scholarly journals The Structure of Urban Flows

2020 ◽  
Author(s):  
Pablo Torres ◽  
Soledad Le Clainche ◽  
Ricardo Vinuesa
Keyword(s):  
Thermal Effects ◽  
Physical Phenomenon ◽  
Pollutant Dispersion ◽  
Urban Environments ◽  
Data Driven ◽  
Thermal Fields ◽  
Use Of Data ◽  
Sustainability Challenges ◽  
The City ◽  
Insight Into

Understanding the flow in urban environments is an increasingly relevant problem due to its significant impact on air quality and thermal effects in cities worldwide. In this review we provide an overview of efforts based on experiments and simulations to gain insight into this complex physical phenomenon. We highlight the relevance of coherent structures in urban flows, which are responsible for the pollutant-dispersion and thermal fields in the city. We also suggest a more widespread use of data-driven methods to characterize flow structures as a way to further understand the dynamics of urban flows, with the aim of tackling the important sustainability challenges associated to them.

scholarly journals On the Experimental, Numerical and Data-Driven Methods to Study Urban Flows

Energies ◽  
2021 ◽  
Vol 14 (5) ◽  
pp. 1310
Author(s):  
Pablo Torres ◽  
Soledad Le Clainche ◽  
Ricardo Vinuesa
Keyword(s):  
Physical Phenomenon ◽  
Urban Pollution ◽  
Pollutant Dispersion ◽  
Urban Environments ◽  
Machine Learning Algorithms ◽  
Data Driven ◽  
Thermal Fields ◽  
Use Of Data ◽  
Sustainability Challenges ◽  
New Research

Understanding the flow in urban environments is an increasingly relevant problem due to its significant impact on air quality and thermal effects in cities worldwide. In this review we provide an overview of efforts based on experiments and simulations to gain insight into this complex physical phenomenon. We highlight the relevance of coherent structures in urban flows, which are responsible for the pollutant-dispersion and thermal fields in the city. We also suggest a more widespread use of data-driven methods to characterize flow structures as a way to further understand the dynamics of urban flows, with the aim of tackling the important sustainability challenges associated with them. Artificial intelligence and urban flows should be combined into a new research line, where classical data-driven tools and machine-learning algorithms can shed light on the physical mechanisms associated with urban pollution.

scholarly journals A Physical Organic Approach to Tuning Reagents for Selective and Stable Methionine Bioconjugation

2019 ◽  
Author(s):  
Alec Christian ◽  
Shang Jia ◽  
Patricia Zhang ◽  
Arismel Tena Meza ◽  
Matthew S. Sigman ◽  
...  
Keyword(s):  
Structural Features ◽  
Data Driven ◽  
Live Cells ◽  
Design And Synthesis ◽  
Use Of Data ◽  
Physical Organic ◽  
Driving Stability ◽  
Peptide Stapling ◽  
Insight Into ◽  
Unique Chemical

We report a data-driven, physical organic approach to the development of new methionine-selective bioconjugation reagents with tunable adduct stabilities. Statistical modeling of structural features described by intrinsic physical organic parameters was applied to the development of a predictive model and to gain insight into features driving stability of adducts formed from the chemoselective coupling of oxaziridine and methionine thioether partners through Redox Activated Chemical Tagging (ReACT). From these analyses, a correlation between sulfimide stabilities and sulfimide  (C=O) stretching frequencies was revealed. We ex-ploited the rational gains in adduct stability exposed by this analysis to achieve the design and synthesis of a bis-oxaziridine reagent for peptide stapling. Indeed, we observed that a macrocyclic peptide formed by ReACT stapling at methionine exhibited improved uptake into live cells compared to an unstapled congener, highlighting the potential utility of this unique chemical tool for thioether modification. This work provides a template for the broader use of data-driven approaches to bioconjugation chemistry and other chemical biology applications.

scholarly journals THE DUBLIN DASHBOARD: DESIGN AND DEVELOPMENT OF A REAL-TIME ANALYTICAL URBAN DASHBOARD

2016 ◽  
Vol III-4/W1 ◽  
pp. 19-25
Author(s):  
G. McArdle ◽  
R. Kitchin
Keyword(s):  
Real Time ◽  
Urban Environments ◽  
Water Levels ◽  
Time Data ◽  
Physical Size ◽  
The Public ◽  
Economic Output ◽  
Multiple Dimensions ◽  
The City ◽  
Insight Into

As many cities increase in size across multiple dimensions such as population, economic output and physical size, new methods for understanding and managing cities are required. Data produced by and about urban environments offer insight into what is happening in cities. Real-time data from sensors within the city record current transport and environmental conditions such as noise levels, water levels, journey times and public transport delays. Similarly administrative data such as demographics, employment statistics, property prices and crime rates all provide insight into how a city is evolving. Traditionally, these data were maintained separately and managed by individual city departments. Advances in technology and a move to open-government have placed many of these data in the public domain. Urban dashboards have emerged as a technique to visualise these data in an accessible way. This paper describes the implementation of one such dashboard, the Dublin Dashboard, an interactive website which collects, analyses and visualises data from a variety of sources about Dublin in Ireland through a series of interactive maps, graphs and applications. This paper describes the approach, the data and the technology used to develop the Dublin Dashboard and acts as a guideline for developing urban dashboards in other cities.

scholarly journals THE DUBLIN DASHBOARD: DESIGN AND DEVELOPMENT OF A REAL-TIME ANALYTICAL URBAN DASHBOARD

2016 ◽  
Vol IV-4/W1 ◽  
pp. 19-25 ◽  
Author(s):  
G. McArdle ◽  
R. Kitchin
Keyword(s):  
Real Time ◽  
Urban Environments ◽  
Water Levels ◽  
Time Data ◽  
Physical Size ◽  
The Public ◽  
Economic Output ◽  
Multiple Dimensions ◽  
The City ◽  
Insight Into

As many cities increase in size across multiple dimensions such as population, economic output and physical size, new methods for understanding and managing cities are required. Data produced by and about urban environments offer insight into what is happening in cities. Real-time data from sensors within the city record current transport and environmental conditions such as noise levels, water levels, journey times and public transport delays. Similarly administrative data such as demographics, employment statistics, property prices and crime rates all provide insight into how a city is evolving. Traditionally, these data were maintained separately and managed by individual city departments. Advances in technology and a move to open-government have placed many of these data in the public domain. Urban dashboards have emerged as a technique to visualise these data in an accessible way. This paper describes the implementation of one such dashboard, the Dublin Dashboard, an interactive website which collects, analyses and visualises data from a variety of sources about Dublin in Ireland through a series of interactive maps, graphs and applications. This paper describes the approach, the data and the technology used to develop the Dublin Dashboard and acts as a guideline for developing urban dashboards in other cities.

scholarly journals A Physical Organic Approach to Tuning Reagents for Selective and Stable Methionine Bioconjugation

2019 ◽  
Author(s):  
Alec Christian ◽  
Shang Jia ◽  
Patricia Zhang ◽  
Arismel Tena Meza ◽  
Matthew S. Sigman ◽  
...  
Keyword(s):  
Structural Features ◽  
Data Driven ◽  
Live Cells ◽  
Design And Synthesis ◽  
Use Of Data ◽  
Physical Organic ◽  
Driving Stability ◽  
Peptide Stapling ◽  
Insight Into ◽  
Unique Chemical

We report a data-driven, physical organic approach to the development of new methionine-selective bioconjugation reagents with tunable adduct stabilities. Statistical modeling of structural features described by intrinsic physical organic parameters was applied to the development of a predictive model and to gain insight into features driving stability of adducts formed from the chemoselective coupling of oxaziridine and methionine thioether partners through Redox Activated Chemical Tagging (ReACT). From these analyses, a correlation between sulfimide stabilities and sulfimide  (C=O) stretching frequencies was revealed. We ex-ploited the rational gains in adduct stability exposed by this analysis to achieve the design and synthesis of a bis-oxaziridine reagent for peptide stapling. Indeed, we observed that a macrocyclic peptide formed by ReACT stapling at methionine exhibited improved uptake into live cells compared to an unstapled congener, highlighting the potential utility of this unique chemical tool for thioether modification. This work provides a template for the broader use of data-driven approaches to bioconjugation chemistry and other chemical biology applications.

Minimetrò in Perugia as leverage for urban regeneration

TERRITORIO ◽  
2020 ◽  
pp. 148-163
Author(s):  
Luca Fondacci
Keyword(s):  
Urban Regeneration ◽  
Urban Environments ◽  
Low Carbon ◽  
Sustainable Mobility ◽  
Field Surveys ◽  
Peripheral Area ◽  
Alternative Means ◽  
Considerable Impact ◽  
The City ◽  
Historical Centre

In the 1970s, the fragile historical centre of the city of Perugia was a key area where the binomial of sustainable mobility and urban regeneration was developed and applied. At the turn of the xxi century, the low carbon automatic people-mover Minimetrò broadened that application from the city's historical centre to the outskirts, promoting the enhancement of several urban environments. This paper is the outcome of an investigation of original sources, field surveys and direct interviews, which addresses the Minimetrò as the backbone of a wide regeneration process which has had a considerable impact on the economic development of a peripheral area of the city which was previously devoid of any clear urban sense. The conclusion proposes some solutions to improve the nature of the Minimetrò as an experimental alternative means of transport.

Turkish Muslims in a German city: Entrepreneurial and residential self-determination

2015 ◽  
Vol 12 (1) ◽  
pp. 1-12
Author(s):  
Sarah Hackett
Keyword(s):  
Residential Patterns ◽  
Academic Literature ◽  
Self Employment ◽  
German City ◽  
Post War ◽  
Oral History Interviews ◽  
The City ◽  
Insight Into ◽  
Term Objective

Drawing upon a collection of oral history interviews, this paper offers an insight into entrepreneurial and residential patterns and behaviour amongst Turkish Muslims in the German city of Bremen. The academic literature has traditionally argued that Turkish migrants in Germany have been pushed into self-employment, low-quality housing and segregated neighbourhoods as a result of discrimination, and poor employment and housing opportunities. Yet the interviews reveal the extent to which Bremen’s Turkish Muslims’ performances and experiences have overwhelmingly been the consequences of personal choices and ambitions. For many of the city’s Turkish Muslim entrepreneurs, self-employment had been a long-term objective, and they have succeeded in establishing and running their businesses in the manner they choose with regards to location and clientele, for example. Similarly, interviewees stressed the way in which they were able to shape their housing experiences by opting which districts of the city to live in and by purchasing property. On the whole, they perceive their entrepreneurial and residential practices as both consequences and mediums of success, integration and a loyalty to the city of Bremen. The findings are contextualised within the wider debate regarding the long-term legacy of Germany’s post-war guest-worker system and its position as a “country of immigration”.

Food and Religious Identities in the Venetian Inquisition, ca. 1560–ca. 1640

2021 ◽  
Vol 74 (1) ◽  
pp. 181-214
Author(s):  
Eleanor Barnett
Keyword(s):  
Identity Construction ◽  
Religious Identity ◽  
Lived Religion ◽  
Ordinary People ◽  
Religious Identities ◽  
Access Points ◽  
Counter Reformation ◽  
Eating Practices ◽  
The City ◽  
Insight Into

Through Venetian Inquisition trials relating to Protestantism, witchcraft, and Judaism, this article illuminates the centrality of food and eating practices to religious identity construction. The Holy Office used food to assert its model of post-Tridentine piety and the boundaries between Catholics and the non-Catholic populations in the city. These trial records concurrently act as access points to the experiences and beliefs—to the lived religion—of ordinary people living and working in Venice from 1560 to 1640. The article therefore offers new insight into the workings and impacts of the Counter-Reformation.

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