasian patients with lung cancer have a higher risk of MDD (13.6%, p < 0.001). It was also found that lung cancer patients who are ≤ 55 years have a higher risk of MDD (p < 0.001). The average length of stay for lung cancer patients with MDD was slightly higher than lung cancer patients without MDD (6.39 days and 5.99 days respectively). The average cost of stay also had a similar pattern. Severe morbidity was seen in a greater proportion of the MDD group. Conclusions: Younger patients who are ≤ 55 years of age, Caucasians or females with lung cancer have a higher risk of MDD. Particular attention should be given to them while being in the hospital which can decrease the morbidity, and will also help to improve their quality of life.

Factors Influencing Social Isolation and Loneliness Among Lung Cancer Patients: A Cross-sectional Study

2020 ◽  
Vol 40 (12) ◽  
pp. 7141-7145
Author(s):  
NANAMI ASHI ◽  
YUKI KATAOKA ◽  
TOMOYASU TAKEMURA ◽  
CHIGUSA SHIRAKAWA ◽  
KOYA OKAZAKI ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Cancer Patients ◽  
Social Isolation ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Lung Cancer Patients ◽  
Factors Influencing
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