scholarly journals COVID-19 Infection among People with HIV/AIDS in Africa: Knowledge Gaps, Public Health Preparedness and Research Priorities

2021 ◽  
Vol 10 (1) ◽  
pp. 113-118
Author(s):  
Ekere James Essien ◽  
Osaro Mgbere ◽  
Sorochi Iloanusi ◽  
Susan V. Abughosh

The emergence of novel virus SARS-CoV-2 that causes COVID-19 has complicated Africa’s public health challenges, especially with the pre-existing epidemics such as HIV/AIDS. We highlight the known evidence related to COVID-19 infections among people with HIV (PWH) with specific reference to Africa. The knowledge gaps, level of public health preparedness and the potential research priorities are also outlined. Although the epidemiology and clinical course of COVID-19 in HIV patients are evolving, existing evidence indicate that the disease outcomes are comparable to that of the general population. However, PWH with low CD4 cell counts may have worse outcomes than individuals with restored immunity, whereas old age and co-morbidities such as obesity, hypertension and diabetes can further increase their overall risk. While there may be slight disruption of HIV service delivery in selected African countries, the resilience and resourcefulness of others have helped to sustain HIV service delivery and enhanced the level of public health preparedness and fight against the pandemic. The paucity of data and research studies on HIV-COVID-19 coinfection in Africa, call for concerted efforts to address these limitations. Keywords: • COVID-19 • SARS-CoV-2 • HIV • PWH • Public Health • Research • Africa   Copyright © 2021 Essien, et al. Published by Global Health and Education Projects, Inc. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY 4.0) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work, first published in this journal, is properly cited.

2017 ◽  
Vol 107 (7) ◽  
pp. 1045-1047 ◽  
Author(s):  
Emily F. Rothman ◽  
Hanni Stoklosa ◽  
Susie B. Baldwin ◽  
Makini Chisolm-Straker ◽  
Rumi Kato Price ◽  
...  

Author(s):  
William Evans ◽  
Kuyosh Kadirov ◽  
Ibou Thior ◽  
Ramakrishnan Ganesan ◽  
Alec Ulasevich ◽  
...  

HIV/AIDS and other sexually transmitted infections (STIs) continue to be among the greatest public health threats worldwide, especially in sub-Saharan Africa (SSA). Condom use remains an essential intervention to eradicate AIDS, and condom use is now higher than ever. However, free and subsidized condom funding is declining. Research on how to create healthy markets based on willingness to pay for condoms is critically important. This research has three primary aims: (1) willingness of free condom users in five African countries to pay for socially marketed condoms; (2) the relationship between specific population variables and condom brand marketing efforts and willingness to pay; and (3) potential opportunities to improve condom uptake. Nationally representative samples of at least 1200 respondents were collected in Kenya, Nigeria, South Africa, Zambia, and Zimbabwe. We collected data on a range of demographic factors, including condom use, sexual behavior, awareness of condom brands, and willingness to pay. We estimated multivariate linear regression models and found that free condom users are overwhelmingly willing to pay for condoms overall (over 90% in Nigeria) with variability by country. Free users were consistently less willing to pay for condoms if they had a positive identification with their free brand in Kenya and Zimbabwe, suggesting that condom branding is a critical strategy. Ability to pay was negatively correlated with willingness, but users who could not obtain free condoms were willing to pay for them in Kenya and Zimbabwe. In a landscape of declining donor funding, this research suggests opportunities to use scarce funds for important efforts such as campaigns to increase demand, branding of condoms, and coordination with commercial condom manufacturers to build a healthy total market approach for the product. Free condoms remain an important HIV/AIDS prevention tool. Building a robust market for paid condoms in SSA is a public health priority.


2001 ◽  
Vol 13 (2) ◽  
pp. 113-126 ◽  
Author(s):  
Janet E. Fulton ◽  
Charlene R. Burgeson ◽  
Geraldine R. Perry ◽  
Bettylou Sherry ◽  
Deborah A. Galuska ◽  
...  

An expert panel workshop had two specific aims: (a) to review the current state of knowledge of existing methods for assessing physical activity and sedentary behavior in order to determine their reliability, validity, feasibility, strengths, and limitations and (b) to set research priorities and recommendations to enable the use of reliable and valid instruments for assessing physical activity and sedentary behavior within the context of three public health functions for children ages 2–5 years. Experts presented four major recommendations for research priorities at the conclusion of the 2-day workshop. The need to develop valid methods for measuring physical activity and sedentary behavior was considered the necessary first step to accomplish meaningful physical activity surveillance, public health research, and intervention research for children ages 2–5 years.


2009 ◽  
Vol 7 (1) ◽  
Author(s):  
Mark McCarthy ◽  
Gabrielle Harvey ◽  
Claudia Conceição ◽  
Giuseppe la Torre ◽  
Gabriel Gulis

2009 ◽  
Vol 6 (4) ◽  
pp. 224-231 ◽  
Author(s):  
Aranka Anema ◽  
Nicholas Vogenthaler ◽  
Edward A. Frongillo ◽  
Suneetha Kadiyala ◽  
Sheri D. Weiser

2021 ◽  
Vol 9 ◽  
Author(s):  
Mohannad Al Nsour ◽  
Tala Chahien ◽  
Yousef Khader ◽  
Mirwais Amiri ◽  
Hana Taha

Research is essential for evidence-based decision making. This study aimed to identify research priorities in the areas of field epidemiology and public health in the Eastern Mediterranean Region (EMR) from the perspectives of public health professionals. A Delphi technique, using online survey, was employed to reach 168 public health professionals who have experience in the EMR countries. The study took place between November 2019 and January 2020. Consensus on the research priorities was reached after two-round online questionnaires. A list of top 10 field epidemiology and public health research priorities in the EMR was developed. Of those priorities, four fell under health in emergency, war and armed conflict, two under communicable diseases, two under immunization, one under digital health, and one under sexual, reproductive, and adolescent health. Availability, adequacy, and quality of health services in crisis settings were scored as a top priority (mean = 4.4, rank 1), followed by use of technology to improve the collection, documentation, and analysis of health data (mean = 4.28, rank 2), and capacity of countries in the region to respond to emergencies (mean = 4.25, rank 3). This study was conducted prior to COVID-19 pandemic and, thus, it did not capture COVID-19 research as a priority area. Nevertheless, identified priorities under communicable diseases including outbreak investigation of infectious diseases, epidemics and challenges related to communicable diseases in the EMR were still notable. In conclusion, the field epidemiology and public health research priorities identified in this study through a systematic inclusive process could be useful to make informed decisions and gear the research efforts to improve the health of people in the EMR.


2013 ◽  
Vol 6 (1) ◽  
pp. 22448 ◽  
Author(s):  
Peter Byass ◽  
Clara Calvert ◽  
Jessica Miiro-Nakiyingi ◽  
Tom Lutalo ◽  
Denna Michael ◽  
...  

2020 ◽  
Vol 21 (4) ◽  
pp. 272-283
Author(s):  
E.E. Igomu

Salmonella Kentucky is ubiquitous in most African countries and the multidrug resistant (MDR) strains remain underreported across the continent. In Nigeria, poverty, inter country livestock trades, nomadic system of cattle production, indiscriminate use of antibiotics and prevalent immuno-compromising diseases such as human immunodeficiency virus/acquired immune deficiency syndrome (HIV/AIDS) and tuberculosis are factors that have enabled ease of transmission and complications of S. Kentucky infections. In the present decade, S. Kentucky is reported to be the most prevalent serovar associated with poultry in Nigeria, but very few reports underline the risk associated with consumption of poultry and acquisition of MDR S. Kentucky strains. The Nigerian poultry is one of the most commercialized subsectors of Nigerian agriculture, therefore, the presence of S. Kentucky especially strains carrying broad spectrum antimicrobial resistance pose a great risk to public health. The lack of proper monitoring, surveillance, isolation and control of the multidrug resistant S. Kentucky will remain a challenge to the export potential of the Nigerian poultry subsector and livestock in general. As a nation, modalities and actions against the smuggling of poultry products, indiscriminate use of antibiotics and nomadic system for the production of dairy and beef that promotes spread of virulent strains of Salmonellae must change. The impact of non-typhoidal salmonellosis in humans in Nigeria also remains under studied and under reported, especially those caused by S. Kentucky ST198. Compounding these concerns is the lack of commercial veterinary or human vaccines against S. Kentucky or where vaccines against the broad serogroup C non-typhoidal Salmonella (NTS) are available, they are rarely supplied, with no evidence they could be cross-protective. This review emphasizes the emergence and widespread occurrence of MDR S. Kentucky strains on the African continent, and discussed risk factors contributing to its spread in Nigeria and the potential public health challenge especially to high-risk immunocompromised individuals. Keywords: Salmonella Kentucky, ST198 strain, multidrug resistant, tuberculosis, HIV/AIDS, Nigeria, Africa French Title: Salmonella Kentucky: prévalence et défis au Nigeria et sur le continent africain Salmonella Kentucky est omniprésente dans la plupart des pays africains et les souches multirésistantes (MDR) restent sous-déclarées à travers le continent. Au Nigéria, la pauvreté, les échanges de bétail entre pays, le système d'élevage nomade, l'utilisation aveugle d'antibiotiques et les maladies immunodéprimantes prévalentes telles que le virus de l'immunodéficience humaine/le syndrome d'immunodéficience acquise (VIH/SIDA) et la tuberculose sont des facteurs qui ont facilité la transmission et complications des infections à S. Kentucky. Au cours de la présente décennie, S. Kentucky serait le sérotype le plus répandu associé à la volaille au Nigéria, mais très peu de rapports soulignent le risque associé à la consommation de volaille et à l'acquisition de souches MDR S. Kentucky. La volaille nigériane est l'un des sous-secteurs les plus commercialisés de l'agriculture nigériane, par conséquent, la présence de S. Kentucky, en particulier les souches présentant une résistance antimicrobienne à large spectre, pose un grand risque pour la santé publique. L'absence de suivi, de surveillance, d'isolement et de contrôle adéquats du S. Kentucky multirésistant résistera toujours au défi du potentiel d'exportation du sous-secteur de la volaille nigérian et du bétail en général. En tant que nation, les modalités et les actions contre la contrebande de produits de volaille, l'utilisation aveugle d'antibiotiques et le système nomade pour la production de produits laitiers et de boeuf qui favorisent la propagation de souches virulentes de salmonelles doivent changer. L'impact de la salmonellose non typhoïde chez l'homme au Nigeria reste également sous-étudié et sous-signalé, en particulier ceux causés par S. Kentucky ST198. À ces inquiétudes s'ajoute le manque de vaccins commerciaux vétérinaires ou humains contre S. Kentucky ou là où des vaccins contre les Salmonella non typhoïde du sérogroupe C sont disponibles, ils sont rarement fournis, sans aucune preuve qu'ils pourraient être de protection croisée. Cette revue met l'accent sur l'émergence et la présence généralisée de souches MDR S. Kentucky sur le continent africain, et a discuté des facteurs de risque contribuant à sa propagation au Nigéria et du défi potentiel de santé publique en particulier pour les personnes immunodéprimées à haut risque. Mots-clés: Salmonella Kentucky, souche ST198, multirésistante, tuberculose, VIH/SIDA, Nigéria, Afrique  


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