Alterations in Food Reward Regarding Bariatric Surgery Type and Weight Loss Outcomes: An Exploratory Study

Changes in food preferences after bariatric surgery may alter its effectiveness as a treatment for obesity. We aimed to compare food reward for a comprehensive variety of food categories between patients who received a sleeve gastrectomy (SG) or a Roux-en-Y gastric bypass (RYGB) and to explore whether food reward differs according to weight loss. In this cross-sectional exploratory study, food reward was assessed using the Leeds Food Preference Questionnaire (LFPQ). We assessed liking and wanting of eleven food categories. Comparisons were done regarding type of surgery and Total Weight Loss (TWL; based on tercile distribution). Fifty-six patients (30 SG and 26 RYGB) were included (women: 70%; age: 44.0 (11.1) y). Regarding the type of surgery, scores were not significantly different between SG and RYGB, except for ‘non-dairy products – without color’ explicit liking (p = 0.04). Regarding TWL outcomes, explicit liking, explicit wanting and implicit wanting, scores were significantly higher for Good responders than Low responders for ‘No meat – High fat’ (post-hoc corrected p-value: 0.04, 0.03 and 0.04, respectively). Together, our results failed to identify major differences in liking and wanting regarding the type of surgery and tended to indicate that higher weight loss might be related to a higher reward for high protein-content food. Rather to focus only on palatable foods, future studies should also consider a broader range of food items, including protein reward.

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Is duodeno-jejunal bypass liner superior to pylorus preserving bariatric surgery in terms of complications and efficacy?

Langenbeck s Archives of Surgery ◽

10.1007/s00423-021-02131-x ◽

2021 ◽

Author(s):

Istvan Bence Balint ◽

Ferenc Csaszar ◽

Krisztian Somodi ◽

Laszlo Ternyik ◽

Adrienn Biro ◽

...

Keyword(s):

Bariatric Surgery ◽

Weight Loss ◽

Surgical Procedures ◽

Risk Level ◽

Jejunal Mucosa ◽

Complication Rates ◽

Pubmed Database ◽

Significant Difference ◽

Weight Loss Outcomes ◽

Jejunal Bypass

Abstract Purpose Based on recent scientific evidence, bariatric surgery is more effective in the management of morbid obesity and related comorbidities than conservative therapy. Pylorus preserving surgical procedures (PPBS) such as laparoscopic single-anastomosis duodeno-jejunal or duodeno-ileal bypass with sleeve gastrectomy are modified duodenal switch (DS) surgical techniques. The duodeno-jejunal bypass liner (DJBL) is a novel surgical method in the inventory of metabolism focused manual interventions that excludes duodeno-jejunal mucosa from digestion, mimicking DS procedures without the risk of surgical intervention. The aim of this article is to summarize and compare differences between safety-related features and weight loss outcomes of DJBL and PPBS. Methods A literature search was conducted in the PubMed database. Records of DJBL-related adverse events (AEs), occurrence of PPBS-related complications and reintervention rates were collected. Mean weight, mean body mass index (BMI), percent of excess of weight loss (EWL%), percent of total weight loss (TWL%) and BMI value alterations were recorded for weight loss outcomes. Results A total of 11 publications on DJBL and 6 publications on PPBS were included, involving 800 and 1462 patients, respectively. The baseline characteristics of the patients were matched. Comparison of DJBL-related AEs and PPBS-related severe complications showed an almost equal risk (risk difference (RD): −0.03 and confidence interval (CI): −0.27 to 0.21), despite higher rates among patients having received endoscopic treatment. Overall AE and complication rates classified by Clavien-Dindo showed that PPBS was superior to DJBL due to an excess risk level of 25% (RD: 0.25, CI: 0.01–0.49). Reintervention rates were more favourable in the PPBS group, without significant differences in risk (RD: −0.03, CI: −0.27 to 0.20). However, PPBS seemed more efficient regarding weight loss outcomes at 1-year follow-up according to raw data, while meta-analysis did not reveal any significant difference (odds ratio (OR): 1.08, CI: 0.74–1.59 for BMI changes). Conclusion Only limited conclusions can be made based on our findings. PPBS was superior to DJBL with regard to safety outcomes (GRADE IIB), which failed to support the authors’ hypothesis. Surgical procedures showed lower complication rates than the incidence of DJBL-related AEs, although it should be emphasized that the low number of PPBS-related mild to moderate complications reported could be the result of incomplete data recording from the analysed publications. Weight loss outcomes favoured bariatric surgery (GRADE IIB). As the DJBL is implanted into the upper gastrointestinal tract for 6 to 12 months, it seems a promising additional method in the inventory of metabolic interventions.

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Grazing Behavior Hinders Weight Loss in Long-Term Post Bariatric Surgery: a Cross-Sectional Study

Obesity Surgery ◽

10.1007/s11695-021-05533-4 ◽

2021 ◽

Author(s):

Larissa Cristina Lins Berber ◽

Mariana Silva Melendez-Araújo ◽

Eduardo Yoshio Nakano ◽

Kênia Mara Baiocchi de Carvalho ◽

Eliane Said Dutra

Keyword(s):

Bariatric Surgery ◽

Weight Loss ◽

Cross Sectional Study ◽

Sectional Study ◽

Cross Sectional ◽

Grazing Behavior ◽

Post Bariatric Surgery

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Food reward in the obese and after weight loss induced by calorie restriction and bariatric surgery

Annals of the New York Academy of Sciences ◽

10.1111/j.1749-6632.2012.06573.x ◽

2012 ◽

Vol 1264 (1) ◽

pp. 36-48 ◽

Cited By ~ 36

Author(s):

Hans‐Rudolf Berthoud ◽

Huiyuan Zheng ◽

Andrew C. Shin

Keyword(s):

Bariatric Surgery ◽

Weight Loss ◽

Calorie Restriction ◽

Food Reward

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Optimizing weight loss outcomes for bariatric surgery patients: the role of physical activity

BMC Proceedings ◽

10.1186/1753-6561-6-s4-o1 ◽

2012 ◽

Vol 6 (S4) ◽

Author(s):

R Boddu ◽

E Wilson ◽

B Snyder ◽

TD Wilson

Keyword(s):

Physical Activity ◽

Bariatric Surgery ◽

Weight Loss ◽

Weight Loss Outcomes

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Role of the FKBP5 polymorphism rs1360780, age, sex, and type of surgery in weight loss after bariatric surgery: a follow-up study

Surgery for Obesity and Related Diseases ◽

10.1016/j.soard.2019.12.002 ◽

2020 ◽

Vol 16 (4) ◽

pp. 581-589 ◽

Cited By ~ 5

Author(s):

Elionora Peña ◽

Assumpta Caixàs ◽

Concepción Arenas ◽

Mercedes Rigla ◽

Sara Crivillés ◽

...

Keyword(s):

Bariatric Surgery ◽

Weight Loss ◽

Follow Up Study ◽

Type Of Surgery

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Association of GWAS-Based Candidate Genes with HDL-Cholesterol Levels before and after Bariatric Surgery in the Swedish Obese Subjects Study

The Journal of Clinical Endocrinology & Metabolism ◽

10.1210/jc.2010-2227 ◽

2011 ◽

Vol 96 (6) ◽

pp. E953-E957 ◽

Cited By ~ 21

Author(s):

Mark A. Sarzynski ◽

Peter Jacobson ◽

Tuomo Rankinen ◽

Björn Carlsson ◽

Lars Sjöström ◽

...

Keyword(s):

Bariatric Surgery ◽

Weight Loss ◽

Candidate Genes ◽

Association Studies ◽

Statistical Significance ◽

Genome Wide Association Studies ◽

Nucleotide Polymorphisms ◽

Cross Sectional ◽

Time Points ◽

Obese Subjects

Context and Objective: The magnitude of weight loss-induced high-density lipoprotein cholesterol (HDL-C) changes may depend on genetic factors. We examined the associations of eight candidate genes, identified by genome-wide association studies, with HDL-C at baseline and 10 yr after bariatric surgery in the Swedish Obese Subjects study. Methods: Single-nucleotide polymorphisms (SNP) (n = 60) in the following gene loci were genotyped: ABCA1, APOA5, CETP, GALNT2, LIPC, LIPG, LPL, and MMAB/MVK. Cross-sectional associations were tested before (n = 1771) and 2 yr (n = 1583) and 10 yr (n = 1196) after surgery. Changes in HDL-C were tested between baseline and yr 2 (n = 1518) and yr 2 and 10 (n = 1149). A multiple testing corrected threshold of P = 0.00125 was used for statistical significance. Results: In adjusted multivariate models, CETP SNP rs3764261 explained from 3.2–4.2% (P < 10−14) of the variation in HDL-C at all three time points, whereas CETP SNP rs9939224 contributed an additional 0.6 and 0.9% at baseline and yr 2, respectively. LIPC SNP rs1077834 showed consistent associations across all time points (R2 = 0.4–1.1%; 3.8 × 10−6 < P < 3 × 10−3), whereas LPL SNP rs6993414 contributed approximately 0.5% (5 × 10−4 < P < 0.0012) at yr 2 and 10. In aggregate, four SNP in three genes explained 4.2, 6.8, and 5.6% of the HDL-C variance at baseline, yr 2, and yr 10, respectively. None of the SNP was significantly associated with weight loss-related changes in HDL-C. Conclusions: SNP in the CETP, LIPC, and LPL loci contribute significantly to plasma HDL-C levels in obese individuals, and the associations persist even after considerable weight loss due to bariatric surgery. However, they are not associated with surgery-induced changes in HDL-C levels.

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