scholarly journals Environmental exposure to cooking oil fumes and fatty liver disease

2020 ◽  
Vol 9 (6) ◽  
pp. 3810-3817
Author(s):  
Jie Lin ◽  
Saili Ni ◽  
Qili Shi ◽  
Zi Xiong ◽  
Junfei Kang ◽  
...  
Keyword(s):  
Liver Disease ◽  
Fatty Liver ◽  
Environmental Exposure ◽  
Fatty Liver Disease ◽  
Cooking Oil ◽  
Cooking Oil Fumes

scholarly journals Environmental Exposure to Cooking Oil Fume and Fatty Liver Disease

2020 ◽  
Author(s):  
Shun Zhang ◽  
Jie Lin ◽  
Saili Ni ◽  
Qili Shi ◽  
Zi Xiong ◽  
...  
Keyword(s):  
Logistic Regression ◽  
Liver Disease ◽  
Fatty Liver ◽  
Heavy Oil ◽  
Fatty Liver Disease ◽  
Exposure Group ◽  
Odds Ratios ◽  
Disease Extent ◽  
Cooking Oil ◽  
Stratified Analysis

Abstract Background: Evidence on effect of cooking oil fume, which contains numerous carcinogens, on development of fatty liver disease is limited. The present study aims to investigate the association between exposure to cooking oil fume and the risk of fatty liver disease.Method: A total of 55959 participants aged between 40 and 75 years old participated in a community-based survey in Ningbo, China. Information on exposure to cooking oil fume and fatty liver disease were collected by face-to-face interview. Stratified analysis was used with participants being divided into two groups according to gender. Multiple logistic regression analyses were conducted to investigate the association between cooking oil fume exposure and fatty liver risk. Furthermore, ordered logistic regression was conducted to investigate the association between cooking oil fume exposure and the severity of fatty liver disease.Results: Fatty liver disease prevalence was 8.79% in none oil fume exposure group, 10.52% in light oil fume exposure group, 23.47% in moderate oil fume exposure group and 41.45% in heavy oil fume exposure group. After adjusting for confounding factors, participants in the light, moderate and heavy cooking oil fume exposure groups all had significantly higher odds ratios as compared with participants in the none oil fume exposure group. In addition, an interaction effect between cooking oil fume exposure and gender on the prevalence and severity of fatty liver disease was observed. Females with heavyoil fume exposure had the highest odds ratios of fatty liver disease and severer disease extent. In the stratified analysis, compared to participants in the smokeless group, males and females in light, moderate and heavy cooking oil fume exposure groups all had significantly higher risk of fatty liver disease and severer disease extent, while participants with heavier cooking oil fume exposure tended to have higher risk of fatty liver disease and severer disease extent.Conclusion: Exposure to cooking oil fume is associated with incident and severity of fatty liver disease in 40-75 years old Chinese. The associations might be dose-responsive. In addition, heavy oil fume exposure and female sex might have a synergistic effecton incident and severity of fatty liver disease.

scholarly journals Environmental Exposure to Cooking Oil Fume and Fatty Liver Disease: a cross-sectional study.

2020 ◽  
Author(s):  
Shun Zhang ◽  
Jie Lin ◽  
Saili Ni ◽  
Qili Shi ◽  
Zi Xiong ◽  
...  
Keyword(s):  
Logistic Regression ◽  
Liver Disease ◽  
Fatty Liver ◽  
Heavy Oil ◽  
Fatty Liver Disease ◽  
Cross Sectional Study ◽  
Disease Extent ◽  
Cross Sectional ◽  
Cooking Oil ◽  
Stratified Analysis

Abstract Background The effect of cooking oil fume on development of fatty liver disease is limited. The present study aims to investigate the association between exposure to cooking oil fume and the risk of fatty liver disease. Method A total of 55959 participants aged between 40 and 75 years old participated in a community-based survey in Ningbo, China. Multiple logistic regression analyses were conducted to investigate the association between cooking oil fume exposure and fatty liver risk. Furthermore, ordered logistic regression was conducted to investigate the association between cooking oil fume exposure and the severity of fatty liver disease. Results Cooking oil fume exposure were significantly associated with fatty liver disease after adjusting for confounding factors compared with participants in the none oil fume exposure group. Moreover, interaction analyses indicated that females with heavy oil fume exposure had the highest odds ratios of fatty liver disease and severer disease extent. In the stratified analysis, compared to participants in the smokeless group, males and females in light, moderate and heavy cooking oil fume exposure groups all had significantly higher risk of fatty liver disease and severer disease extent, while participants with heavier cooking oil fume exposure tended to have higher risk of fatty liver disease and severer disease extent. Conclusion Our findings indicated that exposure to cooking oil fume potentiated the risk of fatty liver disease, and the associations might be dose-responsive. Furthermore, heavy oil fume exposure and female sex might have a synergistic effect on fatty liver disease.

Vitamin D levels are not associated with non-alcoholic fatty liver disease severity in a Brazilian population

2020 ◽  
pp. 1-8
Author(s):  
Jeniffer Danielle M. Dutra ◽  
Quelson Coelho Lisboa ◽  
Silvia Marinho Ferolla ◽  
Carolina Martinelli M. L. Carvalho ◽  
Camila Costa M. Mendes ◽  
...  
Keyword(s):  
Vitamin D ◽  
Liver Disease ◽  
Fatty Liver ◽  
Disease Severity ◽  
Fatty Liver Disease ◽  
Hypovitaminosis D ◽  
Alcoholic Fatty Liver ◽  
Vitamin D Levels ◽  
The Mean ◽  
Alcoholic Fatty Liver Disease

Abstract. Some epidemiological evidence suggests an inverse correlation between non-alcoholic fatty liver disease (NAFLD) frequency and vitamin D levels. Likewise, a beneficial effect of vitamin D on diabetes mellitus (DM) and insulin resistance has been observed, but this is an unsolved issue. Thus, we aimed to investigate the prevalence of hypovitaminosis D in a NAFLD Brazilian population and its association with disease severity and presence of comorbidities. In a cross-sectional study, the clinical, biochemical and histological parameters of 139 NAFLD patients were evaluated according to two different cut-off points of serum 25-hydroxyvitamin D levels (20 ng/mL and 30 ng/mL). The mean age of the population was 56 ± 16 years, most patients were female (83%), 72% had hypertension, 88% dyslipidemia, 46% DM, 98% central obesity, and 82% metabolic syndrome. Serum vitamin D levels were < 30 ng/mL in 78% of the patients, and < 20 ng/mL in 35%. The mean vitamin D level was 24.3 ± 6.8 ng/mL. The comparison between the clinical, biochemical and histological characteristics of the patients according to the levels of vitamin D showed no significant difference. Most patients with NAFLD had hypovitaminosis D, but low vitamin D levels were not related to disease severity and the presence of comorbidities.

Non-Alcoholic Fatty Liver Disease in Overweight Children and its Relationship with Retinol Serum Levels

2008 ◽  
Vol 78 (1) ◽  
pp. 27-32 ◽  
Author(s):  
Suano de Souza ◽  
Silverio Amancio ◽  
Saccardo Sarni ◽  
Sacchi Pitta ◽  
Fernandes ◽  
...  
Keyword(s):  
Insulin Resistance ◽  
Liver Disease ◽  
Fatty Liver ◽  
Lipid Profile ◽  
Fatty Liver Disease ◽  
Thiobarbituric Acid ◽  
Serum Levels ◽  
Control Group ◽  
Alcoholic Fatty Liver ◽  
Alcoholic Fatty Liver Disease

Objectives: To evaluate the frequency of non-alcoholic fatty liver disease, the retinol serum levels, lipid profile, and insulin resistance in overweight/obese children. To relate these biochemical variables with the risk of this disease in the population studied. Methods: The study was cross-sectional and prospective, with 46 overweight/obese school children (28 female, 18 male; mean age 8.6 years). The control group consisted of 45 children, paired by age and gender. Hepatic steatosis, evaluated by ultrasound, was classified as normal, mild, moderate, or severe. Also evaluated were serum retinol levels; thiobarbituric acid reactive substances; lipid profile; and fasting glucose and serum insulin levels, used for the calculation of the Homeostasis Model Assessment. Results: Hepatic ultrasound alterations were found in 56.5% and 48,9% of the overweight/obese and control group children, respectively. Presence of obesity was associated with high levels of triglycerides (OR = 4.6; P = 0.002). In the studied children, the risk of steatosis was related to a trend to a higher percentage of retinol inadequacy (OR = 2.8; p = 0.051); there was no association with thiobarbituric acid reactive substances, lipid profile, or insulin resistance. Conclusions: The high frequency of non-alcoholic fatty liver disease in both groups, evaluated by hepatic ultrasound, in low-socioeconomic level children, independent of nutritional condition and without significant association with insulin resistance, emphasizes that especially in developing countries, other risk factors such as micronutrient deficiencies (e.g. vitamin A) are involved.

Sign in / Sign up

Export Citation Format

Share Document